Yavuz Selim Yıldırım, M.D

Yavuz Selim Yıldırım, M.D Name- Surname: YAVUZ SELİM YILDIRIM Date of Birth: 09 / 10 / 1980 Place of Birth: Nationality: Profession: Kahramanmaraş Republic of Turkey (TR) M.D, Asist. Proffessor of Otolaryngology 1

Education: Medical Degree (M.D): İstanbul University, İstanbul Medical Faculty, İstanbul/Turkey (1999-2005) Residency Training: Ministery of Health, İstanbul Haseki Research and Training Hospital, Department of Otolaryngology, Istanbul/Turkey (2005-2010). Master Training (MBA): Beykent University, Institute of Social Sciences, Hospital and Health Institutions Management, İstanbul/Turkey (2007-2009). Asist. Professor: Bezmialem Vakıf University, Faculty of Medicine, Department of Otolaryngology Head And Neck Surgery, İstanbul, Turkey Board Certificates: Turkish Board Examination in Otorhinolaryngology - Head and Neck Surgery (29.12.2010) European Board Examination in Otorhinolaryngology - Head and Neck Surgery (18.11.2011) (Fellow of the European Board of ORL-HNS) (FEBORL-HNS) Language: Turkish and English Journal of Reviewing: The Laryngoscope Annals of Allergy, Asthma & Immunology Clinical Anatomy World Journal of Otorhinolaryngology Journal of Pediatric Infectious Diseases Address: Bezmialem Vakif University, Medical Faculty Otorhinolaryngology Department, Istanbul, Turkey E-posta: dryavuzselim@yahoo.com 2

Memberships: Turkish Ear Nose Throat and Head Neck Surgery Foundation (2006) İstanbul Physicians of Association (2006) Turkish Rhinologic Society (2008) The European Academy of Allergology and Clinical Immunology (2010) İstanbul Ear Nose Throat and Head Neck Surgery Specialisties Association (2010) European Rhinologic Society (2011) Academic and Clinical Interests Rhınology Rhinoplasty Functionel Endoscopic Sinus Surgery Skull Base Surgery Sinus Cancers Otology Cochlear Implant, Cholesteatoma Surgery, Stapedectomy, Semicircular Canal Dehissans Surgery Eustachian Tube Surgery Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=yıldırım+ys 1. Yildirim YS, Senturk E, Tugrul S, Ozturan O. Evaluation of the nasal contractility capacity in postmenopausal women. Rhinology. 2014 Dec;52(4):397-402. 3

2. Bilateral choanal atresia in an adult - management with mitomycin C and without stents: a case report. Aksoy F, Demirhan H, Yıldırım YS, Ozturan O. Cases J. 2009 Dec 11;2: 9307. 3. Total thyroidectomy in benign thyroid diseases. Veyseller B, Aksoy F, Demirhan H, Yıldırım YS, Ertaş B, Açıkalın RM, Kumral TL, Bayraktar GI. Kulak Burun Bogaz Ihtis Derg. 2009 Nov- Dec;19(6):299-303. 4. Advanced oxidation protein products as an oxidative stress marker in allergic rhinitis. Aksoy F, Demirhan H, Veyseller B, Yıldırım YS, Ozturan O, Basınoğlu F. Kulak Burun Bogaz Ihtis Derg. 2009 Nov-Dec;19(6):279-84. 5. A new oxidative stress marker in patients with nasal polyposis: advanced oxidation protein products (AOPP). Veyseller B, Aksoy E, Ertaş B, Keskin M, Ozturan O, Yıldırım YS, Bayraktar EG, Oztürk H. B-ENT. 2010;6(2):105-9. 6. Comparison of Radiofrequency and Monopolar Electrocautery Tonsillectomy. Aksoy F, Ozturan O, Veyseller B, Yıldırım YS, Demirhan H. J Laryngol Otol. 2010 Feb;124(2):180-4. Epub 2009 Nov 30. 7. Role of nasal muscles in nasal valve collapse. Aksoy F, Veyseller B, Yıldırım YS, Acar H, Demirhan H, Ozturan O. Otolaryngol Head Neck Surg. 2010 Mar;142(3):365-369. 8. Aksoy F, Dogan R, Ozturan O, Yildirim YS, Veyseller B, Yenigun A, Ozturk B. Betahistine Exacerbates Amikacin Ototoxicity. Ann Otol Rhinol Laryngol. 2014 Oct 30. Epub ahead of print]. 9. Eren SB, Kocak I, Dogan R, Ozturan O, Yildirim YS, Tugrul S. A comparison of the longterm results of crushing and crushing with intrinsic stripping techniques in concha bullosa surgery.int Forum Allergy Rhinol. 2014 Sep;4(9):753-8. 4

