UNIVERSITY OF MALTA FACULTY OF MEDICINE & SURGERY PHARMACY DEPARTMENT MATERIAL SAFETY DATA SHEET CETYL ALCOHOL. Table of Contents

Transcription

1 Table of Contents Page 1. Chemical Product 2 2. Composition and Information on Ingredients 2 3. Hazards Identification 2 4. First Aid Measures 3 5. Fire and Explosion Data 3 6. Accidental Release Measures 4 7. Handling and Storage 4 8. Exposure Controls/ Personal Protection 4 9. Physical and Chemical Properties Stability and Reactivity Data Toxicological Information Ecological Information Disposal Considerations References Appendices Revision History 7 Page 1 of 7

2 1. Chemical Product Product Name: Cetyl Alcohol Chemical name: Cetyl Alcohol Synonyms: 1-Hexadecanol; Adol; Cetaffine; Cetal; Cetylic alcohol; Cetylol; Ethal; Ethol; Hexadecan-1-ol; Hexadecyl alcohol; Lorol 24; Loxanol K; n-hexadecanol; n-hexadecyl alcohol; Palmityl alcohol Chemical Formula: C 16 H 34 O 2. Composition and Information on Ingredients Composition: Not applicable Toxicological Data on Ingredients: ORAL (LD50): Acute: 5000 mg/kg [Rat] mg/kg [Mouse]. DERMAL (LD50): Acute: 2600 mg/kg [Rabbit]. 3. Hazards Identification Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), eye contact (irritant), ingestion or inhalation. Potential Chronic Health Effects: Repeated or prolonged exposure is not known to aggravate medical condition. CARCINOGENIC EFFECTS: Not applicable MUTAGENIC EFFECTS: Not applicable TERATOGENIC EFFECTS: Not applicable DEVELOPMENTAL TOXICITY: Not applicable Page 2 of 7

3 4. First Aid Measures General measures: Skin contact: Wash with soap and water and cover the irritated skin with an emollient. Serious skin contact: Get medical attention if irritation develops or persists. Eye contact: Immediately remove any contact lenses and flush eyes with plenty of water for at least 15 minutes. Ingestion: Give one or two glasses of water to drink. Do not induce vomiting unless directed by medical personnel. Serious ingestion: Not applicable Inhalation: Loosen tight clothing such as a collar, tie, belt or waistband and remove victim to fresh air. If not breathing give artificial respiration and if breathing is difficult give oxygen. Serious inhalation: Not applicable 5. Fire and Explosion Data Flammability of the Product: Combustible solid Auto-Ignition Temperature: C Flash points: >93.3 C (PMCC) Flammable limits: Upper: 8% Lower: 1% Products of Combustion: Carbon oxides (CO, CO 2 ) Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of open flames and sparks, of heat. Page 3 of 7

4 Explosion Hazards in Presence of Various Substances: Not applicable Fire fighting media and Instructions: For a small fire use dry chemical powder. While for a large fire use water spray (not water jet), fog or foam. Special Remarks on Fire Hazards: Not applicable Special Remarks on Explosion Hazards: Not applicable 6. Accidental Release Measures NB: Wear appropriate protective equipment/clothing including gloves before removing any spills. Spills: Isolate spill area immediately and ventilate closed spaces. Use vacuum or broom sweeping to remove to disposal container and if damp, flush with water. Prevent entry into waterways, sewers, basements or confined areas. 7. Handling and Storage Precautions: Keep away from heat and sources of ignition. Ground all equipment containing material. Do not breathe dust. Keep away from incompatibles such as oxidizing agents, acids. Storage: Keep container tightly closed and stored in a cool, well-ventilated area. 8. Exposure Controls/Personal Protection Airborne Exposure Limits: Not applicable Engineering Controls: Not applicable Personal Protection: Wear gloves, safety glasses, lab coat and appropriate dust respirator when ventilation is inadequate. Page 4 of 7

5 9. Physical and Chemical Properties Physical state and appearance: White solid powder or flakes Odour: Odourless or faint citrus-like odour Taste: Bland and mild Molecular Weight: g ph (1% solution/water): 6-8 Boiling Point: 344 C (651.2 F) Melting Point: 49.3 C (120.7 F) Critical Temperature: C (910.1 F) Specific Gravity (Water = 1): 50 C Vapour Pressure (mmhg): Not applicable Vapour Density: 8.36 Volatility: Not applicable Odour Threshold: Not applicable Water/Oil Distribution Coefficient: Not applicable Ionicity (in Water): Not applicable Dispersion Properties: Water Solubility: 1.34x10-5 g/l Solubility: Easily soluble in diethyl ether, soluble in acetone and chloroform, slightly soluble in alcohol but insoluble in cold water. 10. Stability and Reactivity Data Stability: Stable Corrosivity: Non-corrosive in presence of glass. Instability temperature: Not applicable Conditions of Instability: Excess heat and incompatible materials. Incompatibles: Reactive with strong oxidizing agents and strong mineral acids. Polymerization: Not applicable Page 5 of 7

6 11. Toxicological Information Toxicity to animals: ORAL (LD50): Acute: 5000 mg/kg [Rat] mgkg -1 [Mouse]. INHALATION (LD50): Acute: 2220mg/m 3 /6H [Rat]. DERMAL (LD50): Acute: 2600 mg/kg [Rabbit] mgkg -1 [Guinea Pig]. Effects on humans: Acute potential health effects: Mild to moderate skin irritation, mild eye irritation and may also cause respiratory tract infection. When ingested may cause hypermotility and diarrhoea, and may affect the cardiovascular system, respiration and behaviour/central nervous system (tremor, ataxia). Chronic potential health effects: MUTAGENIC EFFECTS: Not applicable TERATOGENIC EFFECTS: Not applicable DEVELOPMENTAL TOXICITY: Not applicable Other information: Not applicable 12. Ecological Information Ecotoxicity: Not available 13. Disposal Considerations Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an approved incinerator or disposed in an approved waste facility. Dispose in the container marked NON-HAZARDOUS WASTE. 14. References - Sciencelab.com. Material Safety Data Sheet; Cetyl Alcohol. [Online] [cited 2013 Oct 10]. Available from: URL: - CLP Chemicals. Cetyl Alcohol; Material Safety Data Sheet. [Online]. [cited 2013 Oct Page 6 of 7

7 10]. Available from: URL: icals.pdf - Making Cosmetics. Cetyl Alcohol; Material Safety Data Sheet. [Online] [cited 2013 Oct 10]. Available from: URL: - Flinn Scientific Inc. Material Safety Data Sheet. [Online] [cited 2013 Oct 10]. Available from: URL: Appendices Not applicable 16. Revision History Version Number Amendments/ Reasons for change 01 Initial Release Page 7 of 7