ALLERGY/MOLD Gene & Variation rsid # Risk Allele Your Alleles and Results HLA rs C TT -/- HLA rs T GG -/-

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1 DETOX CYP1A1*2C A4889G rs C TT -/- CYP1A1*4 C2453A rs T GG -/- CYP1A2 C164A rs C AA -/- CYP1B1 L432V rs C CC +/+ CYP1B1 N453S rs C TT -/- CYP1B1 R48G rs10012 C no call CYP2A6*2 A1799T rs T AA -/- CYP2C19*17 rs T CT +/- CYP2C9*2 C430T rs T CC -/- CYP2C9*3 A1075C rs C AA -/- CYP2D6 S486T rs C CC +/+ CYP2D6 T100C rs A GG -/- CYP2D6 T2850C rs16947 A GG -/- CYP2E1*1B G9896C rs G CG +/- CYP2E1*4 A4768G rs A GG -/- CYP3A4*1B rs C TT -/- CYP3A4*3 M445T rs G AA -/- GSTM1 rs T CC -/- GSTM1 rs A GG -/- GSTM1 rs G AA -/- GSTM1 rs A TT -/- GSTM1 rs T CC -/- GSTM1 rs A TT -/- GSTM1 rs G AA -/- GSTP I105V rs1695 G GG +/+ GSTP1 A114V rs T CC -/- NAT1 A560G(?) (R187Q) rs A GG -/- NAT2 A803G (K268R) rs1208 G AA -/- DETOX NAT2 C190T (R64W) rs T CC -/- NAT2 G590A (R197Q) rs A AG +/- NAT2 G857A (G286E) rs A GG -/- NAT2 T341C (I114T) rs C TT -/- SOD2 rs A CC -/-

2 SOD2 A16V rs4880 G AG +/- TONGUE TIE / CLEFT PALATE CTH S4031I rs T GG -/- RARA rs G AG +/- RARA rs T CT +/- TBX22 rs A TT -/- TBX22 rs T AA -/- ALLERGY/MOLD HLA rs C TT -/- HLA rs T GG -/- IgE C3 rs G GT +/- FCER1A rs C CC +/+ FCER1A rs A AA +/+ IL-13 C1112T rs T CC -/- DARC rs C TT -/- IL13 rs A AG +/- CD14 rs C CT +/- SOCS-1-820G>T rs A CC -/- C3 rs G GT +/- FCER1A / OR10J2P rs A AA +/+ FCER1A rs C CC +/+ RAD50 rs G AA -/- RAD50 rs T CC -/- IgG FCGR2A rs A AG +/- GSTM3 V224I rs7483 T CC -/-

3 TNFRSF13B rs G AG +/- IgA TRAF1 rs G AA -/- IRF5 rs A GG -/- IGF1R rs A AG +/- IFIH1 (HLA) rs C CT +/- HLA rs G AG +/- HLA-DQA2 rs A AG +/- CFH rs A GG -/- MTC03P1 rs C CT +/- PSMB8 / TAP1 / TAP2 rs A GG -/- HLA-DPB2 / COL11A2P rs A GG -/- CLOTTING FACTORS CYP4V2 rs C AA -/- GP6 rs G AG +/- ITGB3 rs5918 C CT +/- KNG I598T rs T CC -/- NR1I2 rs C AA -/- SERPINC1 rs T CC -/- HRG rs9898 T TT +/+ F12 rs A GG -/- F11 rs T CT +/- F11 rs T CC -/- F rs G AG +/- F7 rs6046 A GG -/- F2 (Prothrombin 20210A) I / rs A GG -/- F rs A GG -/- F5 (Factor V Leiden) rs6025 T CC -/- F9 G580A rs6048 G AA -/- More info: METHYLATION

4 ACAT1-02 rs A GG -/- ACE Del16 rs (rs4343) D (G) AG +/- AGT M235T/C4072T rs699 G AG +/- AHCY-01 rs C TT -/- AHCY-02 rs G AA -/- AHCY-19 rs C TT -/- BCMO1 rs C CC +/+ BCMO1 R267S rs T TT +/+ BCMO1 A379V rs T CT +/- BHMT-02 rs T CT +/- BHMT-04 rs C AC +/- BHMT-08 rs T TT +/+ CBS A13637G rs T CT +/- CBS A360A rs A AG +/- CBS C19150T rs A GG -/- CBS C699T rs A GG -/- CBS I278T rs G AA -/- CBS N212N rs A GG -/- COMT rs6269 A AA +/+ COMT -61 P199P rs A GG -/- COMT H62H rs4633 T CT +/- COMT V158M rs4680 A AG +/- DHFR rs C TT -/- FOLR1 rs A GG -/- FOLR2 rs G AG +/- FOLR3 rs G AA -/- FOLR3 rs A CC -/- FUT2 rs A AG +/- FUT2 rs A AG +/- FUT2 rs A AG +/- METHYLATION G6PD rs C TT -/- GAD1 rs A GG -/- GAD1 rs C TT -/- GAD1 rs C TT -/- GAD1 rs C CG +/-

