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Programme-specific Section of the Curriculum for the MSc Programme in Bioinformatics at the Faculty of Science, University of Copenhagen 2009 (Rev. 2015) Contents 1 Title, affiliation and language... 2 1.1 Title... 2 1.2 Affiliation... 2 1.3 Corps of external examiners... 2 1.4 Language... 2 2 Academic profile... 2 2.1 Purpose... 2 2.2 General programme profile... 2 2.3 General structure of the programme... 2 2.4 Career opportunities... 2 3 Description of competence profiles... 3 3.1 Competence profile... 3 4 Admission requirements... 3 4.1 Applicants with a Bachelor s degree in Natural Sciences and IT... 3 4.2 Applicants with a related Bachelor s degree... 4 4.3 Other applicants... 4 4.4 Language requirements... 4 5 Prioritisation of applicants... 4 6 Structure of the programme... 4 6.1 Programme components... 5 6.2 Compliance of the requirements for external examiners and assessment... 6 7 Exemptions... 6 8 Commencement etc.... 6 8.1 Validity... 6 8.2 Transfer... 6 8.3 Amendment... 7 Appendix 1 Tables... 8 Appendix 2 Interim arrangements... 9 Appendix 3 Description of objectives for the thesis... 11 Page 1 of 11

1 Title, affiliation and language A shared section that applies to all BSc and MSc Programmes at the Faculty of Science is linked to this programme-specific curriculum. 1.1 Title The MSc Programme in Bioinformatics leads to a Master of Science (MSc) in Bioinformatics with the Danish title: Cand.scient. (candidatus/candidata scientiarum) i bioinformatik. 1.2 Affiliation The programme is affiliated with the Study Board for Biomolecular Sciences and Technology, and the students can both elect, and be elected, to this study board. 1.3 Corps of external examiners The following corps of external examiners is used for the central parts of the MSc Programme: Corps of External Examiners for Computer Science (datalogi) with possibility of bringing in examiners from Corps of External Examiners for Biology (biologi). 1.4 Language The language of this MSc Programme is English. 2 Academic profile 2.1 Purpose The MSc Programme in Bioinformatics aims to qualify students to work on an interdisciplinary scientific basis with bioinformatics in both the public and private sectors. 2.2 General programme profile The first the student follow both compulsory courses in bioinformatics and courses that complement their competences from their BSc. Hereby, all students will have competences in both molecular biology (biochemistry and biology) and computer science (mathematics and statistics). In addition, the student follows supplementary courses that prepare them for a specialisation during their thesis thereby creating an individual academic profile. Bioinformatics is the key subject area of the programme. Bioinformatics uses mathematical, statistical and computational techniques in DNA sequence analysis, protein and RNA structural analysis, genomics and analysis of high-output data to solve biological problems. 2.3 General structure of the programme The MSc Programme is set at 120 ECTS credits. There are no defined specialisations in this programme. 2.4 Career opportunities The MSc Programme in Bioinformatics qualifies students for a PhD programme, and depending on the academic specialisation it may also be targeted at business functions and/or areas such as: Pharmaceutical and biotech companies. Hospitals. Research institutions, public and private, and in universities. Page 2 of 11

3 Description of competence profiles Students following the MSc Programme acquire the knowledge, skills and competences listed below. Students will also acquire other qualifications through elective courses and other study activities. 3.1 Competence profile On completion of the programme, an MSc in Bioinformatics has acquired the following: Knowledge about: The fields of biological sequence analysis, molecular phylogeny, structural bioinformatics, systems biology and the bioinformatics aspects of gene expression and proteomics data. A wide range of computer programs used in bioinformatics. Relevant aspects of genetics, molecular biology, cell biology, mathematics, statistics, computer science and machine learning. Bioinformatics scientific literature and knowledge within the subject area. The industrial and medical applications of the subject's results. Skills to: Process, interpret and evaluate large biological datasets. Identify and extract information about complex biological processes as well as computer science and statistical issues. Use information technology, including databases and programs, in an efficient and appropriate manner, and develop small programs. Evaluate and apply techniques described in bioinformatics scientific literature. Communicate knowledge and build bridges in interdisciplinary groups. Competences in: Manage work and development situations that are complex, unpredictable and require new model solutions. Independently initiate and implement academic and interdisciplinary partnerships, and assume professional responsibility. Taking independent responsibility for their own academic development and specialisation. Develop computer programs or scripts for bioinformatics analyses. 4 Admission requirements Students are admitted to the MSc Programme in Bioinformatics once a, with studies starting on 1 September. Applicants with a Bachelor s degree in Science and IT from the University of Copenhagen who complete their Bachelor s degree in block 1 or 2 may additionally be admitted onto the MSc programme in Bioinformatics with studies starting on 1 February of the academic in question. The last time this is possible is in the academic 2015/16. 4.1 Applicants with a Bachelor s degree in Natural Sciences and IT Applicants with a Bachelor s degree in Natural Sciences and IT from the University of Copenhagen are directly academically qualified for admission to the MSc programme. Page 3 of 11

