MAY 2 1 2913. Attachment4. 5 10(k) Summary 21 CER 872.3640



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MAY 2 1 2913 Traditional 510(k) Submission DIO tjf HSA Internal Sub-Merged Implant System Attachment4 5 10(k) Summary This summary of 5 10(K) safety and effectiveness information is being submitted in accordance with the requirements of 21 CFR Pant 807.92. Preparation date :Feb 15, 2013 1. Submitter 010 Corporation 66. Centumnseo-ro, H-aeundae-gu, B usan, Korea Tel. :82-51-745-7777 Fax. :82-51-745-7778 2. US Agent / 01, USA Tim C.J. Lee Contact Person 3540 Wilshire Blvd. #1104 Los Angeles, CA 90010, USA Tel. :213-365-2875 Fax. :213-365-1595 3. Trade Name DIO UP HSA Internal Sub-Merged Implant System 4. Common Name Dental Implant 5. Classifi cation Name Endosseous Dental Implant 21 CFR 872.3640 Classli DZE, NI-IA Endosseous Dental implant abutment 21 CER 872.3640 Classll DZE. NHA 6. Predicate Devices Implantium 11 (510(k) No: K060501) 7. Device Description The 010 UP HSA Internal Sub-Merged Implant System is comprised of dental implants, superstructures, instruments for prosthetics and surgical instruments. The 010 UP HSA Internal Sub-Merged Implant System is specially designed for use in dental implant surgery. A successfully osseointegrated implant will achieve a -60-

Traditional 5 10(k) Submission DiO UF HSA Internal Sub-Merged Implant System firm implant when surgically implanted under controlled conditions, per well known clinical studies. There are intended for use in partially or fully edentulous mandibles and maxillae, in support of single or multiple-unit restorations. The DIO UP HSA Internal Sub-Merged Implant System, fixtures are made of commercial pure titanium, grade 4(ASTM F67) which have a S.L.A (Sand-blasted Large grit Acid-etched) treated surface. These fixtures can be used one-stage surgery method or two-stage surgery method. And that are surgically inserted into the upper and/or lower jaw bone. The fixtures replace tooth root as providing a stable foundation for restorations. The fixtures have the diameter(3.8-7.omm)and length.(7 -~ 16mm) Geometrically, the implant is screw-type. An abutment is connected to the implant through a tapered-joint. The device functions by being surgically implanted in the bone of the upper or lower jaw arches in order to provide support for a prosthetic device, such as an artificial tooth, in order to restore a patient's chewing function. With regard to the scientific concepts that form the basis for the device, root-form endosseous dental implant devices are characterized by four geometrically distinct types. The 010 UF HSA Internal Sub-Merged Implant System is a screw endosseous dental -implant. With regard to the physical and performance characteristics of The 010 UF HSA Internal Sub-Merged Implant System, the design shape, engaging method, implant surface treatment and dimensions (lengths and diameters) are the same as the lawfully marketed predicate device. Test performned in air at 24'C. at 14Hz frequency for at least 5x 106 cycles. TilIti ng angles of' specimen is 35'. The Fatigue limit is over 250N (Fracture or cracks or severe distortion of' any parts were not detected.). It is the same fatigue limit of predicate device. -61-

Traditional 510(k) Submiission DIO UF HSA Internal Sub-Merged Implant System Substantial Equivalence Comparison There are no known technological differences between the DIG UF HSA Internal Sub-Merged Implant System and Implantium II. Subject Device Predicate Device MauatrrDIG Corporation Dentiumn Co., Ltd. Name The DIG UF HSA Internal Sub-Merged Implant System is indicated for surgical placement in the upper and lower jaw Implantium II is intended to be arches, to provide *a root form means for surgically placed in the bone of the single or multiple units' prosthetic upper or lower jaw arches to Intended Use attachment to restore a patient's chewing provide support for prosthetics function. Implants can be placed with a devices, such as artificial teeth, and conventional two stage surgical process to restore the patient's chewing with an option for transmucosal healing function. or they can be placed in a single stage surgical process for immediate loading. Fixture Material CP Ti Gr4 (ASTM F67) CP Ti 0r4 (ASTM F67) Design Internal Type and Morse Tapered Internal Type and Morse Tapered Screw Threads YES YES -62-

Ic 9415i Traditional 510(k) Submission 010 UP HSA Internal Sub-Merged Implant System Implant 3.8 7.0.3.6 5.0 Diameters(mm) Implant 7-16 8-14 Lengths(mm) Surface S.L.A (Sand-blasted Large grit S.L.A (Sand-blasted Large grit Treatment Acid-etched) Acid-etched) Sterilization Method Gamma Gamma Abutment 4.0-7.5 4.5-7.5 Diameters(mm) AumnCuf1.5-5.5 1.0-5.5 Lengths(mm) Abutment Max. 25* Max. 25' Angulation(o) Abutment Surface Treatment Abutment Machined type TiN Coating Sterilization Non Sterilization Non Sterilization CP T G4 Gr, (ATM 67) CP Ti Gr2, Gr3, Gr4 (ASTM F67) Material Ti Alloy(ASTM F136:Ti-6A1-4V ELI) Attchmnts Various abutments and components Various abutments and components 8. Indication for use The DIO UF I-ISA Internal Sub-Merged Implant Systemn is indicated for surgical placement in the upper and lower Jaw arches, to provide a root fonni means for single or multiple units' prosthetic attachment to restore a patient's chewing Function. The smaller (03.8 -- 05.5) implants can be placed with a conventional two stage surgical process with an option for transmucosal healing or- they can be placed in a single stage sugclprocess for imnmediate loading when good primary stability is achieved with appropriate occlusal loading. TIhe larger (06.0 -- 67.0) implants can he placed with a conventional two stage surgical process with an option for transrnucosal healing and are indicated for the molar region with delayed loading. -63-

