Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors

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1 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Beghetti Maurice Galie Nazzareno - Novartis : Pulmonary hypertension imatinib (2012) - Pfizer : Pulmonary hypertension sildenafil ( ) - Bayer Schering Pharma : Pulmonary hypertension riociguat ( ) - Eli Lilly : Pulmonary hypertension tadalafil ( ) - Actelion : Pulmonary hypertension, Tracleer, Macitentan, Selexipag ( ) - GlaxoSmithKline : pulmonary hypertension Ambrisentan ( ) - Novartis : Pulmonary hypertension riociguat (2013) - GlaxoSmithKline : ambrisentan (2014) - Actelion : no relation to a specific product ( ) - Bayer Schering Pharma : no relation to a specific product ( ) - Eli Lilly : pulmonary hypertension ( ) - Novartis : pulmonary hypertension ( ) - Pfizer : pulmonary hypertension ( ) - Actelion : pulmonary hypertension ( ) - GlaxoSmithKline : pulmonary hypertension ( ) - Bayer AG : pulmonary hypertension ( ) - GSK : Ambrisentan and Tadalafil (2014) - Actelion : macitentan (2014) - Bayer Healthcare : Riociguat ( ) - Pfizer : sildenafil ( ) - GSK : Ambrisentan, Tadalafil, epoprostenol (2015) 1/48

2 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Galie Nazzareno - Actelion : macitentan, bosentan, epoprostenol, selexipag (2015) - Pfizer : pulmonary hypertension ( ) - Actelion : pulmonary hypertension ( ) - GlaxoSmithKline : pulmonary hypertension ( ) - Bayer AG : pulmonary hypertension ( ) - GSK : ambrisentan and Tadalafil ( ) - Bayer Healthcare : riociguat ( ) - Actelion : Selexipag ( ) - Pfizer : sildenafil ( ) Ghofrani Hossein Ardeschir - Novartis : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - Bayer Healthcare : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) - Ergonex : Pulmonary Hypertension (2013) - Gilead : Pulmonary Hypertension ( ) - Merck Sharp & Dohme : Pulmonary Hypertension ( ) - Bellerophon : Pulmonary hypertension (2015) - Pfizer : Pulmonary Hypertension and other lung diseases (2012) - Actelion : Pulmonary Hypertension ( ) 2/48

3 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Ghofrani Hossein Ardeschir - Bayer Healthcare : Pulmonary Hypertension ( ) - Ergonex : Pulmonary Hypertension (2013) - Pfizer : Pulmonary Hypertension ( ) Gibbs Simon - GlaxoSmithKline : Pulmonary hypertension: ambrisentan, Flolan (2012) - Actelion : Pulmonary hypertension: bosentan, macitentan (2012) - Lilly : Pulmonary hypertension: Tadalafil (2012) - United Therapeutics : Pulmonary hypertension: Treprostinil (2012) - Novartis : Trial adjudication Committee member ( ) - Bayer AG : Pulmonary hypertension: riociguat ( ) - Pfizer : Pulmonary hypertension: Sildenafil ( ) - Gilead : Trial Adjudication Committee member ( ) - AOP Orphan Pharmaceuticals : Pulmonary hypertension (2013) - Actelion : Pulmonary hypertension: bosentan, macitentan; Trial adjudication Committee member (2013) - GlaxoSmithKline : Pulmonary hypertension: ambrisentan, epoprostenol ( ) - Actelion : Pulmonary hypertension: bosentan, macitentan; epoprostenol ( ) Gomez Sanchez Miguel Angel - United Therapeutics : Pulmonary hypertension: treprostinil (2012) - GlaxoSmithKline : ambrisentan, tadalafil (2012) - Servier : ivabradine ( ) - Actelion : macitentan ( ) - Bayer Schering Pharma : riociguat ( ) - Ferrer Internacional : treprostinil ( ) 3/48

4 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Hansmann Georg Nothing to be declared ( ) Hoeper Marius M - Novartis : Imatinib (2012) - Lilly : Tadalafil (2012) - GlaxoSmithKline : Ambrisentan ( ) - Actelion : Bosentan, Macitentan ( ) - Bayer AG : Iloprost, Riociguat ( ) - Pfizer : Sildenafil ( ) Humbert Marc - Lilly : Pulmonary Hypertension ( ) - Aires : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension ( ) - Novartis : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) Klepetko Walter Nothing to be declared ( ) Lancellotti Patrizio - Boston Scientific : Heart Failure (2012) 4/48

5 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Lancellotti Patrizio - Servier : Heart Failure (2013) - Abbott : MitraClip (2013) - Menarini : nebivolol (2014) - St Jude Medical : Heart Failure (2015) - Astra Zeneca : Brilique (2012) - Servier : Coversyl (2012) - Abbott Vascular : MitraClip (2012) - Astrazeneca : Dyslipidemia (2013) - Boston Scientific : CRT (2014) - Servier : procoralan (2014) - Daiichi Sankyo : Teaching course on imaging (2015) Lang Irene Marthe - Actelion : Pulmonary Hypertension (2013) - Actelion : Bosentan ( ) - Cordis : Cypher ( ) - Astra Zeneca : Rosiglitazone ( ) - Lilly : Tadalafil, ReoPro ( ) - Merck Sharp & Dohme : Vernakalant ( ) - GlaxoSmithKline : Ambrisentan ( ) - Boehringer-Ingelheim : Dabigatran ( ) - Spectranetics : Laser ( ) - Servier : Procoralan ( ) 5/48

6 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Lang Irene Marthe - Medtronic : Resolute ( ) - Bayer Healthcare : Riociguat ( ) - Boston Scientific : stents ( ) - Biotronik : stents ( ) - United Therapeutics : Treprostinil ( ) - Actelion : Opsumit ( ) - Daiichi Sankyo : Prasugrel ( ) - Astra Zeneca : Rosuvastatin ( ) - Servier : Clarify Registry ( ) - Bayer Healthcare : CTEPH Academy Vienna (2015) - Actelion : Bosentan ( ) - Bayer : research funding ( ) Matucci-Cerinic Marco Nothing to be declared ( ) McDonagh Theresa Peacock Andrew - AbbVie, actelion, gsk, pfizer, bms : rheumatology (2015) - Vifor International : Ferrinject ( ) - Novartis : Honoraria ( ) - Servier : Ivabridine (2012) - Novartis : Heart Failure (2013) - Bayer : pulmonary hypertension ( ) 6/48

