Multiflux-2 Interfaces
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1 Unit 1, Anglian Business Park, Orchard Road, Royston, Hertfordshire, SG8 5TW, UK T: +44 (0) F: +44 (0) E: W: Dolomite Microfluidics North America Office Blacktrace Inc, 29 Albion Place Charlestown, MA 02129, USA C: T: F: E: Multiflux-2 Interfaces product datasheet page Description 2 Main Benefits 3 Specification 3 Cross-sectional View of Sealing Interface 5 Geometry 6 Chip Design Guide 11 Flow Accessories 12 Custom Options 12 The Dolomite Centre Limited Page 1 of 13
2 Part name Part number Top Interface 7-way (4mm) Top Interface 7-way (2mm) Double Top Interface 7-way (4mm) Triple Top H Interface (45mm) H Interface 7-way (11.5mm) H Interface 7-way (22.5mm) H Interface 7-way (45mm) Double Flow Splitting Manifold 7-way Description Multiflux-2 Interfaces work in conjunction with Multiflux-2 Linear Connectors providing fast, reliable and precise fluidic connections from tubing to glass microfluidic chips. The Multiflux-2 range is optimised for microfluidic experimentation offering a multi-way tubing connection with excellent alignment, low dead volume and high density. Top Interfaces enable connection to ports in the top surface of microfluidic chips and are available for 2mm and 4mm chip heights. H Interfaces enable connection to the edge of microfluidic chips providing a straight fluidic path from tubing to microchannel and are available for 4mm chip heights with 11.5mm, 22.5mm and 45 mm chip lengths. The Triple Top H interface combines surface and edge connections. Top: Left; Top Interface 7-way (4mm) (Part No ), Centre; Double Top Interface 7-way (4mm) (Part No ), Right; Triple Top H Interface (45mm) (Part No ) Bottom: Left; 2 x Linear Connector 7-way (Part No ) with Double Top Interface 7-way (4mm) (Part No ) and glass microfluidic chip, Centre; 2 x Linear Connector 7-way (Part No ) with H Interface 7-way (22.5mm) (Part No ) and glass microfluidic chip, Right; H Interface 7-way (45mm) (Part No ) MAR Page 2 of 13
3 Main Benefits High density of connections Micro-scale alignment of flow paths Low dead volume Quick connect/disconnect High pressure capability Excellent chemical compatibility Robust design Specification Specification (when used with compatible 7-way connector) Triple Top H interface (45mm) (Part No ) Double Top Interface 7-way (4mm) (Part No ) Top Interface 7-way (4mm) (Part No ) Top Interface 7-way (2mm) (Part No ) Number of ports Pitch between ports Dead volume Chip thickness options Chip width options 1.5mm <0.05µl per port 4mm (+ 0.2mm / mm) 15mm (+ 0.02mm / - 0.2mm) 2mm (+ 0.2mm / mm) Chip length options 45mm (+ 0.2mm / -0.05mm) 20 90mm 10 90mm Outside diameter of connection tubing Inside diameter of connection tubing Connection tubing material Operating pressure Operating temperature of connector Operating temperature of fluid in connector Wetted materials 0.8mm (1/32inch) 0.1mm, 0.25mm FEP or PEEK 30bar* -15 to 50ºC** -15 to 150ºC *** FEP or PEEK (tubing), FKM (seal), Glass (chip) Connector and interface materials *Based on tests at 21ºC PPS, Stainless Steel, Aluminium, FKM **Upper temperature limit applies to PEEK tubing. FEP tubing is limited to 40ºC ***Assumes external surfaces of connector are at room temperature and tube I.D. <0.3mm MAR Page 3 of 13
