Oxford Nanomedicine Summer School 29 June 3 July Nanotechnologies for Medicine and Healthcare

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1 Oxford Nanomedicine Summer School 29 June 3 July 2015 Nanotechnologies for Medicine and Healthcare University of Oxford, Ewert House, Summertown OX2 7DD Introduction to Nanomedicine; Challenges and Opportunities Monday 29 June Introduction to nanotechnologies for medicine and healthcare Nanoparticles in medicine Dr Helen Townley Nanoparticles characterisation techniques Nanoparticle - cell interactions Dr Hanene Ali-Boucetta Challenges and opportunities for nanomedicine Commercialisation of nanotechnology for medicine and healthcare - a case study Recent developments in the safety of nanomaterials Panel discussion: Challenges and opportunities for nanomedicine Drinks reception at Rewley House Prof. Robert Carlisle Prof. Barry Park Dr Helen Townley (Nuffield Department of Obstetrics and Gynaecology, and Department of Engineering Dr Hanene Ali-Boucetta. (Nanomedicine and Drug Delivery Lab, School of Clinical & Experimental Medicine, College of Medical & Dental Sciences, University of Birmingham) Prof. Robert Carlisle (Institute of Biomedical Engineering, Department of Engineering Prof. Barry Park (Director, GBP Consulting Ltd) Page 1 of 5

2 Nanotechnologies for Regenerative Medicine and Tissue Engineering Tuesday 30 June Nanotechnologies for regenerative medicine and cell therapies Scaffolds for Tissue Engineering - from the nanoscale upwards Mechanobiology: multi-scale tissue mechanics Scaffolding and nanocomposites for tissue engineering Biomimetic nanotechnologies for regenerative medicine: taking inspiration from nature Novel nano-composites in bone and cartilage tissue engineering TEA Prof. Alicia El Haj Prof. Jan Czernuszka Prof. Mark Thompson Prof. Sonia Contera Dr E. Thomas Pashuck Dr Maryam Tamaddon :30 Electrospinning in tissue engineering Dr Nick Chatterton Nanomaterials in clinical dentistry Dr Gabriela Furdui-Carr Summary and discussion Prof. Alicia El Haj (Director, Institute for Science & Technology in Medicine, Keele University) Prof. Jan Czernuszka (Department of Materials, University of Oxford) Prof. Mark Thompson (Institute of Biomedical Engineering, Department of Engineering Prof. Sonia Contera (Co-Director, Oxford Martin Programme on Nanotechnology, and Department of Physics, University of Oxford) Dr E. Thomas Pashuck (Department of Materials, Imperial College London) Dr Maryam Tamaddon (Department of Materials, University of Oxford) Dr Nick Chatterton (Department of Life, Health & Chemical Sciences, The Open University) Dr Gabriela Furdui-Carr, DDS (NATO Dental Clinic Brussels) Page 2 of 5

3 Nanomedicine - Diagnostics Wednesday 1 July Introduction to nano-diagnostics Extracellular vesicles in health and disease Dr Rebecca Dragovic Sub-visible particles, what are they and how can we analyse them? Advanced liposome characterisation with Tunable Resistive Pulse Sensing (TRPS): from the lab to the clinic DNA sequencing using engineered nanopores Mr Ben Owen, Malvern Instruments Ltd Dr Dimitri Aubert, Izon Science Ltd Prof. Hagan Bayley DNA Microarrays Dr Douglas Hurd OGT Engineered nanoparticles for cancer diagnostics and therapy Multi-modality probes for biomedical radioimaging applications Summary and discussion Dr Helen Townley Dr Sofia Pascu Walking tour of Oxford (meet in front of Trinity College) Dr Rebecca Dragovic (Nuffield Department of Obstetrics and Gynaecology, University of Oxford) Mr Ben Owen (Malvern Instruments Ltd, Malvern, Worcestershire) Dr Dimitri Aubert (Director EMEA, Izon Science Ltd, The Oxford Science Park, Oxford) Prof. Hagan Bayley FRS (Department of Chemistry, University of Oxford) Dr Douglas Hurd (Oxford Gene Technology, Begbroke Science Park, Oxfordshire) Dr Helen Townley (Nuffield Department of Obstetrics and Gynaecology, and Department of Engineering Dr Sofia Pascu (Department of Chemistry, University of Bath) Page 3 of 5

4 Nano-Biosensors Thursday 2 July Requirements of biosensing systems Electrochemical sensing methodologies Rita Nissim Optical sensing methodologies Nano-biosensors (devices) From computer chips to biosensors: nanoscale Field Effect Transistors Challenges to prove biosensors in the clinical setting Lateral flow diagnostics: Turning a molecular principle into one of the most commonly used diagnostic tests Fluorescent biosensors and their application in cell-based assays :45 Summary and discussion Prof. Maurits de Planque Dr Ursula Gebhardt Dr Sarah Johnson Dr Alasdair Robertson Miss Rita Nissim (Department of Chemistry, University of Oxford) Prof. Maurits de Planque (School of Electronics and Computer Science, University of Southampton) Dr Ursula Gebhardt (Consultant for Business Development in Medical Technology) Dr Sarah Johnson (Swiss Precision Diagnostics, Priory Business Park, Bedford) Dr Alasdair Robertson (SAL Scientific Ltd) Page 4 of 5

5 Nano-Pharmaceuticals Friday 3 July Nanotechnologies for drug delivery and therapy: Overview Nanoparticles for drug delivery and therapeutics COFFEE Barriers and opportunities for medical nanoparticle localisation Dr Mariarosa Mazza Dr Martin Garnett Approaches to nanoparticle targeting Dr Karl Morten LUNCH Polymer-based nanoparticles for drug delivery and therapeutics Challenges in the development and commercialization of nanoparticle-based drug delivery systems TEA Dr Martin Garnett Dr Meike Roskamp Bio-nanotherapeutics Prof. Robert Carlisle Nanopharmaceuticals: current regulatory approach Summary and discussion Mr Gary Inwards, MHRA Dr Mariarosa Mazza (Nanomedicine Lab, Faculty of Medical and Human Sciences, Institute of Inflammation and Repair, University of Manchester) Dr Martin Garnett (School of Pharmacy, University of Nottingham) Dr Karl Morten (Nuffield Department of Obstetrics and Gynaecology, University of Oxford) Dr Meike Roskamp (Midatech Pharma, Begbroke Science Park, Oxfordshire) Prof. Robert Carlisle (Institute of Biomedical Engineering, Department of Engineering Mr Gary Inwards (Medicines and Healthcare products Regulatory Agency, London) Page 5 of 5