7 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Peacock Andrew - Actelion : pulmonary hypertension ( ) - GlaxoSmithKline : pulmonary hypertension ( ) - United Therapeutics : pulmonary hypertension ( ) Pierard Luc - Bayer : pulmonary hypertension ( ) - Siemens Healthcare : Echo machine (2012) - GE Healthcare : Echo machine VIVID (2012) - Bayer Healthcare : Rivaroxaban (2012) - Astra Zeneca : Rosuvastatine, Ticagrelor (2012) - Novartis : Aliskirene (2013) - Astra Zeneca : Rosuvastatin ( ) - Boehringer-Ingelheim : Dabigatran ( ) - Abbott Vascular : MitraClip ( ) - Bristol Myers Squibb : Apixaban (2015) - Boehringer-Ingelheim : Dabigatran (2015) - Abbott : MitraClip (2015) Simonneau Gerald - Astra Zeneca : Rosuvastatine ( ) - Eli Lilly : tadalafil (2012) - Bayer : Iloprost, riociguat ( ) - Pfizer : revatio ( ) - GlaxoSmithKline : ambrisentan ( ) 7/48

8 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Simonneau Gerald - Actelion : bosentan ( ) - Bayer Healthcare : Riociguat ( ) - Actelion : bosentan ( ) - Bayer Healthcare : riociguat ( ) E - Research funding (personal). - GlaxoSmithKline : ambris"entan ( ) - Actelion : bosentan ( ) - Bayer : iloprost, riociguat ( ) Torbicki Adam - Cardiomems : implanted pulmonary artery pressure sensor (2012) - United Therapeutics : Pulmonary arterial hypertension (2012) - Lilly : pulmonary arterial hypertension - tadalafil (2012) - AOP Orphan Pharmaceuticals : Pulmonary arterial hypertension - treprostinil (2012) - Bristol Myers Squibb : thromboembolic disease - Apixaban (2012) - GlaxoSmithKline : pulmonary arterial hypertension - ambrisentan ( ) - Actelion : pulmonary arterial hypertension - macitentan, selexipag ( ) - Bayer Healthcare : pulmonary arterial hypertention - iloprost, riociguat, VTE - xarelto ( ) - Bristol Myers Squibb : Pulmonary arterial hypertension ( ) - Lilly : pulmonary arterial hypertension - ambrisentan ( ) - AOP Orphan Pharmaceuticals : pulmonary arterial hypertension (2015) - Sanofi Aventis : Thromboembolic disease (2012) - Bayer Healthcare : Pulmonary hypertension ( ) 8/48

9 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Trigo Trindade Pedro Nothing to be declared ( ) Vachiery Jean-Luc - Pfizer : Pulmonary Hypertension (sildenafil) (2012) - Eli Lilly : Pulmonary Hypertension (tadalafil) ( ) - GlaxoSmithKline : Pulmonary Hypertension (ambrisentan, epoprostenol) ( ) - Actelion : Pulmonary Hypertension (macitentan, bosentan) ( ) - Bayer Schering Pharma : Pulmonary Hypertension (riociguat, ventavis) ( ) - United Therapeutics : Pulmonary Hypertension (treprostinil) ( ) - Merck Sharp & Dohme : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension (ambrisentan) (2015) - Bayer Schering Pharma : Pulmonary hypertension (riociguat) (2015) - Actelion : Pulmonary Hypertension (selexipag, macitentan) (2015) - United Therapeutics : Pulmonary hypertension (treprostinill) (2015) Vonk Noordegraaf Antonie - Actelion : Pulmonary Hypertension (selexipag, macitentan) (2015) - Bayer Schering Pharma : ricociguat ( ) - Lilly : tardanafil ( ) - United Therapeutics : remodulin ( ) - Pfizer : Revatio ( ) - Actelion : tracleer ( ) - GlaxoSmithKline : Volibris ( ) - Bayer Schering Pharma : riociguat (2015) 9/48

10 Guidelines on Pulmonary Hypertension 2015 (TF08) - Task Force Members and Additional Contributors Zompatori Maurizio Nothing to be declared ( ) 10/48

11 Aboyans Victor Nothing to be declared (2013) - Astra Zeneca : Antithrombotics (2014) - Sanofi Aventis : Hyperlipidemia (2014) - Boehringer-Ingelheim : Oral anticoagulation (2014) - Pfizer/BMS alliance : Oral anticoagulation (2014) - Novartis : Hypertension ( ) - Bayer Healthcare : Oral anticoagulation ( ) - Merck Sharp & Dohme : Antithrombotics (2015) Achenbach Stephan - Bayer : Anticoagulation (2013) - Behring : Anticoagulation (2013) - Astra Zeneca : Antiplatelet Therapy (2013) - Abbott : Coronary Intervention (2013) - Siemens Healthcare : CT (2013) - Servier : Imaging (2013) - Guerbet : Imaging (2013) - Abbott : Coronary Intervention ( ) - Siemens Healthcare : Imaging ( ) Agewall Stefan - Böhringer Ingelheim : Anticoagulatn treatment (2013) - Roche Diagnostics : Cardiac markers (2013) - Orion : Heart failure (2013) 11/48

12 Agewall Stefan - Pfizer : Lipids (2013) - Sanofi Aventis : Lipids (2013) - Siemens Healthcare : Markers (2013) - Astra Zeneca : Platelet inhibition ( ) - Thermo Fischer Scientific : Cardiac markers ( ) Allanore Yannick - BMS : scleroderma (2013) - Biogen : scleroderma (2013) - Actelion : scleroderma ( ) - Sanofi Aventis : scleroderma ( ) - Bayer AG : scleroderma ( ) - Genentech / Roche : scleroderma ( ) - Medac : scleroderma ( ) - Inventiva : scleroderma ( ) - Pfizer : scleroderma, rheumatoid arthritis ( ) - UCB : rheumatoid arthritis ( ) - Actelion : bosentan, macitentan (2015) - Inventiva : fibrosis (2015) - cellgen : fibrosis (2015) - Servier : immunology (2015) - Roche Pharma : immunology (2015) - Pfizer : rheumatoid arthritis (2015) - Bayer Healthcare : riociguat (2015) 12/48