10. Use of N-butyl cyanoacrylate in nasal septoplasty; histopathological evaluation using rabbit nasal septum model. Aksoy F, Yılmaz F, Yıldırım YS, Gideroglu K, Tatar Z. J Laryngol Otol. 2010 Jul;124(7):753-8. Epub 2010 Mar 2. 11. Open functional neck dissection: surgical efficacy and electrophysiologic status of the neck and accessory nerve. Veyseller B, Aksoy F, Ozturan O, Acar H, Ertaş B, Bayraktar FG, Soylu E, Yıldırım YS. J Otolaryngol Head Neck Surg. 2010 Aug;39(4):403-9. 12. F. Aksoy, YS Yıldırım, U. Taskın, G. Bayraktar. Primary Nasal Tuberculosis; a case report. Tüberküloz ve Toraks Dergisi 2010; 58(3): 297-300. 13. Demirhan H, Aksoy F, Ozturan O, Yıldırım YS, Veyseller B. Medical treatment of adenoid hypertrophy with "fluticasone propionate nasal drops" Int J Pediatr Otorhinolaryngol. 2010 Jul;74(7):773-6. Epub 2010 Apr 28. 14. Patterns of cervical metastasis from squamous cell carcinoma of the head and neck. Aksoy F, Veyseller B, Binay O, Apuhan T, Yıldırım YS, Ozturan O. Kulak Burun Bogaz Ihtis Derg. 2010 Sep-Oct;20(5):249-54. 15. Aksoy F, Yıldırım YS, Ozturan O, Veyseller B, Cuhadaroğlu Ç. Eustachian Tube Function in Patients Receiving Continuous Positive Airway Pressure Treatment for Sleep Apnea Syndrome. J Otolaryngol Head Neck Surg. 2010 Dec;39(6):752-6. 16. Aksoy F, Yıldırım YS, Veyseller B, Ozturan O, Demirhan H. Midterm outcomes of outfracture of the inferior turbinate. Otolaryngol Head Neck Surg. 2010 Oct;143(4):579-84. 17. F. Aksoy, H. Demirhan, O. Özturan, YS Yıldırım. Allerjik Rinitte Subkutan Allerjen Sipesifik Immünoterapi. Turkiye Klinikleri J Med Sci. 2011;31(3):674-8. 5

18. Reduced olfactory bulb volume in total laryngectomy patients: A magnetic resonance imaging study. Bayram Veyseller, Fadlullah Aksoy, Yavuz Selim Yıldırım, Fatma Gülüm İvgin Bayraktar, Defne Gürbüz, Yıldıray Savaş, Orhan Özturan. Rhinology, 2011 Mar;49(1):112-6. 19. Çetinkaya E, Veyseller B, Yıldırım YS, Aksoy F, Özgül MA, Gençoğlu A, Altın S. The Value of Autofloresance bronchoscopy system. J Laryngol Otol. 2011: 125; 181-187. 2010 Nov 9:1-7. [Epub ahead of print] 20. Apuhan T, Yıldırım YS, Aksoy F, Balıkçı HH, Kaya MO. The Effect of Topical Cefepime Solution on Outer Hair Cell Function of Rats. Int. Adv. Otol. 2011; 7:(1) 49-54. 21. Apuhan T, Yıldırım YS, Ösaslan H. Is there any developmental relationship between mastoid pneumatization and adenoid tissue volume? International Journal of Pediatric Otorhinolaryngology. 2011;75(3):415-419. 22. Apuhan T, Yıldırım YS, Ösaslan H. The Developmental Relation between Adenoid Tissue and Paranasal Sinus Volumes in 3-Dimensional Computed Tomography Assessment. Otolaryngol Head Neck Surg. 2011 Jun;144(6):964-71. Epub 2011 Mar 1. 23. Apuhan T, Yıldırım YS, Aksoy F, Borçin Ö, Özturan O. The Effects of Desflurane and Sevoflurane on the Peri- and Postoperative Bleeding of Adenotonsillectomy Patients. Int J Pediatr Otorhinolaryngol. 2011 Jun;75(6):790-2. Epub 2011 Apr 1. 24. Demirhan H, Aksoy F, Ozturan O, Yıldırım YS, Veyseller B. Reply to Letter to the Editor: Is nasal saline just a placebo! Int J Pediatr Otorhinolaryngol. 2011;75: 884-5. Mar 21. [Epub ahead of print] 6

