Genomics and Health Data Standards: Lessons from the Past and Present for a Genome-enabled Future
|
|
- Matilda Summers
- 8 years ago
- Views:
Transcription
1 Genomics and Health Data Standards: Lessons from the Past and Present for a Genome-enabled Future Daniel Masys, MD Professor and Chair Department of Biomedical Informatics Professor of Medicine Vanderbilt University School of Medicine Principal Investigator electronic Medical Records and Genomics (emerge) Coordination Center
2 Topics The emerge consortium: on the frontier of genomes and phenotypes derived from clinical sources Lessons for future standards learned from the last 40 years of biomedical informatics
3 RFA HG : Genome-Wide Studies in Biorepositories with Electronic Medical Record Data 2007 NIH Request for Applications from the National Human Genome Research Institute The purpose of this funding opportunity is to provide support for investigative groups affiliated with existing biorepositories to develop necessary methods and procedures for, and then to perform, if feasible, genome-wide studies in participants with phenotypes and environmental exposures derived from electronic medical records, with the aim of widespread sharing of the resulting individual genotype-phenotype data to accelerate the discovery of genes related to complex diseases.
4 emerge: an NHGRI-funded consortium for Biobanks linked to EMR data Consortium members Group Health of Puget Sound Marshfield Clinic Mayo Clinic Northwestern University Vanderbilt University Condition of NIH funding: contribute genomic and EMR-derived phenotype data to dbgap database at NCBI
5 Dementia Cataracts Type II diabetes Peripheral vascular disease Coordinating center QRS duration
6 Each site includes DNA linked to electronic medical records Each project includes community engagement, genome science, natural language processing capability for EMR data Research plans include identifying a phenotype of interest in 3,000 subjects and conduct of a genomewide association study at each center: Σ=18,000 Supplemental funding provided for cross-network phenotypes
7 Supplement phenotypes using genotyped samples from primary phenotypes* *The benefit of data from routine clinical testing results recorded in EHR RBC/WBC Diabetic Retinopathy Lipid Levels & Height GFR GHC 3, ,114 1,713 Marshfield 3, ,693 3,929 Mayo 3, ,175 3,340 NU 2, ,816 1,485 VU 2,650 1,449 1,631 2,679
8 Informatics Issues in emerge Determination of comparability of patient populations across institutions Data exchange standards for phenotype data Representation of change over time (repeated measures) and clinical uncertainty for EMR-derived observations (definite probable possible for assertion and negation) Re-identification potential of clinical data and associated samples: maximizing scientific value while complying with federal privacy protection policies
9 Lessons learned from emerge Structured data alone (ICD9 codes, labs, meds) is not enough to accurately define clinical phenotypes in EMR data. Natural language processing of clinician notes improves both sensitivity and specificity of phenotype selection logic Once selection logic has been validated at one site, it can be successfully shared as pseudocode and implemented at other sites with widely varying EMR systems architectures
10 The problem with ICD codes ICD code sets contain both false negatives and false positives False negatives: Outpatient billing limited to 4 diagnoses/visit Outpatient billing done by physicians (e.g., takes too long to find the unknown ICD9) Inpatient billing done by professional coders: omit codes that don t pay well can only code problems actually explicitly mentioned in documentation False positives Diagnoses evolve over time -- physicians may initially bill for suspected diagnoses that later are determined to be incorrect Billing the wrong code (perhaps it is easier to find for a busier clinician) Physicians may bill for a different condition if it pays for a given treatment Example: Anti-TNF biologics (e.g., infliximab) originally not covered for psoriatic arthritis, so rheumatologists would code the patient as having rheumatoid arthritis
11 Observations about clinical genomics Genomic data is the current poster child for complexity in healthcare No practitioner can absorb and remember more than a tiny fraction of the knowledge base of human variation Therefore, computerized clinical decision support is the only effective way to insert genomic variation-based guidance into clinical care
12 Need for Patient-Specific Decision Support Assistance Facts per Decision Proteomics and other effector molecules Functional Genetics: Gene expression profiles Decisions by clinical phenotype i.e., traditional health care Structural Genetics: e.g. SNPs, haplotypes Human Cognitive Capacity
13 Observations about genomic data in general Predictably, some future uses of genomic data will be so creative that nobody could have predicted them. Raw data e.g., primary DNA sequence, specific SNP values, should be retained when adding clinical interpretations, not discarded in the synthesis and reporting of those interpretations
14 Lessons learned about standards The most successful and widely used standards are messaging and communications standards e.g., TCP/IP, http, smtp, ftp, HL7. Knowledge representation standards tend to be widely used only if driven by financial processes, government mandate (e.g., ICD-9), or sustained government investment (e.g., MeSH, SNOMED, UMLS Metathesaurus)
15 Lessons learned about standards, cont d Familiar and usable wins over theoretically correct but too complex e.g., HL7 v.2 vs. v.3 Lindberg s axiom: Systems that get used get better.
