510(K) SUMMARY. 510(k) Number KOS'00-r



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" iirtual Ports Virtsua Ports Virtual Ports Ltd. 510(K) SUMMARY 510(k) Number KOS'00-r MAR 2 12008 Applicant's Name: Contact Person: Trade Name: Common name: Classification: Predicate Devices: Device Description: Virtual Ports Teradion Industrial Park 6 Kahol Street D.N Misgav 20179 ISRAEL Tel: (972)4-999-0189 Fax: (972)4-999-1901 Yoram Levy, Qsite 31 Haavoda Street Binyamina, Israel 30500 Tel (972)4-638-8837; Fax (972)4-638-0510 Yoram~qsitemed.com EndoClearTM system Accessory to a Laparoscope Name: Endoscope and accessories Product Code: GCJ Regulation No: 876.1500 Class: II Classification Panel: General and Plastic Surgery Substantial equivalence to the following predicate device is claimed: 1. Laparoscope and Monopolar laparoscopic instruments; Instrmmed International, Inc. K040855. 2. g-lixtm Tissue Grasper; USGI Medical K061268 The Virtual Ports EndoClearTM system is a sterile, single patient use system consisting of: EndoClearTM Lens Cleaner and the EndoClearTM Introducer. The EndoClear T M Lens Cleaner is an internally anchored, hands-free, laparoscope lens cleaning device which is attached to the internal abdominal cavity wall and remains in position until 2-2 Virtual Ports Ltd. I EndoClearTM 510k Notification

/Virtual Ports irtal rsystems Virtual Ports Ltd. completion,of the surgery, enabling the surgeon to effectively clean the lens of blood, fat, fog, and secretions without removing it from the cavity. The Virtual Ports EndoClearTM Lens Cleaner is introduced via a cannula using the EndoClearTM Introducer, which also removes the EndoClearT M Lens Cleaner at the end of the surgical procedure. Intended Use Statement: EndoClearTM Laparoscopes Accessory is intended to be used by qualified physicians to provide endoscope lens cleaning for uninterrupted visualization of internal structures in a wide variety of diagnostic and therapeutic laparoscopic procedures. Performance Validation: Performance Testing - bench tests Series of bench tests were performed to ensure that the device performs as intended. All testing results demonstrated satisfactory performance. Performance Testing - animal An animal study was performed in order to evaluate the safety and Tests conclusion: Materials: effectiveness of using the Virtual Ports EndoCleafr M System as an internal endoscope lens cleaner, This study demonstrated that the EndoClearT M I system performs as intended and that no safety and effectiveness questions were raised. Both bench tests and the animal study were shown that the device performs safely and efficiently in accordance with its intended use. 2-3 Virtual Ports Ltd. I EndoClearTM 510k Notification

!.~ ~?:'f_?- ~ ~-. '<'~.1;Virtual Ports Ltpaoscopy sto,,s Virtual Ports Ltd. Materials of the EndoClear TM device that are in contact with the human body are biocompatible in accordance with ISO 10993-1. Substantial Equivalence: Preclinical and bench performance data was supplied to demonstrate that the EndoClear TM meets its labeled performance claims, and to demonstrate! substantial equivalence to the predicate devices. 2-4 Virtual Ports Ltd. I EndoClearTM 510k Notification

DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service %¾ Food and Drug Administration 9200 Corporate Boulevard Rockville MD 20850 Virtual Ports % Qsite Yoram Levy General Manager 31 Haavoda Street Binyamina, Israel MAR 2 1 2008 Re: K080051 Trade/Device Name: EndoClear TM Regulation Number: 21 CFR 876.1500 Regulation Name: Endoscope and accessories Regulatory Class: II Product Code: GCJ Dated: March 5, 2008 Received: March 10, 2008 Dear Yoram Levy: We have reviewed your Section 510(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce: prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. If your device is classified (see above) into either class II (Special Controls) or class III (PMA), it may be subject to such additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register. Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CFR Part 807); labeling (21 CFR Part 801); good manufacturing practice requirements as set

Page 2 - Yoram Levy forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. This letter will allow you to begin marketing your device as described in your Section 510(k) premarket notification. The FDA finding of substantial equivalence of your device to a legally marketed predicate device results in a classification for your device and thus, permits your device to proceed to the market. If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Center for Devices and Radiological Health's (CDRH's) Office of Compliance at (240) 276-0115. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (21CFR Part 807.97). For questions regarding postmarket surveillance, please contact CDRH's Office of Surveillance and Biometric's (OSB's) Division of Postmarket Surveillance at (240) 276-3474. For questions regarding the reporting of device adverse events (Medical Device Reporting (MDR)), please contact the Division of Surveillance Systems at (240) 276-3464. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (240) 276-3150 or at its Internet address http:/iwww.fda.gov/cdrh/industry/support/index.htrnl. Enclosure Sincerely yours, c4:3vr&4l Mark N. Melkerson Director Division of General, Restorative and Neurological Devices Office of Device Evaluation Center for Devices and Radiological Health

Lo ot Virtual Ports Laparscopy ste,, Virtual Ports Ltd. INDICATIONS FOR USE STATEMENT 510(k) Number (if known): Device Name: EndoClearTM System Indications for Use: EndoClearTM Laparoscopes Accessory is intended to be used by qualified physicians to provide endoscope lens cleaning for uninterrupted visualization of internal structures in a wide variety of diagnostic and therapeutic laparoscopic procedures. Prescription Use x AND/OR Over-The-Counter Use (Part 21 CFR 801 Subpart D) (21 CFR 801 Subpart C) (PLEASE DO NOT WRITE BELOW THIS LINE -CONTINUE ON ANOTHER PAGE IF NEEDED) Concurrence of CDRH, Office of Device Evaluation (ODE) (Division Sign-off) Division of Division of General, Restorative and Neurological Devices 510(k) Number 4 (Division SigW ~Off) Division of Gep*'nvi-, Restorative, and Neurologital Devices 510(k) Number_.J goo 0 1 1-2 Virtual Ports Ltd. I EndoClearTm 510k Notification