Master the elements. Unleash your potential.
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1 Master the elements. Unleash your potential. Until now, traditional sterilization methods have restricted your potential. With superior compatibility across a wider range of materials, the REVOX method is changing that.
2 MATERIALS COMPATIBILITY GUIDANCE Information within this material compatibility guide is not intended to provide a rationale for the use of materials without proper qualification of materials. The information is intended only as a guide to successful material qualification. compatibility guidance Specific materials Thermoplastics Acrylonitrile butadiene styrene (ABS) No change No change after >10 cycles. Polytetrafluoroethylene (PTFE) No change No change after >30 cycles. Perfluoroalkoxy (PFA) No change No change after >30 cycles. Polychlorotrifluoroethylene (PCTFE) No change No change after >10 cycles. Polyvinyl fluoride (PVF) No change No change after >30 cycles. Polyvinylidene fluoride (PVDF) No change No change after >30 cycles. Ethylene tetrafluoroethylene (ETFE) No change No change after >10 cycles. Fluorinated ethylene propylene (FEP) No change No change after >30 cycles. Polyacetals (e.g., polyoxymethylene) No change No change after >30 cycles. Polyacrylates (e.g., polymethylmethacrylate) No change No changes in extractable/ leachable after 4 cycles. Polyamides (e.g., nylon) No change No change after >10 cycles. Styrene-acrylonitrile (e.g., SAN) No change No change after >10 cycles. High density polyethylene (HDPE) No change No change after >30 cycles. Low density polyethylene (LDPE) No change No change after >4 cycles. Tygon No change No change after >10 cycles. Polycarbonate (PC) No change No change after >30 cycles. Polyesters, saturated No change No change after >30 cycles. Polyethylene (PE) No change No change after >30 cycles. Polyimides (e.g., polyetherimide) No change No change after >30 cycles. Polyketones (e.g., polyetheretherketone) No change No change after >30 cycles. Polypropylene (PP) natural No change No change after >30 cycles. Polypropylene (PP) stabilized No change No change after >30 cycles. Polystyrene (PS) No change No change after >10 cycles. Polysulfones No change No change after >30 cycles. Polyurethane (PU) No change No change after >10 cycles. Grade dependent for dehydrogenation cycles only. Polyvinyl acetates (PVA) No change No change after >10 cycles. Polyvinyl chloride (PVC) No change No change after >30 cycles. PVC, plasticized No change No change after >30 cycles. Polyetheretherketone (PEEK) No change No change after >10 cycles. Polyethylene terephthalate (PET) No change No change after >30 cycles. Ethyl vinyl acetate (EVA) No change Weight change after 10 cycles, device tested was foam. Indicates absorption.
3 compatibility guidance Specific materials (continued) Thermosets Phenolics No change No change after >10 cycles. Polyester, unsaturated No change Peak deletion in FTIR observed after 10 cycles. Polyimides (Kapton) No change No change after >10 cycles. Polyurethanes No change No change after >10 cycles. Adhesives Acrylic No change No change after >10 cycles. Epoxy (non-peroxide cured) Recommend the use of peroxide cured epoxy. Fluoroepoxy Methacrylate No change No change after >30 cycles. Urethane acrylate No change No change after >30 cycles. Silicone No change No change after >30 cycles. Ethyl 2 cyanoacrylate (Loctite 4061) No change No change after >10 cycles. Elastomers Butyl Ethylene propylene diene monomer (EPDM) No change No change after >30 cycles. Natural rubber No change Peak deletion in FTIR after 10 cycles. Nitrile No change No change after >30 cycles. Polyacrylic No change No change after >30 cycles. FKM to Dependent on material grade to Viton to Dependent on material grade to Dependent on material grade. Dependent on material grade. Silicone No change No change after >30 cycles. Kalrez No change No change after >10 cycles. Pebax No change Peak deletion in FTIR observed after 10 cycles. Styrenic block copolymers (e.g., styrene-butadiene-styrene, styrene-ethylene-butylene-styrene) Peak deletion in FTIR Neoprene rubber Peak removed in FTIR observed Peak deletion in FTIR observed after 10 cycles. Peak deletion in FTIR observed after 10 cycles. Urethane No change No change after >10 cycles. Grade dependent. For depyrogenation cycles only. Polydimethylsiloxane (PDMS), uncured No change No change after >10 cycles.
