Michael Birt, PhD Director, Center for Sustainable Health, The Biodesign Institute at ASU Executive Director, Pacific Health Summit

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1 Leadership Raymond DuBois, MD, PhD Executive Director, The Biodesign Institute at ASU Dalton Chair, College of Health Solutions Co-Leader, Cancer Prevention Program, Mayo Clinic Arizona Ray DuBois is an internationally renowned expert in colorectal cancer. In addition to leading the Biodesign Institute, DuBois maintains his own laboratory at the Biodesign Institute to examine inflammation and its impact on cancer progression. Michael Birt, PhD Director, Center for Sustainable Health, The Biodesign Institute at ASU Executive Director, Pacific Health Summit Michael Birt strives to sustain health through the integration of molecular and behavioral metrics to improve patient outcomes and lower health care costs. He founded two leading businesses in Asia in biomedical business development and in advertising and market research. Roy Curtiss III, PhD Director, Center for Infectious Diseases and Vaccinology, The Biodesign Institute at ASU Professor, College of Liberal Arts and Sciences, School of Life Sciences Roy Curtiss develops live vaccines to reduce morbidity and mortality caused by infectious diseases in fish, poultry, swine, cattle and humans. His team designs safe salmonella vectors to protect populations against pathogens. Rolf Halden, PhD PE Director, Center for Environmental Security, The Biodesign Institute at ASU Professor, Ira A. Fulton Schools of Engineering, School of Sustainable Engineering and the Built Environment Rolf Halden is a noted expert in monitoring of mass-produced chemicals and strategies to remove environmental toxins and protect human health

2 Leland Hartwell, PhD Chief Scientist, Center for Sustainable Health, The Biodesign Institute at ASU Virginia G. Piper Chair in Personalized Medicine Professor, Ira A. Fulton Schools of Engineering, School of Biological and Health Systems Engineering, and Mary Lou Fulton Teachers College Hartwell was awarded the Nobel Prize in physiology or medicine in 2001 for his discoveries of a specific class of genes that control the cell cycle. He is currently pursuing ways to improve molecular diagnostics to benefit human health. Sidney Hecht, PhD Director, Center for BioEnergetics, The Biodesign Institute at ASU Sidney Hecht researches diseases caused by defects in the body s energy production processes. He was instrumental in developing the cancer therapy Hycamtin (topotecan), to treat ovarian and lung cancer, and the anti-tumor agent bleomycin. Roger Johnson, PhD Director of Strategic Initiatives, The Biodesign Institute at ASU Roger Johnson is an engineer, inventor and research scientist, who leads Biodesign s Office of Strategic Initiatives. He pursues partnership opportunities between research teams and clinical and industry collaborators. Stephen Johnston, PhD Co-Director, Center for Innovations in Medicine, The Biodesign Institute at ASU Professor, College of Liberal Arts and Sciences, School of Life Sciences Stephen Johnston focuses on innovative solutions to fundamental problems in biomedicine. One of his major projects includes developing a universal, preventative cancer vaccine. He co-founded the company HealthTell in 2010.

3 Joshua LaBaer, MD, PhD Director, Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute at ASU Virginia G. Piper Chair in Personalized Medicine Joshua LaBaer is one of the nation s foremost investigators in the rapidly expanding field of personalized medicine. His efforts involve the discovery and validation of biomarkers unique molecular fingerprints of disease that can provide early warning for those at risk of major illnesses, including cancer and diabetes. Stuart Lindsay, PhD Director, Center for Single Molecule Biophysics, The Biodesign Institute at ASU Edward and Nadine Carson Presidential Chair in Physics Regents Professor, College of Liberal Arts and Sciences, Department of Physics and Department of Chemistry and Biochemistry Stuart Lindsay studies how living things work by exploring the molecules that make cells and higher organisms function. Much of his work is aimed at faster diagnosis and an understanding of the molecular basis of disease. He holds 29 U.S. patents and co-founded Molecular Imaging Corporation in 1993, which was acquired by Agilent Technologies. Deirdre Meldrum, PhD Director, Center for Biosignatures and Discovery Automation, The Biodesign Institute at ASU ASU Senior Scientist, Professor, Ira A. Fulton Schools of Engineering, School of Electrical, Computing, and Energy Engineering Deirdre Meldrum engineers devices that explore cell production and cell death to better understand diseases such as cancer, heart disease, stroke and inflammation. Randolph Nesse, MD Director, Center for Evolution, Medicine and Public Health, The Biodesign Institute at ASU Professor, College of Liberal Arts and Sciences, School of Life Sciences Randolph Nesse is one of the world s preeminent researchers in the field of evolutionary medicine. His focus is on how natural selection shaped the capacity for high and low moods and the regulation of mood and anxiety. Nesse is the author of the The Dawn of Darwinian Medicine and the book Why We Get Sick: The New Science of Darwinian Medicine.

