PATCH TEST ALLERGENS

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1 PATCH TEST ALLERGENS approved as pharmaceutical drugs by the Paul-Ehrlich-Institute, Germany Order Form (valid since: June 2014) Name:... Imported and distributed by Address: Country:... Date:... Baseline Series Sets complete Baseline Series Set (Substances 1 28) in service and storage box Baseline Series refill-package (Substances 1 28) E9001 E9000 For internal use only Customer No. Order No. TROLAB Baseline Series (European) The Baseline series consists of the minimum recommended test set to be used during routine diagnostic patch test investigations and which will be ordinarily supplemented by additional series and other allergens as appropriate to adequately investigate the clinical problem. 1 Potassium Dichromate 0.5 % E Neomycin Sulphate 20 % E Thiuram Mix * 1 % E Fragrance Mix II** 14 % E Cobalt Chloride, 6H 2 O 1 % E Paraphenylenediamine free Base 1 % E Benzocaine 5 % E Formaldehyde (in water) 1 % E Colophony 20 % E Clioquinol 5 % E Balsam of Peru 25 % E N-Isopropyl-N -phenyl Paraphenylenediamine 0.1 % E Wool Alcohols 30 % E Epoxy Resin 1 % E Mercapto Mix *** 1 % E Budesonide 0.1 % E Paraben Mix **** 16 % E Paratertiarybutyl Phenol Formaldehyde Resin 1 % E Fragrance Mix ***** 8 % E Quaternium-15 1 % E Nickel Sulphate, 6H 2 O 5 % E Chloro-2-methyl-4-isothiazolin-3-one + 2-Methyl-4-isothiazolin-3-one (3:1 in water) 0.01 % E Mercaptobenzothiazole 2 % E Sesquiterpene Lactone Mix 0.1 % E Tixocortol pivalate 1 % E Dibromodicyanobutane 0.3 % E Hydroxymethylpentylcyclohexenecarboxaldehyde (chemical name for the synthetic 5 % E2824 fragrance Lyral, Kovanol ) 28 Primin ( important in only some countries ) 0.01 % E0032 * single constituents see Rubber chemicals ** single constituents see Perfumes, Flavours *** single constituents see Rubber chemicals **** single constituents see Preservatives ***** single constituents see Perfumes, Flavours BS Control irritant Sodiumlaurylsulfate (sls) (in water) 0.25 % E2893 Antioxidants 1 Butyl Hydroxytoluene 2 % E Butyl Hydroxyanisole 2 % E Dodecyl Gallate (Lauryl Gallate) 0.3 % E tert.-butylhydroquinone 1 % E Propyl Gallate 0.5 % E Octyl Gallate 0.3 % E2495 Bakery Allergens 1 Vanillin 10 % E Eugenol * 1 % E Isoeugenol * 1 % E Sodium Benzoate 5 % E Butyl Hydroxytoluene 2 % E Menthol 1 % E Cinnamyl Alcohol 1 % E Cinnamaldehyde 1 % E Butyl Hydroxyanisole 2 % E Sorbic Acid 2 % E Octyl Gallate 0.3 % E Dipentene (dl-limonene) 2 % E Propyl Gallate 0.5 % E Dodecyl Gallate (Lauryl Gallate) 0.3 % E2496 * Ingredients of the Fragrance Mix (E0029) IR AO BA Ordering: Status as of June 2014 Phone: Fax: [email protected] Mail: Smartpractice Europe GmbH - Auftragsannahme, Scholtzstrasse 6, D Reinbek (Germany) Art.-Nr. E9103 Date: 0614_80802-E

