GAP Conference April 14 16, Global Academic Programs. Eliminating Cancer through Global Partnerships

Transcription

1 GAP 2015 Conference April 14 16, 2015 Eliminating Cancer through Global Partnerships Global Academic Programs

2 Global Academic Programs 2015 GAP 2015 Conference April Houston, Texas Main Building, Floor 11 Hickey Auditorium (R ) 1515 Holcombe Blvd. Houston, Texas, USA 2 Global Academic Programs

3 Dear colleagues, Welcome to Houston and The University of Texas MD Anderson Cancer Center! It s such a privilege to have you join us for the Global Academic Programs 2015 Conference. This special event brings together our spectacular partners and collaborators from around the globe, and we re honored to host all of you. Through interactive forums, focused discussions and engaging meeting sessions, we aim to create opportunities for our faculty members, trainees and others to exchange ideas and develop productive relationships. Together, we can combine our efforts to end cancer by advancing the goals of our leading research and educational programs. Thank you again for joining us for what we know will be a powerful experience. 2 Ronald A. DePinho, M.D., President The University of Texas MD Anderson Cancer Center

4 Table of Contents GAP 2015 CONFERENCE Tuesday, April :30 8:40 am Hickey Auditorium 4 Global Academic Programs Opening Ceremony Welcome Sister Institutions and Partners 8:40 11:00 am Plenary - Moon Shot Updates and Pilots - Hickey Auditorium Moon shot: Breast & Ovarian Moon shot: Leukemia (CLL) Moon shot: Lung Moon shot: Melanoma Moon shot: Prostate Moon shot: Leukemia (AML/MDS) Moon shot pilots 11:30 12:50 pm Division Highlights - Hickey Auditorium Anesthesiology & Critical Care Breast Imaging Cancer Prevention and Population Sciences Cancer Systems Imaging 1:00 2:00pm LUNCH Presentations Moving Induced Cyclin Degradation from the Bench into the Cancer Clinic Brazil GAP 2016 Presentation 1:30 4:30 pm E-Poster Session 2:30 3:50 pm Division Highlights (cont.) - Hickey Auditorium Internal Medicine Pediatrics Radiation Oncology Surgery Simultaneous Sessions/Workshops 1, 2, 3, and 4 4:20 5:50 pm Pages 4-6 Breast Cancer Hickey Auditorium Critical Role of Prospective Cohorts in Advancement of Personalized Medicine - Conference Room 4 Gastrointestinal Cancers Conference Rooms 2 and 7 Genomic Marker-guided Medicine Initiative GEMINI Project Conference Room 5 7:00 9:30 pm Welcome Address and Reception Hotel ZaZa, Phantom Ballroom

5 Table of Contents Wednesday, April :30 3:30 pm E-Poster Session 8:30 10:30 am Plenary - Transforming Cancer Care Delivery through Cutting Edge Technology Hickey Auditorium Simultaneous Sessions/Workshops 5, 6, 7, and 8 11:00 12:30 pm Pages 7-9 Genitourinary Cancers Conference Room 4 Genomic Medicine Conference Rooms 2 and 7 GAP Network Partnerships for Global Health: Promoting Global Health Through Education & Training Hickey Auditorium Immunotherapy Conference Room 5 12:30 1:30 LUNCH Presentations Global Control of Cancer Strategy for Global Health at NCI Simultaneous Sessions/Workshops 9, 10, 11, and 12 1:30-3:00 pm Pages Gynecologic Cancers Hickey Auditorium Head & Neck Cancers Conference Rooms 2 and 7 Health Services Research Conference Room 5 Operative Consortia Groups Conference Room 4 Simultaneous Sessions/Workshops 13, 14, and 15 3:30 5:00 pm Pages Hemato-oncology Hickey Auditorium Hepatobiliary Oncology: Current Controversies and Future Challenges Conference Rooms 2 and 7 Supportive and Palliative Care Conference Room 4 GAP 2015 Conference 5

6 Table of Contents Thursday, April :30 11:30 am E-Poster Session 8:30 9:30 am Plenary - DNA Damage, Checkpoint Signaling and Therapeutic Opportunities Hickey Auditorium Simultaneous Sessions/Workshops 16, 17, 18, and 19 9:30 11:00 am Pages Institute of Personalized Cancer Therapy (IPCT) Hickey Auditorium Viral Infections in Immunocompromised Cancer Patients Conference Room 4 Integrative Oncology Conference Room 5 Patient Centered Perioperative Care to Improve Oncologic Outcomes Conference Rooms 2 and 7 Simultaneous Sessions/Workshops 20, 21, 22, and 23 11:30 1:00 pm Pages Advances in Image-guided Therapy for Hepatocellular Carcinoma Conference Room 4 Oncologic Critical Care: Going Global Conference Rooms 2 and 7 Sarcoma: Moving Towards Target/Pathway Driver Therapy for Bone and Soft Tissue Sarcomas Conference Room 5 Sister Institution Network Fund (SINF) Hickey Auditorium 1:00 2:00 LUNCH Simultaneous Sessions/Workshops 24, 25, and 26 2:00 3:30 pm Pages Theranostics: Combining Imaging and Therapy for Cancer Patients Hickey Auditorium Training the Next Generation of Outstanding Clinicians: Innovations in Oncology Education Conference Rooms 2 and 7 Tumor Microenvironment Conference Room 4 NURSING PROGRAM GAP 2015 Speakers, pages GAP 2015 Sessions/Workshop List, pages GAP 2015 Poster List, pages, pages TRANSPORTATION, page 6 (For our international guests)

7 GAP 2015 Conference Eliminating Cancer through Global Partnerships Tuesday, April 14, :30 8:30 am GAP Shuttle Service from ZaZa, Wyndham, and Hilton Hotels to Hickey Auditorium and Conference Center 7:30 8:30 am Registration and Breakfast 8:30 8:40 am Welcome Remarks (Hickey Auditorium) Ronald DePinho, MD, President MOON SHOT UPDATES 8:40 9:00 am Women s cancers: triple negative breast and ovarian Gordon Mills, MD, PhD, Chair and Professor, Systems Biology Mien-Chie Hung, PhD, Chair and Professor, Molecular and Cellular Oncology Anil Sood, MD, Professor, Gynecologic Oncology and Reproductive Medicine 9:00 9:20 am Chronic lymphocytic leukemia Michael Keating, MD, Professor, Leukemia William Plunkett, PhD, Professor, Experimental Therapeutics 9:20 9:40 am Lung cancer John Heymach, MD, PhD, Chair and Professor, Thoracic/Head and Neck Medical Oncology Stephen Swisher, MD, Chair and Professor, Thoracic and Cardiovascular Surgery 9:40 10:00 am Melanoma Jeffrey Gershenwald, MD, Professor, Surgical Oncology Michael Davies, MD, PhD, Associate Professor, Melanoma Medical Oncology 10:00 10:20 am Prostate cancer Christopher Logothetis, MD, Chair and Professor, Genitourinary Medical Oncology Timothy Thompson, PhD, Professor, Genitourinary Medical Oncology Research 10:20 10:40 am Acute myeloid leukemia and myelodysplastic syndrome Guillermo Garcia-Manero, MD, Professor, Leukemia Hagop Kantarjian, MD, Chair and Professor, Leukemia 10:40 11:00 am Moon Shot Pilots Giulio Draetta, MD, PhD, Professor, Molecular and Cellular Oncology Andrew Futreal, PhD, Professor, Genomic Medicine 11:00 11:30 am Coffee Break GAP 2015 Conference 1

