Lopende en toekomstige projecten CMI NEN



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Lopende en toekomstige projecten CMI NEN Matchmaking Event Prof. Dr. Matthijs Oudkerk, Medical Scientific Director CMI NEN, Groningen Prof. Dr. Vinod Subramaniam, Technical Scientific Director CMI NEN, Twente Prof. Dr. Peter Vooijs, Supervisory Board CMI NEN, Twente Ing. Kees Smaling, Director CMI NEN, Siemens

WHO Programme: Priority Medical Devices In 2007 the World Health Organization (WHO), in collaboration with the Government of the Netherlands, launched the "Priority Medical Devices" project to determine whether medical devices currently on the market were meeting the needs of health care providers and end-users throughout the world and if not, to propose research to identify and action to remedy inadequacies or shortcomings. The aim of the project is to bring medical devices to the attention of policy makers and to help guide both industry and government public health spending.

Dutch programme development of Priority Medical Devices 2007-2010 Launch of New Medical Devices (NIG) by FOM, STW, ICTRegie, ZonMW, NWO. Fase I: 100 project proposals submitted (April 2009) Fase II: 24 Center proposals (May 2009) 14 Center propositions (December 2009) International Review Panel review (Finalized August 2010) IMDI.nl launch at Health&Technology Congress by WHO PMDproject leader, Ms. J. Hansen (15 sept 2010) Public presentation of the IMDI.nl by the chairman of the scientific council for government policy (WRR), Prof. A Knottnerus, and introduction of 8 Centers of Research Excellence (CoREs) on November 18, 2010. Positioning of IMDI in TOP sectors Life Science and HTMS (Sept 2011)

Bedrijfspartners Advanced Neuro Technology Biomade Brainlab Circle Cardiovascular Imaging Danone Delft Diagnostic Imaging Demcon Eckert & Ziegler Euro-Diagnostics Future Diagnostics GE Healthcare Guerbet Nederland BV Lead Pharma Medis Leiden MeVis Oldelft Pie Medical QC1 Raytest Roche Rogan Delft Terarecon Inc TMS International TNO Veenstra Instruments Vital Images Ytec Imaging BV ZioSoft

CMI NEN Research Project Development International Scientific Advisory Board Industrial Advisory Board advice CMI Foundation Supervisory Board CMI Clinical Advisory Committee research demand Research Committee Board of Directors C M I D I S C I P L I N E S Ultrasound Optics Magnetic Resonance X-Ray Molecular Imaging Targeted Contrast Navigation Technology Med Imaging Informatics MTA staff Project Group Oncology Coordinator staff PhD MSc Students Project Group Cardio- Vascular Coordinator staff PhD MSc Students Project Group Neuro- Muscular Coordinator staff PhD MSc Students

CMI NEN Research Project Development CMI is the first research program in medical imaging deriving its research agenda from clinical demand with a focus on business opportunities

Matchmaking Outcomes CMI NEN Matchmaking Event, 12 oktober 2011 Discipline Group CT/ X-ray MRI Minimally invasive / Optics Molecular Imaging Medical Imaging Informatics Medical Technology Assessment Clinical leader (UMCG/UMCN) Rozemarijn Vliegenthart MD, PhD Bauke de Jong MD, PhD (chairman) Go van Dam MD, PhD Riemer Slart MD, PhD (chairman) Peter van Ooijen, PhD (chairman) Prof. Edwin van den Heuvel, PhD Technical leader (UTwente) Prof. Kees Slump PhD (chairman) Christian Beckmann PhD Prof. Wiendelt Steenbergen PhD (chairman) Prof. Leon Terstappen MD, PhD Ander de Keijzer PhD Prof. Maarten IJzerman PhD (chairman)

Matchmaking Outcomes CMI NEN Matchmaking Event, 12 oktober 2011 Discipline Group CT/ X-ray MRI Minimally invasive / Optics Molecular Imaging Medical Imaging Informatics Medical Technology Assessment Examples of current and future projects CT Myocardial Perfusion (VENI), NELSON, HAmel, Ground2 New diagnostic workup in breast cancer, TREADMILL, VENOUS Tumor-specific fluorescence imaging, MIRIAM (Minimally Invasive Robotics in an MRI Environment) TREADMILL, Tracer development CMI NEN Research Infrastructure, ESRON, HAmel, TREADMILL TREADMILL, HAmel, NELSON, New diagnostic workup in breast cancer

Diagnostic imaging network of the top national research centers regarding PET and high-field MR technology into one platform (TREADMILL TRacer Evaluation And Development in Magnetic Imaging Laboratories) Human (simultaneous and sequential) PET-MRI will be validated regarding possible indications in the major domains on brain, oncological, cardiovascular and inflammatory/infectious disorders Implementation according to health technology assessment (HTA) outcomes TREADMILL

TREADMILL Neuro: methods that relate different time-scales of variations in brain function functional receptor binding / network activation studies Applications in Parkinson's disease, Alzheimer's disease, Diffuse Lewy Body Disease and Traumatic Brain Injury. Oncology: High resolution visualization and demarcation of the uptake of specific radiotracers (PET) combined with information on tumor vasculature Identification of possible radioresistant subregions within tumors for radiation dose escalation Early response monitoring for decision making for further treatment including systemic anticancer therapy Better visualization and demarcation of critical normal structures More reproducible methods to assess late radiation-induced side effects following treatment Cardiovascular: detection of CAD using angiography combined with the reference method of PET for the evaluation of myocardial perfusion reserve atherosclerotic plaque characterization imaging of stem cells and evaluation of angiogenesis

Medical Technology Assessment in TREADMILL Door de MTA disciplinegroep worden de volgende aaneensluitende stappen gedefinieerd: 1. Hierarchische analyse van klinische categorieen voor de optimale toepassingen van PET-MRI. 2. Hoofdruimte analyse en vroeg (Bayesiaans) economisch model voor het prioreren van de gevonden toepassingen. 3. Workflow analyse van het huidige klinische traject en de waarschijnlijke veranderingen bij toepassingen van de Siemens Biograph mmr en de Philips Ingenuity TF systemen in termen van mankracht en het gebruik van resources. 4. Schatting van diagnostisch volume en fasering van implementatie trajecten.

CMI ICT Infrastructuur CMI multi-center digitale infrastructuur omvat: 1. Beeldopslag en distributie platform 2. Klinisch Research Informatie Systeem 3. Geavanceerde visualizatie en beeldbewerking 4. Data mining 5. Geavanceerde server, opslag en computing faciliteiten Donald Smits Center for Information Technology (CIT), University of Groningen

UMCG facilities support a wide variety of medical and life sciences research

http://www.cmi-nen.nl

Vital Images, a CMI partner Dank voor uw aandacht