4.2 Applicants with a related Bachelor s degree Applicants with a Bachelor s degree within the field of Science or Technical Science from the University of Copenhagen or other Danish or international universities may also be admitted if their programme includes the following elements: or Courses in molecular biology, genetics and biochemistry corresponding to a minimum of 30 ECTS credits. Courses in statistics, computer science, mathematics and physics corresponding to a minimum of 30 ECTS credits. 4.3 Other applicants The Faculty may also admit applicants who, after a thorough academic assessment, are deemed to possess a Bachelor s degree with educational qualifications equivalent to those required in Subclauses 4.1-2. 4.4 Language requirements 4.4.1 Applicants from Nordic universities Applicants with a Bachelor s degree from Nordic universities must as a minimum document English language qualifications comparable to a Danish upper secondary school English B level. 4.4.2 Non-Nordic applicants Applicants with a non-nordic Bachelor s degree must be able to document English proficiency corresponding to an IELTS test score of minimum 6.5 or a TOEFL test score of minimum 213 (computer-based), 560 (paper-based) or 83 (Internet-based). 5 Prioritisation of applicants If the number of qualified applicants to the programme exceeds the number of places available, applicants will be prioritised as follows: 1) Applicants with a Bachelor s degree in Natural Sciences and IT from the University of Copenhagen seeking admission by way of direct extension of their completed BSc programme. 2) On the basis of the interdisciplinary nature of their education, i.e. priority will be given to applicants whose Bachelor s degree includes courses in biology, mathematics, physics and computer science. 3) Other applicants based on grades and courses taken relevant to bioinformatics. 6 Structure of the programme The compulsory subject elements, restricted elective subjects elements and the thesis constitute the central parts of the programme (Section 21 of the Ministerial Order on Bachelor and Master s Programmes (Candidatus) at Universities). All of the compulsory subject elements (including the thesis) defined below must be followed at the exact time planned according to the table in Appendix 1. and elective subject elements may be freely placed in the remaining blocks. Page 4 of 11