8 Tuesday, April 14, 2015 DIVISION HIGHLIGHTS Marshall E. Hicks, MD, Professor and Division Head, Diagnostic Imaging, MD Anderson Stephen Hahn, MD, Professor and Division Head, Radiation Oncology, MD Anderson Anesthesiology & Critical Care 11:30 11:40 am Enhanced Recovery after Cancer Surgery Thomas Aloia, MD, Associate Professor, Surgical Oncology Vijaya Gottumukkala, MD, Professor, Anesthesiology & PeriOperative Medicine Breast Imaging 11:40 11:50 am Molecular Breast Imaging Beatriz E. Adrada, MD, Associate Professor, Diagnostic Radiology 11:50 12:00 pm Optoacoustic Imaging Basak E. Dogan, MD, Associate Professor, Diagnostic Radiology Mohammed Eghtedari, MD, PhD, Assistant Professor, Diagnostic Radiology 12:00 12:10 pm Advanced Imaging of Intrathoracic Malignancies: A Multidisciplinary Approach Brett Carter, MD, Associate Professor, Diagnostic Radiology Cancer Prevention and Population Sciences 12:10 12:20 pm The Changing Burden of Hepatitis C Virus infection in the United States: Model Based Predictions Jagpreet Chhatwal, PhD, Assistant Professor, Health Services Research 12:20 12:30 pm A Unified Test of Linkage Analysis and Rare-Variant Association for Analysis of Pedigree Sequence Data Chad Huff, PhD, Assistant Professor, Epidemiology 12:30 12:40 pm Prequit fmri responses to Pleasant Cues and Cigarette-Related Cues Predict Smoking Cessation Outcomes Paul Cinciripini, PhD, Professor, Behavioral Sciences Francesco Versace, PhD, Assistant Professor, Behavioral Science 2 Global Academic Programs Cancer Systems Imaging 12:40 12:50 pm Chemical Reaction-Induced Multi-molecular Polarization (CRIMP) Pratip Bhattacharya, PhD, Associate Professor, Cancer Systems Imaging 1:00 2:00 pm Lunch and Presentation (Hickey Auditorium) 1:00 1:30 pm Moving Induced Cyclin Degradation from the Bench into the Cancer Clinic Ethan Dmitrovsky, MD, Provost and EVP American Cancer Society Professor Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, MD Anderson 1:30 2:00 pm Albert Einstein Hospital, AC Camargo Cancer Center, Barretos Cancer Hospital (Brazilian Sister Institutions) GAP 2016 Presentation

9 Tuesday, April 14, :30 4:30 pm E-Poster Sessions Internal Medicine 2:00 2:10 pm Onco-Cardiology: A New Frontier / the Role of Topoisomerase in the Development of Anthracycline- Induced Cardiotoxicity Edward Yeh, MD, Professor and Chair, Cardiology 2:10 2:20 pm Prevention of Pneumonia in Oncology Patients by Targeting Toll-like Receptors Scott Evans, MD, Associate Professor, Pulmonary Medicine 2:20 2:30 pm Advances in the Management of Metastatic Thyroid Cancer A Paradigm Shift Steven I. Sherman, MD, Professor and Chair, Endocrine Neoplasia and HD Pediatrics 2:30 2:40 pm Adoptive Immunotherapy with Ex Vivo Expanded NK Cells for Leukemia, Solid Tumors, and Brain Tumors Dean A. Lee, MD, PhD, Associate Professor, Pediatrics Patient Care 2:40 2:50 pm Developing New Therapeutic Agents for Pediatric Cancer Cindy L. Schwartz, MD, MPH, Division Head Ad Interim and Professor, Pediatrics Patient Care 2:50 3:00 pm Delivery of Chemotherapy into the Fourth Ventricle of the Brain: A Novel Therapeutic Approach for Malignant Pediatric Brain Tumors David Sandberg, MD, Clinical Specialist, Neurosurgery Radiation Oncology 3:00 3:10 pm Proton Therapy Steven J, Frank, MD, Associate Professor, Radiation Oncology 3:10 3:20 pm MRI Directed Radiation Therapy Clifton Fuller, MD, Assistant Professor, Radiation Oncology 3:20 3:30 pm Stereotactic Radiation (SBRT) Joe Y. Chang, MD, PhD, Professor, Radiation Oncology Surgery 3:30 3:40 pm Minimally Invasive and New Technology on Oncologic Surgery (MINTOS) Surena Matin, MD, Professor, Urology George Chang, MD, Associate Professor, Surgical Oncology 3:40 3:50 pm Sinonasal and Skull Base Surgery: Progress, Challenges, and Future Directions Ehab Hanna, MD, Professor, Head and Neck Surgery 3:50 4:20 pm Coffee Break Sessions (90 minutes) GAP 2015 Conference 3

10 Tuesday, April 14, :20 5:50 pm Session/Workshop 1 - Breast Cancer Hickey Auditorium Debasish Tripathy, MD, Professor and Chair, Breast Medical Oncology, MD Anderson Henry Gomez Moreno, MD, Medical Oncology, National Cancer Center of Peru -INEN (Lima, Peru) Fernando Herazo-Maya, MD, Professor, Breast Surgical Coordinator, IDC Las Americas (Medellin, Colombia) 4:20 4:30 pm Prediction of recurrence risk in breast cancer patients using an autophagy-related protein expressionbased model Lei Wang, MD, Doctoral Student, Fudan University Shanghai Cancer Center (Shanghai, China) 4:30 4:40 pm Effect of screening mammography on breast-cancer survival in Brazilian women Jose Humberto Fregnani, MD, PhD, Scientific Director, Teaching and Research Institute, Barretos Cancer Hospital (Barretos, Brazil) 4:40 4:50 pm Screening for genomic rearrangements in BRCA1 and BRCA2 genes in 16 Peruvian breast cancer families by Multiplex Ligation-dependent Probe Amplification (MLPA) Joseph Pinto, PhD, Molecular Biology, Oncosalud-Auna (Lima, Peru) 4:50 5:00 pm Acyl-CoA synthetase 4 a novel target for hormonal resistance breast cancer. Ernesto Podesta, MD, Medical Oncology, Centro de Educación Médica e Investigaciones Clinicas Norberto Quirno (CEMIC) (Buenos Aires, Argentina) 5:00 5:10 pm Targeting of mirna networks for prevention of basal like breast cancers Anjana Bhardwaj, PhD, Assistant Professor, Surgical Oncology, MD Anderson 5:10 5:20 pm Overexpression of histone demethylase KDM4A leads an epigenetic silencing of tumor suppressor gene CHD5 in a breast cancer model. Ernesto Soto-Reyes, MD, Associate Professor, Instituto Nacional de Cancerologia-InCAN (Mexico City, Mexico) 5:20 5:30 pm Status of BRCA1 / 2 and the expression of low molecular weight isoform of cyclin E in breast cancer triple negative depending on the race and survival Sira Macalou, MD, Post-Doc/Fellow, Breast Medical Oncology, MD Anderson 5:30 5:40 pm Navigation Programs s Impact in a Colombian Breast Cancer Patients Cohort Fernando Herazo-Maya, MD, Professor, Instituto de Cancerologia, Clinica Las Americas IDC (Medellin, Colombia) 5:40 5:50 pm BRCA1-loss-of-function mutations shaping the genomic and epigenomic landscape of Triple-negative breast cancer Dirce M. Carraro, PhD, Head, Laboratory of Genomics and Molecular Biology, AC Camargo Cancer Center (Sao Paulo, Brazil) 4:20 5:50 pm Session/Workshop 2 - The Critical Role of Prospective Cohorts in Advancement of Personalized Medicine Conference Room 4 Xifeng Wu, MD, PhD, Professor and Chair, Epidemiology, MD Anderson Luis Alonso Herrera, PhD, Director of Research, Instituto Nacional de Cancerologia-InCAN (Mexico City, Mexico) Mario I. Fernandez, MD, Professor, Urology, Clinica Alemana (Santiago, Chile) 4 Global Academic Programs

