Regulatory Requirements for Product / Quality System Assessments and Audits How to Prepare?



Similar documents
QUALITY MANAGEMENT SYSTEM REQUIREMENTS General Requirements. Documentation Requirements. General. Quality Manual. Control of Documents

Preparing for Unannounced Inspections from Notified Bodies

Frequently Asked Questions. Unannounced audits for manufacturers of CE-marked medical devices. 720 DM a Rev /10/02

Schweppes Australia Head Office Level 5, 111 Cecil Street South Melbourne Victoria

ONTIC UK SUPPLIER QUALITY SURVEY

Quality Management System Manual

UNCONTROLLED COPY FOR REFERENCE ONLY

ISO 9001:2000 AUDIT CHECKLIST

AS9100 Quality Manual

ISO 9001:2008 Audit Checklist

BSI Unannounced Audits

RTP s NUCLEAR QUALITY ASSURANCE PROGRAM

Company Quality Manual Document No. QM Rev 0. 0 John Rickey Initial Release. Controlled Copy Stamp. authorized signature

Comparison between FDA QSR and ISO 13485

ISO 9001:2000 Gap Analysis Checklist

International Projects. Safety and Quality Assured. Supply chain and integrity services for international projects.

DNV GL Assessment Checklist ISO 9001:2015

Cartel Electronics. AS 9100 Quality Systems Manual

QUALITY MANAGEMENT SYSTEM Corporate

EMS Example Example EMS Audit Procedure

23. The quality management system

NABL NATIONAL ACCREDITATION

ISO 9001 : 2000 Quality Management Systems Requirements

ISO 9001 (2000) QUALITY MANAGEMENT SYSTEM ASSESSMENT REPORT SUPPLIER/ SUBCONTRACTOR

Micro Plastics, Inc. Quality Manual

The President of Inductors Inc. is the senior executive responsible for operations.

Row Manufacturing Inc. Quality Manual ISO 9001:2008

Correlation matrices between 9100:2009 and 9100:2016

CENTRIS CONSULTING. Quality Control Manual

BASE CONSTRUCTION INC

Quality Manual ALABAMA RESEARCH & DEVELOPMENT. This Quality Manual complies with the Requirements of ISO 9001:2008.

QW Enterprises, LLP. Quality Manual

Guideline on good pharmacovigilance practices (GVP)

Supplier quality guideline. VOSS Automotive Group Issue Rev00

ALL PRODUCTS MFG & SUPPLY

Quality Management System General

Quality management systems

MSC Group Chain of Custody (CoC) Guidance for Non-Reduced Risk Groups

QUALITY MANUAL ISO 9001:2015

NIST HANDBOOK CHECKLIST CONSTRUCTION MATERIALS TESTING

Summary of Requirements for ISO 14001:2004 February 24, 2005

How DCMA Helps To Ensure Good Measurements

FINAL DOCUMENT. Guidelines for Regulatory Auditing of Quality Management Systems of Medical Device Manufacturers Part 1: General Requirements

Comparison ISO/TS (1999) to VDA 6.1 (1998)

ISO 9001 Quality Systems Manual

Table of Contents 1. SCOPE APPLICABLE DOCUMENTS TERMS AND DEFINITIONS QUALITY MANAGEMENT SYSTEM...4-8

Changes to Medical Device Regulations

SUPPLIER QUALITY MANAGEMENT SYSTEM QUESTIONNAIRE

Quality Management System

New Program Quality Requirements for Suppliers (NPQR) For Limited Manufacturing of Components and/or Processes for Engineering Certification

QUALITY MANUAL REVISION RECORD

ISO-9001:2000 Quality Management Systems

API Q2 Specification for Quality Management System Requirements for Service Supply Organizations for the Petroleum and Natural Gas Industries

Quality Manual. This Quality Manual complies with the Requirements of ISO 9001:2008 and ISO/IEC , Explosive Atmospheres - Edition 1.

