Genetic Testing Common ICD-10-CM s The ICD-10-CM codes listed below are commonly associated with genetic testing, including cytogenetics, biochemical, and molecular genetics, were selected based on the reporting frequency to LabCorp of their ICD-9-CM counterparts. descriptions were taken from the official code set issued by the US Department of Health and Human Services and are scheduled to be implemented October 1, 2015. Depending on the nature of your practice, this list may be a useful reference tool; however, it is not a complete list. Please refer to an ICD-10-CM manual for a complete listing. The ultimate responsibility for the provision of correct diagnosis code(s) is with the ordering physician. The ordering physician must always determine, for the specific date of service, the appropriate diagnosis code(s) based on the patient s signs and symptoms. ICD-CM codes in effect at the time of service are required by third-party payors to confirm the medical necessity of the test(s) and/or profile(s) ordered. Physicians are asked to submit all medically appropriate ICD-CM codes when ordering laboratory testing. LabCorp s provision of this information as a customer service does not suggest and is not meant to suggest that any of these codes should or should not be used on any given occasion. LabCorp makes no recommendation regarding the use of any particular diagnosis code(s). information should be reflected in the patient s medical record. (sign or symptom) R76.9 Abnormal immunological finding in serum, unspecified R94.5 Abnormal results of liver function studies D68.51 Activated protein C resistance R1Ø.Ø Acute abdomen * I82.4Ø2 Acute embolism and thrombosis of unspecified deep veins of left lower extremity * I82.4Ø3 Acute embolism and thrombosis of unspecified deep veins of lower extremity, bilateral * I82.4Ø1 Acute embolism and thrombosis of unspecified deep veins of right lower extremity * I82.4Ø9 Acute embolism and thrombosis of unspecified deep veins of unspecified lower extremity B16.9 Acute hepatitis B without delta-agent and without hepatic coma t t ìv B17.1Ø Acute hepatitis C without hepatic coma N76.Ø Acute vaginitis N76.2 Acute vulvitis M81.Ø Age-related osteoporosis without current pathological fracture N91.2 Amenorrhea, unspecified D64.9 Anemia, unspecified D68.61 Antiphospholipid syndrome Æ Z21 Asymptomatic human immunodeficiency virus [HIV] infection status R87.61Ø Atypical squamous cells of undetermined significance on cytologic smear of cervix [ASC-US] R31.1 Benign essential microscopic hematuria Z22.51 Carrier of viral hepatitis B Z22.52 Carrier of viral hepatitis C R87.81Ø Cervical high-risk human papillomavirus [HPV] DNA test positive Chromosomal abnormality in fetus, affecting management of mother, antepartum C91.1Ø Chronic lymphocytic leukemia of B-cell type not having achieved remission C92.1Ø Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission B18.1 Chronic viral hepatitis B without delta-agent B18.2 Chronic viral hepatitis C D68.9 Coagulation defect, unspecified Z2Ø.6 Contact with and (suspected) exposure to human immunodeficiency virus [HIV] Z2Ø.2 Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission Z2Ø.828 Contact with and (suspected) exposure to other viral communicable diseases Z2Ø.5 Contact with and (suspected) exposure to viral hepatitis (sign or symptom) D72.819 Decreased white blood cell count, unspecified *** E66.1 Drug-induced obesity R97.2 Elevated prostate specific antigen [PSA] D72.829 Elevated white blood cell count, unspecified Z36 Encounter for antenatal screening of mother Ω ZØ9 Encounter for follow-up examination after completed treatment for conditions other than malignant neoplasm p ZØØ.Ø1 Encounter for general adult medical examination with abnormal findings ZØØ.ØØ Encounter for general adult medical examination without abnormal findings p ZØ1.411 Encounter for gynecological examination (general) (routine) with abnormal findings ZØ1.419 Encounter for gynecological examination (general) (routine) without abnormal findings Z13.71 Encounter for nonprocreative screening for genetic disease carrier status Z3Ø.Ø9 Encounter for other general counseling and advice on contraception Z31.438 Encounter for other genetic testing of female for procreative management Z31.49 Encounter for other procreative investigation and testing Z13.79 Encounter for other screening for genetic and chromosomal anomalies Z32.