Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK
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1 Schedule of ccreditation United Kingdom ccreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK University College London, operating UK NEQS for ccredited to UK NEQS ICC & ISH 40 Bowling Green Lane Room 127 London EC1R 0NE Contact: Keith Miller Tel: +44 (0) Fax: +44 (0) k.miller@ucl.ac.uk Website: Proficiency Testing provided from the locations specified below s covered by the organisation and their relevant activities details ctivity code UK NEQS ICC & ISH 40 Bowling Green Lane Room 127 London EC1R 0NE Local contact Dr Merdol Ibrahim merdol.ibrahim@ucl.ac.uk Main office Scheme management, operations and administration University College London dvanced Diagnostics 1st Floor Rockefeller Building 21 University Street London WC1E 6JJ Local contact Dr Merdol Ibrahim merdol.ibrahim@ucl.ac.uk Preparation of tissue blocks and microarrays Cutting sections B ssessment Manager: JR1 Page 1 of 7
2 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for DETIL OF CCREDITTION General Pathology Epithelial Markers: Cytokeratin Epithelial Membrane ntigen (EM), Endothelial Markers: Von Willebrand Factor (FVIII related antigen), CD31, CD34 Muscle Markers: Smooth Muscle ctin Desmin Urological & Prostatic Markers: Prostate specific antigen Prostate specific acid phosphatase LP34 or Beta 34E12 Cytokeratin 7 Cytokeratin 20 Cytokeratin 5 or 5/6 P63 or P63/Racemase cocktail Neuroendocrine Markers: Chromogranin Neuron Specific Enolase (NSE) Synaptophysin PGP 9.5 Mesothelial Markers: Carcinoembryonic ntigen (CE) U-1 Ber-EP4 HBME-1 Cytokeratin 5/6 Calretinin Thrombomodulin ssessment Manager: JR1 Page 2 of 7
3 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for (cont d) General Pathology (cont d) Melanoma Markers (apart from S-100): HMB45 or Melan Lymphoid Markers: T-Cell markers e.g.cd3 B-Cell markers e.g. CD20, CD79a Ig light chains (occasional request only): Leucocyte Common ntigen (CD45) CD68 Miscellaneous: Thyroglobulin Ki-67 or MIB1 Human Chorionic Gonadotrophin (HCG) Calcitonin, CD56, TTF1, WT1 Breast Pathology (Hormonal Receptors) Oestrogen receptor (ER) Progesterone receptor (PR) & B Breast Pathology (HER2) HER-2/Neu & B ssessment Manager: JR1 Page 3 of 7
4 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for Lymphoid Pathology lk-1 bcl-2 Bcl-6 CD1a CD2 CD4 CD5 CD8 CD10 CD15 CD20 CD21 CD23 CD30 CD35 CD43 CD56 CD68 CD79a Cyclin D1 IgD IgM Ig light chains Ki-67/MIB1 Mast Cell tryptase Terminal deoxynucleotidyle transferase (Tdt) ssessment Manager: JR1 Page 4 of 7
5 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for Neuropathology Neurological & Neuroendocrine Markers: Neurofilament Protein (NFP) Glial Fibrillary cidic Protein (GFP) Neuron Specific Enolase (NSE) Chromogranin S-100 Protein Growth Hormone (GH) drenocorticotrophic Hormone (CTH) Follicle Stimulating Hormone (FSH) Luteinizing Hormone (LH) Thyroid Stimulating Hormone (TSH) Prolactin Beta-amyloid Ubiquitin Tau-protein Markers of Metastatic Disease: Cytokeratin Leucocyte Common ntigen (LC) Prostate Specific ntigen/prostate Specific cid Phosphatase Desmin ssessment Manager: JR1 Page 5 of 7
6 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for, cell blocks or cytospins Cytopathology Lymphoma Markers: CD3 CD20 CD45 Mesothelioma Markers: HBME-1 Calretinin Thrombomodulin Cytokeratin 5/6 denocarcinoma EM/HMFG-2 Cytokeratins MOC-31 Melanoma Markers: S-100 HMB45, Melan GIST (limentary Tract) CD117 CD34 S100 Desmin DOG-1 SM Lynch Syndrome (HNPCC) (limentary Tract) MLH1 MSH2 MSH6 PMS2 manual available online: ssessment Manager: JR1 Page 6 of 7
7 Schedule of ccreditation United Kingdom ccreditation Service ccredited to University College London, operating UK NEQS for Gastric HER2 IHC HER2 for IHC manual available online: & B Breast HER2 ISH (Interpretive and Technical) HER2 ISH END ssessment Manager: JR1 Page 7 of 7
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