Traditional 510(k) Submission DIO UF HSA Internal Sub-Merged Implant System 9. Review The DIO UF HSA Internal Sub-Merged Implant System has same material and similar indication for used, design and technological characteristics as the predicate device. The DIO UF HSA Internal Sub-Merged Implant System has been subjected to safety, performance and product validation prior to release. Safety tests including biocompatibility has been performed to ensure the devices comply with the applicable International and US regulations. 10. Summary of nonclinical testing Fatigue testing was conducted according to the "Guidance for industry and FDA staff Class 11 Special Controls Guidance Document Root-form Endlosseous Dental Implants and Endlosseous Dental Abutment" with the worst case scenario of the DIO I-SA STEADY Internal Sub-Merged Fixture and an angled abutment. Therefore, the fatigue test result of DIO UF HSA Internal Sub-Merged Implant System performs as intended. 11. Conclusion The evaluation of the DIO UF I-SA Internal Sub-Merged Implant System does not raise any additional concerns regarding safety and effectiveness and may therefore be considered substantially equivalent to its predicate device. Date Feb/ 151 2013 Gab-moon,Jeong/ DIO Corporation RA Staff Date Feb/ 15/ 2013 Tim C.J. Lee/ DIO, USA Manager -64 -

DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service 0~ Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - W066-G609 Silver Spring, MD) 20993-0002 May 213,2013 DIO Corporation C/O Mr. Timothy C.J. Lee Manager DIO USA 3540 Wilshire Boulevard, #1104 LOS ANGELES CA 90010 Re: K122519 Trade/Device Name: DIO UF HSA Internal Sub-Merged Implant System Regulation Number: 21 CER 872.3640 Regulation Name: Endosseous Dental Implant Regulatory Class: DZE, NHA Product Code: 11 Dated: May 6, 2013 Received: May 6, 2013 Dear Mr. Lee: We have reviewed your Section 5 10(k) premarket notification of intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use stated in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, market the device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you, however, that device labeling must be truthful and not misleading. If your device is classified (see above) into either class 11 (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 2 1, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Page 2 - Mr. Lee Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CER Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical devicerelated adverse events) (21 CFR 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Pant 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please contact the Division of Small Manufacturers, International and Consumer Assistance at its tollfree number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www.fda.gov/medicaldevices[resourcesforyou/industry/default.htm. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (2ICFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://wwwvra.fda.gov/medical]devices/safetyreportaproblem/default.htm for the CDRH' s Office of Surveillance and Biometrics/Division of Postmarket Surveillance. You may obtain other general information on your responsibilities under the Act from t he Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address littp://www.fda.gov/medicaldevices/resourcesforyou/industr/default.htim. Sincerely yours, K am 7 r1 0qU'/ merv for Anthony D. Watson, B.S., M.S., M.B.A. Director Division of Anesthesiology, General Hospital, Respiratory, Infection Control and Dental Devices Office of Device Evaluation Center for Devices and Radiological Health Enclosure

Traditional 5t0(k) Submission DIO UF H-SA Internal Sub-Meroed Implant System Attachment 2 Indications for Use Statement 510(K) Number (if known): I ~jc Device Name : DIO Up HSA Internal Sub-Merged Implant System Indications For Use: The 010 UT HSA Internal Sub-Merg-ed Implant System is indicated for suru-ical placement in the Upper and lower Jaw arches, to provide a root form means for singlde or multiple units' prosthetic attachment to restore a patient's chcwinq function. The smaller (03.8-05.5) implants can be placed with a conventional two stage, surgical process with atn option for transmucosal healing- or they can be placed-c i a single stage, surgical process for immediate loading when good primary stability is achieved with appropriate occiuisal loading. The larger (06.0 -- 07,)) imiplants can be placed with a conventional two stag~e surgical process with ain option for transmnucosal healing, and are indicated for the miolar reg'ion w ith delay'ed loading. Prescription Use I/ AND/OR Over-The-Counter Use (Part 21 CFR 801 Subpart D) (21 CER 801 Subpart C) (PLEASE DO NOT WRITE BELOW THIS LINE-CONTINTUE. ON ANOTHER PAGE IF NEEDED) ON W cus ous. Goverment ou=hhs, (Division Sign-Off)q Division of Anesthes*1ol0y, General Hospital Infection Control, Dental Devices.,-Ilnk) Number: k0\ 92- _,DPH office of Device Evaluation (ODE).W-F6 'dy 4 yow,cn=ma.5.,-, 1200300.10.1.1=1300879S0 III ~''nln~page I of I '-58 -