4 Specification (when used with compatible 7-way connector) H Interface 7-way (11.25mm) (Part No ) H Interface 7-way (22.5mm) (Part No ) H Interface 7-way (45mm) (Part No ) Number of ports 14 Pitch between ports Dead volume Chip thickness options Chip width options Chip length options Outside diameter of connection tubing Inside diameter of connection tubing Connection tubing material Operating pressure Operating temperature of connector Operating temperature of fluid in connector Wetted materials Connector and interface materials *Based on tests at 21ºC 11.25mm (+ 0.2 mm / -0.05mm) 1.5mm <0.05µl per port 4mm (+ 0.1 mm / - 0.1mm) 15mm (+ 0.02mm / - 0.2mm) 22.5mm (+ 0.2 mm / -0.05mm) 0.8mm (1/32inch) 0.1mm, 0.25mm FEP or PEEK 30bar* -15 to 50ºC** -15 to 150ºC *** FEP or PEEK (tubing), FKM (seal), Glass (chip) PPS, Stainless Steel, Aluminium, FKM **Upper temperature limit applies to PEEK tubing. FEP tubing is limited to 40ºC 45mm (+ 0.2 mm / -0.05mm) ***Assumes external surfaces of connector are at room temperature and tube I.D. <0.3mm. MAR Page 4 of 13
5 Cross-sectional View of Sealing Interface Cross-sectional View of Sealing Interface with Top Interface Connector tubing (FEP) Connector body (PPS) Seal (FKM) Hole through top layer Glass microfluidic chip Microchannel Cross-sectional View of Sealing Interface with H Interface Seal (FKM) Glass microfluidic chip Connector tubing (FEP) Microchannel Connector body (PPS) MAR Page 5 of 13
6 Geometry Top Interface 7-way (4mm) with Linear Connector 7-way (Part No ) Top Interface 7-way (2mm) with Linear Connector 7-way (Part No ) MAR Page 6 of 13
7 Double Top Interface 7-way (4mm) with 2 x Linear Connector 7-way (Part No ) MAR Page 7 of 13
8 H Interface 7-way (11.25mm) with 2 x Linear Connector 7-way (Part No ) H Interface 7-way (22.5mm) with 2 x Linear Connector 7-way (Part No ) MAR Page 8 of 13
9 H Interface 7-way (45mm) with 2 x Linear Connector 7-way (Part No ) MAR Page 9 of 13
10 Triple Top H Interface (45mm) with 3 x Linear Connector Funnel (Part No ) and Linear Connector 7-way (Part No ) MAR Page 10 of 13
11 Chip Design Guide A compatible chip can be designed for use with Multiflux-2 interfaces by following the design rules given below for chip geometry and port position. Required geometry and port positions of top surface connection chip Top Interface 7-way (4mm) or Top Interface 7-way (2mm) Double Top Interface 7-way (4mm) Required geometry and port positions of edge connection chip H Interface 7-way (11.5mm), H Interface 7-way (22.5mm) or H Interface 7-way (45mm) MAR Page 11 of 13
12 Flow Accessories The Double Flow Splitting Manifold 7-way works in conjunction with the Double Top Interface 7-way (4mm) (Part No ) and 2 x Linear Connector 7-way (Part No ) to provide a simple flow splitting solution for lab experimentation. Each groove in the surface of the manifold can be used to split 1 inlet flow into 6 equal outlet flows. The manifold is manufactured from PEEK offering excellent chemical resistance. 2 Input Lines 6 Output Lines 6 Output Lines 2 x Linear Connector 7-way (Part No ) Double Flow Splitting Manifold 7-way (Part No ) in Double Top Interface 7-way (4mm) (Part No ) Top Left: Double Flow Splitting Manifold 7-way (Part No ) Centre: Connection from 0.8 mm OD tubing to Double Flow Splitting Manifold 7-way (Part No ) using the Double Top Interface 7-way (4mm) (Part No ) and 2 x Linear Connector 7-way (Part No ) Custom Options Dolomite is a world leader in microfluidic connectors and can offer custom connection systems for individual applications. The range of Dolomite services available covers all aspects of the development process from concept studies and feasibility testing to the design of commercial instruments. Please contact Dolomite to discuss your application. MAR Page 12 of 13
13 MAR Page 13 of 13
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