Midwinter Conference 2015 January 17-22 Seefeld, Tyrol CONFERENCE PROGRAM. midwinter2015.org. Sponsored by

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Midwinter Conference 2015 January 17-22 Seefeld, Tyrol CONFERENCE PROGRAM Sponsored by

SATURDAY, 17 January 18.00-19.00 Keynote lecture Richard Flavell Sponsored by 19.00 Welcome Reception Hosted by SUNDAY, 18 January METABOLISM 09.00-9.30 Manipulation of microbiota and inflammatory Dan Littmann lymphocytes in autoimmune disease New York University 09.30-10.00 Diet and immunity Hermann Wagner Technische Universität München 10.00-10.30 Regulatory T cells and cancer Alexander Rudensky Memorial Sloan-Kettering Cancer Center 11.00-11.30 Novel therapies for diabetes and obesity Mathias Tschoep Helmholtz Center, Technische Universität München 11.30-12.00 TBD Marc Veldhoen University of Cambridge CANCER 14.00-14.30 TYK2-STAT1-BCL2 pathway dependence in Thomas Look T-cell acute lymphoblastic leukemia 14.30-15.00 Cytokine signaling blockade with Jak inhibitors José-Carlos Gutierrez-Ramos in patients Pfizer 15.00-15.30 Molecular mechanism of tolerance to dead cells Peter Krammer German Cancer Research Center (DKFZ)

15.30-16.00 The activities of E- and Id-proteins in immune Cornelis Murre homeostasis University of California, San Diego 16.30-17.00 Cell cycle machinery in development and in Peter Sicinski cancer 17.00-17.30 How to model human lymphomas in mice? Klaus Rajewsky Max Delbrück Center, Berlin 17.30-18.00 Antibodies, Genome Stability, and Cancer Frederik Alt 18.30-20.00 Poster Session / Discussion Rounds Fingerfood will be served MONDAY, 19 January 09.00-9.30 The role of Pax5 in B cell leukemia Meinrad Busslinger Research Institute of Molecular Pathology, Vienna 09.30-10.00 Cell competition and T cell leukemia Hans-Raimer Rodewald German Cancer Research Center (DKFZ) 10.00-10.30 Viral mimics of epigenetic regulators Alexander Tarakhovsky Rockefeller University 11.00-11.30 Immune checkpoint blockade in cancer Jim Allison therapy: New insights and opportunities MD Anderson 11.30-12.00 Arms race in cancer treatment; giving T cells a Stefan Endres help Ludwig-Maximilians University, Munich

17.00-17.30 Cancer therapy by T-cell engaging antibodies Patrick Bäuerle Amgen / Ludwig-Maximilians University, Munich 17.30-18.00 Genome-wide analysis of Notch function in Taras Kreslavsky T cell development Research Institute of Molecular Pathology, Vienna 18.00-18.30 Dissecting immune responses to tumors Philippe Bousso using in vivo imaging Institut Pasteur, Paris 18.30-20.00 Poster Session / Discussion Rounds Fingerfood will be served TUESDAY, 20 January AUTOIMMUNITY 09.00-9.30 TBD Stefan Meuer University of Heidelberg 09.30-10.00 The Helios transcription factor as guardian Harvey Cantor of self-tolerance 10.00-10.30 Enhancing the effectiveness of vaccines by Ken Shortman targeting vaccine antigens to dendritic cells Walter & Eliza Hall Institute, Melbourne 11.00-11.30 Immune tolerance in human autoimmune Carolin Daniel Type 1 Diabetes Helmholtz Center, Munich 11.30-12.00 Central tolerance to autoantigens of the CNS Ludger Klein Ludwig-Maximilians University, Munich 17.00-17.30 T cell subsets in immunity, autoimmunity Federica Sallusto and allergy Institute for Research in Biomedicine, Bellinzona

17.30-18.00 Autoimmune bowel disease Fiona Powrie University of Oxford 18.00-18.30 Immunological phenomena in vascularized Stefan Schneeberger / tissue transplantation Raimund Margreiter University of Innsbruck 18.30-20.00 Poster Session / Discussion Rounds Fingerfood will be served WEDNESDAY, 21 January 09.00-09.30 RORgt+ lymphoid cells in intestinal immunity Gerard Eberl Institut Pasteur, Paris 09.30-10.00 TBD Thomas Brocker Ludwig-Maximilians University, Munich DRUG DISCOVERY 10.00-10.30 TBD Lukas Huber Oncotyrol, Innsbruck 11.00-11.30 Developmental pathways of broadly Antonio Lanzavecchia neutralizing antibodies and autoantibodies Institute for Research in Biomedicine, Bellinzona 11.30-12.00 Human antibodies for HIV prevention and Michel Nussenzweig therapy Rockefeller University, New York 12.00-12.30 Camelid anibodies as novel tool Hidde Ploegh Whitehead Institute, Boston

SHORT TALKS 13.30-15.00 Short Talks 6 x 15 minutes 15.30-17.00 Short Talks 6 x 15 minutes 18.30-20.00 Farewell Reception

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