13 Allanore Yannick - Sanofi/Genzyme : scleroderma ( ) - Inventiva : fibrosis (2015) - Pfizer : immunology (2015) - BMS : immunology (2015) E - Research funding (personal). - Servier : scleroderma (2013) - Genentech / Roche : scleroderma (2013) - Inventiva : scleroderma ( ) Andreassen Arne Kristian - United Therapeutics : Remodulin / Pulmonary arterial hypertension ( ) - Actelion : PAH specific drugs ( ) - GlaxoSmithKline : PAH specific drugs ( ) - Bayer : Riociguat ( ) Anton Ly Asteggiano Riccardo Badano Luigi Paolo - Quintiles : Investigator in Phase III Trial to evaluate the efficacy of Ularitide in patients with acute heart failure ( ) - Bayer : Seminar of pulmonary hypertension (2015) - GlaxoSmithKline : Prospective cross-sectional and long-term longitudinal epdemiological study on pulmonary arterial hypertension (PAH) in Estonia ( ) - Chiesi Pharma : Rosuvastatin ( ) - Edwards Lifesciences : Prosthetic valves (2015) - SamsungMedison : Ultrasound (2013) - Edwards Lifesciences : Clinical Event Comittee member ( ) 13/48

14 Badano Luigi Paolo - Sorin Group : Consultancy ( ) - GE Healthcare : Ultrasound ( ) - Edwards Lifesciences : Heart valve prostheses. Clinical Event Comittee member (2015) - Sorin Group : Heart valve prostheses. Consultancy (2015) - Epygon : Start-up, bioprostheses. Advisory board (2015) Barbera Joan Albert - Epygon : Heart valve prostheses (2015) - GE Healthcare : Ultrasound ( ) E - Research funding (personal). - GE Healthcare : Ultrasound (2013) - Almirall Spain : Chronic Obstructive Pulmonary Disease ( ) - Bayer : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - Ferrer Internacional : Pulmonary Hypertension (2015) Bauer Fabrice - Medtronic : cardiac resynchronisation ( ) - Actelion : pulmonary hypertension ( ) 14/48

15 Bauer Fabrice - Daiichi Sankyo : systemic hypertension ( ) - Bayer : Pulmonary Hypertension vasodilatation therapy (2015) - Actelion : Pulmonary Hypertension vasodilatation therapy (2015) - GSK : Pulmonary Hypertension vasodilatation therapy (2015) - Bayer Healthcare : pulmonary hypertension ( ) - GSK : pulmonary hypertension (2014) Bondermann Diana Botnaru Victor Bouvaist Helene - Actelion, United Therapeutics, AOP, Novartis, Pfizer, Bayer Healthcare : Pulmonary hypertension, left heart failure (2013) - Actelion, Bayer Lifesciences, AOP, Pfizer, GSK : pulmonary hypertension, left heart failure ( ) E - Research funding (personal). - Bayer Healthcare : Pulmonary hypertension, left heart failure (2013) - GlaxoSmithKline : asthma treatment (2013) - Berlinchemie : allergy treatment ( ) - Actelion for speaker fees : PAH medication ( ) - Bayer for speaker fees : CTEPH medication (2015) - Actelion for speaker fees : PAH medication (2015) - GSK for speaker fees : PAH medication (2015) Bueno Hector - Biosensors : stent ( ) - BMS/Pfizer : Apixaban (2013) - Roche Pharma : Dalcetrapib (2013) - Novartis : Relaxin (2013) 15/48

16 Bueno Hector - Bayer Healthcare : Aspirin, rivaroxaban ( ) - Sanofi Aventis : Clopidogrel ( ) - Daiichi Sankyo : Prasugrel ( ) - Eli Lilly : Prasugrel ( ) - Astra Zeneca : Ticagrelor ( ) - Novartis : Serelaxin (2014) - Pfizer : Apixaban ( ) - Bristol Myers Squibb : Apixaban ( ) - Servier : ivabradine ( ) - Menarini : Ranolazine ( ) - Abbott : Absorb stent (2015) - Novartis : Serelaxin, ACZ696 (2015) - Ferrer Internacional : Trinomia (polypill) (2015) - Astra Zeneca : Funding of TAN-SNIP observational study. No drugs involved (2015) E - Research funding (personal). - Astra Zeneca : Ticagrelor ( ) Byrne Robert Nothing to be declared (2013) - Boston Scientific : Medical devices ( ) - Biotronik : Medical devices ( ) - B.Braun : Medical devices ( ) Carerj Scipione Nothing to be declared ( ) 16/48

17 Castro Maria Da Graca - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) - Bayer Schering Pharma : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) Chukhrukidze Archil Nothing to be declared ( ) - Bayer Schering Pharma : Pulmonary Hypertension ( ) Cikes Maja - Astellas : Heart transplantation (2013) - Pfizer : Hypertension (2013) - Berlin Chemie AG : Hypertension (2013) - Sanofi Aventis : Hypertension, ACS (2013) - Roche Diagnostics : Heart failure biomarkers (2014) - Novartis : Heart transplant (2014) - Berlin Chemie AG : Ischaemic heart disease (2014) - Bayer : Anticoagulation ( ) - GE Healthcare : Cardiac Ultrasound (2015) - Novartis : Heart Failure (2015) Coghlan John G - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) 17/48

18 Coghlan John G - Endotronix : Endovascular pressure monitoring systems ( ) - Bayer : Pulmonary Hypertension (2015) Coman Ioan Mircea C - Receipt of royalties for intellectual property. - Springer : Medical Education ( ) - Actelion : Pulmonary Hypertension ( ) - Lung Rx : PHT (2013) - Daiichi Sankyo : anticoagulants ( ) - Sanofi Aventis : dyslipidemia ( ) - Amgen Inc : dyslipidemia ( ) - Fournier Laboratories : dyslipidemia ( ) - Novartis : HF ( ) - Lung Rx : PHT (2013) - Daiichi Sankyo : anticoagulants ( ) - Sanofi Aventis : dyslipidemia ( ) - Amgen Inc : dyslipidemia ( ) - Fournier Laboratories : dyslipidemia ( ) - Novartis : HF ( ) - Geneva Romfarm : Pht (2015) De Pauw Michel - Actelion : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension ( ) 18/48

19 De Pauw Michel - Pfizer : Pulmonary Hypertension ( ) Emdin Michele Nothing to be declared ( ) Erol Cetin Falk Volkmar - Servier : Hypertension ( ) - Menarini : Hypertension ( ) - Boston Scientific : Valves (2013) - Edwards Lifesciences : Valves (2013) - Medtronic : valves (2013) - Valtech : Valves (2013) - Berlin Heals : cell modification ( ) - Boston Scientific : heart valves ( ) - Edwards Lifesciences : heart valves ( ) - Medtronic : heart valves ( ) - Aesculap : minimally invasive mitral surgery ( ) - Philips : Imaging ( ) - Heartware : LVAD ( ) Funck-Brentano Christian - Lundbeck : Cardiac safety of an antidepressant (2013) - Actelion : Consulting on the potential developement of a calcium inhibitor (2013) - Pierre-Fabre : Cardiac Safety of non-cardiovasclar products ( ) - Teva Pharmaceutical Industries : DSMB in an oncology phase IIb trial ( ) 19/48

