GE Healthcare Life Sciences

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To whom it may concern Regarding: Halal and Kosher in chromatography media Halal Halal refers to products permitted under Islamic dietary law. Internationally recognized organizations certify that ingredients, production and packing comply with the Islamic dietary guidelines. Kosher Kosher refers to products permitted under Jewish dietary law. The responsible rabbinical authority certifies that ingredients, production, and packing comply with their religious requirements. It is hereby stated that: GE Healthcare bioprocess chromatography media products have not been certified for Halal or Kosher. Signature: Date: 17 September 2014 This document has been electronically produced and is valid without a signature Name: Ann-Christine Häggqvist Title: Regulatory Support Manager The information herein is provided to the best of our knowledge and belief, based on the information we have been given and the information available to us at the time that this document was issued. The information may change as additional facts come to light, or as the circumstances warrant. Your use hereof is hence at your own risk and does not relieve you of your own responsibility for checking the suitability of our products for your intended use. Page 1 of 5

Attachment List of all products concerned Product 6-AKS Sepharose 4 Fast Flow AH Sepharose 4B Amino Sepharose 6 Fast Flow ANX Sepharose 4 Fast Flow ANX Sepharose 4 Fast Flow (High Sub) AVB Sepharose High Performance Benzamidine Sepharose 4 Fast Flow (High Sub) Benzamidine Sepharose 4 Fast Flow (Low Sub) Benzamidine Sepharose 6B Blue Sepharose 6 Fast Flow Blue Sepharose CL-6B Butyl Sepharose 4 Fast Flow Butyl Sepharose 4B Butyl Sepharose High Performance Butyl Sepharose High Performance (High Sub) Butyl-S Sepharose 6 Fast Flow Capto adhere Capto adhere ImpRes Capto Blue High Sub Capto Butyl Capto Butyl ImpRes Capto Core 700 Capto DEAE Capto DeVirS Capto Heparin Capto L Capto MMC Capto MMC ImpRes Capto Octyl Capto Phenyl High Sub Capto Phenyl ImpRes Capto Q Capto Q ImpRes Capto S Capto SP ImpRes Capto Blue Code number 173100XX* 170470XX 173092XX 171286XX 171287XX 284112XX 175123XX 284108XX 170568XX 170948XX 170962XX 170980XX 170960XX 175432XX 175433XX 170978XX 175444XX 173715XX 175452XX 175459XX 173719XX 175481XX 175443XX 175466XX 175462XX 175478XX 175317XX 173716XX 175465XX 175451XX 175484XX 175316XX 175470XX 175441XX 175468XX 175448XX Page 2 of 5

Chelating Sepharose Big Beads 175272XX Chelating Sepharose Fast Flow 170575XX CM Sephadex C-25 170210XX CM Sephadex C-50 170220XX CM Sepharose Fast Flow 170719XX CM Sepharose High Performance 171277XX CNBr Activated Sepharose 4 Fast Flow 170981XX CNBr Activated Sepharose 4B 170430XX Con A Sepharose 4B 170440XX DEAE Sephacel 170500XX DEAE Sephadex A-25 170170XX DEAE Sephadex A-50 170180XX DEAE Sephadex A-50 Special grade 170181XX DEAE Sepharose CL-6B 170710XX DEAE Sepharose Fast Flow 170709XX ECH Lysine Sepharose 4 Fast Flow 170902XX ECH Sepharose 4B 170571XX Gelatin Sepharose 4 Fast Flow 170976XX Gelatin Sepharose 4B 170956XX Glutathione Sepharose 4B 170756XX Heparin Sepharose 6 Fast Flow 170998XX Heparin Sepharose CL-6B 170467XX, 170552XX IgSelect 284113XX IMAC Sepharose 6 Fast Flow 170921XX KappaSelect 175458XX LambdaFabSelect 175482XX Lentil Lectin Sepharose 4B 170444XX Lysine Sepharose 4B 170690XX MabSelect SuRe 175438XX MabSelect SuRe LX 175474XX MabSelect Xtra 175269XX MabSelect 175199XX MacroCap Q 175469XX MacroCap SP 175440XX Mono Q 28928730, 28951098 28937625 Mono S 90100428, 90100243 28918829, 90100332 NHS-activated Sepharose 4 Fast Flow 170906XX Ni Sepharose 6 Fast Flow 175318XX Ni Sepharose High Performance 175268XX nprotein A Sepharose 4 Fast Flow 175280XX Octyl Sepharose 4 Fast Flow 170946XX Octyl Sepharose CL-4B 170790XX Phenyl Sepharose 6 Fast flow (High Sub) 170973XX Phenyl Sepharose 6 Fast flow (Low Sub) 170965XX Phenyl Sepharose Big Beads 175098XX Phenyl Sepharose CL-4B 170810XX Phenyl Sepharose High Performance 171082XX Page 3 of 5