25. Apuhan T, Yıldırım YS, Gulcu N, Koçoglu H, Karagöz Y. The effect of prilocaine or levobupivacaine infiltration on pain during nasal packing removal. Otolaryngol Head Neck Surg. 2011 Sep;145(3):418-21. Epub 2011 May 25. 26. Yıldırım YS, Apuhan T, Kocoğlu E, Şimsek T, Kazaz H. High Sensitivity C - reactive protein Levels in Chronic Rhinosinusitis and Allergic Rhinitis. Kulak Burun Bogaz Ihtis Derg. 2011 Sep- Oct;21(5):266-9. doi: 10.5606/kbbihtisas.2011.039. 27. Veyseller B, Aksoy F, Yildirim YS, Karatas A, Ozturan O. Effect of recurrent laryngeal nerve identification technique in thyroidectomy on recurrent laryngeal nerve paralysis and hypoparathyroidism. Arch Otolaryngol Head Neck Surg. 2011 Sep;137(9):897-900. Epub 2011 Aug 15. 28. Apuhan T, Yıldırım YS, Eroglu F, Sipahier A.Effect of mitomycin C on endoscopic dacryocystorhinostomy. J Craniofac Surg. 2011 Nov;22(6):2057-9. 29. Yıldırım YS, Apuhan T, Ersözlü T, Bahar İ. Effects of Anesthesia on Patients Undergoing Surgery for Obstructive Sleep Apnea. J Anesthe Clinic Res. 2011. S7:001. doi:10.4172/2155-6148.s7-001 30. Apuhan T, Koçoğlu E, Yıldırım YS, Şimşek T, Kazaz H, Gök Ü. Effects of septoplasty on nasal and oropharyngeal microbial flora. African Journal of Microbiology Research Vol. 5(26), pp. 4583-4587, 16 November, 2011 31. Aksoy F, Yıldırım YS, Demirhan H, Ozturan O, Solakoglu S. Structural Characteristics of Septal Cartilage. J Laryngol Otol. 2012 Jan;126(1):38-42. Epub 2011 Sep 5. 7

32. Aksoy F, Demirhan H, Bayraktar GI, Yıldırım YS, Ozturan O, Gönüllü N, Sapmaz B. Effect of nasal mometasone furoate on the nasal and nasopharyngeal flora. Auris Nasus Larynx. 2012 Apr;39(2):180-5. Epub 2011 Sep 1. 33. Is Transnasal Endoscopic Examination Necessary Before and After Adenoidectomy? Yavuz Selim Yıldırım, Tayfun Apuhan, Fadlullah Aksoy, Bayram Veyseller and Orhan Özturan Indian Journal of Otolaryngology and Head & Neck Surgery, Online First, 5 January 2012. DOI: 10.1007/s12070-011-0467-4. 34. Veyseller B, Aksoy F, Yıldırım YS, Açıkalın RM, Gürbüz D, Özturan O. Olfactory dysfunction and olfactory bulb volume reduction in patients with leprosy. Indian Journal of Otolaryngology and Head & Neck Surgery.2012: 64; 261 265; DOI 10.1007/s12070-011-0284-9. 35. Yıldırım YS, Aksoy F, Ozturan O, Veyseller B, Demirhan H. Otoacoustic Emission Responses of the Cochlea to Acute and Total Ischemia. Indian Journal of Otolaryngology and Head & Neck Surgery.Published Online: 28 Agust 2012: DOI 10.1007/s12070-012-0561-2 36. Aksoy F, Yıldırım YS, Veyseller B, Demirhan H, Ozturan O. Serum Levels of Advanced Oxidation Protein Products in Response to Allergen Exposure in Allergic Rhinitis. Ear Nose Throat J. 2012 Aug;91(8):E32-5. 37. Veyseller B, Aksoy F, Ozturan O, Özücer B, Yıldırım YS, Gürbüz D. Reduced olfactory bulb volume and diminished olfactory function in total laryngectomy patients: A prospective longitudinal study. American Journal of Rhinology and Allergy.2012; 26(3):191-3. 38. Özkırış M, Kapusuz Z, Yıldırım YS, Saydam L. The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy. Int J Pediatr Otorhinolaryngol. 2012;76: 1027-29. 8