20 Funck-Brentano Christian - Servier : Cardiac safety of non-cardiovascular drugs under development or on the market. Design of phase I/II trials. ( ) - Janssen Belgium : Cardiac safety of non-cardiovascular drugs under development or on the market. Design of phase I/II trials. ( ) - MMV (CH) : Cardiac Saftey of two antimalarial drugs ( ) - Ipsen : Cardiac saftey of a product for cleansing of the colon prior to bowel procedures (2014) - Intracellular Therapies USA : Cardiac Safety of non-cardiovasclar products ( ) - Banook (CRO) : Data and Safety Monitoring Board for an antibody developed in rheumatology ( ) - Bristol Myers Squibb USA : Review of pharmacovigilance cases for an antiviral drug (2015) Gaine Sean - Medco Health Solutions : co-investigator of a phase I study of an iv antiplatelet drug - payment to the hospital (2013) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) - Bayer AG : Pulmonary Hypertension ( ) - Actelion : GRIPHON Clinical Trial (Institution) ( ) - Pfizer : PH (Grant to Hospital): ( ) - GSK : PH/Asthma/COPD: Grant to Hospital ( ) - Bayer AG : Thrombosis and PH (Grant to Hospital) ( ) Giannakoulas George - Novartis : Acute Heart Failure ( ) - Astra Zeneca : Cardiovascular risk ( ) - Menarini : Chronic coronary artery disease ( ) - Bayer : Pulmonary Hypertension ( ) 20/48

21 Giannakoulas George - Actelion : Pulmonary Hypertension ( ) - Pfizer : Chronic Heart Failure, Atrial Fibrillation (2014) - Servier : Chronic coronary artery disease ( ) - MSD : Hyperlipidemia ( ) - Pfizer : Atrial Fibrillation (2015) - Astra Zeneca : Coronary artery disease (2015) - Bayer : Pulmonary Hypertension - Atrial Fibrillation (2015) Gorenflo Matthias Granton John - Actelion : Bosentan ( ) - Bayer Schering Pharma : Iloprost ( ) C - Receipt of royalties for intellectual property. - Pfizer : Sildenafil ( ) - Gore : ASD-Devices (2015) - Ikaria : inhaled Nitric oxide. Member of sterring committee ( ) - Actelion : Pulmonary Hypertension - member of DSMC ( ) - Bayer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - Lilly : Pulmonary Hypertension ( ) - Actelion : Pulmonary hypetension ( ) - Pfizer : Pulmonary Hypertension ( ) 21/48

22 Granton John - Bayer : Pulmonary Hypertension and Chronic Thromboembolic Pulmonary Hypertension (2015) Gumbiene Lina Nothing to be declared ( ) Ibrahimov Firdovsi Nothing to be declared ( ) Iung Bernard - Bayer : rivaroxaban (2013) - Boehringer-Ingelheim : dabigatran ( ) - Edwards Lifesciences : heart valve prosthesis ( ) - Abbott : Mitraclip ( ) Jaaskelainen Pertti - Novartis : serelaxin/heart failure Advisory Board fee ( ) - Boehringer-Ingelheim : speaker fee ( ) - Astra Zeneca : ticagrelor Advisory Board fee; speaker fees ( ) - Roche Pharma : psychiatry ( ) - Shire HGT : psychiatry ( ) - Servier : psychiatry ( ) - Lundbeck : psychiatry (2015) E - Research funding (personal). - Kuopio University Hospital, Department of Medicine : temporary employment as a researcher in 2013 (2013) - Kuopio University Hospital, Department of Medicine : temporary employment as a researcher in 2014 (2014) Jansa Pavel - Actelion : Bosentan, Macitentan ( ) - AOP Orphan Pharmaceuticals : Remodulin ( ) - Bayer Healthcare : Riociguat ( ) - Actelion : Bosentan, Macitentan ( ) 22/48

23 Jansa Pavel - Bayer Healthcare : Riociguat ( ) Karlocai Kristof - Actelion : Bosentan, Macitentan ( ) - AOP Orphan Pharmaceuticals : Remodulin ( ) - Pfizer : Revatio ( ) - Actelion : Tracleer ( ) - GlaxoSmithKline : Volibris, Flolan ( ) - Lilly : Adcirca ( ) - Bayer Healthcare : Adempas ( ) - Actelion : Tracleer ( ) Kaymaz Cihangir Nothing to be declared ( ) Kiely David G - Bayer Healthcare (Only Institutional payment without any payment to me) : Pulmonary Hypertension, Advisory Board (2015) - Bayer : Pulmonary embolism and pulmonary hypertension (2013) - Actelion Pharmaceuticals : Pulmonary Hypertension (2013) - GSK : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension and Pulmonary Embolism ( ) - Bayer : Imaging and pulmonary hypertension (2013) - Actelion : Pulmonary Hypertension ( ) - Bayer : Pulmonary Hypertension ( ) 23/48

24 Kirchhof Paulus - Otsuka Pharmaceuticals Development and Commercialization (consultancy) : cardiovascular (2013) - Boehringer-Ingelheim : cardiovascular ( ) - Daiichi Sankyo : cardiovascular ( ) - Medtronic : cardiovascular ( ) - Pfizer : cardiovascular ( ) - St Jude Medical : cardiovascular ( ) - Sanofi Aventis : cardiovascular ( ) - Meda pharma : cardiovascular ( ) - Bristol Myers Squibb : cardiovascular ( ) - Merck Sharp & Dohme : cardiovascular ( ) - Medscape : cardiovascular ( ) - Bayer Healthcare : cardiovascular (2015) - Correvio : cardiovascular (2015) - Remedica : cardiovascular (2015) - Boehringer-Ingelheim : cardiovascular (2013) - Bayer Healthcare : cardiovascular (2013) - Gilead : cardiovascular (2013) - BMS / Pfizer alliance : cardiovascular (2013) - St Jude Medical : cardiovascular ( ) - Sanofi Aventis : cardiovascular ( ) - Meda pharma : cardiovascular ( ) 24/48

