Sune Høgild Keller, PhD Computer Scientist in Molecular Imaging

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1 , PhD Computer Scientist in Molecular Imaging Department of Clinical Physiology, Nuclear Medicine & PET Rigshospitalet, Copenhagen University Hospital Blegdamsvej 9, DK-2100 Copenhagen Phone : (+45) sune@pet.rh.dk Education PhD, entitled Video Upscaling Using Variational Methods. Full scholarship. University of Copenhagen, Faculty of Science, The Image Group. MSc IT, Multimedia Technology, IT University of Copenhagen. BSc in Chemistry, University of Copenhagen, with a 90 ECTS minor in Science of Film and Media. Employment Computer scientist and mathematician at the Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet. R&D on the HRRT and PET/MR, and physics responsible on clinical research projects. Daily maintenance, support and development of the HRRT, PET/CT and PET/MR scanners. Management of image workflows (DICOM, PACS, Mirada, Syngo.Via, PMOD etc.) in the department Post doc, Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet. R&D on the Siemens simultaneous whole-body PET/MR and physics responsible on clinical research projects. Daily maintenance, support and development of PET/CT scanners and PET/CT image workflows. Post doc, Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet. Siemens funded R&D on the methods and software of the High Resolution Research Tomograph (HRRT) on behalf of the HRRT Users Community. Physics support of neurological research. Post doc, The Image Group, Faculty of Science, University of Copenhagen. 1

2 2007 Scientific Assistant, The Image Group, Faculty of Science, University of Copenhagen. Grants 2012 Savværksejer Jeppe Juhl og Hustru Ovita Juhls Mindelegat (200,000 DKK). Publications 2013 Sune H. Keller, Claus Svarer and Merence Sibomana. Attenuation correction for the HRRT PET-scanner using transmission scatter correction and total variation regularization, IEEE Transactions on Medical Imaging, DOI /TMI , E-pub ahead of print, Claes Nøhr Ladefoged, Flemming Littrup Andersen,, Johan Löfgren, Adam Espe Hansen, Søren Holm, Liselotte Højgaard and Thomas Beyer. PET/MR imaging of the pelvis in the presence of endoprostheses: reducing image artifacts and increasing accuracy through inpainting, Eur J Nucl Med Mol Imaging, DOI /s , Online 8 January Sune H. Keller, Merence Sibomana, Oline V. Olesen, Claus Svarer, Søren Holm, Flemming L. Andersen, and Liselotte Højgaard. Methods for motion correction evaluation using FDG human brain scans on a high resolution PET scanner, Journal of Nuclear Medicine, Vol. 53, No. 3, pp , Sune H. Keller, Søren Holm, Adam E. Hansen, Bernhard Sattler, Flemming Andersen, Thomas L. Klausen, Liselotte Højgaard, Andreas Kjær and Thomas Beyer. Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI, Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA), vol. 26, issue 1, pp , Andreas Kjær, Annika Loft, Ian Law, Anne Kiil Berthelsen, Lise Borgwardt, Johan Löfgren, Camilla B. Johnbeck, Adam E. Hansen, Sune Keller, Søren Holm and Liselotte Højgaard. PET/MRI in cancer patients: first experiences and vision from Copenhagen, Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA), Online 25 December Thomas Levin Klausen,, Oline Vinter Olesen, Marianne Aznar and Flemming L. Andersen. Innovations in PET/CT, The Quarterly Journal of Nuclear Medicine and Molecular Imaging 2012, 56(3):268-79, Sune H. Keller, Adam E. Hansen, Thomas Beyer, Flemming L. Andersen, Thomas L. Klausen, Johan Löfgren, Søren Holm. Evaluation of PET Image Quality and Distortions in Simultaneous Clinical PET/MR, IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, Merence Sibomana, Sune H. Keller, Simon Stute, Claude Comtat. Benefits of 3D Scatter Correction for the HRRT - a Large Axial FOV PET Scanner, IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, Adam Espe Hansen,, Johan Löfgren, and Søren Holm. Kombineret PET/MR skanner på Rigshospitalet: første erfaringer, Medicinsk Teknologi & Informatik, Vol. 9, No. 3, pp. 9-10,