2 2 Cosmetics COS Cutting oils II (historical) continued CO II 1 Hydroquinone 1 % E Toluenesulphonamide Formaldehyde Resin 10 % E Abitol 10 % E Benzyl Salicylate 1 % E Vanillin 10 % E Lemon Grass Oil 2 % E Balsam of Tolu 20 % E Cocamidopropylbetaine (in water) 1 % E Abietic Acid 10 % E Sodium Benzoate 5 % E Benzyl Alcohol 1 % E Dexpanthenol 5 % E Sodium Metabisulfite 1 % E Benzophenone 4 10 % E2500 Cutting oils I (current) 1 7-Ethylbicyclooxazolidine 1 % E ,3,5-Tris(2-hydroxyethyl)- hexahydrotriazine 1 % E Triclosan 2 % E Benzotriazole 1 % E Benzylhemiformal 1 % E Trolamine (Triethanolamine) 2.5 % E Monoethanolamine 2 % E Abietic Acid 10 % E Diethanolamine 2 % E Octylisothiazolinone % E Methylene-bis(methyloxazolidine) 1 % E Paratertiary Butylphenol 1 % E Di-n-Butylphthalate 5 % E Di-2-Ethylhexyl-Phthalate 5 % E Tricresyl Phosphate 5 % E Polyethylene Glycol Ointment 100 % E Isopropyl Myristate 10 % E Adeps lanae 30 % E Propyleneglycol 5 % E Butyl Hydroxytoluene 2 % E Phenoxyethanol 1 % E tert.-butylhydroquinone 1 % E Cetyl/Stearyl Alcohol 20 % E Bis(diethyldithiocarbamato) Zinc 1 % E ,2-Benzisothiazolin-3-one, Na-Salt 0.1 % E Diglycolamine 1 % E Iodopropynyl Butylcarbamate 0.2 % E2883 Cutting oils II (historical) 1 Chloroxylenol 1 % E Chloracetamide 0.2 % E Dipentene (dl-limonene) 2 % E Coconut Diethanolamide 0.5 % E Nitrobutylmorpholine / Ethylnitrotrimethylenedimorpholine 1 % E Dibromodicyanobutane 0.2 % E Hexamethylenetetramine 1 % E2318 CO I CO II 8 Chlorocresol 1 % E Morpholinylmercaptobenzothiazole 0.5 % E Ethylenediamine Dihydrochloride 1 % E Bronopol 0.5 % E0107 Dental Materials 1 Menthol 1 % E Peppermint Oil 2 % E Benzoyl Peroxide 1 % E Hydroquinone 1 % E Bisphenol A 1 % E Methyl Methacrylate 2 % E N,N-Dimethyl-p-Toluidine 2 % E Ethyleneglycol Dimethacrylate 2 % E Triethyleneglycol Dimethacrylate 2 % E BIS-GMA 2 % E Diurethane Dimethacrylate 2 % E (2-Hydroxyethyl) Methacrylate (2-HEMA) 1 % E Eugenol * 1 % E Ammoniated Mercury 1 % E Potassium Dicyanoaurate (in water) % E Sodium Thiosulfatoaurate 0.25 % E Palladium Chloride 1 % E Ammonium Tetrachloroplatinate 0.25 % E Amalgam 5 % E Amalgam Alloying Metals 20 % E2508 * Ingredient of the Fragrance Mix (E0029) Disinfectants 1 Chlorhexidine Digluconate (in water) 0.5 % E Glutar(di)aldehyde 0.3 % E Benzalkonium Chloride 0.1 % E Cetylpyridinium Chloride 0.1 % E Glyoxal Trimer (Dihydrate) 1 % E Cetalkonium Chloride 0.1 % E2433 Epoxy Resin Systems Reactive diluents 1 Cresylglycidylether 0.25 % E Phenylglycidylether 0.25 % E Butylglycidylether 0.25 % E ,6-Hexanedioldiglycidylether (techn. grade) 0.25 % E ,4-Butanedioldiglycidylether 0.25 % E p-tert-butylphenylglycidylether 0.25 % E2880 Hardeners 7 Ethylenediamine Dihydrochloride 1 % E Triethylenetetramine 0.5 % E ,4 -Diaminodiphenyl Methane 0.5 % E Isophoronediamine 0.5 % E Hexamethylenetetramine 1 % E Trimethylhexane-1,6-diamine (isomere blend) 0.5 % E2946 DM DIS ERS