Ø1 Encounter for pregnancy test, result positive Z39.2 Encounter for routine postpartum follow-up Z13.1 Encounter for screening for diabetes mellitus Z11.4 Encounter for screening for human immunodeficiency virus [HIV] Z11.51 Encounter for screening for human papillomavirus (HPV) Z11.3 Encounter for screening for infections with a predominantly sexual mode of transmission Z11.9 Encounter for screening for infectious and parasitic diseases, unspecified ù Z12.4 Encounter for screening for malignant neoplasm of cervix ù Z12.5 Encounter for screening for malignant neoplasm of prostate Z13.89 Encounter for screening for other disorder Z11.8 Encounter for screening for other infectious and parasitic diseases Z13.228 Encounter for screening for other metabolic disorders Z13.29 Encounter for screening for other suspected endocrine disorder Z11.59 Encounter for screening for other viral diseases Z34.Ø1 Encounter for supervision of normal first pregnancy, first
(sign or symptom) Z34.-2 Encounter for supervision of normal first pregnancy, second Z34.Ø3 Encounter for supervision of normal first pregnancy, third Z34.ØØ Encounter for supervision of normal first pregnancy, unspecified Z31.43Ø Encounter of female for testing for genetic disease carrier status for procreative management I1Ø ø R35.Ø K21.9 Essential (primary) hypertension Frequency of micturition Gastro-esophageal reflux disease without esophagitis R31.9 Hematuria, unspecified t K74.Ø Z72.53 Hepatic fibrosis High-risk bisexual behavior Z72.51 High-risk heterosexual behavior Z72.52 High-risk homosexual behavior ** B2Ø R73.9 Human immunodeficiency virus [HIV] disease Hyperglycemia, unspecified E78.5 Hyperlipidemia, unspecified EØ3.9 Hypothyroidism, unspecified D5Ø.9 Iron deficiency anemia, unspecified N92.6 Irregular menstruation, unspecified qà Z79.3 qà Z79.891 R87.612 Long-term (current) use of hormonal contraceptives Long-term (current) use of opiate analgesic Low-grade squamous intraepithelial lesion on cytologic smear of cervix [LGSIL] D68.62 Lupus anticoagulant syndrome C91.9Ø Lymphoid leukemia, unspecified not having achieved remission F32.9 Major depressive disorder, single episode, unspecified C61 Malignant neoplasm of prostate E78.2 Mixed hyperlipidemia ± R53.Ø R74.Ø Neoplastic (malignant) related fatigue Nonspecific elevation of levels of transaminase and lactic acid dehydrogenase [LDH] D53.9 Nutritional anemia, unspecified *** E66.9 Obesity, unspecified Other abnormal findings of blood chemistry R73.Ø9 Other abnormal glucose t K74.69 Other cirrhosis of liver R53.83 Other fatigue R68.89 Other general symptoms and signs E78.4 Other hyperlipidemia Other known or suspected fetal abnormality, not elsewhere classified, affecting management of mother, antepartum condition or complication qà Z79.899 R53.81 Other long-term (current) drug therapy Other malaise Other malignant lymphomas, unspecified site, extranodal and solid organ sites R31.2 Other microscopic hematuria *** E66.8 *** E66.Ø9 Other obesity Other obesity due to excess calories D68.59 Other primary thrombophilia I26.Ø9 Other pulmonary embolism with acute cor pulmonale I26.99 Other pulmonary embolism without acute cor pulmonale R76.8 Other specified abnormal immunological findings in serum D68.8 Other specified coagulation defects (sign or symptom) + E13.9 Other specified diabetes mellitus without complications D72.89 Other specified disorders of white blood cells N92.5 Other specified irregular menstruation B97.7 Papillomavirus as the cause of diseases classified elsewhere D45 Polycythemia vera G93.3 Postviral fatigue syndrome Z33.1 Pregnant state, incidental N91.Ø Primary amenorrhea D68.52 Prothrombin gene mutation E78.Ø Pure hypercholesterolemia R76.Ø Raised antibody titer N96 Recurrent pregnancy loss N91.1 Secondary amenorrhea t N76.1 Subacute and chronic vaginitis t N76.3 Subacute and chronic vulvitis u OØ9.521 Supervision of elderly multigravida, first u OØ9.522 Supervision of elderly multigravida, second u OØ9.523 Supervision of elderly multigravida, third u OØ9.529 Supervision of elderly multigravida, unspecified u OØ9.91 Supervision of high-risk pregnancy, unspecified, first u OØ9.92 Supervision of high-risk pregnancy, unspecified, second u OØ9.93 u OØ9.9Ø Supervision of high-risk pregnancy, unspecified, third Supervision of high-risk pregnancy, unspecified, unspecified Supervision of other high-risk pregnancy Supervision of other normal pregnancy A53.9 Syphilis, unspecified E29.1 Testicular hypofunction D69.6 Thrombocytopenia, unspecified Tobacco use disorder + E11.65 Type 2 diabetes mellitus with hyperglycemia + E11.9 Type 2 diabetes mellitus without complications R1Ø.9 Unspecified abdominal pain R87.619 Unspecified abnormal cytological findings in specimens from cervix uteri t K74.6Ø Unspecified cirrhosis of liver Unspecified hepatitis B19.1Ø Unspecified viral hepatitis B without hepatic coma B19.2Ø Unspecified viral hepatitis C without hepatic coma t N39.Ø Urinary tract infection, site not specified E55.9 Vitamin D deficiency, unspecified R53.1 Weakness