11 Tuesday, April 14, :20 4:35 pm Introduction and Overview Xifeng Wu, MD, PhD, Professor & Chair, Epidemiology, MD Anderson 4:35 4:50 pm The prevalence of BRCA1 and BRCA2 mutations among Mexican women with breast cancer Luis Alonso Herrera, PhD, Director of Research, Instituto Nacional de Cancerologia-InCAN (Mexico City, Mexico) 4:50 5:05 pm Association of genetic variants with the presence of bladder cancer in an arsenic-exposed population Mario A. Fernandez, MD, Professor, Urology, Clinica Alemana (Santiago, Chile) 5:05 5:20 pm Are patients clinical data important for skin cancer population screening via teledermatology? Andre Lopes Carvalho, MD, PhD, Executive Director, Teaching and Research Institute, Barretos Cancer Hospital (Barretos, Brazil) 5:20 5:35 pm Joint biobanks for easier access of common and uncommon cancer samples and data Menghong Sun, MD, Professor, Fudan University Shanghai Cancer Center (Shanghai, China) 5:35 5:50 pm The Mexican American Mano A Mano Cohort Hua Zhao, PhD, Associate Professor, Epidemiology, MD Anderson 4:20 5:50 pm Session/Workshop 3 - Gastrointestinal Cancers Conference Rooms 2 and 7 Robert Wolff, MD, Professor and Chair, Gastrointestinal Medical Oncology, MD Anderson Hyun Cheol Chung, MD, PhD, Professor, Medical Oncology, Yonsei Cancer Center (Seoul, South Korea) Ingemar Ernberg, MD, PhD, Professor and Chair, KI Cancer Network, Karolinska Institutet (Stockholm, Sweden) 4:20 4:30 pm Comparison between an Immunochemical Faecal Occult Blood Test and a Guaiac Based Faecal Occult Blood Test in detection of adenomas and colorectal cancer Samuel Aguiar Junior, MD, PhD, Professor, Surgical Oncology, AC Camargo Cancer Hospital (Sao Paulo, Brazil) 4:30 4:40 pm Establishment of Patient-Derived Xenograft as a Para-Clinical Model System in Gastric Cancer: Initial Experience from a Single Institute Yoon Young Choi, MD, Post-Doc Fellow Yonsei University Medical Center (Seoul, Korea) 4:40 4:50 pm Performance of a Nomogram Individually Predicting Overall Survival after Curative Resection with D2 Lymphadenectomy for Advanced Gastric Cancer Patients in China Wei Wang, MD, Assistant Professor, Sun Yat-sen University Cancer Center (Guangzhou, China) 4:50 5:00 pm Comparison of KRAS and PIK3CA gene status between primary tumours and paired metastases in metastatic or recurrent Colorectal Cancer Jieer Ying, MD, Professor, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 5:00 5:10 pm Analysis of pyknons expression in a Brazilian cohort of colorectal cancer patients Rui Manuel Reis, MD, PhD, Research Coordinator, Molecular Oncology Center, Barretos Cancer Hospital (Barretos, Brazil) 5:10 5:20 pm PD-L1 Expression on Gastric cancer and Its Relationship with Clinicopathologic factors Miaozhen Qiu, MD, Attending Physician, Sun Yat-sen University Cancer Center (Guangzhou, China) 5:20 5:30 pm Activation of Nuclear PTEN by Inhibition of Notch Signaling Induces G2/M Cell Cycle Arrest in Gastric Cancer Kyung-Hee Chun, MD, Assistant Professor, Yonsei University Cancer Center (Seoul, South Korea) GAP 2015 Conference 5

12 Tuesday, April 14, :30 5:40 pm Clinical relevance of circulating tumor DNA in plasma from pancreatic cancer patients Oddmund Nordgard, MD, Associate Professor, Stavanger University Hospital (Stavanger, Norway) 5:40 5:50 pm Clinical Significance of Interleukin-6 in Diagnosis of, Oral, Esophageal, Gall Bladder and Lung carcinomas Anjali Vinocha, MD, Assistant Professor, Delhi State Cancer Institute (New Delhi, India) 4:20 5:50 pm Session/Workshop 4 - Genomic Marker-guided Medicine Initiative GEMINI Project Conference Room 5 John Heymach, MD, PhD, Professor & Chair, Thoracic Head & Neck/Medical Oncology, MD Anderson Amir Onn, MD, Professor and Head, Pulmonary Institute, The Chaim Sheba Medical Center (Tel Hashomer, Israel) 4:20 4:45 pm Bites from the KRAS Slice of the Pie: Co-occuring Genomic Alterations Define Subsets of KRAS-mutant Cancer with Distinct Biology and Therapeutic Vulnerabilities John Heymach, MD, PhD, Professor & Chair, Thoracic Head & Neck/Medical Oncology, MD Anderson 4:45 5:10 pm Prospective Study of Molecular Markers in Patients With Advanced Lung Adenocarcinoma: Updated Results from GAP 2014 Recondo Gonzalo, MD, Medical Oncology, Centro de Educación Médica e Investigaciones Clinicas Norberto Quirno (CEMIC) (Buenos Aires, Argentina) 5:10 5:35 pm Novel Drivers of EMT, Metastasis, and Immunosuppression in Lung Cancer Don L. Gibbons, MD, PhD, Assistant Professor, Thoracic Head & Neck/Medical Oncology, MD Anderson 5:35 5:50 pm Repurposing Ibrutinib for Treatment of EGFR Mutant Cancer Bingliang Fang, MD, PhD, Professor, Thoracic & Cardiovascular Surgery, MD Anderson 4:30 5:30 pm GAP Shuttle Service from Hickey Auditorium and Conference Center to ZaZa, Wyndham, and Hilton Hotels Transportation (for our international guests) Tuesday, April 14 6:30-8:30 am GAP Shuttle Service from ZaZa, Wyndham and Hilton Hotels to Hickey Auditorium and Conference Center 5:00-7:00 pm GAP Shuttle Service from Hickey Auditorium and Conference Center to ZaZa, Wyndham and Hilton Hotels 6:30-7:30 pm GAP Shuttle Service from Wyndham and Hilton Hotels to Hotel ZaZa 7:00 9:30 pm Welcome Address and Reception, Ronald DePinho, MD, President, The University of Texas MD Anderson Cancer Center, Hotel ZaZa Phantom Ballroom, 5701 Main Street, Houston, TX 77005, telephone :00-10:00 pm GAP Shuttle Service from Hotel ZaZa to Wyndham and Hilton Hotels Wednesday, April 15 6:30-8:30 am GAP Shuttle Service from ZaZa, Wyndham and Hilton Hotels to Hickey Auditorium and Conference Center 4:30 5:30 pm GAP Shuttle Service from Hickey Auditorium and Conference Center to ZaZa, Wyndham and Hilton Hotels Thursday, April 16 6:30-8:30 am GAP Shuttle Service from ZaZa, Wyndham and Hilton Hotels to Hickey Auditorium and Conference Center 3:00-4:00 pm GAP Shuttle Service from Hickey Auditorium and Conference Center to ZaZa, Wyndham and Hilton Hotels 6 Global Academic Programs

