Creation Date 18-Jun-2007 Product Name SAFETY DATA SHEET 1. Identification 1,4-Naphthoquinone, contains up to 6% moisture Revision Number 2 Cat No. : Synonyms Recommended Use AC166710000; AC166710025; AC166710050; AC166711000; AC166715000 1,4-Naphthalenedione Laboratory chemicals. Uses advised against No Information available Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100 Entity / Business Name Acros Organics One Reagent Lane Fair Lawn, NJ 07410 Emergency Telephone Number For information US call: 001-800-ACROS-01 / Europe call: +32 14 57 52 11 Emergency Number US:001-201-796-7100 / Europe: +32 14 57 52 99 CHEMTREC Tel. No.US:001-800-424-9300 / Europe:001-703-527-3887 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Acute oral toxicity Category 3 Acute dermal toxicity Category 3 Acute Inhalation Toxicity - Dusts and Mists Category 1 Skin Corrosion/irritation Category 1 B Serious Eye Damage/Eye Irritation Category 1 Skin Sensitization Category 1 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. Label Elements Signal Word Danger Hazard Statements Toxic if swallowed Toxic in contact with skin Fatal if inhaled Causes severe skin burns and eye damage Causes serious eye damage May cause an allergic skin reaction May cause respiratory irritation Page 1 / 8
Precautionary Statements Prevention Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear protective gloves/protective clothing/eye protection/face protection Do not breathe dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area In case of inadequate ventilation wear respiratory protection Contaminated work clothing should not be allowed out of the workplace Response Call a POISON CENTER or doctor/physician if you feel unwell Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Immediately call a POISON CENTER or doctor/physician Skin Immediately call a POISON CENTER or doctor/physician Wash contaminated clothing before reuse IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower If skin irritation or rash occurs: Get medical advice/attention Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Ingestion Rinse mouth Do NOT induce vomiting IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Storage Store locked up Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) Very toxic to aquatic life May form combustible dust concentrations in air 3. Composition / information on ingredients Component CAS-No Weight % 1,4-Naphthalenedione 130-15-4 >95 Water 7732-18-5 <5 4. First-aid measures Eye Contact Skin Contact Inhalation Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth Page 2 / 8
resuscitation if victim ingested or inhaled the substance; induce artificial respiration with a respiratory medical device. Immediate medical attention is required. Ingestion Most important symptoms/effects Notes to Physician Suitable Extinguishing Media Unsuitable Extinguishing Media Do not induce vomiting. Call a physician or Poison Control Center immediately. May cause allergic skin reaction.. Causes burns by all exposure routes. Symptoms of allergic reaction may include rash, itching, swelling, trouble breathing, tingling of the hands and feet, dizziness, lightheadedness, chest pain, muscle pain or flushing: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation Treat symptomatically 5. Fire-fighting measures Water spray. Carbon dioxide (CO 2). Dry chemical. chemical foam. Flash Point 141 C / 285.8 F Method - Autoignition Temperature Explosion Limits Upper Lower Sensitivity to Mechanical Impact Sensitivity to Static Discharge Specific Hazards Arising from the Chemical Dust can form an explosive mixture in air. Do not allow run-off from fire fighting to enter drains or water courses. Hazardous Combustion Products Carbon monoxide (CO) Carbon dioxide (CO2) Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health 4 Flammability 1 Instability 1 Physical hazards N/A Personal Precautions Environmental Precautions 6. Accidental release measures Ensure adequate ventilation. Use personal protective equipment. Do not flush into surface water or sanitary sewer system. Do not allow material to contaminate ground water system. Prevent product from entering drains. Local authorities should be advised if significant spillages cannot be contained. See Section 12 for additional ecological information. Avoid release to the environment. Collect spillage. Methods for Containment and Clean Avoid dust formation. Prevent product from entering drains. Sweep up or vacuum up Up spillage and collect in suitable container for disposal. Do not flush into surface water or sanitary sewer system. Handling Storage 7. Handling and storage Do not breathe dust. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Use only in area provided with appropriate exhaust ventilation. Wear personal protective equipment. Keep in a dry, cool and well-ventilated place. Keep container tightly closed. Page 3 / 8