Legend for Symbols * first venous embolism and thrombosis complicating: abortion, ectopic or molar pregnancy (OØØ-OØ7, OØ8.7) pregnancy, childbirth and the puerperium (O22.-, O87.-) Use additional code to identify resistance to antimicrobial drugs (Z16.-) t Use additional code (B95-B97), to identify infectious agent ì Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition v Use additional code to identify: major osseous defect, if applicable (M89.7-) personal history of (healed) osteoporosis fracture, if applicable (Z87.31Ø) Æ first human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-) *** first obesity complicating pregnancy, childbirth and the puerperium, if applicable (O99.21-) Use additional code to identify body mass index (BMI), if known (Z68.-) Use additional code for advserse effect, if applicable, to identify drug (T36-T5Ø with fifth or sixth character 5) Ω Use additional code to identify any applicable history of disease code (Z86-Z87) p Use additional code to identify abnormal findings Use additional code: for screening for human papillomavirus, if applicable (Z11.51) for screening vaginal pap smear, if applicable (Z12.72) to identify acquired absence of uterus, if applicable (Z9Ø.71-) Use additional code for recurrent pregnancy loss, if applicable (N96, O26.2-) ù Use additional code to identify any family history of malignant neoplasm (Z8Ø.-) Use additional code to identify: exposure to environmental tobacco smoke (Z77.22) history of tobacco use (Z87.891) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.Ø) ø first, if applicable, any causal condition, such as: enlarged prostate (N4Ø.1) t also, if applicable, viral hepatitis (acute) (chronic) (B15-B19) ** first human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-) Use additional code(s) to identify all manifestations of HIV infection q also any follow-up examination (ZØ8-ZØ9) À also any therapeutic drug level monitoring (Z51.81) ± first associated neoplasm + Use additional code to identify any insulin use (Z79.4) u Use additional code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy Use additional code to identify any retained foreign body, if applicable (Z18.-) also any associated maternal condition first poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4 or 6) Use additional code for adverse effect, if applicable, to identify drug (T36-T5Ø with fifth or sixth character 5)
Genetic ICD-10-CM Client Aid - Addendum (sign or symptom) Supervision of other normal pregnancy Z34.91 Encounter for supervision of normal pregnancy, unspecified, first Z34.92 Encounter for supervision of normal pregnancy, unspecified, second Z34.93 Encounter for supervision of normal pregnancy, unspecified, third Z34.9Ø Encounter for supervision of normal pregnancy, unspecified, unspecified Z34.81 Encounter for supervision of other normal pregnancy, first Z34.82 Encounter for supervision of other normal pregnancy, second Z34.83 Encounter for supervision of other normal pregnancy, third Z34.8Ø Encounter for supervision of other normal pregnancy, unspecified u OØ9.7Ø u OØ9.71 u OØ9.72 u OØ9.73 u OØ9.891 u OØ9.892 u OØ9.893 u OØ9.899 (sign or symptom) Supervision of other high-risk pregnancy Supervision of high-risk pregnancy due to social problems, unspecified Supervision of high-risk pregnancy due to social problems, first Supervision of high-risk pregnancy due to social problems, second Supervision of high-risk pregnancy due to social problems, third Supervision of other high-risk pregnancies, first Supervision of other high-risk pregnancies, second Supervision of other high-risk pregnancies, third Supervision of other high-risk pregnancies, unspecified (sign or symptom) Other abnormal findings in blood chemistry R79.9 Abnormal finding of blood chemistry, unspecified R78.71 Abnormal lead level in blood R79.