13 Wednesday, April 15, :30 8:30 am GAP Shuttle Service from ZaZa, Wyndham, and Hilton Hotels to Hickey Auditorium and Conference Center 7:30 8:30 am Registration and Breakfast 7:30 3:30 pm E-Poster Sessions 8:30 10:30 am Plenary Session (Hickey Auditorium) 8:30 8:50 am Transforming Cancer Care Delivery Through Cutting Edge Technology Lynda Chin, MD, Professor and Chair, Genomic Medicine, MD Anderson 8:50 9:10 am Using Cognitive Systems in Treatment Decision Support Rob High Jr., CTO, IBM Watson Group 9:10 9:30 am Oncology Expert Advisor (OEA) Demo John V. Heymach, MD, PhD, Professor and Chair, Thoracic/Head & Neck Medical Oncology, MD Anderson 9:30 9:50 am Mobility in Healthcare Delivery Christopher Penrose, SVP, Internet of Things Solutions, AT&T 9:50 10:10 am Information Interchange to Enable a Next Generation Health System Mark Mynhier, Partner, PwC 10:10 10:30 am Summary and Q & A Lynda Chin, MD and Panel 10:30 11:00 am Coffee Break 11:00 12:30 pm Session/Workshop 5 - Genitourinary Cancers Conference Room 4 Christopher Logothetis, MD, Professor and Chair, Genitourinary Medical Oncology, MD Anderson Nicolas G. Zouain, MD, Assistant Professor, Radiation Oncology, American University of Beirut Medical Center (Beirut, Lebanon) 11:00 11:15 am Study of circulating exosomal micrornas as new biomarkers for diagnosis of renal cancer An Zhao, MD, Post-Doc/Fellow, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 11:15 11:30 am Development of a Preliminary Nomogram to Predict Progression of Bone Scan for Castration Resistant Prostate Cancer Guo-Wen Lin, MD, Post-Doc/Fellow, Fudan University Shanghai Cancer Center (Shanghai, China) 11:30 11:45 am Development and validation of nomogram to estimate the risk of prostate cancer in a Brazilian population Andre Lopes Carvalho, MD, PhD, Executive Director, Teaching and Research Institute, Barretos Cancer Hospital (Barretos, Brazil) 11:45 12:00 pm Decreased incidence rate of acute toxicity with prostate-based image-guided approach compared with boney structure-based approach in external-beam radiotherapy of prostate cancer Kiyonao Nakamura, MD, Doctoral Student, Kyoto University (Kyoto, Japan) GAP 2015 Conference 7

14 Wednesday, April 15, :00 12:15 pm Clinical and Prognostic Features of Chromophobe Renal Cell Carcinoma Zaida Morante, MD, Medical Oncology, National Cancer Center of Peru-INEN (Lima, Peru) 12:15 12:30 pm Q & A 11:00 12:30 pm Session/Workshop 6 Genomic Medicine Conference Rooms 2 and 7 Andrew Futreal, PhD, Professor, Genomic Medicine, MD Anderson Maciej Wiznerowicz, MD, PhD, Associate Professor, Greater Poland Cancer Center 11:10 11:15 am Association between VEGFA Polymorphisms and Severe Acute Oral Mucositis in Nasopharyngeal Carcinoma Patients Huai Liu, MD, PhD, Attending Physician, Hunan Provincial Cancer Hospital (Changsa, China) 11:15 11:30 am Applying TCGA data for cancer diagnostics and pathway analysis Maciej Wiznerowicz, MD, PhD, Associate Professor, Associate Professor, Polish Oncology Consortium (Warsaw, Poland) 11:30 11:45 am Prospective Study Of Molecular Markers In Patients With Advanced Lung Adenocarcinoma: Updated results from GAP 2014 Gonzalo Recondo, MD, Medical Oncology,Centro de Educación Médica e Investigaciones Clinicas Norberto Quirno (CEMIC) (Buenos Aires, Argentina) 11:45 12:00 pm CARMA: Spectral Decomposition of Copy Number Profiles in Cancer Anne-Lise Borresen-Dale, MD, Professor, Norwegian Cancer Consortium (Oslo, Norway) 12:00 12:15 pm Convergent de-differentiation during intra-patient evolution in therapy naïve melanoma Mark J. Shackleton, MD, Assistant Professor, Peter Mac Cancer Centre (Melbourne, Australia) 12:15 12:30 pm Integrated analysis of single nucleotide variants and copy number variants detected by whole exome sequencing in ovarian clear cell adenocarcinoma Murakami Ryusuke, MD, Doctoral Student, Kyoto University (Kyoto, Japan) 11:00 12:30 pm Session/Workshop 7 GAP Network Partnerships for Global Health: Promoting Global Health Through Education & Training Hickey Auditorium Ernest Hawk, MD, Division Head, Cancer Prevention & Population Sciences Edward Trimble, MD, MPH, Director, Center for Global Health, National Cancer Institute (NCI) 11:00 11:10 am National Control Plan in Peru - Hope Plan (Plan Esperanza) Tatiana Vidaurre-Rojas, MD, Director, National Cancer Center of Peru-INEN (Lima, Peru) 11:10 11:20 am Population-based screening with carehpv in El Salvador Mauricio Maza, MD, Chief Medical Officer, Basic Health International (San Salvador, El Salvador) 11:20 11:30 am MD Anderson s Tobacco Treatment Program: A Multi-Layered Tobacco Cessation Program for Cancer Patients Paul Cinciripini, PhD, Chair Ad Interim, Behavioral Science, MD Anderson 8 Global Academic Programs

15 Wednesday, April 15, :30 11:40 am Project COMET: Colombia and Mexico against Tobacco Irene Tami-Maury, DMD, MSc, DrPH, Assistant Professor, Behavioral Science, MD Anderson 11:40 11:50 am Mobilizing a Co-ordinated Response for Cancer Prevention and Control in South Africa Vikash Sewram, PhD, Director, African Cancer Institute, Stellenbosch University (Capetown, South Africa) 11:50 12:00 pm Project ECHO for cervical cancer screening and prevention in the Rio Grande Valley along the Texas- Mexico border Kathleen Schmeler, MD, Associate Professor, Gynecologic Oncology, MD Anderson 12:00 12:10 pm Pink Ribbon Red Ribbon: Advancing Women s Cancer Care in Sub-Saharan Africa Doyin Oluwole, MD, Executive Director, Pink Ribbon Red Ribbon, George W Bush Presidential Center (Dallas, Texas, USA) 11:00 12:30 pm Session/Workshop 8 Immunotherapy Conference Room 5 Cassian Yee, MD, Professor, Melanoma Medical Oncology, MD Anderson Rienk Offringa, MD, Immunotherapy, German Cancer Center DKFZ (Heidelberg, Germany) Kalle Malmberg, MD, PhD, Professor, Immunotherapy, Oslo University Hospital (Olso, Norway) 11:00 11:15 am Harnessing Adaptive NK cells in Cancer Therapy Kalle Malmberg, MD, PhD, Professor, Immunotherapy, Oslo University Hospital (Oslo, Norway) 11:15 11:30 am Mutant IDH1 as a Target for Cancer Immunotherapy Michael Platten, MD, Professor, Neurology, German Cancer Research Center-DKFZ (Heidelberg, Germany) 11:30 11:45 am Personalized Endogenous T Cell (ETC) Therapy Cassian Yee, MD, Professor, Melanoma Medical Oncology, MD Anderson 11:45 12:00 pm Implementation of T-cell Therapy in Pancreatic Ductal Adenocarcinoma Rienk Offringa, MD, Professor, Immunotherapy, German Cancer Research Center-DKFZ (Heidelberg, Germany) 12:00 12:15 pm A randomized controlled trial of autologous cytokine-induced killer cells (CIK) as an adjuvant therapy for patients with hepatocellular carcinoma (HCC) after curative resection Li Xu, MD, Associate Professor, Sun Yat-sen University Cancer Center (Guangzhou, China) 12:15 12:30 pm Combination of therapeutic vaccination with surgery in patients with resected melanoma (MM) Andrzej Mackiewicz, MD, Professor, Polish Oncology Consortium (Warsaw, Poland) 12:30 1:30 pm Lunch and Presentation (Hickey Auditorium) 12:30 1:00 pm Global Control of Cancer Tezer Kutluk, MD, PhD, FAAP, UICC President & Professor, Department of Pediatrics, Division of Pediatric Oncology, Hacettepe University Faculty of Medicine & Cancer Institute (Ankara, Turkey) 1:00 1:30 pm Strategy for Global Health at the National Cancer Institute (NCI) Edward L. Trimble, MD, Director, Center for Global Health, National Cancer Institute (NCI) GAP 2015 Conference 9