4 Bruce Rittmann, PhD Director, Swette Center for Environmental Biotechnology, The Biodesign Institute at ASU Regents Professor, Ira A. Fulton Schools of Engineering, School of Sustainable Engineering and the Built Environment Distinguished Sustainability Scientist, Global Institute of Sustainability Bruce Rittmann is an international leader in managing microbial communities. Rittmann s work is leading to new ways to clean up pollution, treat water, capture renewable energy, and improve human health. Cheryl Selinsky, PhD Senior Director and Chief Operating Officer, The Biodesign Institute at ASU Cheryl Selinsky directs all operational and financial aspects for the Biodesign Institute. She has 20 years of experience in research and technology development and holds a patent on a method for enhancing immune responses to cancer. Nongjian Tao, PhD Director, Center for Bioelectronics and Biosensors, The Biodesign Institute at ASU Professor, Ira A. Fulton Schools of Engineering, School of Electrical, Computer and Energy Engineering Nongjian NJ Tao develops extremely sensitive sensors to accurately detect harmful chemicals that are a threat to the environment, human health and national security. Neal Woodbury, PhD Co-Director, Center for Innovations in Medicine, The Biodesign Institute at ASU Neal Woodbury is developing a diagnostic technology that continuously monitors an individual s health status in real time. He co-founded the company HealthTell in 2010.

5 Hao Yan, PhD Director, Center for Molecular Design and Biomimicry, The Biodesign Institute at ASU Inaugural Milton Glick Distinguished Professor of Chemistry and Biochemistry Hao Yan is designing programmable nanomaterials to enable miniaturized electronics and more precise delivery of medicine. He builds these materials with short DNA segments that self-assemble into desired shapes. Scientists Karen Anderson, MD, PhD Associate Professor, Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute at ASU Associate Professor, School of Life Sciences Oncologist and Associate Professor of Medicine, Mayo Clinic Arizona Karen Anderson is focused on understanding how the body s immune response can be used to detect and alter cancer development. Her team identifies ways to stimulate an immune response to work harder or smarter to attack cancer cells. Charles Arntzen, PhD Professor, Center for Infectious Diseases and Vaccinology, The Biodesign Institute at ASU Regents Professor Florence Ely Nelson Presidential Endowed Chair Charles Arntzen is a pioneer in the development of plant-based vaccines for the prevention of human and agricultural diseases. He uses plant biotechnology to express pharmacologically active products in transgenic plants. From he served as a member of President George W. Bush s Council of Advisors on Science & Technology in the Office of Science and Technology Policy, and in 2004 was appointed by the President to the National Nanotechnology Oversight Board from Chad Borges, PhD Assistant Professor, Virginia G. Piper Center for Personalized Diagnostics Chad Borges applies mass spectrometry to blood samples to find alterations in proteins that may be signals of lung cancer and other diseases. He helped establish the Olympic-level certified Sports Medicine Research and Testing Laboratory with his expertise of hair absorption of doping drugs.

6 John Chaput, PhD Associate Professor, Evolutionary Medicine and Informatics, The Biodesign Institute at ASU Associate Professor, College of Liberal Arts and Sciences, Chemistry and Biochemistry John Chaput generates tailor-made molecules as potential tools for molecular medicine and to better understand the function of human genes and proteins. Chris Diehnelt, PhD Assistant Research Professor The Biodesign Institute, Innovations in Medicine Chris Deihnelt is one of the inventors of synbody technology that leverages the characteristics of naturally occurring antibodies and engineers synthetic versions of these proteins that can be delivered to patients to target infectious agents with more precision than a natural antibody. Erica Forzani, PhD Deputy Director, Center for Bioelectronics and Biosensors, The Biodesign Institute at ASU Assistant Professor; School for Engineering of Matter, Transport, and Energy Ira A. Fulton Schools of Engineering Erica Forzani develops chemical and biological sensors and integrates them into wireless, noninvasive and inexpensive devices. She is focused on health applications and environmental health and safety. Rosa Krajmalnik-Brown, PhD Assistant Professor, Swette Center for Environmental Biotechnology Department of civil and Environmental Engineering, Ira A. Fulton Schools of Engineering Rosa Krjmalnik-Brown uses new genomic-based tools to uncover the capacity of microscopic organisms to clean water, produce energy and positively impact human health. Her work also focuses on uncovering how the microorganisms found in the gut influence digestive issues in children with autism spectrum disorders.

7 Doug Lake, PhD Associate Professor, Virginia G. Piper Center for Personalized Diagnostics, The Biodesign Institute at ASU School of Life Sciences Doug Lake studies how the human immune system attacks cancer. His current research focuses on an enzyme that helps tumor cells evade the immune system and spread into neighboring tissues during metastasis. Randy Nelson, PhD Research Professor, Molecular Biomarkers Laboratory, The Biodesign Institute at ASU Affiliate Professor, College of Liberal Arts and Sciences, Department of Physics and Department of Chemistry and Biochemistry Randy Nelson is an expert in the field of proteomics. He studies alterations in proteins that are indicative of disease using mass spectrometry methods developed by his research team and commercialized through his company, Intrisinic Bioprobes, now part of Thermo Fisher Scientific. Nelson s lab is currently focused on cancer, cardiovascular disease and diabetes. Cèsar Torres, PhD Assistant Professor, Swette Center for Environmental Biotechnology, The Biodesign Institute at ASU Assistant Professor, School for Engineering of Matter, Transport and Energy, Ira A. Fulton Schools of Engineering Cèsar is a leader in developing and optimizing fuel cells that run on microbes to produce electrical energy from waste.

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