- Introduction to Bionanotechnology -



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Oxford Nanotechnology Summer School, 2-6 July 2012 - Introduction to Bionanotechnology - University of Oxford, Ewert House, Summertown OX2 7DD Introduction to Cell Biology and Bionanotechnology Monday 2 July 2012 9.30 10.30 What is bionanotechnology? Challenges and opportunities. Page 1 of 5 Prof. Peter Dobson 10.30 11.00 Introduction to nucleic acids Dr Helen Townley 11.00 11.30 COFFEE 11.30 12.00 Introduction to proteins Dr Helen Townley 12.00 12.45 Proteins, lipids and sugars Dr Mark Wormald 12.45 14.00 LUNCH 14.00 14.45 Cells and their components Miss Cordelia Rampley 14.45 15.15 Mammalian cell culture Mrs Celine Jones 15.15 15.45 Bacterial cell culture Dr Duane Ager 15.45 16.15 TEA 16.15 17.00 Tissue engineering and applications Prof. Zhangfeng Cui 17.30 19.30 Drinks reception at Kellogg College Dr Helen Townley (Oxford Centre for Imaging in Cancer, Department of Engineering Dr Mark Wormald (Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford) Miss Cordelia Rampley (D.Phil. student in Chemical Environmental Engineering, University of Oxford) Mrs Celine Jones (Nuffield Department of Obstetrics and Gynaecology, University of Oxford) Dr Duane Ager (Department of Engineering Prof. Zhangfeng Cui (Institute of Biomedical Engineering, Department of Engineering

Introduction to Bioanalytical Techniques Tuesday 3 July 2012 9.30 10.30 Techniques for protein analysis Dr Helen Townley 11.00 11.30 Introduction to techniques for DNA analysis Prof. Sir Ed Southern 11.30 12.15 Fluorescence-based single-molecule DNA sequencing Dr Achillefs Kapanidis 12.15 13.00 DNA Microarrays Dr Douglas Hurd - OGT 14.00 14.45 Imaging the science of life optical microscopy in biology 14.45 15.30 Biological Transmission Electron Microscopy (TEM) 15.30 16.15 Atomic Force Microscopy (AFM) of biological systems 16.15 17.00 TEA (equipment demonstrations) 17.30 19.00 Lab tours in Departments of Physics and Chemistry Dr Susan Brooks Dr Louise Hughes Dr Chandra Ramanujan tbc. Dr Helen Townley (Oxford Centre for Imaging in Cancer, Department of Engineering Prof. Sir Edwin Southern (Emeritus Professor of Biochemistry, University of Oxford; Chairman, Chief Scientific Officer of Oxford Gene Technology Limited) Dr Achillefs Kapanidis (Biological Physics, Department of Physics, University of Oxford) Dr Douglas Hurd (Oxford Gene Technology, Begbroke Science Park, Oxfordshire) Dr Susan Brooks (Faculty of Health & Life Sciences, Oxford Brookes University) Dr Louise Hughes (Faculty of Health & Life Sciences, Oxford Brookes University) Dr Chandra Ramanujan (Department of Physics, University of Oxford) Page 2 of 5

Applied Genomics and Proteomics Wednesday 4 July 2012 9.30 10.30 Introduction to Proteomics Dr Benjamin Thomas 11.00 12.00 Clinical proteomics: How protein techniques help in evidence based medicine Dr Ross Sadler 12.00 13.00 Protein expression systems Dr Nicola Burgess- Brown 14.00 14.45 Genetic technologies for Sterile Insect Technique 14.45 15.30 DNA sequencing using engineered protein nanopores 15.30 16.00 TEA Dr Luke Alphey OXITEC Prof. Hagan Bayley 16.00 17.00 Forensic DNA analysis Matthew Greenhalgh Cellmark Forensics 17.00 17.15 Discussion and summary 18.00 20.00 Oxford Walking Tour Dr Benjamin Thomas (Central Proteomics Facility, Sir William Dunn School of Pathology, University of Oxford) Dr Ross Sadler (Oxford Radcliffe NHS Trust) Dr Nicola Burgess-Brown (Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford) Dr Luke Alphey (Oxitec Ltd, Abingdon, Oxfordshire) Prof. Hagan Bayley FRS (Department of Chemistry, University of Oxford) Mr Matthew Greenhalgh (Cellmark Forensic Services, Abingdon, Oxfordshire) Page 3 of 5

Nanoparticles, Nanostructures and Biomimetics Thursday 5 July 2012 9.30 10.30 Natural and incidental nanoparticles Prof. Peter Dobson 11.00 12.00 Applications of nanoparticles Dr Barry Park 12.00 13.00 Engineered nanoparticles and their syntheses Dr Josie Goodall 14.00 14.30 Biologically inspired nanostructures introduction to biomimetics Prof. Peter Dobson 14.30 15.15 Biomimetics of photonic nanostructures Prof. Andrew Parker 15.15 15.45 TEA 15.45 16.15 Hydrophobic coatings and their applications Dr Delwyn Evans P2i 16.15 17.00 Spider silk and novel bio-inspired synthetic polymers Dr Chris Holland 17.00 17.15 Discussion and summary Dr Barry Park (Director, GBP Consulting Ltd, and Theme Manager, Chemical and Consumer Products, Nanotechnology Knowledge Transfer Network) Dr Josie Goodall (Department of Chemistry, University College London) Prof. Andrew Parker (Department of Zoology, The Natural History Museum, London, and Green Templeton College, University of Oxford) Dr Delwyn Evans (P2i, Abingdon, Oxfordshire) Dr Chris Holland (Oxford Silk Group, Department of Zoology, University of Oxford) Page 4 of 5

Interaction of Nanomaterials with Biological Systems Friday 6 July 2012 9.30 10.30 Nanoparticle interactions at the cellular level Dr Joshua Rappoport 11.00 12.00 Nanomaterial interactions at a whole organism level Prof. Teresa Fernandes 12.00 13.00 Nanoparticles in medicine Prof. Peter Dobson 14.00 14.45 Nanoparticles and their fate in the environment 14.45 15.30 Environmental risk assessment of nanoparticles 15.30 15.45 Ecotoxicology of silver and zinc nanoparticles to freshwater microbial communities 15.45 16.00 Silver nanoparticles - an example of potential hormesis in C. elegans 16.00 16.30 TEA 16.30 17.00 Nanotechnology and environmental remediation 17.00 17.30 Discussion and summary Prof. Jamie Lead Dr Claus Svendsen Dr Marianne Matzke Dr Bill Tyne Prof. Ian Thompson Dr Joshua Rappoport (Birmingham Advanced Light Microscopy (BALM) Facility, School of Biosciences, University of Birmingham) Prof. Teresa Fernandes (School of Life Sciences, Heriot-Watt University, Edinburgh) Prof. Jamie Lead (Director of the Facility for Environmental Nanoscience Analysis and Characterisation (FENAC), School of Geography, Earth and Environmental Sciences, University of Birmingham) Dr Claus Svendsen (Centre for Ecology and Hydrology, Wallingford, Oxfordshire) Dr Marianne Matzke (Centre for Ecology and Hydrology, Wallingford, Oxfordshire) Dr Bill Tyne (Centre for Ecology and Hydrology, Wallingford, Oxfordshire) Prof. Ian Thompson (Department of Engineering Page 5 of 5