16 Wednesday, April 15, :30 3:00 pm Session/Workshop 9 Gynecologic Cancers Hickey Auditorium Larissa Meyer, MD, Assistant Professor, Gynecologic Oncology & Reproductive Medicine, MD Anderson Jose Humberto Fregnani, MD, PhD, Research Director, Barretos Cancer Hospital (Barretos, Brazil) Rene Pareja, MD, Gynecology, Instituto de Cancerologia, Clinica Las Americas IDC (Medellin, Colombia) 1:30 1:37 pm Assessing and monitoring cervical tumor in response to neoadjuvant chemotherapy using quantitative analysis of contrast-enhanced ultrasonography Xiao-Qing Pei, MD, Associate Professor, Sun Yat-sen University Cancer Center (Guangzhou, China) 1:37 1:44 pm Salvage laparoscopic lymphadenectomy combined to chemotherapy and/or radiation therapy for isolated para-aortic nodal recurrence of cervical cancer: morbidity and outcomes of a case series Audrey T. Tsunoda, MD, PhD Professor, Gynecology, Barretos Cancer Hospital (Barretos, Brazil) 1:44 2:01 pm Immediate radical trachelectomy versus neoadjuvant chemotherapy followed by radical trachelectomy for patients with stage IB1 cervical cancer with tumors 2 cm or larger: a literature review and analysis of oncological and obstetrical outcomes Rene Pareja, MD, Associate Professor, Instituto de Cancerologia, Clinica Las Americas IDC (Medellin, Colombia) Discussion 2:11 2:18 pm Single Visit Approach to Cervical Cancer Prevention SAFE Project with Scale-up program: Lessons from Thailand Khunying Kobchit, MD, Professor, Obstetrics and Gynecology, Chulalongkorn University (Bangkok, Thailand) Discussion 2:20 2:27 pm Elevating Clinical and Research Standards: An Organizational Search for Excellence by Structured Benchmarking Henrik Lajer, MD, Chief, Gyne-Oncologist, Rigshospitalet, Copenhagen University Hospital (Copenhagen, Denmark) 2:27 2:34 pm Use of laparoscopic score to determine complete cytorreduction of advanced ovarian cancer: Prospective study Carlos E. Andrade, MD, Gynecology, Barretos Cancer Hospital (Barretos, Brazil) 2:34 2:41 pm A comparative analysis in management of ovarian cancer between a major tertiary cancer center and no oncological institutions in Medellín, Colombia Gabriel J. Rendon, MD, Assistant Professor, Instituto de Cancerologia, Clinica Las Americas IDC (Medellin, Colombia) Discussion 3:08 3:15 pm Investigation on the quality of life and influential factors in Chinese women with recurrent ovarian cancer Zhu Yan Shao, MD, Post-Doc/Fellow, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 3:15 3:22 pm Clinical researching a new treatment for special histological types of the advanced-stage cervical cancer Jie Tang, MD, Professor, Hunan Cancer Hospital (Changsha, China) 10 Global Academic Programs

17 Wednesday, April 15, :30 3:00 pm Session/Workshop 10 Head & Neck Cancers Conference Rooms 2 and 7 Ehab Y. Hanna, MD, Professor, Head & Neck Surgery, MD Anderson Andre Lopes Carvalho, MD, PhD, Head & Neck Surgery, Executive Director, Teaching and Research Institute, Barretos Cancer Hospital (Barretos Brazil) Chandrashekhar Dravid, MD, Assistant Professor, Head & Neck Surgery, Delhi State Cancer Institute (New Delhi, India) 1:30 1:40 pm Establishment and Validation of Plasma Epstein-Barr Virus DNA-Based prognostic Nomograms to Predict Recurrence of Primary Non-disseminated Nasopharyngeal Carcinoma in the Endemic Area Lin-Quan Tang, MD, Doctoral Student, Sun Yat-sen University Cancer Center (Guangzhou, China) 1:40 1:50 pm Opportunistic screening for oral cancer using mobile and fixed units in Brazil Andre Lopes Carvalho, MD, PhD, Head & Neck Surgery and Executive Director, Teaching and Research Institute, Barretos Cancer Hospital (Barretos, Brazil) 1:50 2:00 pm The prediction of radiosensitivity of nasopharyngeal carcinoma based on the narrow band imaging endoscopy Xiao-guang Ni, MD, Associate Professor, Chinese Academy of Medical Sciences (Beijing, China) 2:00 2:10 pm In situ hybridization analysis of mir-146b-5p and mir-21 expression in thyroid carcinoma and Prognostic implications Zhenying Guo, MD, Attending Physician, Zheijiang Cancer Hospital (Hangzhou, China) 2:10 2:20 pm Prospective Study of Combining the Plasma Load of Epstein-Barr Viral DNA and the Tumor Response to Neoadjuvant Chemotherapy for Predicting Clinical Outcome in Advanced-Stage Nasopharyngeal Carcinoma Hai-Qiang Mai, MD, Professor, Sun Yat-sen University Cancer Center (Guangzhou, China) 2:30 2:40 pm Transcriptome Markers of Lymph Node Metastasis in Oral Squamous Cell Carcinoma Emmanuel Dias-Neto, PhD, Associate Professor, AC Camargo Cancer Center (Sao Paulo, Brazil) 2:40 3:00 pm Q & A 1:30 3:00 pm Session/Workshop 11 Health Services Research Conference Room 5 Sharon Giordano, MD, MPH, Professor & Chair, Health Services Research, MD Anderson Chun-Ru Chien, MD, PhD, China Medical University Hospital (Taichung,Taiwan) Niwat Boonyuan, MD, General, Director, Wattanosoth Cancer Hospital, Bangkok Hospital (Bangkok, Thailand) 1:30 1:45 pm Challenges in Implementing Lung Cancer Screening Programs in Primary Care Settings Robert J. Volk, PhD, Professor, Health Services Research, MD Anderson 1:45 2:00 pm Cost-effectiveness Analysis of Low-dose CT Screening for Lung Cancer in China Fei Liang, MD, Post-Doc/Fellow, Fudan University Shanghai Cancer Center (Shanghai, China) 2:00 2:15 pm Analysis of the expenses in breast cancer and lung cancer medical insurance patients in Tianjin city in Jun Li, Researcher, Tianjin Medical University Cancer Institute & Hospital (Tianjin, China) GAP 2015 Conference 11