3 3 Hairdressing 1 4-Toluenediamine (dye complex) 1 % E Glyceryl Monothioglycolate 1 % E Monoethanolamine 2 % E Ammonium Persulphate 2.5 % E Aminophenol 1 % E Aminophenol 1 % E Cocamidopropylbetaine (in water) 1 % E Hydroquinone 1 % E Resorcinol 1 % E2865 Industrial Biocides 1 7-Ethylbicyclooxazolidine 1 % E Chloroxylenol 1 % E Chloracetamide 0.2 % E ,3,5-Tris(2-hydroxyethyl)- hexahydrotriazine 1 % E Triclosan 2 % E Benzylhemiformal 1 % E Nitrobutylmorpholine / Ethylnitrotrimethylenedimorpholine 1 % E Octylisothiazolinone % E Methylene-bis(methyloxazolidine) 1 % E Dibromodicyanobutane 0.2 % E ,2-Benzisothiazolin-3-one, Na-Salt 0.1 % E Chlorocresol 1 % E Benzotriazole 1 % E Iodopropynyl Butylcarbamate 0.2 % E Methylisothiazolinone (in water) 0.05 % E2950 Medicaments I - Antibiotics 1 Bacitracin 20 % E Chloramphenicol 5 % E Gentamycin Sulphate 20 % E Kanamycin Sulphate 10 % E Tetracycline Hydrochloride 2 % E Sulfanilamide 5 % E Erythromycin 1 % E Oxytetracycline 3 % E Framycetin Sulphate 10 % E2311 Medicaments II - Antiseptics, Antimycotics 1 Nystatin 2 % E Chlorquinaldol 5 % E Fusidic Acid Sodium Salt 2 % E Clotrimazole 5 % E Dichlorophene 0.5 % E2316 Medicaments III - Miscellaneous 1 Benzoyl Peroxide 1 % E Ethylenediamine Dihydrochloride 1 % E Bufexamac 5 % E Propolis 10 % E Resorcinol 1 % E2865 HD IB ME I ME II ME III Medicaments IV - Local Anaesthetics 1 Cinchocaine Hydrochloride 5 % E Tetracaine (Amethocaine) Hydrochloride 1 % E Lidocaine Hydrochloride 15 % E Polidocanol 3 % E Procaine Hydrochloride 2 % E2308 Medicaments V - Corticosteroids 1 Amcinonide 0.1 % E Betamethasone-17-valerate 0.12 % E Clobetasol-17-propionate 0.25 % E Hydrocortisone 1 % E Hydrocortisone-17-butyrate 0.1 % E Triamcinolone Acetonide 0.1 % E Prednisolone 1 % E2505 Medicaments VI - Ophthalmics 1 Atropine Sulfate (in water) 1 % E Edetic Acid Disodium Salt 1 % E Phenylephrine Hydrochloride (in water) 10 % E Pilocarpine Hydrochloride (in water) 1 % E Polymyxin B Sulfate 3 % E2437 Metal Compounds 1 Ammoniated Mercury 1 % E Potassium Dicyanoaurate (in water) % E Sodium Thiosulfatoaurate 0.25 % E Ammonium Tetrachloroplatinate 0.25 % E Palladium Chloride 1 % E Copper Sulphate, 5H 2 O (in water) 1 % E Tin (II)-chloride 0.5 % E2419 Methacrylates 1 (2-Hydroxyethyl) Methacrylate (2-HEMA) 1 % E Methyl Methacrylate 2 % E Ethyleneglycol Dimethacrylate 2 % E Triethyleneglycol Dimethacrylate 2 % E BIS-GMA 2 % E Diurethane Dimethacrylate 2 % E Hydroquinone 1 % E N,N-Dimethyl-p-Toluidine 2 % E Benzoyl Peroxide 1 % E0201 Perfumes, Flavours 1 Benzyl Salicylate 1 % E Benzylcinnamate 5 % E Salicylaldehyde 2 % E Vanillin 10 % E Benzyl Alcohol 1 % E Benzaldehyde 5 % E Menthol 1 % E Dipentene (dl-limonene) 2 % E Gamma Methyl Ionone 1 % E Anisyl Alcohol 1 % E alpha-amylcinnamyl Alcohol 1 % E Benzyl Benzoate 1 % E2889 ME IV ME V ME VI MC MA PF

