Margaret L. Longacre, PhD Director, Research Cancer Support Community. March 4, 2016

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Innovation in Developing Evidence-Based Programs that Identify and Address the Social and Emotional Needs of Cancer Caregivers: Distress Screening and Referral for Caregivers Margaret L. Longacre, PhD Director, Research Cancer Support Community March 4, 2016 1

Cancer Support Community 2

Presentation Objectives Why distress screening and referral for caregivers matters Overview of the Cancer Support Community s (CSC) history on caregiving Describe the development of CSC s distress screening and referral program for caregivers Planning phase Research phases Findings Challenges and opportunities in engaging diversity of caregivers A call toward collaboration 3

Why distress screening and referral for caregivers. Family caregivers are an indispensable component of our national health care resources. The economic value of informal care was estimated at $470 billion in 2013. Caring for cancer patients is accompanied by emotional distress. Psychosocial distress is associated with poorer outcomes for caregivers and patients. While caregiver burden measures exist, there is a lack of validated distress screening and referral programs for cancer caregivers. References: Sherwood et al., 2008; Northouse et al., 2012; Litzelman & Yabroff, 2015; Mittleman et al., 1996; Reinhard et al., 2015. 4

Potential implications of caregiver well-being? Caregiver Immune response Risk for chronic disease Patient Emotional Response Society Overall cost of care Emotional Response References: Sherwood et al., 2008; Northouse et al., 2012; Litzelman & Yabroff, 2015; Mittleman et al., 1996.

A History of Serving Caregivers at CSC 1983: Recognized the vital role of caregivers Caregiver survey with NCCS Key findings: 1) Patients thought their caregivers were doing fine, while caregivers reported being under distress; 2) caregivers expressed random acts of kindness The CSC Affiliate voice to screen caregivers Currently, 44% of CSC Affiliate care is to caregivers A united strategy for screening patients/survivors and their caregivers CancerSupportSource (CSS) program assesses patients levels of distress and need, and then helps refer them for help and follow-up care. 6

Proof of Concept: CancerSupportSource-Caregiver Can we assess concerns and distress among caregivers, refer them for services or information and follow up? Is CancerSupportSource a feasible foundation? What are appropriate comparison scales? Based on advisor input, the selected measures captured the range of the caregiver experience The Center for Epidemiologic Studies Depression Scale (CES-D) SF-12 Distress Thermometer (DT) Zarit Caregiver Burden measure (short form) Caregiver Reaction Assessment 7

CSS-Caregiver Study Objectives To identify problems primary cancer caregivers report, and which are most distressing To learn which problems relate to cancer caregivers by age, SES, race, gender, and cancer type To validate CancerSupportSource for caregivers using gold standard instruments 8

Study Trajectory Phase II Scale Comparison Phase III Implementation research Phase I Focus Groups Cognitive Interviews CSS-Caregiver Planning 9

Phase I: Focus Groups Objectives To evaluate how well CancerSupportSource (i.e., patient version) addresses the needs of cancer caregivers and make changes based on their recommendations. To receive caregiver input on what changes need to be made to the screening tool so that it is appropriate for the caregiver population. Conducted 3 focus groups at CSC Affiliates with 24 total caregivers Cancer Support Community Delaware: 8 Caregivers Gilda s Club Louisville: 11 caregivers Gilda s Club Chicago : 5 caregivers 10

25-Item CSS-Patient Version Used to Guide Focus Groups (Based upon IOM, 2007) Information about cancer and its treatment and services e.g., Communicating with your doctor Help in coping with emotions e.g., Feeling sad or depressed Help in managing the illness e.g., Eating and nutrition Assistance in changing behaviors to minimize the impact of the disease e.g., Recent weight change Material and/or logistical support e.g., Transportation to treatment and appointments Help in managing disruptions in work, school, family e.g., Changes or disruptions in work and/or school Financial advice and/or assistance e.g., Health insurance or money worries 11

Focus Group: Primary Learnings Led to clarifying language in directions Led to clarifying language in items Managing and/or keeping up with my health care needs Communicating with the patient s health care team Separated out items Changes or disruptions in my home life, work or school (now 2 items) New caregiver specific items, such as: feeling guilty Feeling unappreciated Maintaining appearances or keeping it all together in front of others Feeling that I m always on 12

CSS-Patient Repurposed for Caregiving Care for self e.g., Today how CONCERNED are you about the following for YOURSELF?...eating and nutrition Management of caregiving roles and responsibilities e.g., Today, how CONCERNED are YOU about the following caregiving roles or tasks (i.e., ways you help)?... Talking with the patient s doctors and health care team Experience of witnessing change or decline of loved one e.g., Today, how CONCERNED are YOU about the following for THE PERSON YOU ARE CARING FOR?... The patient s pain and/or physical discomfort 13

Phase I: Cognitive Interviews Objectives A think aloud process for caregivers to provide thoughts or opinions about each question. 10 phone interviews of caregivers identified via CSC affiliates. 3 interviewers with audio-recording and transcription Based upon a cognitive interviewing guide developing based on Using Cognitive Interviews to Refine a Questionnaire Garcia (2007) 14