16 URL:
17 Commander Willard Decker: V'ger... expects an answer. Captain James T. Kirk: An answer? I don't even know the question. Star Trek, the movie 1979
Electronic Medical Records and Genomics: Possibilities, Realities, Ethical Issues to Consider
Electronic Medical Records and Genomics: Possibilities, Realities, Ethical Issues to Consider Daniel Masys, M.D. Affiliate Professor Biomedical and Health Informatics University of Washington, Seattle
More informationIntegration of genomic data into electronic health records
Integration of genomic data into electronic health records Daniel Masys, MD Affiliate Professor Biomedical & Health Informatics University of Washington, Seattle Major portion of today s lecture is based
More informationMajor US Genomic Medicine Programs: NHGRI s Electronic Medical Records and Genomics (emerge) Network
Major US Genomic Medicine Programs: NHGRI s Electronic Medical Records and Genomics (emerge) Network Dan Roden Member, National Advisory Council For Human Genome Research Genomic Medicine Working Group
More informationOutcome Data, Links to Electronic Medical Records. Dan Roden Vanderbilt University
Outcome Data, Links to Electronic Medical Records Dan Roden Vanderbilt University Coordinating Center Type II Diabetes Case Algorithm * Abnormal lab= Random glucose > 200mg/dl, Fasting glucose > 125 mg/dl,
More informationOf Codes, Genomes, and Electronic Health Records: It s Only Sensitive If It Hurts When You Touch It
Of Codes, Genomes, and Electronic Health Records: It s Only Sensitive If It Hurts When You Touch It Daniel Masys, M.D. Affiliate Professor Biomedical and Health Informatics University of Washington Seattle,
More informationAnonymization of Administrative Billing Codes with Repeated Diagnoses Through Censoring
Anonymization of Administrative Billing Codes with Repeated Diagnoses Through Censoring Acar Tamersoy, Grigorios Loukides PhD, Joshua C. Denny MD MS, and Bradley Malin PhD Department of Biomedical Informatics,
More informationStandardized Representation for Electronic Health Record-Driven Phenotypes
Standardized Representation for Electronic Health Record-Driven Phenotypes April 8, 2014 AMIA Joint Summits for Translational Research Rachel L. Richesson, PhD Shelley A. Rusincovitch Michelle M. Smerek
More informationWorkshop on Establishing a Central Resource of Data from Genome Sequencing Projects
Report on the Workshop on Establishing a Central Resource of Data from Genome Sequencing Projects Background and Goals of the Workshop June 5 6, 2012 The use of genome sequencing in human research is growing
More informationEHRs and large scale comparative effectiveness research
EHRs and large scale comparative effectiveness research September 16, 2014 Dana C. Crawford, PhD Associate Professor Epidemiology and Biostatistics Institute for Computational Biology Single Nucleotide
More informationBench to Bedside Clinical Decision Support:
Bench to Bedside Clinical Decision Support: The Role of Semantic Web Technologies in Clinical and Translational Medicine Tonya Hongsermeier, MD, MBA Corporate Manager, Clinical Knowledge Management and
More informationSAP Healthcare Analytics Solutions Provide physicians and researchers access to patient data from various systems in realtime
SAP Healthcare Analytics Solutions Provide physicians and researchers access to patient data from various systems in realtime Stephan Schindewolf, SAP SE, July 13, 2015 Facts per Decision Need Decision
More informationNIH s Genomic Data Sharing Policy
NIH s Genomic Data Sharing Policy 2 Benefits of Data Sharing Enables data generated from one study to be used to explore a wide range of additional research questions Increases statistical power and scientific
More informationTechnical Issues in Aggregating and Analyzing Data from Heterogeneous EHR Systems
Technical Issues in Aggregating and Analyzing Data from Heterogeneous EHR Systems Josh Denny, MD, MS josh.denny@vanderbilt.edu Vanderbilt University, Nashville, Tennessee, USA 2/12/2015 EHR data are dense