5 GAD1 rs C CT +/- GAD1 rs A GG -/- GAD1 rs A AC +/- GAD1 rs T GT +/- GAD1 rs T CT +/- GAD1 rs A GG -/- GAD1 rs T CT +/- GAD1 rs T CT +/- GAD1 rs G AG +/- GAD2 rs T GG -/- GIF (TCN3) rs A GG -/- MAO A R297R rs6323 T GT +/- MAO B rs A CC -/- MTHFD1 C105T rs T TT +/+ MTHFD1 G1958A rs A AG +/- MTHFD1L rs A GG -/- MTHFD1L rs C TT -/- MTHFD1L rs A GG -/- MTHFD1L rs A AG +/- MTHFR 03 P39P rs A AG +/- MTHFR A1298C rs G GG +/+ MTHFR A1572G rs G AG +/- MTHFR C677T rs A GG -/- MTHFR G1793A (R594Q) rs T CT +/- MTR A2756G rs G AG +/- MTRR A66G rs G GG +/+ METHYLATION MTRR H595Y rs10380 T CC -/- MTRR K350A rs G AA -/- MTRR R415T rs T CC -/- MTRR-11 A664A rs A GG -/- NOS1 rs T CC -/- NOS2 rs A GG -/- NOS2 rs T GT +/- NOS2 rs A AG +/- NOS3 rs A TT -/- NOS3 rs G AA -/-

6 NOS3 rs A AC +/- NOS3 G10T rs7830 T GG -/- NOS3 T786C rs C TT -/- PEMT rs T GG -/- PEMT rs T AT +/- PEMT rs7946 C CT +/- SHMT1 C1420T rs A GG -/- SHMT1 rs C CT +/- SHMT2 rs T GG -/- SHMT2 rs A AA +/+ SLC19A1 rs C CC +/+ SLC19A1 rs A GG -/- SOD2 rs T CT +/- TCN1 rs G AA -/- TCN2 C766G rs G CC -/- TYMS rs T CT +/- VDR Bsm rs T CC -/- VDR Taq rs G AA -/- CELIAC DISEASE/GLUTEN INTOLERANCE HLA rs G AG +/- HLA DQA1 rs T CC -/- THYROID FOXE1 rs A AG +/- FOXE1 rs C AA -/- FOXE1 rs A AA +/+ OTHER IMMUNE FACTORS 4q27 Region rs T GG -/- ADD1 G460W rs4961 T GT +/- APOE rs C TT -/- ATG16L1 rs T TT +/+

7 CTLA4 (celiac's/hashimotos) rs G AA -/- HLA-DRB1 rs G AA -/- IL5 rs G AG +/- IL-13 rs20541 A AG +/- IL4R Q576R rs G AG +/- MeFV A744S i A CC -/- MeFV E148Q rs G CC -/- MeFV F479L i C GG -/- MeFV K695R i C TT -/- MeFV M680I rs G CC -/- MeFV M694I rs T CC -/- MeFV M694V i C TT -/- MeFV P369S rs A GG -/- MeFV R761H i T CC -/- STAT4 rs G GG +/+ TNF -308 rs A AG +/- TNF -238 rs A GG -/- TYR (MeFV) V726A rs A GG -/- Prepared by: This report is intended to translate your results into an easier to understand form. It is not intended to diagnose or treat. For diagnosis or treatment, please present this to your doctor (or find a doctor on under "Find a Practitioner"). Additionally, genetic mutations are flags that something *could* be wrong and not a guarantee that you are having all or any of the associated issues. Other factors like environment, ethnic background, diet, age, personal history, etc all have a factor in whether a mutation starts to present itself or not and when. No two people are alike, and there is no "one size fits all" cure for any of this. No Result From 23andme = NO CALL "Normal" = -/- Heterozygous = +/- Homozygous = +/+ Males may only see one allele listed for some SNPs rather then 2. This happens when the SNP is located on the X chromosome.

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