25 Kirchhof Paulus - Daiichi Sankyo : cardiovascular ( ) - British Heart Foundation : cardiovascular ( ) - BMS / Pfizer alliance : cardiovascular ( ) - Leducq Foundation : cardiovascular ( ) - European Union FP7 : cardiovascular ( ) - European Union horizon2020 : cardiovascular ( ) - German Centre for Heart Research (DZHK, funded by German Ministry of Education and Research) : cardiovascular ( ) Kjellstrom Barbro Nothing to be declared ( ) Kurzyna Marcin - Actelion : pulmonary hypertension ( ) - GlaxoSmithKline : pulmonary hypertension ( ) - AOP Orphan Pharmaceuticals : pulmonary hypertension ( ) - Bayer Healthcare : pulmonary hypertension, thrombosis ( ) - Pfizer : pumonary hypertension ( ) - Sanofi Aventis : thrombosis ( ) Landmesser Ulf - Sanofi Aventis : thrombosis ( ) - Roche Pharma : Cardiovascular Research (2013) - Amgen : Advisory Board, Speakers fee ( ) - Sanofi Aventis : Advisory Board, Speakers fee ( ) - MSD : Advisory Board, Speakers fee ( ) - Roche Pharma : Research grant, Advisory Board ( ) 25/48

26 Landmesser Ulf - Pfizer : Research grant, Speakers fee ( ) - St. Jude : Advisory Board (2015) Lazareva Irina - Servier : arterial hypertension (2013) - Actelion : macitentan (SERAPHIN OL) (2014) - Actelion : macitentan (SERAPHIN OL), selexipag (GRIPHON OL) (2015) - Actelion : pulmonary hypertension, sub-investigator in trials SERAPHIN, GRIPHON (2013) Lebrun Frederic Nothing to be declared (2015) - Actelion : macitentan (SERAPHIN OL) (2014) - Bayer Healthcare : Rivaroxaban ( ) - Boehringer-Ingelheim : Dabigatran (2014) Lekakis John - Pfizer : HEART FAILURE (2013) - Astra Zeneca : HYPERLIPIDEMIA (2013) - MSD : Inegy ( ) - Actelion : Macitentan ( ) - Menarini : RANOLAZINE ( ) - Bayer : RIVAROXABAN ( ) - Astra Zeneca : ROSUVASTATIN ( ) Lionis Christos - Amgen : Speaker fees (2013) - GlaxoSmithKline : Speaker fees (2013) - Pfizer Hellas : Speaker fees (2013) 26/48

27 Lionis Christos - Spring to Life Ltd : Teaching fees (2015) - Leo Pharma : consultancy fees (2014) - MSD : speaker fees (2014) - UCB : speaker fees (2014) - Vianex : speaker fees (2014) - APR : speaker fees (2014) - Pfizer International Operations : speaker fees (2014) - GlaxoSmithKline : teaching fees (2014) Lip Gregory Y H - Pfizer : Community acquired pneumonia epidemiological research study. No product or therapeutic area. (2013) - Astellas : atrial fibrillation, thrombosis (2013) - Biotronik : atrial fibrillation ( ) - Boehringer-Ingelheim : atrial fibrillation, thrombosis ( ) - Daiichi Sankyo : atrial fibrillation, thrombosis ( ) - Pfizer : atrial fibrillation, thrombosis ( ) - Bayer Healthcare : atrial fibrillation, thrombosis ( ) - Bristol Myers Squibb : atrial fibrillation, thrombosis ( ) - Medtronic : atrial fibrillation ( ) - Roche Diagnostics : anticoagulation (2015) - Bayer : atrial fibrillation, thrombosis (2013) - Daiichi Sankyo : atrial fibrillation, thrombosis ( ) 27/48

28 Mahdhaoui Abdallah Nothing to be declared ( ) Menachemi Doron Nothing to be declared ( ) - Novartis : Heart Failure Treatment (2015) Micallef Josef Nothing to be declared ( ) Moiseeva Olga - Bayer Healthcare : pulmonary hypertension ( ) - Actelion : pulmonary hypertension (2015) - GlaxoSmithKline : pulmonary hypertension (2015) - Actelion : pulmonary hypertension ( ) - Bayer Healthcare : pulmonary hypertension ( ) - Servier : Heart Failure ( ) Moutiris Joseph Antoniou Nothing to be declared ( ) Myftiu Sokol Nothing to be declared ( ) Nielsen-Kudsk Jens Erik - St Jude Medical : Interventional Cardiology (consultant) ( ) - Bayer : Pulmonary Hypertension (advisory board) ( ) - Actelion : Pulmonary Hypertension (speeker fee) ( ) - GSK : Pulmonary Hypertension (speeker fee) (2015) - Gore : Interventional Cardiology (investigator) ( ) Oddsson Hjortur Nothing to be declared ( ) - Bayer : Pulmonary Hypertension (investigator) ( ) - Actelion : Pulmonary Hypertension (Investigator) ( ) 28/48

29 Opitz Christian - Bayer : Pulmonary Hypertension ( ) - Novartis : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) Orfanos Stylianos - Actelion : Pulmonary Hypertension ( ) - Actelion : pulmonary arterial hypertension ( ) - United Therapeutics : pulmonary arterial hypertension ( ) - Pharmaserve Lilly : pulmonary arterial hypertension ( ) - Bayer : pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension ( ) - Novagem : pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (2015) - Actelion : pulmonary arterial hypertension ( ) - Pfizer : pulmonary arterial hypertension (RCT & research) and pulmonary fibrosis (research) (2013) - Bayer : pulmonary arterial hypertension (RCT) ( ) - GlaxoSmithKline : pulmonary arterial hypertension (RCT) ( ) - United Therapeutics : pulmonary fibrosis (research) ( ) - Pfizer : pulmonary arterial hypertension (RCT) (2014) Oukerraj Latifa Nothing to be declared ( ) - United Therapeutics : pulmonary arterial hypertension (RCT) (2015) Park Myung H - Bayer : PAH medication ( ) 29/48

30 Park Myung H - United Therapeutics : PAH medication ( ) - Gilead : PAH medication ( ) - Actelion : PAH medications ( ) - Bayer : PAH Therapeutics (2015) - Actelion : PAH Therapeutics (2015) - United Therapeutics : PAH Therapeutics (2015) - Gilead : PAH Therapeutics (2015) - Bayer : PAH therapies ( ) - Actelion : PAH therapies ( ) - United Therapeutics : PAH therapies ( ) - Gilead : PAH therapies ( ) - Actelion : PAH Therapeutics (2015) Piepoli Massimo Francesco Nothing to be declared ( ) Ponikowski Piotr - Bayer : anticoagulant (2013) - Bristol Myers Squibb : anticoagulant (2013) - ROSCHE : diabetes (2013) - Boehringer-Ingelheim : anticoagulant ( ) - Respicardia : anticoagulant ( ) - Johnson & Johnson : heart failure ( ) - Pfizer : heart failure, anticoagulant ( ) - Abbott Vascular : devices ( ) 30/48