Ø Abnormal level of blood mineral R78.79 Finding of abnormal level of heavy metals in blood R78.89 Finding of other specified substances, not normally found in blood E79.Ø Hyperuricemia without signs of inflammatory arthritis and tophaceous disease R79.89 Other specified abnormal findings of blood chemistry (sign or symptom) Other known or suspected fetal abnormality, not elswhere classified, affecting management of mother, antepartum condition or complication O35.8XXØ Maternal care for other (suspected) fetal abnormality and damage, not applicable or unspecified O35.8XX1 Maternal care for other (suspected) fetal abnormality and damage, fetus 1 O35.8XX2 Maternal care for other (suspected) fetal abnormality and damage, fetus 2 O35.8XX3 Maternal care for other (suspected) fetal abnormality and damage, fetus 3 O35.8XX4 Maternal care for other (suspected) fetal abnormality and damage, fetus 4 O35.8XX5 Maternal care for other (suspected) fetal abnormality and damage, fetus 5 O35.8XX9 Maternal care for other (suspected) fetal abnormality and damage, other fetus (sign or symptom) Unspecified hepatitis K75.3 Granulomatous hepatitis, not elsewhere classified K75.9 Inflammatory liver disease, unspecified K75.81 Nonalcoholic steatohepatitis (NASH) K75.2 Nonspecific reactive hepatitis K75.89 Other specified inflammatory liver diseases K76.4 Peliosis hepatis K71.2 Toxic liver disease with acute hepatitis K71.Ø Toxic liver disease with cholestasis K71.51 Toxic liver disease with chronic active hepatitis with ascites
K71.5Ø Toxic liver disease with chronic active hepatitis without ascites K71.4 Toxic liver disease with chronic lobular hepatitis K71.3 Toxic liver disease with chronic persistent hepatitis K71.7 Toxic liver disease with fibrosis and cirrhosis of liver K71.11 Toxic liver disease with hepatic necrosis, with coma K71.1Ø Toxic liver disease with hepatic necrosis, without coma K71.6 Toxic liver disease with hepatitis, not elsewhere classified K71.8 Toxic liver disease with other disorders of liver K71.9 Toxic liver disease, unspecified (sign or symptom) Tobacco use disorder F17.221 Nicotine dependence, chewing tobacco, in remission F17.22Ø Nicotine dependence, chewing tobacco, uncomplicated F17.211 Nicotine dependence, cigarettes, in remission F17.21Ø Nicotine dependence, cigarettes, uncomplicated F17.291 Nicotine dependence, other tobacco product, in remission F17.29Ø Nicotine dependence, other tobacco product, uncomplicated F17.2Ø1 Nicotine dependence, unspecified, in remission F17.2ØØ Nicotine dependence, unspecified, uncomplicated (sign or symptom) Chromosomal abnormality in fetus, affecting management of mother, antepartum O35.1XXØ Maternal care for (suspected) chromosomal abnormality in fetus, not applicable or unspecified O35.1XX1 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 1 O35.1XX2 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 2 O35.1XX3 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 3 O35.1XX4 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 4 O35.1XX5 Maternal care for (suspected) chromosomal abnormality in fetus, fetus 5 O35.1XX9 Maternal care for (suspected) chromosomal abnormality in fetus, other fetus (sign or symptom) Other malignant lymphomas, unspecified site, extranodal and solid organ sites C82.5Ø Diffuse follicle center lymphoma, unspecified site C82.59 Diffuse follicle center lymphoma, extranodal and solid organ sites C84.9Ø Mature T/NK-cell lymphomas, unspecified, unspecified site C84.99 Mature T/NK-cell lymphomas, unspecified, extranodal and solid organ sites C84.AØ Cutaneous T-cell lymphoma, unspecified, unspecified site C84.A9 Cutaneous T-cell lymphoma, unspecified, extranodal and solid organ sites C84.ZØ Other mature T/NK-cell lymphomas, unspecified site C84.Z9 Other mature T/NK-cell lymphomas, extranodal and solid organ sites C85.1Ø Unspecified B-cell lymphoma, unspecified site C85.19 Unspecified B-cell lymphoma, extranodal and solid organ sites C85.2Ø Mediastinal (thymic) large B-cell lymphoma, unspecified site C85.29 Mediastinal (thymic) large B-cell lymphoma, extranodal and solid organ sites C85.8Ø Other specified types of non-hodgkin lymphoma, unspecified site C85.89 Other specified types of non-hodgkin lymphoma, extranodal and solid organ sites C85.9Ø Non-Hodgkin lymphoma, unspecified, unspecified site C85.99 Non-Hodgkin lymphoma, unspecified, extranodal and solid organ sites C86.4 Blastic NK-cell lymphoma 2015 Laboratory Corporation of America Holdings All rights reserved. L13346-0415-1