39. Apuhan T, Yıldırım YS, Şimşek T, Yılmaz F, Yılmaz F. Concha Bullosa Surgery and the Distribution of Human Olfactory Neuroepithelium. Eur Arch Otorhinolaryngol. 2013;270(3):953-7. doi: 10.1007/s00405-012-2173-6. Epub 2012 Sep 2. 40. Soylu E, Emir S, Yıldırım YS. Permanent Bilateral Sudden Sensorineural Hearing Loss after Acute Abdominal Surgery under General Anesthesia. Int. Adv. Otol. 2013; 9:(2) 279-282. 41. Özturan O, Aksoy F, Veyseller B, Apuhan T, Yıldırım YS. Severe Saddle Nose: Choices for Augmentation and Application of Accordion Technique Against Warping. Aesthetic Plast Surg. 2013 Feb;37(1):106-16. doi: 10.1007/s00266-012-0038-4. 42. Yıldırım YS, Apuhan T, Düzenli S, Arslan AO. Otosclerosis and vitamin D receptor gene polymorphism. Am J Otolaryngol. 2013 Apr 29. doi: S0196-0709(13)00079-3. 10.1016/j.amjoto.2013.03.016. [Epub ahead of print] 43. Yıldırım YS, Apuhan T, Koçoğlu E. Effects of intranasal phototherapy on nasal microbial flora in patients with allergic rhinitis. Iran J Allergy Asthma Immunol. 2013 Jul 13;12(3):281-6. 44. Yıldırım YS. Reply. Eur Arch Otorhinolaryngol. 2013 Jul;270(7):2171. doi: 10.1007/s00405-013-2512-2. 45. Soylu E, Soylu N, Yıldırım YS, Polat C, Sakallıoğlu O. The prevelance of psichiatric symptoms in preschool children with adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol. 2013 Jul;77(7):1094-8. doi: 10.1016/j.ijporl.2013.04.005. Epub 2013 May 2. 46. Ersözlü T, Yıldırım YS. Early extrusion and infection of ventilation tubes of otitis media with effusion; alpha-mannosidosis: A report of two siblings. International Journal of Pediatric Otorhinolaryngology Extra. 27 June 2013. http://dx.doi.org/10.1016/j.pedex.2013.05.001. 9

47. Hakyemez HA, Veyseller B, Ozer F, Ozben S, Bayraktar GI, Gurbuz D, Cetin S, Yildirim YS. Relationship of olfactory function with olfactory bulbus volume, disease duration and Unified Parkinson's disease rating scale scores in patients with early stage of idiopathic Parkinson's disease. J Clin Neurosci. 2013;20(10):1469-70. doi: 10.1016/j.jocn.2012.11.017. 48. Dogan R, Aksoy F, Yıldırım YS, Ozturan O. Tension pneumocephalus: an extremely small defect leading to an extremely serious problem. Am J Otolaryngol. 2013;34(6):749-52. doi: 10.1016/j.amjoto.2013.07.011. 49. Soylu E, Soylu N, Yıldırım YS, Sakallıoğlu Ö, Polat C, Orhan I. Psychiatric disorders and symptoms severity in patients with adenotonsillar hypertrophy before and after adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 2013;77(10):1775-81. doi: 10.1016/j.ijporl.2013.08.020. 50. Ozaydin A, Akbas F, Aksoy F, Yildirim YS, Demirhan H, Karakurt F, Koc A, Onaran I, Sultuybek GK. Investigation of Poly (ADP-Ribose) Polymerase-1 Genetic Variants as a Possible Risk for Allergic Rhinitis. Genet Test Mol Biomarkers. 2013 Nov 1. [Epub ahead of print] 51. Ersözlü T, Yıldırım YS, Sarıca S. Comparison of Pediatric and Adult Tonsillectomies Performed by Thermal Welding System. International Journal of Otolaryngology. Accepted 7 October 2013 10