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Abstract Directed by instructional cards, students kinesthetically model cell communication by acting as components in a cell signaling pathway. Logistics Time Required Class Time: 30 minutes Learning Objectives Cell communication is a multistep process. Cells communicate via signaling pathways made of interacting components. Components of cell signaling pathways sometimes change shape as a result of their interaction (conformational change). Prep Time: 10 minutes Materials Classroom set of Cell Communication Cards (included), Overhead transparency and projector Prior Knowledge Needed None Appropriate For: Primary Intermediate Secondary College 2008 University of Utah This activity was downloaded from: /teachers

Classroom Implementation Activity instructions: Create a space in which students can move freely. Form groups of six students each. (You may have multiple groups in one class, or choose one group to demonstrate Explain the rules of the activity:»»each person will be given a card.»»do not let others what know what your card says. Quantities Per Group of 6»» When prompted, follow the instructions on the card to create a cell signaling pathway. One set of Cell Communication Cards (page 3) An overhead transparency (page 4) summarizing the steps of the cell signaling pathway. Distribute one set of Cell Communication Cards to each group of six, and ask the students in each group to chose a card from their set. Once every student has a card, prompt the groups to begin by following instruction #1 on their card. Next, instruct your students to follow instruction #2 on their card. When each group is finished, show the whole class an overhead transparency of page 4, summarizing the cell signaling steps the students just demonstrated. Discuss the activity and how it models signaling pathways in the cell. Discussion Points: What happened? How did you recognize where to go? How does this model cell communication? What effect did joining the pathway have on you? (Looking for something to indicate conformational change.) What problems did you encounter? What would have happened if someone didn t do their job (follow instructions) or weren t there? 2008 University of Utah This activity was downloaded from: /teachers 1

Standards U.S. National Science Education Standards Grades 9-12: Life Science Content Standard C: Life Science - The Cell; Cells have particular structures that underlie their functions. Every cell is surrounded by a membrane that separates it from the outside world. Inside the cell is a concentrated mixture of thousands of different molecules which form a variety of specialized structures that carry out such cell functions as energy production, transport of molecules, waste disposal, synthesis of new molecules, and the storage of genetic material. B. AAAS Benchmarks for Science Literacy: Grades 9-12 The Living Environment Cells»»Within every cell are specialized parts for the transport of materials, energy transfer, protein building, waste disposal, information feedback, and even movement. In addition, most cells in multicellular organisms perform some special functions that others do not. Credits and much more! Christian Davies, Brockbank Junior High, Sandy, UT Barbara Eagan, Beavercreek High, Beavercreek, OH Mary Hoelscher, Sobriety High, Minneapolis, MN Chris Kuka, Bend Senior High, Bend, OR Molly Malone, Genetic Science Learning Center Harmony Starr, Genetic Science Learning Center (illustrations) Funding Why Log-In On Our Website? Logging in as a teacher on the Learn.Genetics website has its benefits. You ll get exclusive access to great resources just for you! Get links to resources for this and other Print-and- Go activities. Access extra media materials for this module. Download classroom-ready presentations and graphics. Tips for using activities with online materials. Funding for this module was provided by a Science Education Partnership Award from the National Center for Research Resources, a component of the National Institutes of Health. 2008 University of Utah This activity was downloaded from: /teachers 2

1. Remain standing as you are. 2. Find someone with their hand in the air and grab their hand. 1. Put your hand in the air until someone grabs your hand. 2. Find someone with their hands on their head and lean them back. 1. Find the person with outstretched arms and stand back to back with them. 2. Put your hands on your head. 1. Stretch your arms out in front of you. 1. Put your foot up in the air. 1. Close your eyes and put your head down. 2. Grab the person with their foot in the air when leaned forward. 2. When you get grabbed, touch the shoulder of the person with their eyes closed 2. Run in place when touched on your shoulder. 2008 University of Utah This activity was downloaded from: /teachers 3

BUMP ACTIVATE! BUMP 2008 University of Utah Permission granted for classroom use. ACTIVATE!