More informationPotentials for EHR Phenotyping in SJS/TEN
Potentials for EHR Phenotyping in SJS/TEN Josh Denny, MD, MS josh.denny@vanderbilt.edu Vanderbilt University, Nashville, Tennessee, USA 3/3/2015 emerge goals To perform GWAS using EMR-derived phenotypes
More informationElectronic Phenotyping and Genomic Research
National Human Genome Research Institute Electronic Phenotyping and Genomic Research National Institutes of Health U.S. Department of Health and Human Services National Institutes of Health National Human
More informationThe Use of Patient Records (EHR) for Research
The Use of Patient Records (EHR) for Research Mary Devereaux, Ph.D. Director, Biomedical Ethics Seminars Assistant Director, Research Ethics Program & San Diego Research Ethics Consortium Abstract The
More informationVoluntary Genomic Data Submissions at the U.S. FDA
Voluntary Genomic Data Submissions at the U.S. FDA International Conference on Harmonization Chicago, IL November 9-10, 9 2005 Felix W. Frueh, PhD Associate Director for Genomics Office of Clinical Pharmacology
More informationGenomic Testing: Actionability, Validation, and Standard of Lab Reports
Genomic Testing: Actionability, Validation, and Standard of Lab Reports emerge: Laura Rasmussen-Torvik Reaction: Heidi Rehm Summary: Dick Weinshilboum Panel: Murray Brilliant, David Carey, John Carpten,
More informationHealthcare Professional. Driving to the Future 11 March 7, 2011
Clinical Analytics for the Practicing Healthcare Professional Driving to the Future 11 March 7, 2011 Michael O. Bice Agenda Clinical informatics as context for clinical analytics Uniqueness of medical
More informationIntegration of Genetic and Familial Data into. Electronic Medical Records and Healthcare Processes
Integration of Genetic and Familial Data into Electronic Medical Records and Healthcare Processes By Thomas Kmiecik and Dale Sanders February 2, 2009 Introduction Although our health is certainly impacted
More informationAn EVIDENCE-ENHANCED HEALTHCARE ECOSYSTEM for Cancer: I/T perspectives
An EVIDENCE-ENHANCED HEALTHCARE ECOSYSTEM for Cancer: I/T perspectives Chalapathy Neti, Ph.D. Associate Director, Healthcare Transformation, Shahram Ebadollahi, Ph.D. Research Staff Memeber IBM Research,
More informationA Tech Entrepreneur Meets Academic Pathology
A Tech Entrepreneur Meets Academic Pathology David Nessl, PMP, MBA, Adj. Professor of Business Chief Technology Officer (CTO) Dept. of Pathology / UF PathLabs University of Florida 01/31/2013 A Tech Entrepreneur
More informationOverview. Overarching observations
Overview Genomics and Health Information Technology Systems: Exploring the Issues April 27-28, 2011, Bethesda, MD Brief Meeting Summary, prepared by Greg Feero, M.D., Ph.D. (planning committee chair) The
More informationIncorporating Research Into Sight (IRIS) Essentia Rural Health Institute Marshfield Clinic Penn State University
Incorporating Research Into Sight (IRIS) Essentia Rural Health Institute Marshfield Clinic Penn State University Aim 1. Develop and validate electronic algorithms for ophthalmic conditions and efficacy
More information#Aim2Innovate. Share session insights and questions socially. Genomics, Precision Medicine and the EHR 6/17/2015
Genomics, Precision Medicine and the EHR Making Genomics part of everyday practice Andrew Ury, M.D. CEO and founder, ActX, Inc. June 17, 2015 DISCLAIMER: The views and opinions expressed in this presentation
More informationEnhancing Functionality of EHRs for Genomic Research, Including E- Phenotying, Integrating Genomic Data, Transportable CDS, Privacy Threats
Enhancing Functionality of EHRs for Genomic Research, Including E- Phenotying, Integrating Genomic Data, Transportable CDS, Privacy Threats Genomic Medicine 8 meeting Alexa McCray Christopher G Chute Rex
More informationMedical Informatics An Overview Saudi Board For Community Medicine
