Program of the ESPGHAN Hepatology Summer School 2010
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1 Program of the ESPGHAN Hepatology Summer School 2010 Organized by: ESPGHAN Hepatology Committee Date: 13-16th May 2010 Venue: Hotel Campanile - Cracow,, Poland Local organizer: Prof. Piotr Socha The Children s Memorial Health Institute Department of Gastroenterology, Hepatology and Immunology Al. Dzieci Polskich Warsaw, Poland p.socha@czd.pl 1
2 ESPGHAN Hepatology Committee Dhawan (London) Piotr Socha (Warsaw) Florence Lacaille (Paris) Lorenzo D Antiga (Bergamo) Emmanuel Jacquemin (Paris) Paloma Jara (Madrid) Patrick Mc Kiernan (Birmingham) Ozlem Durmaz (Istanbul) Pietro Vajro (Naples) Faculty Members of the ESPGHAN Hepatology Summer School 2010 Paediatric hepatology: Dhawan (London) Piotr Socha (Warsaw) Florence Lacaille (Paris) Lorenzo D Antiga (Bergamo) Ekkehard Sturm Patrick Mc Kiernan (Birmingham) Ozlem Durmaz Suoglu (Istanbul) Pietro Vajro (Naples) Joanna Pawlowska (Warsaw) Liver transplant and surgery: Piotr Kalicinski (Warsaw) Liver pathology: Alex Knisely (London) Interventional radiology: John Karani (London) 2
3 Microscopic imaging of the liver - what kind of SCIENTIFIC PROGRAM Day May Session 1. information we can obtain (normal liver, fatty liver, cholestasis)? Alex Functions of the liver Patrick Hepatomegaly Florence Abnormal liver tests - the clinical significance Workshop Presentations of the participants: A. Trebst No title. Hypertransaminasemia. M. Mtegha Crigler-Najjar syndrome. Case report? J. Jahnel Lymphocyte subpopulations in MDR2 (ABCB4) knockout mice as model for sclerosing cholangitis. (2x) P. Witters ADP-degrading enzymes inhibit platelet activation in bile-duct ligated rats. C. Prell Autoimmune pancraeatitis with liver involvement. S. Heissat - Making the diagnosis of perinatal hemochromatosis. Pietro Day May Session 2. Acute and chronic hepatitis Acute hepatitis (infectious, toxic, ischaemic) Florence Diagnosis and treatment of HBV Lorenzo Diagnosis and treatment of HCV
4 Pietro Autoimmune hepatitis and sclerosing cholangitis Lorenzo Session 3. Metabolic liver diseases Clinical presentations of metabolic diseases Patrick Approach to the fatty liver: NAFLD Wilson disease Piotr Mitochondrial disorders Patrick Session 4. Cholestatic liver disease Pathophysiology of cholestasis Ekkehard Approach to a jaundiced infant- with emphasis on extrahepatic cholestasis Joanna Inherited cholestatic disorders Ekkehard Workshop Radiology: Ultrasound imaging of the normal liver Tumors- ultrasound, CT scanning Bile ducts- ultrasound, NMR, HIDA scanning (different pathologies- PSC, biliary atresia etc.) Portal hypertension, Budd-Chiari- Doppler, CT Case presentations: cholestasis Cholestasis: Abdoon H - Bile acid synthetic defects in Saudi Arabia. 7 cases. 4
5 B. Andreassen Jaundice in a 2 month old baby. M. Bozo Role of scintigraphy in the diagnosis of biliary atresia in developing countries. P. Witters A rare case of neonatal cholestasis: NISCH syndrome. A. Deutschmann Hepatobiliary transporter expression in children with cholstatic liver disease. M. Basso Eosinophilic cholangitis: a new entity of sclerosing cholangitis, management and outcome at 1 year. Day May Session 5. Complications of chronic liver disease and prehepatic block Medical complications of chronic liver disease (ascites, hepato-renal syndrome, malnutrition) Ozlem Management of children with prehepatic and intrahepatic block Lorenzo (how poor is the evidence) Endoscopic and surgical therapy of portal hypertension Piotr Kalicinski&Patrick Discussion: a surgeon, a hepatologist and all participants Session 6. Acute liver failure Acute liver failure diagnostic approach depending on age Indications for LTx Ozlem Medical management of acute liver failure Pietro Interactive discussion Lunch in the Old Market Square
6 Session 7. Liver transplantation Chronic liver disease - indications for LTx Ozlem How to list a child for LTx - clinical and lab evaluations needed, vaccinations... Joanna The surgical techniques for liver transplantation in children. Piotr Kalicinski Immunosuppression and its complications Florence Graft dysfunction Therapy of a chronic liver disease and after LTx compliance Joanna&Piotr Workshop Case presentations Tumors: AJ. Terblanche Massive hepatic hemangiomendothelioma and severe pulmonary hypertension in a 7 month old child: a case report. A. Kowalski Inflammatory myofibroblastic tumor of liver. Case report. Radiology: E. Kyrana 8 year old girl with congenital portocaval shunt. A. Rybak Liver fibrosis due to subcardiac inferior caval vein stenosis. Case report. Portal hypertension: Vuletic B - Congenital hepatic fibrosis. Case reports. Day May Session 8. Hot topics in paediatric hepatology 6
7 Hepatocyte transplantation What is new in metabolic and autoimmune diseases- shared EU projects and other important projects Scientific writing: originality, methods used. Presentation and panel discussion exemplified Case presentations LTx: P. Czubkowski Non-surgical approach to biliary complications after liver transplantation in children M. Bosisio Management of hepatopulmonary syndrome in children. A single centre report. S. Almeida PTLD experience in a pediatric liver transplant unit. Piotr&Lorenzo&&Pietro&Patrick Piotr Synthesis of presentations & discussions Evaluations and closing remarks. 7
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