Price List. Initial consultation (up to 60 minutes) includes pelvic ultrasound scan (if required). 195

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1 Price List Consultation Initial consultation (up to 60 minutes) includes pelvic ultrasound scan (if required). 195 Initial consultation (up to 60 minutes) and semen analysis includes pelvic 250 ultrasound scan (if required). Follow up consultation (up to 30 minutes). 100 Follow up consultation (after more than one year). Includes scan & semen analysis. 175 IVF / ICSI & IUI outcome review (within 3 months of treatment). Fertility Assessments Ovarian Reserve Testing (female biological clock test) 175 Includes AMH blood test and ultrasound for antral follicles. Specialist Consultations Recurrent Miscarriage 195 Includes pelvic ultrasound if required. Excludes blood investigations. Premature Menopause 195 Includes pelvic ultrasound scan if required. Excludes blood investigations Paediatric and Adolescent Gynaecology Includes pelvic ultrasound if required. Excludes blood investigations. 195 Treatments Inclusive In-Vitro Fertilisation (IVF) Package 2895 Fee Includes: Treatment planning All ultrasound scans in treatment cycle HFEA license fee Sedation for egg collection Ultrasound guided egg recovery Blastocyst culture Assisted Hatching (if indicated) Embryo transfer Embryo vitrification Embryo freezing and one year storage Review consultation (if within three months of end of treatment) Two pregnancy scans (six and nine weeks) The cost of drugs for ovarian stimulation ( depending on dose)

2 Donor sperm, if needed Intracytoplasmic Sperm Injection (ICSI) Package 3595 IVF package as above & ICSI In-Vitro Fertilisation (IVF) 3 CYCLE Package Fee 5790 excludes: The IVF cost package of drugs as above for ovarian stimulation ( depending on dose) Intracytoplasmic Sperm Injection (ICSI) 3 CYCLE Package Intracytoplasmic 7190 Morphologically Selected Sperm Injection (IMSI) 295 IVF package as above and ICSI All 3-cycle packages must be completed within 1 year of purchase. An abandoned cycle before egg collection IVF is package counted as as a cycle above of & treatment. ICSI The package is considered fulfilled at 20 weeks of The cost of drugs for ovarian stimulation ( depending on dose) In-Vitro Fertilisation (IVF) 3 CYCLE Package* 5790 IVF package as above Available as a package from 31/3/12 Intracytoplasmic Sperm Injection (ICSI) 3 CYCLE Package* 7190 IVF package as above and ICSI Available as a package from 31/3/12 * All 3 cycle packages must be completed within 1 year of purchase. An abandoned cycle before egg collection is counted as a cycle of treatment. The package is considered fulfilled at 20 weeks of pregnancy or following 3 completed cycles IVF Lite Package (minimal stimulation IVF) 2995 IVF package as above and ICSI Drugs IVF Converted to ICSI on Day of Treatment 700 Cancelled IVF / ICSI BEFORE EGG COLLECTION (refund) 1895 / 2595 IVF conversion to IUI (if poor ovarian response and IUI appropriate) refund Donor Egg Programme Egg Sharing Egg Provider: Includes: All ultrasound scans in treatment cycle Counselling session Treatment planning HFEA license fee

3 All drugs Sedation for egg recovery Ultrasound guided egg recovery Blastocyst culture Embryo transfer Embryo vitrification Embryo freezing and one year storage Review consultation (if within three months of the end of treatment) Two pregnancy scans (six and nine weeks) Excludes: Assisted hatching (if required) ICSI treatment (if required) Donor sperm (if required) Egg Recipient (of egg sharer) 5895 The cost of drugs (donor and recipient) All ultrasound scans in treatment cycle ICSI treatment if required Counselling session HFEA license fee Blastocyst culture Assisted Hatching (if indicated) Embryo transfer Embryo vitrification Embryo freezing for first year (if applicable) Review consultation (if within three months of the end of treatment) Two pregnancy scans (six and nine weeks) Fee excludes Donor sperm (if needed) Donor Egg Cycle (With Known Donor or Partner-Partner Donation) 495 Cost of additional scans (for 2 people) Cost of IVF / ICSI cycle Donor Egg Cycle (CRGW in conjunction with IVI, Valencia) Donor Egg Cycle (With Imported Frozen Eggs) POA POA Frozen Embryo Transfer Frozen Embryo Transfer Medicated Cycle 795 Treatment discussion, drugs, ultrasound scans, embryo thawing and transfer, HFEA fee.

4 Frozen Embryo Transfer Natural Cycle 395 Treatment discussion, ultrasound scans, LH sticks, embryo thawing and transfer, HFEA fee. Intrauterine Insemination (IUI) Procedures Stimulated IUI 595 Treatment discussion, ultrasound scans, semen assessment, preparation and insemination. Drugs (average cost is around 200) Donor IUI 595 Treatment discussion, ultrasound scans, semen assessment, preparation and insemination. Cost of donor sperm Drugs (average cost is around 200) Stimulated IUI- Three Cycle Package 1400 Treatment discussion, ultrasound scans, semen assessment, preparation and insemination. Drugs (average cost is around 200 per cycle) IUI Follicle Reduction 300 Discussion, sedation, follicle aspiration IUI converted to IVF 2000 IVF package as above.