Medical Informatics An Overview Saudi Board For Community Medicine Ahmed AlBarrak PhD Medical Informatics Associate Professor of Health Informatics, Family & Community Med, Chairman, Medical Informatics,
More informationBig Data in Biobanking towards targeted medicine
Big Data in Biobanking towards targeted medicine Ronald Stolk Professor Clinical Epidemiology, UMCG Board member Parelsnoer Institute Chief Scientific Officer LifeLines What is a biobank? Systematic collection
More informationTRANSFoRm: Vision of a learning healthcare system
TRANSFoRm: Vision of a learning healthcare system Vasa Curcin, Imperial College London Theo Arvanitis, University of Birmingham Derek Corrigan, Royal College of Surgeons Ireland TRANSFoRm is partially
More informationExecutive Summary Think Research. Using Electronic Medical Records to Bridge Patient Care and Research
Executive Summary Think Research Using Electronic Medical Records to Bridge Patient Care and Research Introduction Letter from Greg Simon, President of FasterCures At FasterCures our mission is to save
More informationMED 2400 MEDICAL INFORMATICS FUNDAMENTALS
MED 2400 MEDICAL INFORMATICS FUNDAMENTALS NEW YORK CITY COLLEGE OF TECHNOLOGY The City University Of New York School of Arts and Sciences Biological Sciences Department Course title: Course code: MED 2400
More informationICD-10-CM The Case for Moving Forward
A Health Data Consulting White Paper 1056 6th Ave S Edmonds, WA 98020-4035 206-478-8227 www.healthdataconsulting.com ICD-10-CM The Case for Moving Forward Joseph C Nichols MD Principal 23 March 2012 THE
More informationBig Data for Population Health
Big Data for Population Health Prof Martin Landray Nuffield Department of Population Health Deputy Director, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery University of Oxford
More informationGenomic Medicine Centers Meeting VII. Summary of Themes Discussed in Keynote and Panel Discussions October 3, 2014
Genomic Medicine Centers Meeting VII Summary of Themes Discussed in Keynote and Panel Discussions October 3, 2014 Meeting Objectives GM 7 will convene key thought leaders in genomic implementation and
More informationGENETIC DATA ANALYSIS
GENETIC DATA ANALYSIS 1 Genetic Data: Future of Personalized Healthcare To achieve personalization in Healthcare, there is a need for more advancements in the field of Genomics. The human genome is made
More informationUsing Big Data to Advance Healthcare Gregory J. Moore MD, PhD February 4, 2014
Using Big Data to Advance Healthcare Gregory J. Moore MD, PhD February 4, 2014 Sequencing Technology - Hype Cycle (Gartner) Gartner - Hype Cycle for Healthcare Provider Applications, Analytics and Systems,
More informationINTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE E15
INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE ICH HARMONISED TRIPARTITE GUIDELINE DEFINITIONS FOR GENOMIC BIOMARKERS, PHARMACOGENOMICS,
More informationThe Future of the Electronic Health Record. Gerry Higgins, Ph.D., Johns Hopkins
The Future of the Electronic Health Record Gerry Higgins, Ph.D., Johns Hopkins Topics to be covered Near Term Opportunities: Commercial, Usability, Unification of different applications. OMICS : The patient
More informationHow Can Institutions Foster OMICS Research While Protecting Patients?
IOM Workshop on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials How Can Institutions Foster OMICS Research While Protecting Patients? E. Albert Reece, MD, PhD, MBA Vice
More informationA Comparison of Hemorrhagic and Ischemic Strokes among Blacks and Whites:
A Comparison of Hemorrhagic and Ischemic Strokes among Blacks and Whites: A Population-Based Study That Will Demonstrate Issues Surrounding EHR Access and Research Brett Kissela, MD, MS Professor Vice-Chair
More informationElectronic Medical Records for Genetic Research: Results of the emerge Consortium
ELECTRONIC MEDICAL RECORDS Electronic Medical Records for Genetic Research: Results of the emerge Consortium Abel N. Kho, 1,2 * Jennifer A. Pacheco, 1 Peggy L. Peissig, 3 Luke Rasmussen, 3 Katherine M.