Copyright, Language, and Version Notice The official language of this [Certification Protocol] is English. The current version of the [Certification

SQ 901 Version D. Railway Application Quality Specification REQUIREMENTS FOR THE QUALITY MANAGEMENT SYSTEM AND QUALITY PLAN

Certification Process Requirements

QUALITY MANUAL 3 KENDRICK ROAD WAREHAM, MA FAX

ISO 9001 : 2008 QUALITY MANAGEMENT SYSTEM AUDIT CHECK LIST INTRODUCTION

Improving global standard to be a key driver of innovation. Colin MacNee. 2012, 2013, 2014 Duncan MacNee Limited.

Summary of GE Healthcare's Quality Management System (QMS) Covering BioProcess chromatography media, equipment, software, and spare parts

This Business Management System Manual is based on ISO 9001:2008 requirements

AS 9100 Rev C Quality Management System Manual. B&A Engineering Systems, Inc Business Park Drive, Suite A-1 Costa Mesa, CA 92626

File:Quality-Management Manual-V2

Description of the certification procedure MS - ISO 9001, MS - ISO 14001, MS - ISO/TS and MS OHSAS and MS ISO 50001

Guidance from the Group of Notified Bodies for the Construction Products Directive 89/106/EEC. GNB-CPD position paper from SG17 - EN :2009

ORACLE CONSULTING GROUP

AEROSPACE STANDARD. Quality Management Systems - Requirements for Aviation, Space and Defense Organizations RATIONALE

Internal Quality Management System Audit Checklist (ISO9001:2015) Q# ISO 9001:2015 Clause Audit Question Audit Evidence 4 Context of the Organization

GMP Issues for Start-Ups, quality in the supply chain and role of the Qualified Person (QP)

Translation Service Provider according to ISO 17100

AVNET Logistics & EM Americas. Quality Manual

MINIMUM AUTOMOTIVE QUALITY MANAGEMENT SYSTEM REQUIREMENTS FOR SUB-TIER SUPPLIERS

ISO 9000 Introduction and Support Package: Guidance on the Documentation Requirements of ISO 9001:2008

Konformitätsbewertung 3.9 B 17. Guidance for Notified Bodies auditing suppliers to medical device manufacturers

QUALITY MANUAL ISO Quality Management System

AS9100:2016 Transition Guide

Rules for the certification of event sustainability management system

Revision Date Author Description of change Jun13 Mark Benton Removed Admin. Manager from approval

ISO 9001:2015 Internal Audit Checklist

Surgi Manufacturing Quality Manual

NORTH AMERICA OPERATIONS. (Fairmont and Montreal Facilities) QUALITY MANUAL. Prepared to comply with the requirements of ISO 9001:2008

Rev: Issue 4 Rev 4 Quality Manual AOP0101 Date: 10/07/13. Quality Manual. CBT Technology, Inc. 358 North Street Randolph, MA 02368

Helical Products Co., Inc.

When printed the document is for reference only and is considered uncontrolled - refer to the Document Control System for the most current version

Guideline on good pharmacovigilance practices (GVP)

Rules for the certification of asset management systems

Audits must be conducted with due concern for employee safety and environmental protection.

Quality Management System Manual

ISO 9001:2008 QUALITY MANUAL. Revision B

Example of a food company quality

QUALITY MANAGEMENT SYSTEM (QMS) MANUAL

Software Quality Subcontractor Survey Questionnaire INSTRUCTIONS FOR PURCHASE ORDER ATTACHMENT Q-201

ISO 9001: 2008 Construction Quality Management System Sample - Selected pages (not a complete plan)

MEDFORD FABRICATION CSC, INC. Quality System Manual. Date of issue: 03/25/2010 Revision : F

GLUTEN-FREE CERTIFICATION PROGRAM

RSPO Supply Chain Certification Systems

Transcription:

Regulatory Requirements for Product / Quality System Assessments and Audits How to Prepare? Hans-Heiner Junker Division Manager, Certification Body TÜV SÜD Product Service GmbH Folie 1

