GE Healthcare MAR 1 2013



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K130155 Pagel1 of 2 GE Healthcare MAR 1 2013 510(k) Summary In accordance with 21 CFR 807.92 the following summary of information is provided: Submitter: Primary Contact Person: Secondary Contact Person: Date: January 17, 2012 9900 Innovation Drive Wauwatosa, WI 53226 Kristin Pabst Regulatory Affairs Manager Phone: (414) 721-3104 Fax: (414) 721-3863 Doug Kentz Regulatory Affairs Phone (414) 362-2038 FAX: (414) 362-2585 Device: Trade Name: MUSE Cardiology Information System Common/Usual Name: EGG Analysis Computer Classification Names: Programmable Diagnostic Computer (21 CFR 870.1425) Product Code: DQK Predicate Device(s): MUSE Cardiology Information System K#1 10132 Device Description: Intended Use: The MUSE Cardiology Information System is a network PC-based system comprised of a client workstation/server configuration that manages adult and pediatric diagnostic cardiology data by providing centralized storage and ready access to a wide range of data/reports (e.g. Resting EGG, Stress, Holter, HiRes) from GE and non-ge diagnostic and monitoring equipment. The device provides the ability to: *Review and edit stored data consisting of measurements, text, and digitized waveforms on screen, through the use of reviewing, measuring, and editing tools including EGG serial comparison and interpretive 12-lead analysis. *Generate formatted management reports, ad-hoc database search reports and clinical patient reports on selected stored data. The MUSE Cardiology Information System is intended to store, access and manage cardiovascular information on adult and pediatric patients. The information consists of measurements, text, and digitized waveforms. The MUSE Cardiology Information System provides the ability to~ review and edit electrocardiographic procedures on screen, through the use of reviewing, measuring, and editing tools including EGG serial comparison and interpretive 12-lead analysis. The MUSE Cardiology Information System is intended to be used under the direct supervision of a licensed healthcare practitioner, by trained operators in 17

K130155 Page 2 of 2 GE Healthcare Technologyv: Determination of Substantial Equivalence: Conclusion: a hospital or facility providing patient care. The MUSE Cardiology Information System is not intended for real time monitoring. The MUSE Cardiology Information System is not intended for pediatric serial comparison. The proposed MUSE Cardiology Information System employs the same functional scientific technology as the predicate device MUSE Cardiovascular Information System (K1 10132). Summary of Non-Clinical Tests: The MUSE Cardiology Information System complies with voluntary standards: * IEC 60601-1-1:200l Medical Electrical Equipment - Part 1-1: General Requirements for Safety - Collateral Standard: Safety Requirements for Medical Electrical Systems, 2 nd Edition * IEC 60601-1-2:2007 Medical Electrical Equipment - Part 1-2: General Requirements for Safety - Collateral standard: Electromagnetic Compatibility - Requirements and Tests, Edition 3 * 1EC 60601-1-4:2000 Medical Electrical Equipment - Part 1-4: General Requirements for Safety - Collateral Standard: Programmable Electrical Medical Systems, Edition 1.1 * ISO 14971:2009 Medical devices - Application of risk management to medical devices, 2 ndedition The following quality assurance measures are applied to the development of the system: * Risk Analysis ** Requirements Reviews * Design Reviews - * Code Inspection * Testing on unit level (Module verification) * Integration testing (System verification) * Performance testing (Verification) * Safety testing (Verification) * Simulated use testing (Validation) Summary of Clinical Tests: The subject of this premarket Submission, MUSE Cardiology Information System, did not require clinical studies to support substantial equivalence. GE Healthcare considers the MUSE Cardiology Information System to be as safe, as effective, and performance is substantially equivalent to the predicate device. 18