5 Laboratory Procedures Assisted Hatching (if indicated) Blastocyst Culture Embryo vitrification and storage for first year Embryo storage (yearly fee after first year) 275 IVF converted to ICSI on treatment day 700 Semenology Semen analysis 75 Semen analysis & consultation with Embryologist 125 Sperm DNA fragmentation test & semen analysis 425 Semen freezing including one year of storage 200 Semen storage (annually after one year) 275 Sperm washing for HIV including preparation, freezing, viral screening 400 and courier charges Sperm Y-Chromosome micro-deletion screening & semen analysis 295 Sperm aneuploidy (5 chromosome test) & semen analysis 595 Sperm DNA fragmentation plus aneuploidy & semen analysis 795 Surgical Sperm Retrieval Surgical sperm retrieval (PESA/TESA) with sedation 1000 includes all fees, freezing and first year of storage. Payable if sperm retrieved or not. Surgical sperm retrieval (PESA/TESA/MESA) under general anaesthetic 3000 includes all fees, freezing and first year of storage. Payable if sperm retrieved or not. Ultrasound scans Pelvic ultrasound scan 95 Early Pregnancy scan if not current patient at CRGW (6-12 weeks) 75 Pregnancy Dating Scan (12-16 weeks) 75 Pregnancy Sexing Scan (from 18 weeks) 75 Pregnancy Growth Scan (24-34 weeks) 75 Presentation Scan (34 weeks to 42 weeks) 50

6 Additional Pregnancy scan for CRGW patient 50 Follicular tracking and endometrial scan if not CRGW patient 50 4D baby bonding scan (performed from weeks gestation) 95 Includes DVD and black and white scan prints (Multiple Pregnancies scanned from weeks) Additional Procedures Priming and hiring of dry shipper (free for patients importing to CRGW) 250 Courier charge for exporting embryos including administration fee 200 Courier charge for exporting sperm including administration fee 200 Ultrasound aspiration of ovarian cyst 200 Trial embryo transfer (non CRGW patient) 195 Free for patients undergoing IVF / ICSI at CRGW Egg Freezing (Fertility Preservation) 2450 All ultrasound scans in treatment cycle HFEA license fee Sedation for egg recovery Ultrasound guided egg recovery Egg Vitrification First year storage Cost of drugs for ovarian stimulation Investigations and Procedures Hysterosalpingogram (HSG) performed by Consultant Radiologist 250 HyCosy ultrasound assessment of tubal patency 225 Diagnostic laparoscopy and dye test Hysteroscopy POA POA Endometrial biopsy for natural killer (NK) cells 395 Intralipid infusion 250

7 Blood Tests AMH 70 Anti cardiolipin 60 BHcG 30 Blood group 30 Chlamydia (swab or urine test) 40 Chromosomes 150 Cystic fibrosis gene 180 CMV (blood test) 30 Full blood count 25 FSH 25 Gonorrhoea (swab or urine) 40 HIV/Hepatitis B/Hepatitis C (plus syphilis when required) 100 HTLV 1&2 100 High vaginal swab 30 LH 25 Lupus DDRV 50 MSU 15 Prolactin 40 Progesterone 30 Rubella 30 Testosterone 25 Thrombophilia screen 180 Thyroid function 35 Administration Charges Request for copy of medical records 25 Preparation of medical reports 50 Foreign visa letter requests 30 Letter 25 Failure to attend follow up consultation (if less than 24 hours notice) 75 Drug Prices Menopur 75 IU 17 Menopur 600 IU 136 Menopur 1,200 IU 272 Puregon 300 IU 125 Puregon 600 IU 230 Gonal F 300 IU pen 95 Gonal F 450 IU pen 140 Gonal F 900 IU pen 280 Suprecur 5.5 ml 20 Cetrotide 0.25 mg 25 Cetrotide 0.25 mg x Cetrotide 3 mg 150 Pregnyl 5000 IU 5.00

8 Ovitrelle 6500 IU 12 Cyclogest 400 mg pessary (for 15) 15 Gestone 50 mg 7.50 Gestone 50 mg (for 16 days) 120 Crinone 8% Gel 1.50 Oestridiol 2 mg x 84 tablet pack 15 Norestherone 5 mg 0.15 Prednisolone 5 mg 0.15 Clexane 20 mg 5.00 Refund Policy Occasionally treatment cycles have to be cancelled due to a variety of reasons. If this occurs the refund due will be as follows: IVF Cancelled IVF before egg collection 1895 No eggs recovered at egg collection 500 No embryo transfer (failed fertilisation) 250 IVF converted to IUI 1800 ICSI Cancelled ICSI before egg collection 2595 No eggs recovered at egg collection 1000 No eggs suitable for injections 1000 No embryo transfer (failed fertilisation) 250 IUI Stimulated IUI during monitoring 295 Unstimulated IUI during monitoring 95 FET During monitoring 300 No embryo transfer (failed thaw) 200 This fee schedule is effective from 26th March 2012 and supersedes all previous prices. It may be subject to change without notice. Please check website for up to date prices. Centre for Reproduction & Gynaecology Wales (CRGW) Ely Meadows Rhodfa Marics Llantrisant CF72 8XL Tel: Fax:

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