18 Wednesday, April 15, :15 2:30 pm Cancer incidence and survival among Adolescent & Young Adults in Taiwan Chun-Ru Chien, MD, PhD, Associate Professor, China Medical University Hospital (Taichung, Taiwan) 2:30 2:45 pm A program evaluation of best practice methods to assess integrated health needs for breast cancer survivors Katherine Gilmore, Project Consultant, Cancer Survivorship, MD Anderson 2:45 3:00 pm A home-based health-promotion intervention to enhance quality of life among Chinese cancer survivors: RENEW-C Marisa C. Swartz, MD, Post-Doc/Fellow, University of Texas Medical Branch (Galveston, Texas, USA) 1:30 3:00 pm Session/Workshop 12 Operative Consortia Groups Conference Room 4 Oliver Bogler, PhD, Senior VP, Academic Affairs, VP, Global Academic Programs, MD Anderson Tezer Kutluk, MD, PhD, FAAP, UICC President & Division of Pediatric Oncology, Hacettepe University Faculty of Medicine & Cancer Institute (Ankara, Turkey) 1:30 1:45 pm Development of novel treatment for triple-negative breast cancer (TNBC) and inflammatory breast cancer (IBC) through a collaboration between USA, Japan, and Egypt Naoto Ueno, MD, PhD, Professor, Breast Medical Oncology, MD Anderson 1:45 2:00 pm Hepatocellular Carcinoma International Biomarker Assessment Consortium (HIBAC) Ahmed O. Kaseb, MD, Associate Professor and Director, Hepatocellular Carcinoma Program, Editor-in-Chief, Journal of Hepatocellular Carcinoma, MD Anderson 2:00 2:15 pm Rare Pediatric Tumors Consortium Cesar Nunez, MD, Professor, Pediatrics-Patient Care, MD Anderson 2:15 2:30 pm Global Control of Pediatric Cancers: Opportunities and Challenges Tezer Kutluk, MD, PhD, FAAP, UICC President & Division of Pediatric Oncology, Hacettepe University Faculty of Medicine & Cancer Institute (Ankara, Turkey) 3:00 3:30 pm Coffee Break 3:30 5:00 pm Session/Workshop 13 Hemato-Oncology Hickey Auditorium Hagop Kantarjian, MD, Professor & Chair, Leukemia, MD Anderson Nelson Hamerschlak, MD, PhD, Hematology-Oncology, Albert Einstein Hospital (Brazil) Alejandro Majlis, MD, Hemato-Oncology, Clinica Alemana (Santiago, Chile) 3:30 3:40 pm Post-transplant cyclophosphamide for GvHD prophylaxis in matched sibling donor allogeneic hematopoietic stem cell transplant Surapol Issaragrisil, MD, FRCP, Professor, Director, Mahidol University Hospital, Siriraj Hospital (Bangkok, Thailand) 3:40 3:50 pm Adoptive therapy using chimeric antigen receptor (CAR) modified T cells or expanded NK cells for the treatment of advanced hematologic malignancies Partow Kebriaei, MD, Assistant Professor, Leukemia, MD Anderson 12 Global Academic Programs

19 Wednesday, April 15, :50 4:00 pm Efficacy and tolerability of novel selective mitochondrial complex I inhibitor Marina Konopleva, MD, PhD, Assistant Professor, Leukemia, MD Anderson 4:00 4:10 pm Pharmacogenetics of busulfan: significant association between GSTA1 genotype, busulfan pharmacokinetics and short-term toxicity Yngvar Floisand, MD, Attending Physician, Oslo University Hospital (Oslo, Norway) 4:10 4:20 pm Restrospective comparative analysis of clinical outcomes between elderly and young patients in allogeneic hematopoietic stem cell transplantation Eduardo Chapchap, MD, Hematology, Hospital Israelita Albert Einstein (Sao Paulo, Brazil) 4:20 4:30 pm Regulation of ibrutinib on microrna-21 by inhibiting NF-kB and STAT3 in multiple myeloma cells Yafei Wang, MD, Associate Professor, Tianjin Medical University Cancer Institute and Hospital (Tianjin, China) 4:30 4:40 pm Clinical significance of protein expression of EZH2 and HDAC1, 2 in T-cell lymphoma Huilai Zhang, MD, Associate Professor, Tianjin Medical University Cancer Institute & Hospital (Tianjin, China) 4:40 4:50 pm Comparison of the effect of prophylactic lamivudine plus adefovir dipivoxil versus lamivudine alone in preventing hepatitis B reactivation in HBsAg-positive lymphoma patients undergoing chemotherapy Qingqing Cai, MD, Assistant Professor, Sun Yat-sen University Cancer Center (Guangzhou, China) 3:30 5:00 pm Session/Workshop 14 Hepatobiliary Oncology: Current Controversies and Future Challenges Conference Rooms 2 and 7 Thomas Aloia, MD, Associate Professor, Surgical Oncology, MD Anderson Milind Javle, MD, Professor, GI Medical Oncology, MD Anderson Oral Abstract Presentations (8 minutes presentation/2 minutes discussion) 3:30 3:40 pm Surgical management of patients with hepatocellular carcinoma beyond BCLC recommendation and survival analysis Yefan Zhang, MD, Post-Doc/Fellow, Chinese Academy of Medical Sciences (Beijing, China) 3:40 3:50 pm Solid pseudopapillary neoplasms of the pancreas: a 19-year multicenter experience in China Pengfei Yu, MD, Assistant Professor, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 3:50 4:00 pm Yonsei Criteria in Minimally Invasive Surgery for Left Sided Pancreatic Cancer Chang Moo Kang, MD, Associate Professor, Yonsei University Medical Center (Seoul, Korea) 4:00 4:15 pm Discussion Neoadjuvant and Adjuvant Therapy for Biliary Cancer Milind Javle, MD, Professor, GI Medical Oncology, MD Anderson 4:15 4:30 pm Hepatobiliary Interactive Case Presentations with Expert Panel Thomas Aloia, MD, Associate Professor, Surgical Oncology, MD Anderson 4:30 5:00 pm Q & A GAP 2015 Conference 13

20 Wednesday, April 15, :30 5:00 pm Session/Workshop 15 - Supportive and Palliative Care Conference Room 4 David Hui, MD, Assistant Professor, Palliative Care Medicine, MD Anderson Carlos Pavia, MD, Palliative Care, Barretos Cancer Hospital (Barretos, Brazil) Omar Shamieh, MD, Chairman, Palliative Care Department, King Hussein Cancer Center (Amman, Jordan) 3:30 3:50 pm Multi-center Research in Supportive and Palliative Oncology: Challenges and Opportunities David Hui, MD, Assistant Professor, Palliative Care Medicine, MD Anderson 3:50 4:00 pm Use of palliative chemo- and radiotherapy at the end of life in oncology patients: prospective cohort study Zhe Zhang, MD, Post-Doc/Fellow, Fudan University Shanghai Cancer Center (Shanghai, China) 4:00 4:10 pm Place of death for patients treated at a tertiary cancer center in the Middle East Omar Shamieh, MD, MBA, Chairman, Palliative Care Department, King Hussein Cancer Center (Amman, Jordan) 4:10 4:20 pm Practicability and clinical impact of the web-based Edmonton Symptom Assessment Scale (ESAS) application: Pilot study for the Internet-based Computerized Patient Assessment System (icompass) Project Michael A. Mejia, MD, Training Officer, Benavides Cancer Institute, University of Santo Tomas Hospital (Manila, Philippines) 4:20 4:30 pm Sleep Disturbance Contributes to CRF in Cancer Patients with Active Disease Diwakar Balachandran, MD, Associate Professor, Palliative Care Medicine, MD Anderson 4:30 4:40 pm Preoperative embolization in surgical treatment of spinal metastases: a randomized clinical trial of efficacy in decreasing intraoperative blood loss Benny Dahl, MD, Professor, Rigshospitalet, Copenhagen University Hospital (Copenhagen, Denmark) 4:40 4:50 pm End-of-life care stress, Spiritual well-being and Burnout among Critical care nurses Kim Hyun Sook, RN, Yonsei University Medical Center (Seoul, Korea) Discussion 4:30 5:30 pm GAP Shuttle Service from Hickey Auditorium and Conference Center to ZaZa, Wyndham, and Hilton Hotels 14 Global Academic Programs

