Resolve Foundational Issues First Diet Signs and symptoms associated with female endocrine problems:

Transcription

1 Primary FDM Testing of Sex Hormones S/Sx of Female Endocrine Dysfunction Resolve Foundational Issues First Diet Signs and symptoms associated with female endocrine problems: PMS Menstrual irregularities Endometriosis Fibroids Weight gain Menopause 1

2 ESTROGEN DOMINANCE Hair loss Headaches Hypoglycemia Increased blood clotting Infertility Irregular menstrual periods Insomnia Memory loss Mood swings PMS Ovarian cysts Pre-menopausal bone loss Sluggish metabolism Thyroid dysfunction Uterine cancer Uterine fibroids Water retention and bloating Speeds up the aging process Weight gain around middle Allergies Autoimmune disorders Breast cancer Breast tenderness Cold hands and feet as a symptom of thyroid dysfunction Decreased sex drive Muscle and joint pain Depression Dry eyes Early onset of menstruation Uterine cancer Fat gain in abdomen, hips, and thighs Fatigue Fibrocystic breasts Foggy thinking S/Sx of Male Endocrine Dysfunction Prostate problems Difficulty with urination, dribbling Difficult to start and stop urine stream Pain or burning with urination Waking to urinate at night Interruption of stream during urination Pain on inside id of legs or heels Feeling of incomplete bowel evacuation Decreased sexual function 2

3 Functional P.E.: Chapman s Reflexes Chapman s Reflexes for prostate and ovaries Tenderness in the area lateral to the pubic symphisis on the rami attachment of the Rectus abdominus muscle tenderness in the middle portions of the right and left ITBs on the lateral thigh Functional Blood Chemistry Analysis 3

4 Serum Estradiol Testing Estradiol- Reference Ranges Normal reference range: Men: <54 pg/ml Women: pg/ml Optimal reference range: Men: pg/ml Women pg/ml 4

5 Low Estradiol in Women Increased risk of osteoporosis and vertebral fracture Endogenous levels l of serum estradiol and sex hormone binding globulin determine bone mineral density, bone remodeling, the rate of bone loss, and response to treatment with estrogen in elderly women Rapuri PB, Gallagher JC, Haynatzki G. J Clin Endocrinol Metab Oct;89(10): ) ) Migraine Headaches High Estradiol in Women Increased risk of breast and endometrial cancer The Asian Advantage How the body handles estrogens is far more important than the amount of estrogen Soy, Vegetables, and Green Tea 5

6 Estradiol and Men Low levels of estradiol are associated with vertebral fractures in older men, but not women: the Rancho Bernardo Study. Barrett-Connor E, Mueller JE, von Muhlen DG, et al J Clin Endocrinol Metab Jan;85(1): Estradiol and Men Estradiol plays a role in promoting the development of atherogenic lipid milieu in men with coronary artery disease. Tivesten A, Hulthe J, Wallenfeldt K, et al. Circulating estradiol is an independent predictor of progression of carotid artery intimamedia thickness in middle-aged men. J Clin Endocrinol Metab Nov;91(11):

7 Serum Free Testosterone Free Testosterone- Reference Ranges Normal reference range: Men: pg/ml Women: pg/ml Optimal reference range: Men: pg/ml Women: pg/ml 7

8 Low Testosterone Levels in Men Diminished libido and erectile dysfunction Metabolic syndrome: Loss of muscle tone and increased abdominal fat Low bone density Depression Alzheimer s disease Low testosterone as a major cardiac risk factor Age, HDL levels, and free testosterone Increased risk of stroke Heart failure Increased glycation Testosterone- an increased risk of prostate cancer? 8

9 Importance of testosterone in Women Muscle strength Bone mass Sexual function Mood Body composition Serum Prostate Specific Antigen (PSA) 9

10 PSA- Reference Ranges Normal reference range: ng/ml or µg/l Optimal reference range: ng/ml or µg/l Baseline testing and PSA Velocity PSA- Some New Evidence PSA may promote prostate cancer PSA s contribution to disease progression & metastasis PSA and Obesity 10

11 Other Primary Bio-Markers For Prostate Cancer PAP Prolactin D-Dimer Fibrinogen Interleukin-6 and CRP Fasting Insulin Blood Testing Panels Female Blood chemistry screen Haemotology Screen DHEA Free testosterone TSH Estradiol Male Blood chemistry screen CBC DHEA Free testosterone TSH PSA Estradiol 11

12 SUMMARY 12