CURRICULUM VITAE. Yong-Cheol Park, Ph.D.

Transcription

1 CURRICULUM VITAE Yong-Cheol Park, Ph.D. Postdoctoral Research Associate Department of Biochemistry and Cell Biology, Rice University, Houston, TX , U.S.A. Tel) , Fax) , ) EDUCATION August 1999 ~ August 2003 March 1994 ~ February 1996 March 1990 ~ February 1994 Ph.D. Interdisciplinary Program for Biochemical Engineering & Biotechnology, Seoul National University (Dissertation: Analysis and Optimization of D-Ribose Production by Metabolically Engineered Bacillus subtilis) M.S. Interdisciplinary Program for Biochemical Engineering & Biotechnology, Seoul National University (Thesis: Overexpression of Cyclodextrin Glucanotransferase from Bacillus macerans in Recombinant Escherichia coli) B.S. Department of Food Science & Technology, Seoul National University PROFESSIONAL EXPERIENCE July 2004 ~ Present Postdoctoral research associate, Department of Biochemistry and Cell Biology, Rice University, Houston, Texas, U.S.A. July 2004 ~ June 2005 Awardee, Post-doctoral overseas fellowship of Korea Science and Engineering Foundation September 2003 ~ July 2004 Postdoctoral researcher, Brain Korea 21, Department of Food Science and Technology, Seoul National University, Korea July 2001 ~ September 2001 Visiting researcher, School of Chemical Engineering, Cornell University, U.S.A. August 1999 ~ August 2003 Researcher, Center for Agricultural Biomaterials, Korea August 1997 ~ July 1999 Researcher, Research and Development Center, Tong Yang Confectionary Co., Korea July 1996 ~ July 1997 Researcher, Jinro Central Research Institute, Jinro Co., Korea

2 TEACHING EXPERIENCE March 2004 ~ June 2004 March 2004 ~ June 2004 Fall Semester 1994 Lecturer, Physical chemistry, Seoul National University Lecturer, Food Biochemistry, Korea University Teaching assistant (Advanced Mathematic Engineering) Department of Food Science and Technology, Seoul National University, Korea PUBLICATIONS 22. Y. C. Park, J. H. Choi, G. N. Bennett and J. H. Seo Characterization of D-ribose biosynthesis in Bacillus subtilis JY200 deficient in transketolase gene. Journal of Biotechnology. Submitted. (I/F:2.543) 21. W. H. Lee, Y. C. Park, D. H. Lee, K. M. Park and J. H. Seo Simultaneous biocatalyst production and Baeyer-Villiger Oxidation for bioconversion of cyclohexanone by recombinant Escherichia coli expressing cyclohexanone monooxygenase. Applied Biochemistry and Biotechnology. 123 (1-3), (I/F:0.890) 20. S. G. Kim, D. H. Kweon, D. H. Lee, Y. C. Park and J.H. Seo Coexpression of folding accessory proteins for production of active cyclodextrin glycosyltransferase of Bacillus macerans in recombinant Escherichia coli. Protein Expression and Purification. 41, (I/F:1.470) 19. Y. C. Park, S. J. Kim, J. H. Choi, W. H. Lee, K. M. Park, M. Kawamukai, Y. W. Ryu and J. H. Seo Batch and fed-batch production of coenzyme Q 10 in recombinant Escherichia coli containing decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. Applied Microbiology and Biotechnology. 67, (I/F:2.034) 18. Y. C. Park, D. Y. Lee, D. H. Lee, H. J. Kim, Y. W. Ryu and J. H. Seo Proteomics and physiology of erythritol producing strains. Journal of Chromatography B 815(1-2), (I/F:2.085) 17. Y. C. Park, S. K. Kim, K. M. Park, K. H. Lee and J. H. Seo Fed-batch production of D-ribose from sugar mixtures by transketolase deficient Bacillus subtilis SPK1. Applied Microbiology and Biotechnology 66(3), (I/F:2.034) 16. S. M. Bae, Y. C. Park, T. H. Lee, D. H. Kweon, J. H. Choi, S. K. Kim, Y. W. Ryu and J. H. Seo Production of xylitol by recombinant Saccharomyces cerevisiae containing xylose reductase gene in repeated fed-batch and cell-recycle fermentation. Enzyme and Microbial Technology 35(6-7), (I/F:1.501) 15. H. J. Kim, D. Y. Lee, D. H. Lee, Y. C. Park, D. H. Kweon, Y. W. Ryu and J. H. Seo Strategic proteome analysis of Candida magnoliae with an unsequenced genome. Proteomics 4(11), (I/F:5.766) 14. Y. C. Park and J. H. Seo Optimization of culture conditions for D-ribose production by transketolase deficient Bacillus subtilis JY1. Journal of Microbiology and Biotechnology