21 Thursday, April 16, :30 8:30 am GAP Shuttle Service from ZaZa, Wyndham, and Hilton Hotels to Hickey Auditorium and Conference Center 7:30 8:30 am Registration and Breakfast 7:30 11:30 am E-Poster Sessions 8:30 9:30 am Plenary Session (Hickey Auditorium) DNA Damage, Checkpoint Signaling and Therapeutic Opportunities Helen Piwnica-Worms, PhD, Vice Provost, Science 9:30 11:00 am Session/Workshop 16 Institute of Personalized Cancer Therapy (IPCT) Hickey Auditorium John Mendelsohn, MD, Director, Khalifa Institute for Personalized Cancer Therapy and Past President, MD Anderson Gunnar Saeter, MD, PhD, Head, Institute for Cancer Research, Olso University Hospital (Oslo, Norway) Vladimir Lazar, MD, PhD, Founder and Chief Operating Officer of WIN Consortium, Head, Integrated Biology Platform, Institute Gustave Roussy (Villejuif, France) 9:30 9:45 am Predictive value of early and late [18F]FDG-PET/CT uptake in elderly patients with stagei-ii non-small-cell lung cancer treated with stereotactic body radiotherapy (SBRT) Ningbo Liu, MD, Associate Professor, Tianjin Medical University Cancer Institute & Hospital (Tianjin, China) 9:45 10:00 am Enhanced expression of cohesin loading factor NIPBL confers poor prognosis and chemotherapy resistance in non-small cell lung cancer Weizhen Xu, MD, Associate Professor, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 10:00 10:15 am Proline-rich tyrosine kinase 2 and its phosphorylated form py881 are novel prognostic markers for nonsmall cell lung cancer progression and patients overall survival Bo-hua Kuang, MD, Doctoral Student, Sun Yat-sen University Cancer Center (Guangzhou, China) 10:15 10:30 am MetAction n-of-1 trial: Actionable target identification for palliative systemic therapy - paving the way for personalized cancer therapy in Norway Anne-Lise Borresen-Dale, MD, Professor, Norwegian Cancer Consortium (Oslo, Norway) 10:30 10:45 am Two-staged approach in identifying therapeutic targets for patients with advanced cancers Russell R. Broaddus, MD, PhD, Professor, Pathology, MD Anderson 10:45 11:00 am Overview of Personalized Cancer Therapy at MD Anderson Gordon Mills, MD, PhD, Professor and Chair, Systems Biology, MD Anderson 9:30 11:00 am Session/Workshop 17 Viral Infections in Immunocompromised Cancer Patients Conference Room 4 Roy F. Chemaly, MD, MPH, Professor, Director, Infectious Diseases, MD Anderson Nelson Hamerschlak, MD, PhD, Chief, Hematology-oncology, Albert Einstein Hospital (Sao Paulo, Brazil) Surapol Issaragrisil, MD, FRCP, Professor, Director, Mahidol University, Siriraj Hospital, (Bangkok, Thailand) Javier Adachi, MD, Associate Professor, Infectious Diseases, MD Anderson GAP 2015 Conference 15

22 Thursday, April 16, :30 9:35 am Welcome Remarks 9:35 10:05 am Future Strategies for Prevention of CMV Infection after Hematopoietic Stem Cell Transplantation Roy F. Chemaly, MD, MPH, Professor, Infectious Diseases, MD Anderson 10:05 10:35 am The Role of Serum Neutralizing Antibody in Protection against Respiratory Syncytial Virus Disease Pedro Piedra, MD, Professor, Molecular Virology and Microbiology, Pediatrics, Baylor College of Medicine 10:35 10:45 am Viral Respiratory Infections in a Brazilian Cancer Center Ivan Franca, MD, Director, Infectious Diseases, AC Camargo Cancer Hospital (Sao Paulo, Brazil) 10:45 10:55 am Immune Monitoring with the T-spot-CMV assay of ALL-HCT recipients: A proof of concept in the clinical setting Dimpy Shah, PhD, Post-Doc/Fellow, Infectious Diseases, MD Anderson 10:55 11:00 am Closing Remarks 9:30 11:00 am Session/Workshop 18 Integrative Oncology Conference Room 5 Lorenzo Cohen, PhD, Professor, General Oncology Research, MD Anderson Paulo de Tarso de Lima, MD, Albert Einstein Hospital (Sao Paulo, Brazil) Rajesh K. Grover, MD, PGDHHM, Director and CEO, Delhi State Cancer Institutes 9:30 9:40 am Overview of Integrative Oncology and the Role of Lifestyle in Oncology Lorenzo Cohen, PhD, Professor, General Oncology Research, MD Anderson 9:40 10:00 am MD Anderson Integrative Medicine Program: Following an Evidence-Based Approach Lorenzo Cohen, PhD, Professor, General Oncology Research, MD Anderson 10:00 10:30 am Integrative Oncology in Brazil the Hospital Israelita Albert Einstein (HIAE) Experience Paulo de Tarso Ricieri de Lima, MD, Integrative Medicine, Hospital Israelita Albert Einstein (Sao Paulo, Brazil) 10:30 10:40 am Integrating Integrative Medicine the Delhi State Cancer Institute (DSCI) Vision Rajesh Grover, MD, PDGHHM, Director and CEO, Delhi State Cancer Institute (New Delhi, India) 10:40 11:00am Integrative Medicine in Cancer Management A Holistic Approach Vinita Jaggi Kumar, MD, Assistant Professor, Oncosurgery, Gynecology, Delhi State Cancer Institute (New Delhi, India) 9:30 11:00 am Session Workshop 19 - Patient Centered Perioperative Care to Improve Oncologic Outcomes Conference Rooms 2 and 7 Vijaya Gottumukkala, MD, Professor, Anesthesiology & Perioperative Medicine, MD Anderson Henrik Kehlet, MD, PhD, Surgical Pathophysiology, Rigshospitalet (Copenhagen, Denmark) Bernhard Riedel, MB.ChB. FCA. MBA. PhD, Director, Department of Anaesthetics, Peter MacCallum Cancer Centre (Melbourne, Australia) 16 Global Academic Programs