Cognitive Interview: Examples of Learning Caregivers validated the items Most caregivers understood and supported items At times, caregivers reported a disconnect with a phrase or word: Feeling sad or depressed: Felt bad bummed out worried but depressed is like being on meds If there was critical mass, then we made changes: Communicating with my healthcare team: If I get sick what happens - a little redundant. 15

Table 1. Focus Group and Cognitive Interview Participant Demographics (n=34) Frequency (n) % Female 22 65% Non-Hispanic white 31 91% Spouse 25 73% Age (n=33) 26-38 42-55 48-64 65 or older Household Income* (n=24) < $40,000 $40,000-$79,999 $80,000 or above Prefer not to share Residence* (n=24) Urban Suburban Rural 6 12 6 9 5 7 8 4 10 11 3 18% 36% 18% 27% 21% 29% 33% 17% 41% 46% 12% *Focus group only 16

Phase II: CSS-Caregivers Validation 10 Affiliate Recruitment Sites for Validation Study o GC Chicago o GC Quad Cities o CSC Greater St. Louis o GC Kansas City o CSC Central Ohio o GC Madison o GC Louisville o CSC Delaware o CSC San Francisco Bay Area o CSC Greater Philadelphia Outreach and registration via affiliates Web-based platform delivery (link via email following registration) Paper version option Enrollment goal of 250-300 caregivers Current enrollment = 221 17

Table 2. Phase II Sample Characteristics Frequency (n) % Gender (n=211) Male Female 68 143 32.2% 67.8% Race/Ethnicity (n=197) Asian Black Hispanic Non-Hispanic White Prefer not to share Household Income (n=209) < $40,000 $40,000-$79,999 $80,000 or above Prefer not to share Region (n=210) Urban Suburban Rural 6 5 10 171 5 34 47 80 48 46 135 29 3% 2.5% 5.1% 86.8% 2.5% 16% 22.2% 37.7% 22.6% 21.7% 63.7% 13.7% Age (n=206) Mean = 53.62 (SD: 113.86; range: 22-83) Age Categorical 22-39 40-54 55-64 >65 44 58 56 48 21.6% 28.2% 27.1% 23.1% 18

Patient s Cancer Type (n=209) 9% 8% 8% 35% Other Breast Blood Lung 15% Brain Gynecologic 24% 19

Table 3. Caregiving Characteristics Frequency (n) % Care recipient is: (n=214) Spouse Parent/In-law Active Treatment in Past 2 Years: (n=212) Yes No Not applicable Hours of care provided/week: (n=210) <20 hours 21-80 hours >80 hours 126 41 173 27 12 137 46 27 58.9% 19.2% 81.6% 12.7% 5.7% 65.2% 21.8% 12.8% 20

Graph 1. Caregiver Self-Reported Distress (n=214) 60 56.5 50 40 % 30 25.7 20 17.3 10 0 0-3 4-6 7-10 (Distress Thermometer: 0; not at all -10; extreme distress) 21

Table 1. CSS-Caregiver top concerns, moderate, serious or very serious concern (n=214) 80% 70% 60% 50% 40% 30% 20% 10% 0% 71% 58% 57% 56% 53% 53% 50% 49% 49% 48% 22

Table 2. CSS-Caregiver top concerns, serious or very serious concern (n=214) 45% 40% 35% 30% 25% 20% 15% 10% 5% 0% 38% 30% 29% 27% 27% 26% 26% 25% 22% 21% 23

Table 2. CSS-Caregiver top items for which caregivers requested talking to staff (n=214) 18.0% 16.0% 14.0% 12.0% 10.0% 8.0% 6.0% 4.0% 2.0% 0.0% 15.4% Feeling sad or depressed 14.7% 14.1% Worrying about Changes in the the future and patient's mood what lies ahead and/or behavior 12.6% 11.9% 11.9% Relationship Feeling nervous problems with or afraid the person for whom I am caring Changes or disruptions in my home life 24

Table 2. CSS-Caregiver top items for which additional information was requested (n=214) 29.0% 28.0% 27.0% 27.9% 27.1% 26.0% 25.5% 25.0% 24.7% 24.5% 24.5% 24.0% 23.0% 22.0% Worrying about the future and what lies ahead The patient's eating and nutrition Gaining information about how to provide care Changes or disruptions in my home life Changes in the Changes in the patient's mood patient's and/or memory behavior and/or thinking 25

Next Steps Challenges and opportunities in engaging diversity of caregivers Explore Differences Race/ethnicity Age (young adult caregivers) Region (rural caregivers) Strategies Paper version Engaging community sites with greater diversity CSC Greater Philadelphia at Temple University CSC Whitman-Walker Health Clinic, Washington DC Making web-based platforms accessible via phones 26

Thank you To the many patients, survivors and caregivers who have contributed to the vision of improving cancer care for all those impacted by cancer To the many colleagues and advisors who contributed their time and expertise to advance care This research was funded by Amgen Oncology 27