4 compatibility guidance Specific materials (continued) Metals (E.4.3) Aluminum Bare (7075) No change No change after >30 cycles. Aluminum Alloy Black Anodize (5056) Slight change After >10 cycles, black Aluminum Bare (1100) Slight change Slight change. Aluminum Alloy Black Anodize (1100) Slight change After >10 cycles, black Aluminum Bare (2024) Slight corrosion observed Corrosion observed. Aluminum Alloy Black Anodize (6061) No change After >10 cycles, black Aluminum Bare (6061) No change After >10 cycles, black Aluminum Alloy Black Anodize (5056) Slight change After >10 cycles, black Brass (464) No change No change after >10 cycles. Copper (CA-110) No change Slightly dull after >10 cycles. Gold No change No change after >30 cycles. Magnesium Slight color change Corrosion observed after 5 cycles. Nickel No change No change after >30 cycles. Silver No change Slight color change after >10 cycles. Stainless steel (304) No change No change after >30 cycles. Stainless steel (316) No change No change after >30 cycles. Stainless steel (430) No change No change after >30 cycles. Mild Steel Corrosion observed Corrosion observed. Hastelloy No change No change after >30 cycles. Nitinol No change No change after >10 cycles. Titanium (Grade 2) No change No change after >30 cycles. Chromium No change No change after >10 cycles.
5 compatibility guidance Specific materials (continued) Ceramics/glasses Aluminum oxides No change New peaks in FTIR observed after 10 cycles. Silica No change No change after >30 cycles. Zirconium oxides No change No change after >10 cycles. Bioabsorbables Tissue and proteins No change after >2 cycles Poly(lactic-co-glycolic acid) (PLGA) [Class 6 implantable] Not tested above 2 cycles No change No change after >10 cycles. Poly(lactic-acid) (PLA) [class 6 implantable] No change No change after >10 cycles. Polyglycolic acid (PGA) No change No change after >10 cycles. Other s Acrylic (acrylate polymer) No change No change after >10 cycles. Cellulosics No change No change after >10 cycles. Printed battery power source No change in voltage nor performance after >2 cycles Not tested above 2 cycles Printed circuit boards No change No change after >30 cycles. Brushed electric motor No change after >2 cycles Not tested above 2 cycles NOTE REVOX Sterilization Solutions provided the information in this table based on unpublished studies conducted in a REVOX Sterilization System. All polymers tested used the following measurements: mass, dimensions, and Fourier transform infrared spectroscopy (FTIR) scans. All metals tested used the following measurements: mass, dimensions, and ASTM-G31-72 (corrosion test).
6 MAKE IT POSSIBLE. Products Tested Enzyme sensors (glucose sensors) ATP filters (depyrogenation required) Complex tubing sets Blood filters Hemostats Lyophilized proteins Stem cell culture plates Synthetic ligaments Surgical drapes Stents Inflatable prosthetics Fiber optics Silver-coated products Hydrogel Insulin pumps Syringes Drug coatings Heart valves Pre-filled syringes Vials Wound care applicators Microbial culture plates Injectable adhesives Injectable drugs Injectable hormones Combination devices Balloon catheters Catheters Wet decellularized porcine tissue Dry collagen wound dressings Bovine tissue Human tissue Goggles Incontinence devices Wound dressings Artificial joints Surgical markers Needles Surgical tools Endoscope valves Ablation devices Pressure sensors Crime scene materials Electronics Tested Batteries Alkaline Lithium Lithium ion Nickel metal hydride Lithium ion polymer Electrical connectors Electric motors Brushed Brushless RFID tags Fiber optic lights Printed circuit boards Flexible circuits 2015 Mar Cor Purification Inc.. All Rights Reserved. PN /A REVOX and Make it possible. are registered trademarks of Mar Cor Purification Inc., A Cantel Medical Company REVOX Sterilization Solutions th Avenue North Minneapolis, MN 55447
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