-4. Food DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service and Drug Administration 10903 New Haimpshire Avenue Document Control Center - W066-0609 Silver Spring, MD 20991-0002 March 1, 2013, Inc. d/o Ms. Kristin Pabst 9900 West Innovation Drive Wauwatosa, WI 53226 Re: K 130155 Trade/Device Name: MUSE Cardiology Information System Regulation Number: 21 CFR 870.1425 Regulation Name: Programmable Diagnostic Computer Regulatory Class: Class II (two) Product Code: DQK Dated: January 18, 2013 Received: January 25, 2013 Dear Ms. Kristin Pabst: We have reviewed your Section 5 10(k) premarket notificationof intent to market the device referenced above and have determined the device is substantially equivalent (for the indications for use state d in the enclosure) to legally marketed predicate devices marketed in interstate commerce prior to May 28, 1976, the enactment date of the Medical Device Amendments, or to devices that have been reclassified in accordance with the provisions of the Federal Food, Drug, and Cosmetic Act (Act) that do not require approval of a premarket approval application (PMA). You may, therefore, marketrthe device, subject to the general controls provisions of the Act. The general controls provisions of the Act include requirements for annual registration, listing of devices, good manufacturing practice, labeling, and prohibitions against misbranding and adulteration. Please note: CDRH does not evaluate information related to contract liability warranties. We remind you; however, that device labeling must be truthful and not misleading. If your device is classified (see above) into either class 11 (Special Controls) or class III (PMA), it may be subject to additional controls. Existing major regulations affecting your device can be found in the Code of Federal Regulations, Title 21, Parts 800 to 898. In addition, FDA may publish further announcements concerning your device in the Federal Register.

Page 2 - Ms. Kristin Pabst Please be advised that FDA's issuance of a substantial equivalence determination does not mean that FDA has made a determination that your device complies with other requirements of the Act or any Federal statutes and regulations administered by other Federal agencies. You must comply with all the Act's requirements, including, but not limited to: registration and listing (21 CER Part 807); labeling (21 CFR Part 801); medical device reporting (reporting of medical device-related adverse events) (21 CER 803); good manufacturing practice requirements as set forth in the quality systems (QS) regulation (21 CFR Part 820); and if applicable, the electronic product radiation control provisions (Sections 531-542 of the Act); 21 CFR 1000-1050. If you desire specific advice for your device on our labeling regulation (21 CFR Part 801), please go to http://www.fdajzov/aboutfda/centersoffices/cdrh/cdlrhoffices/ucm II 5809.htm for the Center for Devices and Radiological Health's (CDRI-'s) Office of Compliance. Also, please note the regulation entitled, "Misbranding by reference to premarket notification" (2ICFR Part 807.97). For questions regarding the reporting of adverse events under the MDR regulation (21 CFR Part 803), please go to http://www.fda.gyov/medicaldevices/safetv/[reportaproblem/default.htm for the CDRH's Office of Surveillance and Biometrics/Division of Postmarket Surveillance. You may obtain other general information on your responsibilities under the Act from the Division of Small Manufacturers, International and Consumer Assistance at its toll-free number (800) 638-2041 or (301) 796-7100 or at its Internet address http://www. fda.gov/medical Devices/ResourcesforYou/lndustry/default.htm. Enclosure for Sincerely yours, Oweh_ P-. Fa rls -S Brain D. Zuckerman, M.D. Director Division of Cardiovascular Devices Office of Device Evaluation Center for, Devices and Radiological Health

GE Healthcare 510(k) Number: K130155 Device Name: MUSE Cardiology Information System Indications for Use: The MUSE Cardiology Information System is intended to store, access and manage cardiovascular information on adult and pediatric patients. The information consists of measurements, text, and digitized waveforms. The MUSE Cardiology Information System provides the ability to review and edit electrocardiographic procedures on screen, through the use of reviewing, measuring, and editing tools including ECG serial comparison and interpretive 12-lead analysis. The MUSE Cardiology Information System is intended to be used under the direct supervision of a licensed healthcare practitioner, by trained operators in a hospital or facility providing patient care. The MUSE Cardiology Information System is not intended for real-time patient monitoring. The MUSE Cardiology Information System is not intended for pediatric serial comparison. Prescription Use X AND/OR Over-The-Counter Use (Part 21 CFR 801 Subpart D) (Part 21 CFR 1801 Su~bpart C) (PLEASE DO NOT WRITE BELOW THIS LINE - CONTINUE ON ANOTHER PAGE IF NEEDED) Concurrence of CDRH, Office of Device Evaluation (ODE) Owen P.Fas -S 15