31 Ponikowski Piotr - Novartis : heart failure ( ) - Cardiorentis : heart failure ( ) - Bayer Healthcare : heart failure ( ) - Vifor Pharma ltd : heart failure ( ) - CIBIEM : heart failure ( ) - Servier : heart failure, coronary artery disease ( ) - Amgen : heart failure, lipids ( ) - MSD : lipids (2014) - Astra Zeneca : acute coronary syndrome ( ) - Boehringer-Ingelheim : anticoagulant, diabetes (2015) - Respicardia : devices (2015) - BioControl : devices (2015) - DC Device : devices (2015) - Celladon : heart failure (2015) - Vifor Pharma ltd : heart failure (2014) - MSD : lipids (2014) - Astra Zeneca : acute coronary syndrome ( ) - Respicardia : anticoagulant ( ) - Novartis : heart failure ( ) - Cardiorentis : heart failure ( ) - Bayer Healthcare : heart failure ( ) - CIBIEM : heart failure ( ) 31/48

32 Ponikowski Piotr - Servier : heart failure, coronary artery disease ( ) - Amgen : heart failure, lipids ( ) - BioControl : devices (2015) - DC Device : devices (2015) - Celladon : heart failure (2015) - Vifor Pharma ltd : heart failure (2013) - Singulex : biomarkers (2015) Revel Marie-Pierre Nothing to be declared ( ) Ribeiro Leite Baptista Maria Joao Nothing to be declared ( ) Rigau David Nothing to be declared ( ) Rosenkranz Stephan - Actelion : Pulmonary Hypertension ( ) - GlaxoSmithKline : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) - Pfizer : Pulmonary Hypertension, Anticoagulants ( ) - Novartis : Pulmonary Hypertension, Heart Failure ( ) - Bayer : Pulmonary Hypertension, Heart Failure, Anticoagulants ( ) - BMS : Anticoagulation ( ) - Bayer : Pulmonary Hypertension ( ) - Actelion : Pulmonary Hypertension ( ) - United Therapeutics : Pulmonary Hypertension ( ) 32/48

33 Rosenkranz Stephan - AOP Orphan Pharmaceuticals : Pulmonary Hypertension ( ) Rudzitis Ainars Nothing to be declared (2013) - Novartis : Pulmonary Hypertension, Heart Failure ( ) - Sequel Pharmaceutics : Arterial hypertension (2014) - Servier : Arterial Hypertension (2015) - Shire HGT : Pulmonary Hypertension (2015) Schwerzmann Markus - Actelion : Pulmonary hypertension ( ) - Bayer Healthcare : Pulmonary hypertension (2014) - Actelion : Pulmonary hypertension ( ) - Bayer Healthcare : Pulmonary hypertension (2015) Simkova Iveta - GlaxoSmithKline : ambrisentan (2013) - Pfizer : eplerenon, sildenafil, apixaban (2013) - Bayer : rivaroxaban ( ) - AOP Orphan Pharmaceuticals : treprostinil ( ) - Servier : arterial hypertension ( ) - Merck Serono : bisoprolol ( ) - Actelion : bosentan ( ) - Pfizer : apixaban (2014) - Bayer : riociguat (2015) Sirenko Yuriy - Takeda Pharmaceuticals : Azilsartan ( ) 33/48

34 Sirenko Yuriy - Pfizer : Cardiovascular (2015) - Servier : Cardiovascular (2015) - Sanofi Aventis : Cardiovascular (2015) - Menarini : Cardiovascular (2015) - Takeda Pharmaceuticals : Cardiovascular (2015) - Servier : perindopril+amlodipine+indapamide ( ) - Pfizer : amlodipine + atorvastatin (2014) Sokolovic Sekib Nothing to be declared ( ) Sooronbaev Talant Nothing to be declared ( ) Srbinovska-Kostovska Elizabeta Nothing to be declared ( ) Stefanovic Branislav Nothing to be declared ( ) van Dijk Arie - Servier : Prexanor (2014) - Actelion : Pulmonary arterial hypertension treatment ( ) - Pfizer : PAH treatment ( ) - Actelion : PAH-treatment ( ) Vaz Carneiro Antonio Nothing to be declared (2015) Velchev Vasil - AbbVie : Oncology ( ) - Boston Scientific : Inetrventional cardiology ( ) - Astra Zeneca : Ticagrelor, Crestor ( ) 34/48

35 Velchev Vasil - Servier : Trimetazidine, Ivabradine ( ) Voller Heinz Nothing to be declared ( ) Wikstrom Bernt Gerhard - The German pension insurance : Government of technician and science (2013) - Novartis : Heart failure (2013) - Servier : Heart Failure (2013) - Actelion : PAH (2013) - Bayer AG : Pulmonary Hypertension (2013) - GSK : pulmonary hypertension (2013) - Pfizer : cardiac amyloidosis ( ) - Novartis : Heart failure ( ) - Actelion : PAH ( ) - GSK : PAH ( ) - GE Healthcare : Heart failure (2015) - Servier Pharmaceutics : Heart Failure (2015) - Bayer Healthcare : PAH, CTEPH (2015) Zamorano Gomez Jose Luis - Uppsala University : PAH (2013) - Daiichii : Atrial Fib (2013) - Merck Sharp & Dohme : Lipid Lowering (2013) - Philips : 3D echo (2014) - Toshiba medical imaging : fusion imaging 3D echo CT (2014) 35/48

36 Zamorano Gomez Jose Luis - Astra Zeneca : Speaker fee for 1 talk in 2014 (2014) - MSD : CV risk factors ( ) - Abbott : Lecturing (2015) - Astra Zeneca : Lecturing (2015) - Pfizer : Lecturing (2015) - Sorin Group : Respicardia echo protocol (2015) - European Research FP7 : CV Imaging (2013) - Servier : Imaging in ISchemic patients (2013) - Siemens Healthcare : 3d echo software and free style echo ( ) - Toshiba medical imaging : Fusion Imaging (2015) C - Receipt of royalties for intellectual property. - Springer : ESC Textbook of CV Imaging (2013) - Amgen : Clinical trial ( ) - Novartis : Clinical trial ( ) - Ikaria : Clinical trial ( ) 36/48