More informationPersonal Genomes and Ethical Issues. 02-223 How to Analyze Your Own Genome
Personal Genomes and Ethical Issues 02-223 How to Analyze Your Own Genome Declining Cost of Genome Sequencing The genome sequencing is expected to happen rouanely in the near future Schadt, MSB, 2012 The
More informationImplementing CDSMP in an integrated health care system
Implementing CDSMP in an integrated health care system The Group Health experience October 2, 2009 Kimberly Wicklund, MPH Group Health Overview Consumer-governed, non-profit financing and care delivery
More informationUsing EHRs to extract information, query clinicians, and insert reports
Using EHRs to extract information, query clinicians, and insert reports Meghan Baker, MD, ScD NIH HCS Collaboratory EHR working group webinar March 26, 2013 1 E S P V A E R S Electronic Support for Public
More informationGenomics and the EHR. Mark Hoffman, Ph.D. Vice President Research Solutions Cerner Corporation
Genomics and the EHR Mark Hoffman, Ph.D. Vice President Research Solutions Cerner Corporation Overview EHR from Commercial Perspective What can be done TODAY? What could be done TOMORROW? What are some
More informationIntegrating Bioinformatics, Medical Sciences and Drug Discovery
Integrating Bioinformatics, Medical Sciences and Drug Discovery M. Madan Babu Centre for Biotechnology, Anna University, Chennai - 600025 phone: 44-4332179 :: email: madanm1@rediffmail.com Bioinformatics
More informationHL7 Clinical Genomics and Structured Documents Work Groups
HL7 Clinical Genomics and Structured Documents Work Groups CDA Implementation Guide: Genetic Testing Report (GTR) Amnon Shabo (Shvo), PhD shabo@il.ibm.com HL7 Clinical Genomics WG Co-chair and Modeling
More informationVision for the Cohort and the Precision Medicine Initiative Francis S. Collins, M.D., Ph.D. Director, National Institutes of Health Precision
Vision for the Cohort and the Precision Medicine Initiative Francis S. Collins, M.D., Ph.D. Director, National Institutes of Health Precision Medicine Initiative: Building a Large U.S. Research Cohort
More informationCourse Syllabus. Upon completion of all six modules, participants will have:
Course Syllabus COURSE Health Informatics (101) Introduction to Health Informatics (101) COURSE DESCRIPTION Introduction to Health Informatics (101) offers an overview of the field of health informatics
More informationTranslational & Interoperable Health Infostructure - The Servant of Three Masters. Abridged Presentation
Revolutionizing healthcare through independent lifetime health records Towards a universal health information language Translational & Interoperable Health Infostructure - The Servant of Three Masters
More informationEuropean Genome-phenome Archive database of human data consented for use in biomedical research at the European Bioinformatics Institute
European Genome-phenome Archive database of human data consented for use in biomedical research at the European Bioinformatics Institute Justin Paschall Team Leader Genetic Variation / EGA ! European Genome-phenome
More informationElectronic Health Record (EHR) Standards Survey
Electronic Health Record (EHR) Standards Survey Compiled by: Simona Cohen, Amnon Shabo Date: August 1st, 2001 This report is a short survey about the main emerging standards that relate to EHR - Electronic
More informationA Multi-locus Genetic Risk Score for Abdominal Aortic Aneurysm
A Multi-locus Genetic Risk Score for Abdominal Aortic Aneurysm Zi Ye, 1 MD, Erin Austin, 1,2 PhD, Daniel J Schaid, 2 PhD, Iftikhar J. Kullo, 1 MD Affiliations: 1 Division of Cardiovascular Diseases and
More informationImplementing Proactive Pharmacogenetic Testing as a Standard of Care
Implementing Proactive Pharmacogenetic Testing as a Standard of Care Submitted by: James M. Hoffman, Pharm.D., MS, BCPS, Medication Outcomes & Safety Officer, Pharmaceutical Services, Associate Member,
More informationSharing Data from Large-scale Biological Research Projects: A System of Tripartite Responsibility
Sharing Data from Large-scale Biological Research Projects: A System of Tripartite Responsibility Report of a meeting organized by the Wellcome Trust and held on 14 15 January 2003 at Fort Lauderdale,
More informationPractical Development and Implementation of EHR Phenotypes. NIH Collaboratory Grand Rounds Friday, November 15, 2013
Practical Development and Implementation of EHR Phenotypes NIH Collaboratory Grand Rounds Friday, November 15, 2013 The Southeastern Diabetes Initiative (SEDI) Setting the Context Risk Prediction and Intervention:
More informationA National Clinical Decision Support Infrastructure to Enable Genetically-Guided Population Health Management at Scale
A National Clinical Decision Support Infrastructure to Enable Genetically-Guided Population Health Management at Scale September 23, 2010 Kensaku Kawamoto, MD, PhD Assistant Professor Department of Community
