Katrin Eichelberg, PhD Office of Research Training and Special Programs Division of Extramural Activities, NIAID, NIH keichelberg@niaid.nih.gov June 7 th, 2013
Welcome to Bethesda!
NIH 27 Institutes and Centers Office of the Director on Aging on Alcohol Abuse and Alcoholism of Allergy and Infectious Diseases of Arthritis and Musculoskeletal and Skin Diseases National Cancer Institute of Child Health and Human Development on Deafness and Other Communication Disorders of Dental and Craniofacial Research of Diabetes and Digestive and Kidney Diseases on Drug Abuse of Environmental Health Sciences National Eye Institute of General Medical Sciences National Heart, Lung, and Blood Institute National Human Genome Research Institute of Mental Health of Neurological Disorders and Stroke of Nursing Research National Center for Complementary and Alternative Medicine Fogarty International Center National Center for Advancing Translational Sciences National Library of Medicine of Biomedical Imaging and Bioengineering National Center on on Minority Health Minority Health and and Health Health Disparities Disparities Clinical Center Center for Information Technology Center for Scientific Review no funding authority Different Missions, Responsibilities and Constituencies
Where do I find NIH funding opportunities?
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Information about NIH grants http://grants.nih.gov/grants/guide/index.html
Information about NIH Research Training http://grants.nih.gov/training/index.htm
Information about NIAID Funding Opportunities http://www.niaid.nih.gov/researchfunding/ann/pages/default.aspx
Career Tracks and NIAID/NIH Funding
PhD Career - NIAID T32- Institutional training grant (NRSA)-has pre- & postdoc slots F31- Individual diversity predoc fellowship (NRSA) F32 - Individual postdoc fellowship (NRSA) K01- Mentored Research Scientist Award (epidemiology only) K22- Career Transition Award K25 -Mentored Qualitative Research Development Award K99/R00- Pathway to Independence Award K99/R00 Award Types T32 F31 T32 F32 K01 K25 K22 or K99 R00 RPG High School Student Career Stage Graduate Student Ph.D. Postdoc Phase Faculty Position Independent Investigator Diversity Supplements http://www.niaid.nih.gov/researchfunding/traincareer/pages/careerphd.aspx
MD Career - NIAID T35 - NRSA Short Term Institutional Research Training Grant F30 - Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (NRSA) T32 - Institutional training grant (NRSA)-has pre-& postdoc slots F32 - Individual postdoc fellowship (NRSA) K01 - Mentored Research Scientist Award K08 - Mentored Clinical Scientist Research Career Development Award K23 - Mentored Patient-Oriented Research Career Development Award K24 - Mid-Career Investigator Award in Patient-Oriented Research Award Types T35 F30 T32 F32 K01 K08 K23 K24 RPG Career Stage Medical Student M.D. Clinical Training Phase Fellowship/ Research Training Phase Faculty Position Independent Investigator Diversity Supplements http://www.niaid.nih.gov/researchfunding/traincareer/pages/careermd.aspx
NIAID Newsletter Subscription http://www.niaid.nih.gov/researchfunding/newsletter/pages/subscribe.aspx
Example: Mentored Clinical Scientist Research Career Development Award (Parent K08) FOA
Example: Mentored Clinical Scientist Research Career Development Award (Parent K08) http://grants.nih.gov/grants/guide/pa-files/pa-11-193.html
Example: Mentored Clinical Scientist Research CDA cont. Who should I contact?
NIH 27 Institutes and Centers Office of the Director on Aging on Alcohol Abuse and Alcoholism of Allergy and Infectious Diseases of Arthritis and Musculoskeletal and Skin Diseases National Cancer Institute of Child Health and Human Development on Deafness and Other Communication Disorders of Dental and Craniofacial Research of Diabetes and Digestive and Kidney Diseases on Drug Abuse of Environmental Health Sciences National Eye Institute of General Medical Sciences National Heart, Lung, and Blood Institute National Human Genome Research Institute of Mental Health of Neurological Disorders and Stroke of Nursing Research National Center for Complementary and Alternative Medicine Fogarty International Center National Center for Advancing Translational Sciences National Library of Medicine of Biomedical Imaging and Bioengineering National Center on on Minority Health Minority Health and and Health Health Disparities Disparities Clinical Center Center for Information Technology Center for Scientific Review no funding authority Different Missions, Responsibilities and Constituencies
NIH The People
Please ask for directions!
