Milan, Italy October 2013

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1 PRELIMINARY PROGRAMME Preceptorship on MRI in multiple sclerosis Milan, Italy October 2013

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3 Aim of the course The goal of this activity is to educate physicians regarding the application and the relevance of conventional and advanced magnetic resonance imaging (MRI) techniques for the management of multiple sclerosis (MS). Together with laboratory tests and neurophysiological studies, MRI findings are central to make a diagnosis of MS, and it is even more important in monitoring disease progression and assessing efficacy of treatment in clinical trials as well as at an individual patient level. Plenary lectures given by wordlwide known experts in the use of MRI in MS. Guided tours at the Neuroimaging Research Unit and at the Departments of Neuroradiology and Neurology will be provided to participants in order to understand better the wide range of application of MRI techniques in MS management. Learning objectives The main topics of the course will be focused on: MRI in the diagnosis of MS Application of structural and functional MRI techniques in the understanding of MS pathophysiology and evolution Relevance of MRI studies in the evaluation of treatment response in clinical practice and clinical trials Target audience Young clinicians and scientists currently involved in MS management and radiologists interested in MS. Accreditation An application will be made to the EACCME and to the Italian Ministry of Health for the CME accreditation of the Serono Symposia International Foundation Preceptorship in MRI on multiple sclerosis to be held in Milan, Italy on October All Serono Symposia International Foundation programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. All Serono Symposia International Foundation programmes are made possible thanks to the unrestricted Educational grants received from: Arseus Medical, Besins Healthcare, Bristol-Myers Squibb, Celgene, Centre d Esclerosi Multiple de Catalunya (Vall d'hebron University Hospital), Centre Hépato- Biliaire, Hôpital Paul Brousse, ComtecMed, Congrex, Croissance Conseil, Cryo-Save, Datanalysis, Dos33, Esaote, European Society of Endocrinology, Ferring, Fondazione Humanitas, Fundación IVI, GE Healthcare, GlaxoSmithKline Pharmaceuticals, IPSEN, Johnson & Johnson Medical, ISFP International Society for Fertility Preservation, ISMH International Society of Men s Health, K.I.T.E., Karl Storz, Lumenis, Merck Serono Group, PregLem, Richard Wolf Endoscopie, Sanofi-Aventis, Stallergenes, Stopler, Teva Pharma, Toshiba Medical Systems, Université Catholique de Louvain (UCL), University of Catania. 1

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5 Scientific organizer Massimo Filippi Neuroimaging Research Unit Institute of Experimental Neurology Division of Neuroscience San Raffaele Scientific Institute Vita-Salute San Raffaele University Milan, Italy Serono Symposia International Foundation designed this programme in partnership with the Scientific Institute and University Vita-Salute San Raffaele. We value your opinion! We are continually trying to develop and improve our educational initiatives to provide you with cutting-edge learning activities. During this live educational event you will be asked to answer a real time survey and prior to this educational event and after you will be receiving an online survey to help us to better tailor our future educational initiatives. We thank you for participating! Scientific secretariat Serono Symposia International Foundation Salita di San Nicola da Tolentino, 1/b Rome, Italy Project Manager: Alessia Addessi T +39-(0) F +39-(0) info@seronosymposia.org Medical Advisor: Federica Cerri Serono Symposia International Foundation is a Swiss Foundation with headquarters in 14, rue du Rhône, 1204 Geneva, Switzerland Organizing secretariat Meridiano Congress International Via Sapri, Rome, Italy Congress Coordinator: David H. Slangen T +39 (0) F +39 (0) d.slangen@meridiano.it 3

6 List of speakers

7 Federica Agosta Neuroimaging Research Unit Institute of Experimental Neurology Division of Neuroscience San Raffaele Scientific Institute Vita-Salute San Raffaele University Milan, Italy Giancarlo Comi Department of Neurology Institute of Experimental Neurology University Vita-Salute San Raffaele Milan, Italy Nicola De Stefano Neurology and Neurometabolic Unit Department of Neurological and Behavioral Sciences University of Siena Siena, Italy Gilles Edan Centre Hospitalier Universitaire de Rennes Rennes, France Andrea Falini Department of Neuroradiology at the Scientific Institute and University Vita-Salute San Raffaele Milan, Italy Franz Fazekas Department of Neurology Medical University Graz Graz, Austria Massimo Filippi Neuroimaging Research Unit Institute of Experimental Neurology Division of Neuroscience San Raffaele Scientific Institute Vita-Salute San Raffaele University Milan, Italy 5

