1. Identification of the substance/preparation and the company/undertaking

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MSDS Check-Direct CPE (Catalog no. 18-0080) 4-Color Compensation Set for Check-Direct CPE (Catalog no. 18-0070) 1. Identification of the substance/preparation and the company/undertaking Product name Supplier Check-Direct CPE; 4-Color Compensation Set for Check-Direct CPE Binnenhaven 5 6709 PD Wageningen The Netherlands Tel: +31 317 453 908 Fax: +31 317 210 147 E-mail: info@check-points.com Emergency telephone number +31 317 453 908 E-mail address of person responsible for this SDS Recommended use info@check-points.com Check-Direct CPE is a rapid molecular assay for the detection of carbapenemases by real-time PCR directly from rectal swabs. 4-Color Compensation Set for Check-Direct CPE is used to generate a color compensation object when the Check-Direct CPE assay is to be performed on the LightCycler 480 system I or II. Remarks A kit contains vials with ready-for-use reagents. 2. Hazards identification This product is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification Human health hazards Environmental hazards Physical/chemical hazards Not classified. Based on the available data of this product no hazardous properties are known. Based on the available data of this product no hazardous properties are known. Based on the available data of this product no hazardous properties are known. Date of issue/revision: August 25 th 2014 Page 1 of 6

3. Composition/information on ingredients Occupational exposure limits, if available, are listed in section 8. 4. First-aid measures Effects and symptoms Inhalation Ingestion Skin contact Eye contact First-aid measures General Inhalation Ingestion Skin contact Eye contact First aid facilities There is no known acute effect after over-exposure to this product. There is no known acute effect after over-exposure to this product. There is no known acute effect after over-exposure to this product. Irritating effects cannot be excluded. Move exposed person to fresh air. If inhaled, remove to fresh air. Obtain medical attention if symptoms occur. If swallowed, rinse mouth with water (only if the person is conscious). Obtain medical attention if symptoms occur. Wash with soap and water. Remove contaminated clothing and shoes. Obtain medical attention if symptoms occur. Rinse with plenty of running water. Obtain medical attention if symptoms occur. No special recommendations. 5. Fire-fighting measures Extinguishing media Small fire Large fire Suitable Suitable Unusual fire/explosion hazards Hazardous thermal decomposition products Non-combustible. Use extinguishing media suitable for surrounding materials. Non-combustible. Use extinguishing media suitable for surrounding materials. No specific hazard. Date of issue/revision: August 25 th 2014 Page 2 of 6

Special fire-fighting procedures Protection of fire-fighters No special measures required. Wear suitable protective clothing. Self-contained breathing apparatus. 6. Accidental release measures Personal precautions Use suitable protective equipment (section 8). Environmental precautions Clean-up Methods Small spill and leak Large spill and leak Prevent entry into sewers, basements or confined areas. Dyke if necessary. Take up with suitable material. Place in a suitable container. Clean up affected area with large amount of water. Absorb spill with inert material (e.g. dry sand or earth) and place in a chemical waste container. Recycle, if possible. Clean up affected area with a large amount of water. Note: see section 8 for personal protective equipment and section 13 for waste disposal. 7. Handling and storage Handling Storage Storage temperature Use with adequate ventilation. Store specific solutions (as indicated the respective product s user manual) in the dark. Store between the following temperatures: -30 C and -20 C. Note: See section 10 for stability and reactivity. 8. Exposure controls/personal protection Occupational exposure limits Engineering measures Hygiene measures None required. However, use of adequate ventilation is good industrial practice. When using, do not eat, drink or smoke. Wash hands after handling compounds and before eating, smoking and using the lavatory and at the end of the day. Personal protective equipment Production scale Date of issue/revision: August 25 th 2014 Page 3 of 6

Respiratory system Skin and body Eyes Hands No special protection is required. In case of insufficient ventilation, wear suitable respiratory equipment. Working clothes. Safety glasses with side shields. Wear suitable gloves. Advice on personal protection is applicable for high exposure levels. Select proper personal protection based on a risk assessment of the actual exposure situation. 9. Physical and chemical properties Physical state Color Odor Flash point Lower explosion limit Upper explosion limit Density (g/cm 3 ) Remarks Liquid. [The test consists of vials filled with various solutions.] Colorless. Odorless. Not available. More detailed information on the physical and chemical properties can be requested from the supplier. 10. Stability and reactivity Stability Stable under recommended storage and handling conditions (see section 7). Conditions to avoid No special recommendations. Materials to avoid No special recommendations. 11. Toxicological information Potential acute health effects Inhalation Ingestion Skin contact Date of issue/revision: August 25 th 2014 Page 4 of 6

Acute toxicity Eye contact Potential chronic health effects Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects Chronic toxicity Carcinogenicity Mutagenicity Teratogenicity Reproductive toxicity 12. Ecological information Environmental effects Aquatic ecotoxicity Persistence/degradability Other adverse effects AOX 13. Disposal considerations Methods of disposal (waste of residues; contaminated packaging) Waste must be disposed of in accordance with national and local environmental regulations. 14. Transport information International transport regulations Date of issue/revision: August 25 th 2014 Page 5 of 6

Regulatory UN number Proper shipping name Class PG* Label Additional information information ADR/RID Class Not regulated. - - - - - ADNR Class Not regulated. - - - - - IMDG Class Not regulated. - - - - - IATA Class Not regulated. - - - - - PG* = Packaging group Attention, please read EMS notations like _E-S_ or _F-D_ as E-S or F-D 15. Regulatory information EU regulations Risk phrases Additional warning phrases According to the EU Directives 67/548/EEC and 1999/45/EC this product does not require labeling with symbols and/or R-phrases. 16. Other information Internal code History SDSCPE2014082503 Date of printing August 25 th 2014 Date of issue August 25 th 2014 Version 3 Notice to reader The statements in this Safety Data Sheet were made to the best of our knowledge and are as accurate as possible. They are given for information only. They do not constitute a contractual guarantee of a product s properties. They must neither be altered nor transferred to other products. The user is responsible for ensuring that appropriate precautions are taken and for satisfying themselves that the data are suitable and sufficient for the product s intended purpose. In case of any uncertainty we advise consulting the supplier or an expert. Training advice Before handling this substance/preparation, the personnel involved should be instructed by means of this safety data sheet. Date of issue/revision: August 25 th 2014 Page 6 of 6