4 4 Perfumes, Flavours continued PF Photographic Chemicals PC 13 Lilial 10 % E Linalool (stabilized) 10 % E Methyl Heptine Carbonate 1 % E Majantol 5 % E2885 Essential Oils / Extracts 17 Tree Moss 1 % E Clove Oil 2 % E Orange Oil 2 % E Cedarwood Oil 10 % E Eucalyptus Oil 2 % E Laurel Leaf Oil 2 % E Lemon Grass Oil 2 % E Lemon Oil 2 % E Neroli Oil 2 % E Peppermint Oil 2 % E Ylang-ylang (I+II)-Oil 10 % E Narcissus absolute 2 % E Jasmin absolute 5 % E Sandalwood oil 10 % E Patchouli oil 10 % E2937 Constituents of the Fragrance Mix 8% in pet (E0029) 32 Cinnamyl Alcohol 1 % E Cinnamaldehyde 1 % E Eugenol 1 % E alpha-amyl-cinnamaldehyde 1 % E Hydroxycitronellal 1 % E Geraniol 1 % E Isoeugenol 1 % E Oak Moss Absolute 1 % E Sorbitan Sesquioleate 20 % E1703 Constituents of the Fragrance Mix II 14% in pet (E2860)* 41 Citral 2 % E Citronellol 1 % E Farnesol 5 % E Coumarin 5 % E alpha-hexyl cinnamaldehyde 10 % E2836 * Hydroxymethylpentylcyclohexenecarboxaldehyde (Lyral ) (E2824) is part of the Fragranc e Mix II. Lyral is not included in this test series as Lyral is already tested in the Baseline Series. Photoallergens 1 5-Bromo-4 -chlorosalicylanilide 1 % E Hexachlorophene 1 % E Bithionol 1 % E Sulfanilamide 5 % E Promethazine Hydrochloride 0.1 % E Quinidine Sulphate 1 % E Fragrance Mix 8 % E Aminobenzoic Acid * (PABA) 10 % E Ethylhexyl-4-Dimethylaminobenzoate *10 % E Benzophenone 4 * 10 % E tert-Butyl-4 -Methoxy- Dibenzoylmethane * 10 % E Isoamyl-4-methoxycinnamate * 10 % E Ethylhexyl-4-Methoxycinnamate * 10 % E (4-Methylbenzylidene)-Camphor * 10 % E Phenyl-5-benzimidazole-Sulphonic Acid * 10 % E Oxybenzone * 10 % E2361 * Sunscreen Agents PA 1 Ammonium Persulphate 2.5 % E Methylaminophenol Sulphate (Metol) 1 % E Color Developer CD 2 1 % E Color Developer CD 3 1 % E Color Developer CD 4 1 % E Pyrogallol 1 % E Aminophenol 1 % E Hydroquinone 1 % E Triphenyl Phosphate 5 % E Trolamine (Triethanolamine) 2.5 % E Edetic Acid Disodium Salt 1 % E Diethanolamine 2 % E Sodium Metabisulfite 1 % E Glutar(di)aldehyde 0.3 % E2498 Plants 1 Dipentene (dl-limonene) 2 % E Usnic Acid 0.1 % E2052 Plastic Materials 1 Phenol Formaldehyde Resin, Novolac* 5 % E Abitol 10 % E Turpentine Oil 10 % E Paratertiary Butylphenol 1 % E Di-n-Butylphthalate 5 % E Tricresyl Phosphate 5 % E Triphenyl Phosphate 5 % E Dimethylphthalate 5 % E Di-2-Ethylhexyl-Phthalate 5 % E Bisphenol A 1 % E Abietic Acid 10 % E tert.-Butylcatechol 0.25 % E2810 * Patch testing of the patient s own resin is recommended. Preservatives 1 Chlorocresol 1 % E Chloroxylenol 1 % E Bronopol 0.5 % E Imidazolidinyl Urea 2 % E Phenylmercuric Acetate 0.01 % E Sorbic Acid 2 % E Chloracetamide 0.2 % E Thiomersal 0.1 % E Chlorquinaldol 5 % E Triclosan 2 % E Diazolidinyl Urea 2 % E Dibromodicyanobutane/ Phenoxyethanol (1:4) 1 % E DMDM Hydantoin (in water) 2 % E Phenoxyethanol 1 % E Sodium Metabisulfite 1 % E Dibromodicyanobutane 0.2 % E Iodopropynyl Butylcarbamate 0.2 % E Methylisothiazolinone (in water) 0.05 % E2950 PL PM PR