Unannounced Audits What is the focus of an Unannounced Audit? Document 2013/473/EU makes it clear. There are two main parts: Quality System Part Product Part Overall: an UAA is certainly more product focused then the regular audits in the past Product focus means: the notified body will select a product from the product portfolio, and most actions will be linked to this selected product Folie 2

What Actions? the notified bodies should check a recently produced adequate sample, preferably a device taken from the ongoing manufacturing process, for its conformity with the technical documentation and with legal requirements. The check of the conformity of the device should include the verification of the traceability of all critical components and materials and of the manufacturer s traceability system. include a file review and, if necessary in order to establish the conformity, a test of the device Folie 3

Addition 1 Notified bodies in charge of verifying the quality system of the manufacturer should, verify whether the manufacturing activity ongoing at the time of the unannounced audit is in line with the manufacturer s documentation relevant for the manufacturing activity and that both are in conformity with legal requirements. in addition, these notified bodies should check in more detail at least two critical processes such as design control, establishment of material specifications, purchasing and control of incoming material or components, assembling, sterilisation, batch-release, packaging, or product quality control. Amongst the suitable critical processes, notified bodies should select one which has a high likelihood of non-conformity and one which is particularly safety relevant. Folie 4

Addition 2 Notified bodies in charge of product assessment should: sample devices belonging to at least three different device types and, where the manufacturer produces more than 99 device types, devices belonging to at least every hundredth type at the end of the production chain or in the manufacturer s warehouse with a view of testing the conformity of the device types These samples should be tested by the notified bodies or by qualified personnel under their observation on their own premises, or on the manufacturer s premises, or on the premises of the manufacturer s critical subcontractor or crucial supplier or in external laboratories. Sampling criteria and testing procedures should be defined in advance. if a sampling in the manufacturer s premises is not possible, notified bodies should take samples from the market or perform testing on a device installed at a customer location Folie 5

Now: what to expect? Visit is not announced Challenges are but not limited to: no adjustment with audit team, no audit plan in advance important, critical employees may not be around access to documentation may not be easy people are engaged in normal work scheduled work needs to be postponed, rescheduled you may be in the middle of important preparation for the next exhibition Folie 6

How to prepare? What can be done prior to such an unannounced audit? protocols must be available Who needs to be informed? What supporters must be called in? Who is the first person to be in contact with the audit team? Any specific escalation process? Upper management? Access to production and warehouse must be granted (safety issue?) Auditors need to be accompanied, expect two or more auditors Be prepared to show test plans, test protocols Be prepared to show some physical testing (incoming, in-process, final; type testing) Test equipment may need to be freed from routine work Folie 7

How to prepare? What can be done prior to such an unannounced audit? Have the contracts with suppliers and subcontractors updated Have the qualification protocols of suppliers and subcontractors ready and up-to-date Perform internal product audits in addition to process audits Perform internal Technical File audits in addition to process audits Keep traceability records up-to-date Have the costs of the UAA in the budget Raise awareness in your company Conduct mock audit as unannounced audit Folie 8

Effort/Stress Effort and Stress in Relation to Audits Year Folie 9

Effort and Stress in Relation to Audits Audit Folie 10

Effort and Stress in Relation to Audits Audit Folie 11

Effort and Stress in Relation to Audits Audit Folie 12

Effort and Stress in Relation to Audits Do you know this? Audit Folie 13

Effort and Stress in Relation to Audits Folie 14

Effort/Stress Effort and Stress in Relation to Audits Ideal Situation Year Folie 15

Effort/Stress Effort and Stress in Relation to Audits Could this be real? Year Folie 16

Be prepared at all times Maintain compliance of your quality system with regulatory requirements and maintain compliance with your quality system Keep your products and their documentation up-to-date Continously monitor the performance of your device Continously monitor the performance of your subcontractors Make sure that you know what changes are significant for you, your quality system or your products have they under your control Folie 17

Good Luck Folie 18