More informationSecondary Use of EMR Data View from SHARPn AMIA Health Policy, 12 Dec 2012
Secondary Use of EMR Data View from SHARPn AMIA Health Policy, 12 Dec 2012 Christopher G. Chute, MD DrPH, Professor, Biomedical Informatics, Mayo Clinic Chair, ISO TC215 on Health Informatics Chair, International
More informationTheodoros. N. Arvanitis, RT, DPhil, CEng, MIET, MIEEE, AMIA, FRSM
TRANSFoRm Theodoros. N. Arvanitis, RT, DPhil, CEng, MIET, MIEEE, AMIA, FRSM Biomedical Informatics, Signals & Systems Research Laboratory School of Electronic, Electrical & Computer Engineering College
More informationEnvironmental Health Science. Brian S. Schwartz, MD, MS
Environmental Health Science Data Streams Health Data Brian S. Schwartz, MD, MS January 10, 2013 When is a data stream not a data stream? When it is health data. EHR data = PHI of health system Data stream
More informationTRANSLATIONAL BIOINFORMATICS 101
TRANSLATIONAL BIOINFORMATICS 101 JESSICA D. TENENBAUM Department of Bioinformatics and Biostatistics, Duke University Durham, NC 27715 USA Jessie.Tenenbaum@duke.edu SUBHA MADHAVAN Innovation Center for
More informationSchool of Nursing. Presented by Yvette Conley, PhD
Presented by Yvette Conley, PhD What we will cover during this webcast: Briefly discuss the approaches introduced in the paper: Genome Sequencing Genome Wide Association Studies Epigenomics Gene Expression
More informationThe National Institute of Genomic Medicine (INMEGEN) was
Genome is...... the complete set of genetic information contained within all of the chromosomes of an organism. It defines the particular phenotype of an individual. What is Genomics? The study of the
More informationPrognosis for Healthcare: The Future of Medicine
Prognosis for Healthcare: The Future of Medicine Bruce M. Cohen, M.D., Ph.D. Director, Frazier Research Institute, McLean Hospital President and Psychiatrist in Chief Emeritus, McLean Hospital Robertson-Steele
More informationEHR Data Preservation
Emerging Computational Approaches to Interoperability the Key to Long Term Preservation of EHR Data William W. Stead, M.D. Associate Vice Chancellor for Health Affairs Chief Strategy & Information Officer
More informationMedical Informatics: A Fishing Story
Medical Informatics: A Fishing Story Russ Waitman, PhD Director of Medical Informatics, Associate Professor, Department of Biostatistics Director, Frontiers Biomedical Informatics Assistant Vice Chancellor,
More informationA Primer of Genome Science THIRD
A Primer of Genome Science THIRD EDITION GREG GIBSON-SPENCER V. MUSE North Carolina State University Sinauer Associates, Inc. Publishers Sunderland, Massachusetts USA Contents Preface xi 1 Genome Projects:
More informationContinuity of Care Record (CCR) The Concept Paper of the CCR
Continuity of Care Record (CCR) The Concept Paper of the CCR Version 2.1b Note: Development of the CCR is an ongoing process. Thus, the following information, in particular that related to the CCR s content,
More informationReasoning / Medical Context / Physicians Area of Competence
Medical Informatics Learning Objectives for Undergraduate Medical Education created by the project group "Medical Informatics Education in Medicine" (chairs: M. Dugas, J. Stausberg) of the German Association
More informationGenetic Alliance BioBank: A Virtual Tour of Registry Solutions to Accelerate Research February 22, 2010
Genetic Alliance BioBank: A Virtual Tour of Registry Solutions to Accelerate Research February 22, 2010 Liz Horn Genetic Alliance Posted in the Resource Repository at: http://www.resourcerepository.org/documents/1872/geneticalliancebiobank:avirtualto
More informationIssues with Tissues. Bertha delanda Celia Molvin/Kevin Murphy Research Compliance Office Stanford University
Issues with Tissues Bertha delanda Celia Molvin/Kevin Murphy Office Stanford University What are Tissues? Organic material removed from a living individual. Including biological samples For example, Blood
More informationElectronic Health Records - An Overview - Martin C. Were, MD MS March 24, 2010
Electronic Health Records - An Overview - Martin C. Were, MD MS March 24, 2010 Why Electronic Health Records (EHRs) EHRs vs. Paper Components of EHRs Characteristics of a good EHRs A Kenyan EHRs implementation
More informationIntegrated Biomedical and Clinical Research Informatics for Translational Medicine and Therapeutics
Integrated Biomedical and Clinical Research Informatics for Translational Medicine and Therapeutics J. Richard Landis, PhD Robert M. Curley, MS Gregg Fromell, MD Center for Clinical Epidemiology and Biostatistics
More informationDraft Pan-Canadian Primary Health Care Electronic Medical Record Content Standard, Version 2.0 (PHC EMR CS) Frequently Asked Questions
December 2011 Draft Pan-Canadian Primary Health Care Electronic Medical Record Content Standard, Version 2.0 (PHC EMR CS) Frequently Asked Questions Background and History What is primary health care?