6.1 Programme components The programme is set at 120 ECTS credits and consists of the following: Compulsory subject elements, 30 ECTS credits subject elements, 45 ECTS credits subject elements, 15 ECTS credits Thesis, 30 ECTS credits 6.1.1 Compulsory subject elements All of the following subject elements are to be covered (30 ECTS credits): NBIA05008U Biological Sequence Analysis Block 1 7.5 ECTS credits NBIA05014U Structural Bioinformatics Block 2 7.5 ECTS credits NBIA09043U Population Genetics Block 3 7.5 ECTS credits NBIA07023U Bioinformatics of High Throughput Analysis Block 4 7.5 ECTS credits 6.1.2 subject elements 45 ECTS credits are to be covered as subject elements from the following two lists: 7.5 ECTS credits are to be covered as subject elements from the following list: NBIK14031U Molecular Biology for Non-life Sciences* Block 1 7.5 ECTS credits NBIK14032U Linux and Phython Programming* Block 1 7.5 ECTS credits *One of the two courses must be followed in block 1, 1. 37.5 ECTS credits are to be covered as subject elements from the following list: NBIK10017U RNA Biology Block 1 7.5 ECTS credits NDAK14008U Programming Massively Parallel Hardware Block 1 7.5 ECTS credits NBIK15022U Advanced Topics in Bioinformatics Block 1 7.5 ECTS credits NBIK15017U Theoretical Molecular Genetics Block 1 7.5 ECTS credits NMAK14029U Statistics for Bioinformatics and escience Block 2 7.5 ECTS credits (StatBI/E) NBIK14006U Principles in Genomic Studies Block 2 7.5 ECTS credits NDAA09009U Numerical Optimization Block 2 7.5 ECTS credits NDAK15007U Machine Learning (ML) Block 2 7.5 ECTS credits NDAK15015U Data Analysis Methods (DAM) Block 3 7.5 ECTS credits NDAK10009U Computational Geometry Block 3 7.5 ECTS credits NBIA08011U Statistics for Molecular Biomedicine Block 3 7.5 ECTS credits NDAK14007U Applied Programming (APP) Block 4 7.5 ECTS credits NBIK10005U Bioinformatics Project 1 Block 1-5 7.5 ECTS credits NBIK10008U Bioinformatics Project 2 Block 1-5 7.5 ECTS credits NBIK10009U Bioinformatics Project 3 Block 1-5 7.5 ECTS credits NBIK10010U Bioinformatics Project 4 Block 1-5 7.5 ECTS credits NBIK10012U Individual Project in Bioinformatics Block 1-5 7.5 ECTS credits NBIK10013U Individual Project in Bioinformatics Block 1-5 15 ECTS credits Page 5 of 11

6.1.4 subject elements 15 ECTS credits are to be covered as elective subject elements. BSc subject elements corresponding to 15 ECTS credits may be included in the MSc Programme without the approval of the study board. Projects outside the course scope may be included in the elective section of the programme with up to 15 ECTS credits. The regulations are described in Appendix 5 to the shared section of the curriculum. Projects in practice may be included in the elective section of the programme with up to 15 ECTS credits. The regulations are described in Appendix 4 to the shared section of the curriculum. 6.1.5 Thesis The MSc Programme in Bioinformatics includes a thesis corresponding to 30 ECTS credits, as described in Appendix 2 to the shared curriculum. The topic of the thesis must be within the academic scope of the MSc programme. There are programme specific rules which define parts of the shared curriculum in more detail. The following specific rules apply to this programme: The thesis must be written full time. 6.1.6 Academic mobility The academic mobility for the MSc Programme in Bioinformatics is placed in block 1+2 of the 2 nd. This means that the curriculum makes it possible to follow subject elements and conduct projects outside the Faculty of Science. In addition the student has the possibility to arrange similar academic mobility in other parts of the programme. Both options require that the student acts according to the rules and regulations regarding pre-approvals and credit. 6.2 Compliance of the requirements for external examiners and assessment The MSc Programme automatically fulfils the requirement that one-third of the programme's ECTS credits must be subject to external examination and two-thirds of the ECTS credits must be assessed by grades, cf. the Shared Section of the BSc and MSc Curricula for Study Programmes. ECTS credits transferred are excluded from the calculation of the requirement for external examination and assessment by grades. 7 Exemptions In exceptional circumstances, the university may grant exemptions from the rules in the curriculum specified solely by the university. 8 Commencement etc. 8.1 Validity This subject specific section of the curriculum applies to all students enrolled on the programme see however Appendix 2. 8.2 Transfer Students enrolled on previous curricula may be transferred to the new one as per the applicable transfer regulations or according to an individual credit transfer by the study board. Page 6 of 11

8.3 Amendment The curriculum may be amended once a so that any changes come into effect at the beginning of the academic. Amendments must be proposed by the study board and approved by the Dean. Notification about amendments that tighten the admission requirements for the programme will be published online at www.science.ku.dk one before they come into effect. If amendments are made to this curriculum, an interim arrangement may be added if necessary to allow students to complete their MSc Programme according to the amended curriculum. Page 7 of 11