Exposure Guidelines 8. Exposure controls / personal protection This product does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Skin and body protection Respiratory Protection Hygiene Measures Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Wear appropriate protective gloves and clothing to prevent skin exposure. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. 9. Physical and chemical properties Physical State Powder Solid Appearance Beige Odor irritating Odor Threshold ph 6.1 10g/l aq.sol Melting Point/Range 128.5 C / 263.3 F Boiling Point/Range Flash Point 141 C / 285.8 F Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Relative Density 1.422 Solubility Partition coefficient; n-octanol/water Autoignition Temperature Decomposition Temperature Viscosity Molecular Formula C10 H6 O2 Molecular Weight 158.16 10. Stability and reactivity Reactive Hazard Stability Conditions to Avoid Incompatible Materials None known, based on information available Stable under normal conditions. Incompatible products. Exposure to light. Strong oxidizing agents, Strong reducing agents Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2) Page 4 / 8
Hazardous Polymerization Hazardous Reactions Acute Toxicity Hazardous polymerization does not occur. None under normal processing. 11. Toxicological information Product Information Oral LD50 Category 3. Dermal LD50 Category 3. Mist LC50 Category 1. Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation 1,4-Naphthalenedione 190 mg/kg ( Rat ) 202 mg/kg ( Rat ) LC50: 0.046 mg/l/4h (Rat) Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity Causes burns by all exposure routes May cause sensitization by skin contact The table below indicates whether each agency has listed any ingredient as a carcinogen. Component CAS-No IARC NTP ACGIH OSHA Mexico 1,4-Naphthalenedione 130-15-4 Not listed Not listed Not listed Not listed Not listed Water 7732-18-5 Not listed Not listed Not listed Not listed Not listed Mutagenic Effects Ames test: positive. Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Aspiration hazard... Respiratory system None known Symptoms / effects,both acute and delayed Endocrine Disruptor Information Symptoms of allergic reaction may include rash, itching, swelling, trouble breathing, tingling of the hands and feet, dizziness, lightheadedness, chest pain, muscle pain or flushing: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation Other Adverse Effects Ecotoxicity Very toxic to aquatic organisms. Persistence and Degradability Bioaccumulation/ Accumulation The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information. 12. Ecological information Persistence is unlikely. Mobility. Page 5 / 8
Component log Pow 1,4-Naphthalenedione 1.78 Waste Disposal Methods 13. Disposal considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. Component RCRA - U Series Wastes RCRA - P Series Wastes 1,4-Naphthalenedione - 130-15-4 U166-14. Transport information DOT UN-No UN2928 Proper Shipping Name Toxic solid, corrosive, organic, n.o.s Proper technical name 1,4-Naphthalenedione Hazard Class 6.1 Subsidiary Hazard Class 8 Packing Group I TDG UN-No UN2928 Proper Shipping Name TOXIC SOLID, CORROSIVE, ORGANIC, N.O.S. Hazard Class 6.1 Subsidiary Hazard Class 8 Packing Group I IATA UN-No UN2928 Proper Shipping Name TOXIC SOLID, CORROSIVE, ORGANIC, N.O.S. Hazard Class 6.1 Subsidiary Hazard Class 8 Packing Group I IMDG/IMO UN-No UN2928 Proper Shipping Name TOXIC SOLID, CORROSIVE, ORGANIC, N.O.S. Hazard Class 6.1 Subsidiary Hazard Class 8 Packing Group I International Inventories 15. Regulatory information Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL 1,4-Naphthalenedione X X - 204-977-6 - X X X X X Water X X - 231-791-2 - X - X X X Legend: X - Listed E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA. F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA. N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used. P - Indicates a commenced PMN substance R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA. S - Indicates a substance that is identified in a proposed or final Significant New Use Rule T - Indicates a substance that is the subject of a Section 4 test rule under TSCA. XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base Production and Site Reports (40 CFR 710(B). Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater. Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. Page 6 / 8
U.S. Federal Regulations TSCA 12(b) SARA 313 SARA 311/312 Hazardous Categorization Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Yes No Yes No No Clean Water Act Clean Air Act OSHA Occupational Safety and Health Administration CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) Component Hazardous Substances RQs CERCLA EHS RQs 1,4-Naphthalenedione 5000 lb - California Proposition 65 This product does not contain any Proposition 65 chemicals State Right-to-Know Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island 1,4-Naphthalenedione X X X - - Water - - X - - U.S. Department of Transportation Reportable Quantity (RQ): DOT Marine Pollutant DOT Severe Marine Pollutant N N N U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico - Grade Canada This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR WHMIS Hazard Class D1A Very toxic materials D2B Toxic materials B4 Flammable solid E Corrosive material Page 7 / 8
Prepared By 16. Other information Regulatory Affairs Thermo Fisher Scientific Email: EMSDS.RA@thermofisher.com Creation Date Revision Date Print Date Revision Summary 18-Jun-2007 21-Apr-2015 21-Apr-2015 This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR 1910.1200 to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) Disclaimer The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of SDS Page 8 / 8