8 Jeroen J.G. Geurts Department of Anatomy & Neurosciences Section of Clinical Neuroscience VU University Medical Center Amsterdam, The Netherlands Maria Assunta Rocca Neuroimaging Research Unit Institute of Experimental Neurology Division of Neuroscience Scientific Institute and University San Raffaele Milan, Italy Jaume Sastre-Garriga Multiple Sclerosis Center of Catalonia Unit of Clinical Neuroimmunology Vall d Hebron University Hospital Barcelona, Spain Ahmed Toosy Department of Brain Repair and Rehabilitation UCL Institute of Neurology, UCL London, UK Paola Valsasina Neuroimaging Research Unit Institute of Experimental Neurology Division of Neuroscience San Raffaele Scientific Institute Vita-Salute San Raffaele University Milan, Italy 6

9 Scientific programme

10 Scientific programme October 2013 Tuesday - 24 October Serono Symposia International Foundation (SSIF) opening and introduction G. Comi (Italy), M. Filippi (Italy) Real time survey The role of imaging techniques in clinical neurology M. Filippi (Italy) The clinical work up of patients suspected of having MS F. Fazekas (Austria) Individualized treatment in patients with MS G. Comi (Italy) Coffee break The MRI criteria for diagnosing MS J. Sastre-Garriga (Spain) MRI and the differential diagnosis in patients suspected of having MS A. Falini (Italy) Case studies on diagnosis/differential diagnosis Real time survey Lunch Guided visit to the Neuroimaging Research Unit and Neuroimmunology Unit 8

11 Friday - 25 October Real time survey Understanding MS evolution using structural MR techniques J.J.G. Geurts (The Netherlands) Understanding MS evolution using functional MR techniques M.A. Rocca (Italy) Optic nerve MRI A. Toosy (UK) Spinal cord MRI P. Valsasina (Italy) Coffee break MRI and cognition F. Agosta (Italy) Future MR markers to monitor MS N. De Stefano (Italy) MRI and clinical trials G. Edan (France) Real time survey Concluding remarks and end of the course Lunch Guided visit to the Neuroimaging Research Unit and Neuroimmunology Unit 9

12 General information Venue The workshop will take place at the: Centro Congressi San Raffaele Aula Caravella Nina Via Olgettina Milan, Italy Language The official language of the course will be English. Registration fee Full registration fee is A 450,00. This fee includes: Scientific sessions Coffee breaks and luncheons Dinner on 24 October 2013 Educational materials Certificate of attendance Registration fee without dinner is A 370,00. For any registration and/or accommodation requirement please contact our Organizer Secretariat: Meridiano Congress International Congress Coordinator: David H. Slangen T +39 (0) F +39 (0) d.slangen@meridiano.it Register to Serono Symposia International Foundation website: follow us on SSIF_Neurology 10

13 Serono Symposia International Foundation (SSIF) MS Preceptorship conferences, aim to update young physicians about the very latest developments from leading international scientists and clinicians. SSIF is seeking to capture their energy and enthusiasm by creating an MS Alumni Program a lasting community, which will continue to share ideas and best practice well into the future. Three main European MS centres will be involved in the program: - Multiple Sclerosis Centre of Catalonia, Cem-cat Barcelona, Spain - Institute of Experimental Neurology Vita-Salute San Raffaele University, Milan, Italy - Valens Clinic Rehabilitation Center, Valens, Switzerland Why is the Alumni Program so important? The effective treatment of MS is one of the greatest of clinical challenges. SSIF believes that young physicians need every opportunity, now and in the future, to share their knowledge, to keep up to date and to have access to internationally respected mentors. Be part of the MS Alumni Program! You qualify to be an alumnus if you have attended one of the SSIF's Preceptorships. Ask to be recontacted later on with more news on this exiting opportunity! The MS Alumni Program: creating a community of excellence

14 Serono Symposia International Foundation Serono Symposia International Foundation is an independent, non-profit organization dedicated to the Continuing Medical Education (CME) of scientists, physicians, nurses, pharmacists and other healthcare professionals through state-of-the-art clinical and scientific activities designed to enhance patient care and improve healthcare outcomes. Serono Symposia International Foundation conferences and workshops provide unique opportunities where physicians and healthcare professionals can meet with the world leading experts to learn about the latest scientific developments as well as exchange ideas in an open and stimulating environment. Serono Symposia International Foundation offers different formats of live educational events: International Conferences: CME accredited International Conferences updating and evaluating the newest scientific topics. Academia: CME accredited International Training Courses mainly addressed to junior scientists/physicians who want to specialize in a specific field. Preceptorship: CME International Workshops based on theory and practice sessions. Tutors and participants are able to directly share practice and knowledge. If you wish to learn more about Serono Symposia International Foundation s educational activities, please visit: The website will provide you with: A calendar of upcoming Serono Symposia International Foundation events Online CME courses Symposia reviews Presentations from past events Abstracts Literature reviews Glossaries... and a lot more!

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16 Improving the patient's life through medical education Serono Symposia International Foundation Headquarters 14, Rue du Rhône Geneva, Switzerland Representative Office Salita di San Nicola da Tolentino 1/b Rome, Italy T +39.(0) F +39.(0) Copyright Serono Symposia International Foundation, All rights reserved.

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