Appendix 1 Tables Table for students admitted to the programme in September (summer): Table - MSc Programme in Bioinformatics Block 1 Block 2 Block 3 Block 4 Biological Sequence Analysis Structural Bioinformatics Population Genetics Bioinformatics of High Throughput Analysis 1st Molecular Biology for Non-Life Sciences Or Linux and Phyton Programming 2nd Thesis Compulsory... Table for students admitted to the programme in February (winter): Table MSc Programme in Bioinformatics* 1st Block 3 Block 4 Block 1 Block 2 Population Genetics Bioinformatics of High Throughput Analysis Biological Sequence Analysis Molecular Biology for Non-Life Sciences Or Linux and Phyton Programming Structural Bioinformatics 2nd Thesis Compulsory *This table is only relevant for students who begin the MSc Programme in Agricultural Economics in February (block 3) Page 8 of 11

Appendix 2 Interim arrangements The Shared Section of the BSc and MSc Curricula for Study Programmes 2014 (rev. 2015) applies to all students admitted in the academic 2015/16 or earlier. 1 General changes valid for students admitted in the academic 2014/15 or earlier Structure of the programme Students admitted to the MSc Programme in the academic 2014/15 or earlier must finish the programme with the curriculum structure that they were admitted onto, as shown in the table below: Compulsory subject elements, 30 ECTS credits subject elements, 30 ECTS credits subject elements, 30 ECTS credits Thesis, 30 ECTS credits Block 1 Block 2 Block 3 Block 4 1 st Biological Sequence Analysis Structural Bioinformatics Population Genetics Bioinformatics of High Throughput Analysis 2 nd Thesis Compulsory subject elements The former division between special courses and ancillary courses and the maximum of ancillary courses is no longer valid. Therefore, 30 ECTS credits may be freely covered by subject elements from the list of restricted elective subject elements listed in the curriculum for 2015/16. The following subject elements may also count as restricted elective subject element: NBIA04011U Theoretical Molecular Genetics (cancelled) 7.5 ECTS credits NDAA09028U Statistical Methods for Machine Learning (cancelled) 7.5 ECTS credits 1.3 Thesis The thesis may either be carried out as a full-time project at the end of the study programme or concurrently with other subject elements. However, the thesis must conclude the programme. Page 9 of 11

2 General changes valid for students admitted in the academic 2013/14 or earlier subject elements The following courses may count as restricted elective subject element: NBIA05012U Molecular Biology and Genetics (cancelled) 7.5 ECTS credits NBIA06001U Biokemi 2: Protein og nukelinsyre biokemi, molekylær- og cellebiologi (cancelled) 15 ECTS credits 3 Course specific changes valid for students admitted in the academic 2014/15 or earlier Discontinued course Statistical Methods for Machine Learning (NDAA09028U), 7.5 ECTS credits Interim arrangement The course was offered for the last time in 2014/15. From 2014/15 the course has changed title and been replaced by Machine Learning (NDAK15007U), 7.5 ECTS credits Theoretical Molecular Genetics (MolGenTeo) (NBIA04011U), 7.5 ECTS credits The course was offered for the last time in 2014/15. A third examination attempt will be offered in the academic 2015/16. The course has changed from bachelor s level to master s level and is replaced by Theoretical Molecular Genetics (NBIK15017U), 7.5 ECTS credits Page 10 of 11

Appendix 3 Description of objectives for the thesis After completing the thesis, the student should have: Knowledge about: Theory and methods within bioinformatics and the selected specialisation. Suitable combinations of methodologies/theories in bioinformatics based on international research and the strength and limitations of the methods. Formulation and analysis of problems in bioinformatics. A wide range of computer programs used in bioinformatics. Skills to: Select, apply and critically evaluate theories and methods in bioinformatics, including their applicability and limitations. Discuss and communicate issues arising from the thesis in a scientific context. Draw conclusions in a clear and academic manner in relation to the problem formulation and relating it to a broader scientific context. Select and use a wide range of different methods and in silico analyses relevant to their specialization. Use standard and specialised software. Competences to: Initiate and perform a research oriented project independently. Analyse and interpret own results and conclusions based on bioinformatics principles and relate it to other peoples data. Put their own results in scientifically relevant context. Independently develop their knowledge and skills related to bioinformatics and to related areas like computer science and molecular biology. Solve complex problems and assess the quality, relevance and probability of their own and others results. Develop computer programs or scripts for bioinformatics analyses. Page 11 of 11