37 Committee for Practice Guidelines MEMBERS Aboyans Victor Nothing to be declared (2013) - Astra Zeneca : Antithrombotics (2014) - Sanofi Aventis : Hyperlipidemia (2014) - Boehringer-Ingelheim : Oral anticoagulation (2014) - Pfizer/BMS alliance : Oral anticoagulation (2014) - Novartis : Hypertension ( ) - Bayer Healthcare : Oral anticoagulation ( ) - Merck Sharp & Dohme : Antithrombotics (2015) Achenbach Stephan - Bayer : Anticoagulation (2013) - Behring : Anticoagulation (2013) - Astra Zeneca : Antiplatelet Therapy (2013) - Abbott : Coronary Intervention (2013) - Siemens Healthcare : CT (2013) - Servier : Imaging (2013) - Guerbet : Imaging (2013) - Abbott : Coronary Intervention ( ) - Siemens Healthcare : Imaging ( ) Agewall Stefan - Böhringer Ingelheim : Anticoagulatn treatment (2013) - Roche Diagnostics : Cardiac markers (2013) - Orion : Heart failure (2013) 37/48

38 Committee for Practice Guidelines MEMBERS Agewall Stefan - Pfizer : Lipids (2013) - Sanofi Aventis : Lipids (2013) - Siemens Healthcare : Markers (2013) - Astra Zeneca : Platelet inhibition ( ) - Thermo Fischer Scientific : Cardiac markers ( ) Badimon Lina - Astra Zeneca : cardiovascular (2013) - Sanofi Aventis : cardiovascular (2013) - MSD-España : Lipids (2014) - Sanofi Aventis : lipids ( ) - Burson Masteller : nutrition ( ) - Astra Zeneca : thrombosis ( ) Baron Esquivias Gonzalo - Astrazeneca : thrombosis ( ) - Bayer : Anticoagulation ( ) - Boehringer-Ingelheim : Anticoagulation ( ) - Daiichi Sankyo : Anticoagulation ( ) - Pfizer : Anticoagulation ( ) - Menarini : Ischemic disease (2015) - Laboratorios Rovi : Ivabradine (2015) - Biotronik : Vasovagal syncope & Pacing (2013) - Bayer : Anticoagulation (2015) 38/48

39 Committee for Practice Guidelines MEMBERS Baumgartner Helmut - Actelion : Bosentan and Macicentan for PAH treatment in congenital heart disease ( ) - St. Jude Medical : Occluders for shunt closure (ASD, PFO, PDA, VSD) ( ) - Abbott : transcather mitral valve repair (Mitraclip) ( ) - Edwards Lifesciences : transcatheter valve implantation ( ) - Direct Flow Medical : transcatheter valve implantation ( ) - Actelion : Bosentan for PAH treatment in congenital heart disease ( ) Bax Jeroen Nothing to be declared ( ) - St. Jude Medical : Occluders for shunt closure (ASD, PFO, PDA, VSD) ( ) - Abbott : transcather mitral valve repair (Mitraclip) ( ) - Edwards Lifesciences : transcatheter valve implantation ( ) - Direct Flow Medical : transcatheter valve implantation ( ) - Servier : Farma (2013) - Edwards Lifesciences : Heart Valves (2013) - GE Healthcare : Imaging (2013) - Lantheus Inc : Imaging (2013) - Boston Scientific : Pacing (2013) - Medtronic : Pacing (2013) - St Jude Medical : Pacing (2013) - Biotronik : Pacing (2013) Bueno Hector - BMS/Pfizer : Apixaban (2013) 39/48

40 Committee for Practice Guidelines MEMBERS Bueno Hector - Roche Pharma : Dalcetrapib (2013) - Novartis : Relaxin (2013) - Bayer Healthcare : Aspirin, rivaroxaban ( ) - Sanofi Aventis : Clopidogrel ( ) - Daiichi Sankyo : Prasugrel ( ) - Eli Lilly : Prasugrel ( ) - Astra Zeneca : Ticagrelor ( ) - Novartis : Serelaxin (2014) - Pfizer : Apixaban ( ) - Bristol Myers Squibb : Apixaban ( ) - Servier : ivabradine ( ) - Menarini : Ranolazine ( ) - Abbott : Absorb stent (2015) - Novartis : Serelaxin, ACZ696 (2015) - Ferrer Internacional : Trinomia (polypill) (2015) - Astra Zeneca : Funding of TAN-SNIP observational study. No drugs involved (2015) E - Research funding (personal). - Astra Zeneca : Ticagrelor ( ) Carerj Scipione Nothing to be declared ( ) Erol Cetin - Servier : Hypertension ( ) - Menarini : Hypertension ( ) 40/48

41 Committee for Practice Guidelines MEMBERS Fitzsimons Donna Nothing to be declared ( ) - Amgen : FH Tratment options (2014) Gaemperli Oliver Nothing to be declared (2013) - Biosensors : Stents (2014) - Biosensors : Axxess Bifurcation Stent (2015) - Abbott Vascular : MitraClip (2015) - Biosensors : Travel Grant to AsiaPCR 2015 (2015) Kirchhof Paulus - Otsuka Pharmaceuticals Development and Commercialization (consultancy) : cardiovascular (2013) - Boehringer-Ingelheim : cardiovascular ( ) - Daiichi Sankyo : cardiovascular ( ) - Medtronic : cardiovascular ( ) - Pfizer : cardiovascular ( ) - St Jude Medical : cardiovascular ( ) - Sanofi Aventis : cardiovascular ( ) - Meda pharma : cardiovascular ( ) - Bristol Myers Squibb : cardiovascular ( ) - Merck Sharp & Dohme : cardiovascular ( ) - Medscape : cardiovascular ( ) - Bayer Healthcare : cardiovascular (2015) - Correvio : cardiovascular (2015) - Remedica : cardiovascular (2015) 41/48

42 Committee for Practice Guidelines MEMBERS Kirchhof Paulus - Boehringer-Ingelheim : cardiovascular (2013) - Bayer Healthcare : cardiovascular (2013) - Gilead : cardiovascular (2013) - BMS / Pfizer alliance : cardiovascular (2013) - St Jude Medical : cardiovascular ( ) - Sanofi Aventis : cardiovascular ( ) - Meda pharma : cardiovascular ( ) - Daiichi Sankyo : cardiovascular ( ) - British Heart Foundation : cardiovascular ( ) - BMS / Pfizer alliance : cardiovascular ( ) - Leducq Foundation : cardiovascular ( ) - European Union FP7 : cardiovascular ( ) - European Union horizon2020 : cardiovascular ( ) Kolh Philippe H 2015) - German Centre for Heart Research (DZHK, funded by German Ministry of Education and Research) : cardiovascular ( B.Braun : Surgical instruments ( ) - Astra Zeneca : Antiplatelet agents ( ) - St Jude Medical : Cardiac valves (2013) - Boston Scientific : Coronary stents (2013) - Siemens Healthcare : Medical imaging (2013) - Johnson & Johnson : Thoracoscopic devices (2013) 42/48