More informationLeading Genomics. Diagnostic. Discove. Collab. harma. Shanghai Cambridge, MA Reykjavik
Leading Genomics Diagnostic harma Discove Collab Shanghai Cambridge, MA Reykjavik Global leadership for using the genome to create better medicine WuXi NextCODE provides a uniquely proven and integrated
More informationHuman Research Protection Program University of California, San Diego ISSUES ON DNA AND INFORMED CONSENT
Human Research Protection Program University of California, San Diego ISSUES ON DNA AND INFORMED CONSENT Regulatory changes will occur for investigators studying human DNA The recent acceleration and widening
More informationUnderstanding Diagnosis Assignment from Billing Systems Relative to Electronic Health Records for Clinical Research Cohort Identification
Understanding Diagnosis Assignment from Billing Systems Relative to Electronic Health Records for Clinical Research Cohort Identification Russ Waitman Kelly Gerard Daniel W. Connolly Gregory A. Ator Division
More informationA New Paradigm for Large, Simple Trials Based on Electronic Health Records
A New Paradigm for Large, Simple Trials Based on Electronic Health Records KyungMann Kim kmkim@biostat.wisc.edu University of Wisconsin-Madison, Madison, WI, USA May 20, 2013 Outline Introduction New Initiatives
More informationPredictive Analytics Drives Population Health Management
Predictive Analytics Drives Population Health Management March 1, 2016 David Seo, MD University of Miami Health System AVP IT Clinical Applications and CMIO Chitra Raghu Lockheed Martin Program Manager
More informationITT Advanced Medical Technologies - A Programmer's Overview
ITT Advanced Medical Technologies (Ileri Tip Teknolojileri) ITT Advanced Medical Technologies (Ileri Tip Teknolojileri) is a biotechnology company (SME) established in Turkey. Its activity area is research,
More informationescience and Post-Genome Biomedical Research
escience and Post-Genome Biomedical Research Thomas L. Casavant, Adam P. DeLuca Departments of Biomedical Engineering, Electrical Engineering and Ophthalmology Coordinated Laboratory for Computational
More informationDisclosure slide. Objectives. The Meaningful Use of EMR. The Meaningful Use of EMR. The Meaningful Use of EMR. Peter Cherouny, M.D.