5 5 Preservatives continued PR Textile and Leather Dyes TD Constituents of the Paraben Mix 19 Methyl Parahydroxybenzoate 3 % E Ethyl Parahydroxybenzoate 3 % E Propyl Parahydroxybenzoate 3 % E Butyl Parahydroxybenzoate 3 % E0154 Rubber Chemicals 1 Hexamethylenetetramine 1 % E Diphenylthiourea 1 % E Dibutylthiourea 1 % E ,3-Diphenylguanidin 1 % E Bis(diethyldithiocarbamato) Zinc 1 % E N,N -Diphenyl Paraphenylenediamine 0.25 % E Bis(dibutyldithiocarbamato) Zinc 1 % E Cyclohexyl Thiophthalimide 0.5 % E ,4 -Dihydroxybiphenyl 0.1 % E Zinc dibenzyldithiocarbamate 1 % E tert.-Butylcatechol 0.25 % E2810 Constituents of the Thiuram Mix 12 Tetramethylthiuram Disulphide 0.25 % E Tetraethylthiuram Disulphide 0.25 % E Tetramethylthiuram Monosulphide 0.25 % E Dipentamethylenethiuram Disulphide 0.25 % E1017 Constituents of the Mercapto Mix 16 Dibenzothiazyl Disulphide 1 % E N-Cyclohexylbenzothiazyl Sulphenamide 1 % E Morpholinylmercaptobenzothiazole 0.5 % E1015 Shoe Allergens 1 Glutar(di)aldehyde 0.3 % E Disperse Orange 3 1 % E Acid Yellow 36 1 % E Monobenzone 1 % E Diphenylthiourea 1 % E ,3-Diphenylguanidine 1 % E Dibutylthiourea 1 % E Octylisothiazolinone % E2427 Sunscreen Agents 1 2-Phenyl-5-benzimidazole-Sulphonic Acid 10 % E tert-Butyl-4 -Methoxy-Dibenzoylmethane 10 % E Aminobenzoic Acid (PABA) 10 % E Ethylhexyl-4-Dimethylaminobenzoate 10 % E Ethylhexyl-4-Methoxycinnamate 10 % E (4-Methylbenzylidene)-Camphor 10 % E Oxybenzone 10 % E Isoamyl-4-methoxycinnamate 10 % E Benzophenone 4 10 % E2500 RC SH SA 1 Disperse Orange 3 1 % E Disperse Yellow 3 1 % E Disperse Red 1 1 % E Disperse Red 17 1 % E Disperse Blue 3 1 % E Disperse Red 11 1 % E Disperse Yellow 9 1 % E Naphthol AS 1 % E Aminophenol 1 % E Acid Yellow 36 1 % E Bismarck Brown R 0.5 % E Disperse blue % E Disperse blue % E2949 Vehicles, Emulsifiers 1 Trolamine (Triethanolamine) 2.5 % E Propyleneglycol 5 % E Sorbitan Sesquioleate 20 % E Cetyl/Stearyl Alcohol 20 % E Amerchol L % E Polyethylene Glycol Ointment 100 % E Wool alcohols ointment 100 % E Isopropyl Myristate 10 % E Adeps lanae 30 % E Coconut Diethanolamide 0.5 % E2424 Miscellaneous 1 Hexylresorcinol 0.25 % E Potassium Dichromate 0.25 % E Propyleneglycol (in water) 20 % E White Petrolatum 100 % E Aminoazobenzene 1 % E2435 Service Items 1 Empty service and storage box for 12 substances with 1 blank drawer insert D Empty service and storage box for 24 substances with 2 blank drawer inserts E Empty service and storage box for 36 substances with 3 blank drawer inserts D Empty service and storage box for 60 substances with 5 blank drawer inserts D Blank drawer inserts for service and storage box D Patient's test sheet E TROLAB Brochure E Tray* E Cover Plates* D9530 * Ask your local distributor VE MIC

6 Visit our website: The data are taken from literature. Place of Business: SmartPractice Europe GmbH Solkowskyweg 9, D22885 Barsbüttel (Germany)

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