3 14(4), (I/F:1.364) 13. D. Y. Lee, Y. C. Park, H. J. Kim, Y. W. Ryu and J. H. Seo Proteomic analysis of Candida magnoliae strains by two dimensional electrophoresis and mass spectrometry. Proteomics 3(12), (I/F:5.766) 12. Y. S. Jeun, M. D. Kim, Y. C. Park, T. H. Lee, M. S. Yoo, Y. W. Ryu and J. H. Seo Expression of Azotobacter vinelandii soluble transhydrogenase perturbs xylose reductasemediated conversion of xylose to xylitol by recombinant Saccharomyces cerevisiae. Journal of Molecular Catalysis B: Enzymatic 26(3-6), (I/F: 1.475) 11. T. H. Lee, M. D. Kim, Y. C. Park, S. M. Bae, Y. W. Ryu and J. H. Seo Effects of xylulokinase activity on ethanol production from D-xylulose by recombinant Saccharomyces cerevisiae. Journal of Applied Microbiology 95(4), (I/F:1.743) 10. Y. C. Park, D. H. Kweon, D. H. Lee and J. H. Seo Improved technologies to produce heterologous proteins in recombinant Escherichia coli. Korean Journal of Biotechnology and Bioengineering 16(1), H. H. Jin, N. S. Han, D. H. Kweon, Y. C. Park and J. H. Seo Effects of environmental factors on in vivo folding of Bacillus macerans cyclodextrin glycosyltransferase in recombinant Escherichia coli. Journal of Microbiology and Biotechnology 11(1), (I/F: 1.364) 8. C. I. Kim, M. D. Kim, Y. C. Park, N. S., Han and J. H. Seo Refolding of Bacillus macerans cyclodextrin glucanotransferase expressed as inclusion bodies in recombinant Escherichia coli. Journal of Microbiology and Biotechnology 10(5), (I/F: 1.364) 7. S. W. Jung, S. S. Park, Y. C. Park, T. K. Oh and J. H. Seo Analysis of production of thermostable alkaline protease using Thermoactinomyces sp. E79. Korean Journal of Applied Microbiology and Biotechnology 28(3), K. A. Kim, B. S. Noh, J. K. Lee, S. Y. Kim, Y. C. Park and D. K. Oh Optimization of culture conditions for erythritol production by Torula sp.. Journal of Microbiology and Biotechnology 10(1), (I/F: 1.364) 5. H. J. Roh, P. Kim, Y. C. Park and J. H. Choi Bioconversion of D-galactose into D- tagatose by expression of L-arabinose isomerase. Biotechnology and Applied Biochemistry 31(1), 1-4. (I/F:1.000) 4. S. H. Yoon, Y. C. Park, S. Y. Kim, B. S. Noh and D. K. Oh Growth inhibition of Aspergillus repens in a composite chocolate product by an antifungal agent. Food Science and Biotechnology 8(1), (I/F: 1.364) 3. J. H. Koo, S. Y. Kim, Y. C. Park, N. S. Han and J. H. Seo Invertase production by fed-batch fermentations of recombinant Saccharomyces cerevisiae. Journal of Microbiology and Biotechnology 8(3),

4 2. Y. C. Park, C. S. Kim, C. I. Kim, K. H. Choi and J. H. Seo Fed-batch fermentation of recombinant Escherichia coli to produce Bacillus macerans CGTase. Journal of Microbiology and Biotechnology 7(5), Y. C. Park, C. S. Kim, N. S. Han and J. H. Seo Expression of cyclodextrin glucanotransferase from Bacillus macerans in recombinant Escherichia coli. Foods and Biotechnology 4(4), PATENTS 1. Seo, J. H., Y. C. Park, S. Y. Kim, J. K. Lee, S. J. Ha, and S. K. Kim A biological method for producing D-ribose from D-xylose using a Bacillus subtilis mutant. Korea Patent. Filed no Roh, H. J., Y. C. Park, S.S. Kim, N. B. Soo and J. H. Choi Co-crystal sugars with sweet inhibitors and production methods of co-crystallization. Korea Patent. No Moon, Y. H., J. N. Choi, Y. Y. Chae, J. H. Lee, Y. C. Park and K. H. Choi Cloning vector using anti-viral protein (PIP) gene of Phytolacca insularis. Korea Patent. Filed no BOOK Seo, J. H., W. J. Lee, M. D. Kim, C. S. Kim and Y. C. Park Overproduction of bacterial amylases in recombinant Escherichia coli systems, pp In K. H. Park, J. H. Robyt and Y. D. Choi (ed.), Enzymes for carbohydrate engineering, Progress in Biotechnology, vol. 12. Elsevier, New York, U.S.A. PRESENTATION (international) Seo. J. H., K. C. Han, E. S. Koh, J. B. Park, Y. C. Park, S. W. Yang, Y. W. Ryu Characterization of physiological properties of an osmophilic mutant Candida magnoliae to produce erythritol. BIOT 303, Proceeding of 219 th ACS National Meeting, American Chemical Society, U.S.A. EXPERIMENTAL SKILLS Instrument analysis Two-Dimensional Electrophoresis : Bacillus subtilis and Candida magnoliae proteome analyses HPLC : analyses of sugar, sugar alcohol, ethanol, organic acids GC/GC-MS : identification and quantification of flavors and lipids ELISA, TLC Skills

5 DNA manipulation for E. coli, B. subtilis, S. cerevisiae Polymerase Chain Reaction Microbial culture using several techniques such as fed-batch, continuous processes and high-cell density Metabolic engineering, Metabolic control analysis Mathematical modeling and optimization REFERENCES Prof. Jin-Ho Seo, Ph. D. Department of Food Science and Technology, Seoul National University, Seoul , Korea Tel) ) Prof. Kelvin H. Lee, Ph. D. School of Chemical & Biomolecular Eng., Cornell University, Ithaca, NY 14853, U.S.A. Tel) ) Prof. George N. Bennett, Ph. D. Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, U.S.A. Tel) ) rice.edu Prof. Nam Soo Han, Ph. D. Department of Food Science and Technology, Choongbuk National University, Chungju , Korea Tel) )