The NIH Extramural Team Grants Mgmt Program Staff Review Staff Grants Management Staff Monitor grant award, renewals, and closing Negotiate and coordinate with university business officials Ensure compliance with NIH policy Ensure financial accountability Program Staff Advise you before you submit your appl. Monitor the review process Discuss options with you after review Make funding recommendations Manage research grants after they are awarded Review Staff Assign your application to a review group Recruit scientists to serve on study sections Organize and run peer review meetings Provide feedback via the summary statement
What should I asked a Program Officer? Dear Dr. Eichelberg, I was hoping to inquire about potentially applying for a K award under the NIAID. (actual email - May 2013) Send a draft of your biosketch and specific aims (1 page). Is the proposed research area a good fit for your IC? Would the K08 be the most suitable grant mechanism for me? Specific questions that may be unique to your situation. Any other advice?
General Principles of Career Development and LRP Awards
Career Development Awards (Ks) Individual awards Several for MDs (K01, K08, K23, K24) to support development to become an independent investigators More senior award than a clinical fellowship Some mentored, others are not PhDs (MDs): Mostly K22 and K99/R00: transition awards; also K01 and K25 Salary for mentored awards: $75-90K + $25-50K research support; F&A 8% NIAID POC: Katrin Eichelberg (keichelberg@niaid.nih.gov)
Review Criteria for NIH Career Development Awards Overall Impact. Reviewers should provide their assessment of the likelihood for the candidate to maintain a strong research program, taking into consideration the criteria below in determining the overall impact/priority score. NEW: revised scoring guidance for Ks Candidate Career Development Plan/Career Goals & Objectives Research Plan Mentor(s), Co-mentor(s), Consultant(s), Collaborator(s) Environment and Institutional Commitment to the Candidate http://grants.nih.gov/grants/peer/critiques/k.htm NIAID CDA applications are reviewed at the NIAID Scientific Review Program by 4 chartered committees (AIDS, AITC, MID and MID-B)
Physician Scientist: Should I apply for a K08 or K23? Mentored Clinical Scientist Research Career Development Award (K08) Candidate may propose basic research project Mentored Patient-Oriented Research Career Development Award (K23) Candidate may only propose Patient-Oriented Research (POR). POR is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects. K08/23: 3 to 5 yr award Salary: $90,000/yr Research Support: $50,000/yr Review of applications is essentially the same.
K08/K23s: Important NIAID Policies NIAID Eligibility Requirements for (K08/K23) Grant Applications http://grants.nih.gov/grants/guide/notice-files/not-ai-06-002.html Candidates must have a health professional doctoral degree, such as the M.D., D.O., D.V.M., or equivalent degree, and a professional license to practice in the United States. Career development award applications and NIAID Policy on Support of Clinical Trials http://grants.nih.gov/grants/guide/notice-files/not-ai-08-041.html NIAID will not accept K-series applications proposing to conduct new, free-standing clinical trials or studies. Any proposed clinical trial or study in a K application must be part of an ongoing clinical trial or program, generally the mentor s. Career development applicants are encouraged to participate in the planning, design, and implementation of these ongoing clinical trials and studies in order to gain the training and experience necessary to become independent clinical investigators.
Buried in student loans? LRP to the rescue!
Loan Repayment programs (LRP) NIH wants to encourage outstanding health professionals to pursue careers in biomedical, behavioral, social, and clinical research. If you commit at least two years to conducting qualified research funded by a domestic nonprofit organization or U.S. federal, state, or local government entity, NIH may repay up to $35,000 of your qualified student loan debt per year. Loan repayment benefits are in addition to the institutional salary you receive for your research. Clinical Research Pediatric Research Health Disparities Research Contraception and Infertility Research Clinical Research LRP for Individuals from Disadvantaged Backgrounds General LRP site: http://www.lrp.nih.gov/index.aspx A recorded overview webinar from the LRP Office: http://go.usa.gov/ahx
LRP Clinical and Pediatric Program Goal: The NIH Loan Repayment Programs supports M.D.s and other doctoral-level professionals pursue research careers by repaying qualifying educational debt. Clinical Research Patient-oriented research conducted with human subjects, or research on the causes and consequences of disease in human populations involving material of human origin (such as tissue specimens and cognitive phenomena) for which an investigator or colleague directly interacts with human subjects in an outpatient or inpatient setting to clarify a problem in human physiology, pathophysiology or disease, epidemiologic or behavioral studies, outcomes or health services research, or developing new technologies, therapeutic interventions, or clinical trials. Pediatric Research Research that is directly related to diseases, disorders, and other conditions in children, including pediatric pharmacology.
Life Cycle of a NIH grant application University Submits Application Electronic Submission s of Health Assign to Institute and Study Section Funding cycle Peer Review Take Action Recommend Action Leaders in the biological and medical sciences, education, health care, and public affairs. Evaluate Relevance Institute (24 with funding authority) Review of Scientific Merit 1946
Tools and Resources
NIH Funded Research - RePORT Search Many New Categories Over 200 disease categories Keywords RFA/PA Investigator Organization Funding mechanism Recovery Act Location Study Section http://report.nih.gov/ http://projectreporter.nih.gov/reporter.cfm