Disclosure slide WAPC 2012 42 nd Annual Statewide Perinatal Conference Clinical Issues Update Green Bay, WI April 15-17, 2012 Peter Cherouny, M.D. Nothing to disclose The Meaningful Use of Electronic Health
More informationWorldwide Collaborations in Molecular Profiling
Worldwide Collaborations in Molecular Profiling Lillian L. Siu, MD Director, Phase I Program and Cancer Genomics Program Princess Margaret Cancer Centre Lillian Siu, MD Contracted Research: Novartis, Pfizer,
More informationHow To Change Medicine
P4 Medicine: Personalized, Predictive, Preventive, Participatory A Change of View that Changes Everything Leroy E. Hood Institute for Systems Biology David J. Galas Battelle Memorial Institute Version
More information2011 CMIO and Physician IT Survey Report
2011 CMIO and Physician IT Survey Report Facts, Salaries and Advice from Physician IT Leaders Factors Demanding Clinical IT Leadership Federal money and mandate tied to Meaningful Use Clinical automation
More informationHow To Use Centricity Emr
Centricity Electronic Medical Record Complete information, one location Turn information into insight Imagine being able to raise the bar on patient care safety and quality. And find the information you
More informationHow To Transition From Icd 9 To Icd 10
ICD-10 FAQs for Doctors What is ICD-10? ICD-10 is the 10 th revision of the International Classification of Diseases (ICD), used by health care systems to report diagnoses and procedures for purposes of
More informationSMART-on-FHIR Genomics: Enabling Precision Medicine by Bridging Clinical and Genomic Information
SMART-on-FHIR Genomics: Enabling Precision Medicine by Bridging Clinical and Genomic Information Presented by: Gil Alterovitz Assistant Professor, Harvard Medical School and Computational Health Informatics
More informationLifeLines Cohort Study. Salome Scholtens, Manager Research Office
LifeLines Cohort Study Salome Scholtens, Manager Research Office What is LifeLines? Biobank» LifeLines Cohort & Biorepository 165,000 participants at least 30 years follow-up Three generation design Northern
More informationBuilding open source safety-critical medical device platforms and Meaningful Use EHR gateways
Building open source safety-critical medical device platforms and Meaningful Use EHR gateways Inherent connectivity creates significant opportunities in medical science Who is Shahid? 20+ years of software
More informationPresenting data: how to convey information most effectively Centre of Research Excellence in Patient Safety 20 Feb 2015
Presenting data: how to convey information most effectively Centre of Research Excellence in Patient Safety 20 Feb 2015 Biomedical Informatics: helping visualization from molecules to population Dr. Guillermo
More informationMaher Khelifi. A thesis submitted in partial fulfillment of the requirements for the degree of. Master of Science. University of Washington
Design recommendations for Pharmacogenomics Clinical Decision Support Systems Maher Khelifi A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science University
More informationIntroduction to Information and Computer Science: Information Systems
Introduction to Information and Computer Science: Information Systems Lecture 1 Audio Transcript Slide 1 Welcome to Introduction to Information and Computer Science: Information Systems. The component,
More informationFactors for success in big data science
Factors for success in big data science Damjan Vukcevic Data Science Murdoch Childrens Research Institute 16 October 2014 Big Data Reading Group (Department of Mathematics & Statistics, University of Melbourne)
More informationRecords and Clinical Trials
Integrating Electronic Health Records and Clinical Trials The Children s Hospital An Examination of Pragmatic Issues Affiliated with University of Colorado Health Sciences Center Denver, Colorado Michael
More informationVISUAL INTEGRATION OF RESULTS FROM A LARGE DNA BIOBANK (BIOVU) USING SYNTHESIS-VIEW *
VISUAL INTEGRATION OF RESULTS FROM A LARGE DNA BIOBANK (BIOVU) USING SYNTHESIS-VIEW * SARAH PENDERGRASS Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt
More informationMedical Informatics in Healthcare Organizations: A Survey of Healthcare Information Managers
Medical Informatics in Healthcare Organizations: A Survey of Healthcare Information Managers Jeremiah H. Sable, MD, MHA, Joseph W. Hales, PhD, Kenneth D. Bopp, PhD Department of Health Management and Informatics
More informationHealth Care Delivery and Information Technology (HIT) Subcommittee : DRAFT Recommendations
President s Information Technology Advisory Committee (PITAC) Health Care Delivery and Information Technology (HIT) Subcommittee : DRAFT Recommendations April 13, 2004 President s Information Technology
More informationHow To Use An Electronic Medical Record
NIDA NATIONAL INSTITUTE ON DRUG ABUSE National ld Drug Abuse Treatment t Clinical Trials Network September 15, 2010 Betty Tai, Ph.D. Director, Center for the Clinical Trials Network NIDA/NIH/DHHS Development
More informationAppendix 6.2 Data Source Described in Detail Hospital Data Sets
Appendix 6.2 Data Source Described in Detail Hospital Data Sets Appendix 6.2 Data Source Described in Detail Hospital Data Sets Source or Site Hospital discharge data set Hospital admissions reporting
More information