43 Committee for Practice Guidelines MEMBERS Kolh Philippe H - Edwards Lifesciences : Cardiac valves ( ) - Medtronic : Cardiac valves ( ) Lancellotti Patrizio - Servier : Heart Failure (2013) - Abbott : MitraClip (2013) - Menarini : nebivolol (2014) - St Jude Medical : Heart Failure (2015) - Astrazeneca : Dyslipidemia (2013) - Boston Scientific : CRT (2014) - Servier : procoralan (2014) - Daiichi Sankyo : Teaching course on imaging (2015) Lip Gregory Y H - Actelion : Pulmonary Hypertension (2013) - Astellas : atrial fibrillation, thrombosis (2013) - Biotronik : atrial fibrillation ( ) - Boehringer-Ingelheim : atrial fibrillation, thrombosis ( ) - Daiichi Sankyo : atrial fibrillation, thrombosis ( ) - Pfizer : atrial fibrillation, thrombosis ( ) - Bayer Healthcare : atrial fibrillation, thrombosis ( ) - Bristol Myers Squibb : atrial fibrillation, thrombosis ( ) - Medtronic : atrial fibrillation ( ) - Roche Diagnostics : anticoagulation (2015) 43/48

44 Committee for Practice Guidelines MEMBERS Lip Gregory Y H - Bayer : atrial fibrillation, thrombosis (2013) - Daiichi Sankyo : atrial fibrillation, thrombosis ( ) Nihoyannopoulos Petros Nothing to be declared ( ) - GSK : Consultant for Imaging studies (2013) Piepoli Massimo Francesco Nothing to be declared ( ) Ponikowski Piotr - Bayer : anticoagulant (2013) - Bristol Myers Squibb : anticoagulant (2013) - ROSCHE : diabetes (2013) - Boehringer-Ingelheim : anticoagulant ( ) - Respicardia : anticoagulant ( ) - Johnson & Johnson : heart failure ( ) - Pfizer : heart failure, anticoagulant ( ) - Abbott Vascular : devices ( ) - Novartis : heart failure ( ) - Cardiorentis : heart failure ( ) - Bayer Healthcare : heart failure ( ) - Vifor Pharma ltd : heart failure ( ) - CIBIEM : heart failure ( ) - Servier : heart failure, coronary artery disease ( ) - Amgen : heart failure, lipids ( ) - MSD : lipids (2014) 44/48

45 Committee for Practice Guidelines MEMBERS Ponikowski Piotr - Astra Zeneca : acute coronary syndrome ( ) - Boehringer-Ingelheim : anticoagulant, diabetes (2015) - Respicardia : devices (2015) - BioControl : devices (2015) - DC Device : devices (2015) - Celladon : heart failure (2015) - Vifor Pharma ltd : heart failure (2014) - MSD : lipids (2014) - Astra Zeneca : acute coronary syndrome ( ) - Respicardia : anticoagulant ( ) - Novartis : heart failure ( ) - Cardiorentis : heart failure ( ) - Bayer Healthcare : heart failure ( ) - CIBIEM : heart failure ( ) - Servier : heart failure, coronary artery disease ( ) - Amgen : heart failure, lipids ( ) - BioControl : devices (2015) - DC Device : devices (2015) - Celladon : heart failure (2015) - Vifor Pharma ltd : heart failure (2013) - Singulex : biomarkers (2015) 45/48

46 Committee for Practice Guidelines MEMBERS Roffi Marco - Daiichi Sankyo : antiplatelet therapy (2013) - Lilly : antiplatelet therapy (2013) - Astra Zeneca : antipletelet therapy (2013) - Johnson & Johnson : coronary catheters (2014) - Biosensors : devices ( ) - Boston Scientific : devices ( ) - Medtronic : devices ( ) - Biotronik : devices ( ) - Abbott Vascular : devices ( ) Torbicki Adam - Bristol Myers Squibb : Pulmonary arterial hypertension ( ) - GlaxoSmithKline : pulmonary arterial hypertension - ambrisentan ( ) - Lilly : pulmonary arterial hypertension - ambrisentan ( ) - Actelion : pulmonary arterial hypertension - macitentan, selexipag ( ) - Bayer Healthcare : pulmonary arterial hypertention - iloprost, riociguat, VTE - xarelto ( ) - AOP Orphan Pharmaceuticals : pulmonary arterial hypertension (2015) - Bayer Healthcare : Pulmonary hypertension ( ) Vaz Carneiro Antonio Nothing to be declared (2015) Windecker Stephan - AbbVie : Oncology ( ) - Astra Zeneca : Antiplatelet drug (2013) - Eli Lilly : Antiplatelet drug (2013) 46/48

47 Committee for Practice Guidelines MEMBERS Windecker Stephan - Abbott : Stent (2013) - Medtronic : Stent (2013) - Biotronik : Stent (2013) - Astra Zeneca : Antiplatelet therapy ( ) - Eli Lilly : Antiplatelet therapy ( ) - Bayer Healthcare : Antithrombotic drug ( ) - Abbott : Stent and Heartvalvetherapy ( ) - Biosensors : Stents ( ) - Boston Scientific : Stents ( ) - Medtronic : TAVI, Stent (2015) - Edwards Lifesciences : Transcatheter heart valves (2015) - St Jude Medical : OCT ( ) - Biotronik : Stent ( ) - Medtronic : Stent and Heartvalves (2014) - Medicines Company : Antithrombotic therapy ( ) - Johnson & Johnson : Catheters ( ) - Edwards Lifesciences : Heartvalves ( ) - Abbott : Stent ( ) - Boston Scientific : Stent and Heartvalves ( ) Zamorano Gomez Jose Luis - Daiichii : Atrial Fib (2013) - Merck Sharp & Dohme : Lipid Lowering (2013) 47/48

48 Committee for Practice Guidelines MEMBERS Zamorano Gomez Jose Luis - Philips : 3D echo (2014) - Toshiba medical imaging : fusion imaging 3D echo CT (2014) - Astra Zeneca : Speaker fee for 1 talk in 2014 (2014) - MSD : CV risk factors ( ) - Abbott : Lecturing (2015) - Astra Zeneca : Lecturing (2015) - Pfizer : Lecturing (2015) - Sorin Group : Respicardia echo protocol (2015) - European Research FP7 : CV Imaging (2013) - Servier : Imaging in ISchemic patients (2013) - Siemens Healthcare : 3d echo software and free style echo ( ) - Toshiba medical imaging : Fusion Imaging (2015) C - Receipt of royalties for intellectual property. - Springer : ESC Textbook of CV Imaging (2013) - Amgen : Clinical trial ( ) - Novartis : Clinical trial ( ) - Ikaria : Clinical trial ( ) 48/48

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