PlasmidSelect 175257XX PlasmidSelect Xtra 284024XX Plasminogen Removal Gel 284109XX Protein A Sepharose 4 Fast Flow 170974XX Protein A Sepharose 6 Fast Flow 170970XX Protein A Sepharose CL-4B 170963XX, 170780XX Protein G Sepharose 4 Fast Flow 170618XX Protein G Sepharose High Performance 90100253, 90100138 90100020, 90100093 Q Sepharose High Performance 171014XX Q Sepharose Big Beads 170989XX Q Sepharose Fast Flow 170510XX Q Sepharose XL 175072XX QAE Sephadex A-25 170190XX QAE Sephadex A-50 170200XX rmp Protein A Sepharose Fast Flow 175138XX rprotein A Sepharose Fast Flow 171279XX S Sepharose Fast Flow 170511XX Sephacryl S-100 HR 170612XX Sephacryl S-1000 Superfine 170476XX Sephacryl S-200 SF 170871XX Sephacryl S-300 HR 170599XX Sephacryl S-400 HR 170609XX Sephacryl S-500 HR 170613XX Sephacryl S-200 HR 170584XX Sephadex G-10 170010XX Sephadex G-100 170060XX Sephadex G-100 SF 170061XX Sephadex G-15 170020XX Sephadex G-25 Coarse 170034XX Sephadex G-25 Fine 170032XX Sephadex G-25 Medium 170033XX Sephadex G-25 Superfine 170031XX Sephadex G-50 Coarse 170044XX Sephadex G-50 Fine 170042XX Sephadex G-50 Medium 170043XX Sephadex G-50 Superfine 170041XX Sephadex G-75 170050XX Sephadex G-75 Superfine 170051XX Sephadex LH-20 170090XX Sepharose 2B 170130XX Sepharose 4 Fast Flow 170149XX Sepharose 4B 170120XX Sepharose 6 Fast Flow 170159XX Sepharose 6B 170110XX Sepharose CL-2B 170140XX Sepharose CL-4B 170150XX Sepharose CL-6B 170160XX SOURCE 15 S 170944XX Page 4 of 5

SOURCE 15ETH SOURCE 15ISO SOURCE 15PHE SOURCE 15RPC SOURCE 30 RPC SOURCE 30Q SOURCE 30S SOURCE 15 Q SP Sepharose Big Beads SP Sepharose Fast Flow SP Sepharose High Performance SP Sepharose XL STREAMLINE Chelating STREAMLINE DEAE STREAMLINE PHENYL STREAMLINE Q XL STREAMLINE QUARTZ Base matrix STREAMLINE SP STREAMLINE SP XL STREAMLINE Q XL Virus licensed Suderdex 75 Prep Grade Superdex 30 Prep Grade Superdex 200 Prep Grade Superose 12 Prep Grade Superose 6 Prep Grade VIIISelect VIISelect 170146XX 170148XX 170147XX 170727XX 175120XX 171275XX 171273XX 170947XX 170657XX 170729XX 171087XX 175073XX 171280XX 170994XX 175121XX 175075XX 175104XX 170993XX 175076XX 175439XX 171044XX 170905XX 171043XX 170536XX 170489XX 175450XX 175477XX *) xx refers to all pack sizes Page 5 of 5