23 Thursday, April 16, 2015 Welcome and Introductions 9:30 9:35 am Patient Centered Perioperative Care to Improve Oncologic Outcomes Vijaya Gottumukkala, MD, Professor, Anesthesiology, MD Anderson 9:35 9:45 am Why is Surgical Patient Still at Risk for Delayed Recovery? Henrik Kehlet, MD, PhD, Surgical Pathophysiology, Righospitalet, Copenhagen University (Copenhagen, Denmark) 9:45 9:55 am Future of Perioperative Care of the Cancer Patient: How Can We Improve Outcomes? Berhard Riedel, MD, Director, Department of Anaesthetics, Peter MacCallum Cancer Centre (Melbourne, Australia) 9:55 10:00 am Discussion: Gottumukkala/Kehlet/Riedel Team presentations from SIN on various ER efforts 10:00 10:05 am Rigshospitalet Report on ER Initiative Henrik Kehlet, MD, PhD, Surgical Pathophysiology, Righospitalet, Copenhagen University (Copenhagen, Denmark) 10:05 10:10 am Peter Mac Report on ER Initiative Berhard Riedel, MD, Director, Department of Anaesthetics, Peter MacCallum Cancer Centre (Melbourne, Australia) 10:10 10:15 am MDA report on ER in Liver Surgery Thomas Aloia, MD, Associate Professor, Surgical Oncology, MD Anderson Vijaya Gottumukkala, MD, Associate Professor, Anesthesiology, MD Anderson 10:15 10:20 am MDA Report on ER in Pulmonary & Esophageal surgery David C. Rice, MD, Professor, Thoracic & Cardiovascular Surgery, MD Anderson Gabriel E. Mena, MD, Associate Professor, Anesthesiology & Perioperative Medicine, MD Anderson 10:20 10:25 am MDA Report on ER Gynecologic Surgery Larissa A. Meyer, MD, Assistant Professor, Gynecologic Oncology and Reproductive Medicine, MD Anderson Javier Lasala, MD, Assistant Professor, Anesthesiology & Perioperative Med., MD Anderson 10:25 10:30 am MDA Report on ER in Genitourinary Surgery Jay Bakul Shah, MD, Assistant Professor, Urology, MD Anderson Juan P. Cata, MD, Assistant Professor, Anesthesiology, MD Anderson 10:30 10:45 am Discussion: Speakers as panel members 10:45 10:55 am Developing an integrated roadmap of project, team, and leadership actions for accelerating implementation of enhanced recovery after surgery programs; what works, where, and when? John D. Calhoun, MD, MS, Professor, Inst Cancer Care Innovation, MD Anderson 10:55 11:00 am Discussion: Moderator Berhard Riedel 11:00 11:30 am Coffee Break GAP 2015 Conference 17

24 Thursday, April 16, :30 1:00 pm Session/Workshop 20 Advances in Image-guided Therapy for Hepatocellular Carcinoma Conference Room 4 Rony Avritscher, MD, Associate Professor, Interventional Radiology, MD Anderson Donald Schomer, MD, Chair, Diagnostic Radiology, Banner MD Anderson (Gilbert, Arizona) Wentao Li, MD, PhD, Professor, Interventional Radiology, Fudan University Shanghai Cancer Center (Shanghai, China) 11:30 11:45 am HCC: Management Strategies in Advanced and Palliative Setting Alda L. Tam, MD, Associate Professor, Interventional Radiology, MD Anderson 11:45 12:00 pm Analysis of survival factors in patients with intermediate-advanced hepatocellular carcinoma treated with transcatheter arterial chemoembolization combined with sorafenib Guoliang Shao, MD, Professor, Zhejiang Provincial Cancer Hospital (Hangzhou, China) 12:00 12:15 pm Unresectable HCC Combination Therapies Sanjay Gupta, MD, Professor, Interventional Radiology, MD Anderson 12:15 12:30 pm In vitro three-dimensional morphometric analysis for hepatectomy of centrally located hepatocellular carcinoma: A pilot study Weiqi Rong, MD, Professor, Chinese Academy of Medical Sciences (Beijing, China) 12:30 12:45 pm Perioperative Localization of Pulmonary Ground-Glass Opacity Lesions: Role of Interventional Radiology Paula Barbosa, MD, Chief of Computed Tomography Section, AC Camargo Cancer Center (Sao Paulo, Brazil) 11:30 1:00 pm Session/Workshop 21 Oncologic Critical Care: Going Global Conference Rooms 2 and 7 Kristen J. Price, MD, Professor and Chair, Critical Care, MD Anderson Cristina Prata Amendola, MD, Head, Intensive Care Unit, Barretos Cancer Hospital (Barretos, Brazil) Chanchai Sittipunt, MD, Associate Professor, Pulmonary Critical Care Medicine, Chulalongkom University (Bangkok, Thailand) 11:30 11:35 am Welcome Kristen Price, MD, Professor and Chair, Critical Care, MD Anderson :40 am Global Oncological Critical Care Research Network Joseph Nates, MD, MBA, Professor, ICU Medical Director & Deputy Chair, Critical Care, MD Anderson 11:40 12:00 pm Can Goal Directed Therapy Prevent Acute Kidney Injury in ICU? Cristina Prata Amendola, MD, Chief of Service, Intensive Care, Barretos Cancer Hospital (Barretos, Brazil) 12:00 12:20 pm Diffuse Alveolar Hemorrhage in Patients with Stem Cell Transplant Nisha Rathi, MD, Assistant Professor, Critical Care, MD Anderson 12:20 12:40 pm Outcomes of Critically Ill Cancer Patients Silvio Namendys-Silva, MD, Head, Critical Care Medicine, Instituto Nacional de Cancerologia-InCAN (Mexico City, Mexico) 18 Global Academic Programs

25 Thursday, April 16, :40 1:00 pm Smoke Cessation in ICU/CCU Patients Chanchai Sittipunt, MD, Associate Professor, Pulmonary Critical Care Medicine, Chulalongkorn University (Bangkok, Thailand) 11:30 1:00 pm Session/Workshop 22 Sarcoma: Moving Towards Target/Pathway Driver Therapy for Bone and Soft Tissue Sarcomas Conference Room 5 Shreyaskumar Patel, MD, Professor, Sarcoma Medical Oncology, MD Anderson 11:30 11:45 am Efficacy of hypofractionated radiotherapy in preoperative setting in patients with locally advanced primary myxoid liposarcoma Iwona Lugowska, MD, PhD, Maria Sklodowska Curie Oncology Institute (Warsaw, Poland) 11:45 12:00 pm CircSarc - Disease monitoring by liquid biopsies in sarcomas Leonardo Meza-Zepeda, MD, Professor, Medical Oncology, Oslo University Hospital (Oslo, Norway) 12:00 12:15 pm NoSarC Norwegian Sarcoma Consortium - Personalized treatment for orphan cancer Leonardo Meza-Zepeda, MD, Professor, Medical Oncology, Oslo University Hospital (Oslo, Norway) 12:15 12:30 pm Whole exome and targeted sequencing of Angiosarcomas: Target identification and treatment implications Ravi Vinod, MD, Associate Professor, Sarcoma Medical Oncology, MD Anderson 12:30 1:00 pm Discussion 11:30 1:00 pm Session/Workshop 23 Sister Institution Network Fund (SINF) Hickey Auditorium Oliver Bogler, PhD, Sr. VP Academic Affairs, VP GAP, MD Anderson ChaoNan (Miles) Qian, MD, PhD, Professor and Vice President, Sun Yat-sen University Cancer Center (Guangzhou, China) 11:30 11:38 am CXCL17 suppresses migration of breast cancer cells due to EMT inhibition Ya-jie Guo, MD, Professor, Fudan University Shanghai Cancer Center (Shanghai, China) 11:38 11:46 am Proteomic response in breast cancer treated with neoadjuvant chemotherapy with and without bevacizumab: Reverse phase protein array (RPPA) results from NeoAva - a randomized phase II study Mads H. Haugen, PhD, Post-Doc/Fellow, Institute for Cancer Research, Oslo University Hospital (Oslo, Norway) 11:46 11:52 am Variation of Tumor Infiltrating Lymphocytes during Neoadjuvance in Triple-Negative Breast Cancer Carlos A. Casteneda, MD, Executive Director, Department of Investigation, National Cancer Institute of Peru-INEN (Lima, Peru) 11:52 12:00 pm VISA systems targeting to breast cancer and breast cancer stem cells Xiaoming Xie, MD, Professor and Chair, Breast Surgery, Sun Yat-sen University Cancer Center (Guangzhou, China) 12:00 12:08 pm Integration of single-cell omics with spatially resolved assays to assess intra-tumor heterogeneity in locally advanced breast cancers treated with neoadjuvant chemotherapy Nicola Crosetto, MD, Assistant Professor, Medical Biophysics and Biochemistry, Karolinska Institutet (Stockholm, Sweden) GAP 2015 Conference 19