3 2011, François Lauze and Mads Nielsen. Video Super-Resolution using Simultaneous Motion and Intensity Calculations, IEEE Transactions on Image Processing, Vol. 20, Issue 7, pp , June Karine Madsen, Mette T. Haahr, Lisbeth Marner, Sune H. Keller, William F. Baaré, Claus Svarer, Steen G. Hasselbalch, Gitte M. Knudsen. Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB PET study, Journal of Cerebral Blood Flow & Metabolism, 2011;31(6): Oline V. Olesen, Rasmus R. Paulsen, Rasmus R. Jensen, Sune H. Keller, Merence Sibomana, Liselotte Højgaard, Bjarne Roed, and Rasmus Larsen. 3D Surface Realignment Tracking for Medical Imaging: A Phantom Study with PET Motion Correction, In Proceedings of the MICCAI workshop on Mesh Processing in Medical Image Analysis (MeshMed), Ed. Yongjie Zhang, Springer, Olesen V. Olesen, Rasmus R. Paulsen, Sune H. Keller, Liselotte Højgaard, Bjarne Roed, and Rasmus Larsen. Comparison of external motion tracking systems for PET list-mode reconstruction, In IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, M. L. Lassen, F. Andersen, J. M. Grüner, S. Keller, I. Law. Non-invasive quantification of blood flow in the brain using 15O-labelled water in the HRRT scanner, EANM , François Lauze and Mads Nielsen. Temporal Super Resolution Using Variational Methods, In Marta Mrak, Mislav Grgic and Murat Kunt, editors, High-Quality Visual Experience: Creation, Processing and Interactivity of High-Resolution and High-Dimensional Video Signals, Springer, 2010, ISBN: Oline Vinter Olesen, Claus Svarer, Merence Sibomana,, Søren Holm, Jørgen A. Jensen, Flemming Andersen and Liselotte Højgaard. A Movable Phantom Design for Quantitative Evaluation of Motion Correction Studies on High Resolution PET Scanners, In IEEE Trans. on Nuclear Science, Vol. 57, Issue 3. pp , June Oline V. Olesen, Sune H. Keller, Merence Sibomana, Rasmus Larsen, Bjarne Roed, and Liselotte Højgaard. Automatic Thresholding for Frame-Repositioning Using External Tracking in PET Brain Imaging, In 2010 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, J. M. Anton-Rodriguez, M. Sibomana, M. D. Walker, M. C. Huisman, J. C. Matthews, M. Feldmann, S. H. Keller, M.-C. Asselin. Investigation of Motion Induced Errors in Scatter Correction for the HRRT Brain Scanner, In 2010 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, M. C. Huisman, J. E. M. Mourik, F. H. P. van Velden, M. Sibomana, S. H. Keller, S. Wang, J. Anton, D. van Assema, F. E. A. M. Froklage, N. J. Hoetjes, R. W. Kloet, B. N. M. van Berckel, R. C. Schuit, M. Lubberink, R. Boellaard, A. A. Lammertsma. Quantitative Accuracy of the HRRT in an Interscanner Study with the HR+ and (R)-[11C]verapamil, 2010 IEEE Nuclear Science Symposium (MIC), IEEE, Oline Olesen, Flemming Andersen, Søren Holm, Jørgen Jensen, Sune Keller, Merence Sibomana, Claus Svarer and Liselotte Højgaard. A new tool fixation for external 3D head tracking using the Polaris Vicra 3

4 system with the HRRT PET scanner, In Society of Nuclear Medicine Annual Meeting Abstracts, SNM, Claus Svarer, Lisbeth Marner, Karine Madsen, Sune Keller, Mette Haahr, Merence Sibomana and Gitte Knudsen. HRRT and Advance scanner comparison using a steady-state scan approach, In Society of Nuclear Medicine Annual Meeting Abstracts, SNM, Merence Sibomana,, Claus Svarer, Oline Vinter Olesen, Flemming Andersen, Søren Holm and Liselotte Højgaard. New Attenuation Correction for the HRRT Using Transmission Scatter Correction and Total Variation Regularization, In 2009 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, Oline Vinter Olesen, Merence Sibomana,, Flemming Andersen, Jørgen Jensen Søren Holm, Claus Svarer and Liselotte Højgaard. Spatial Resolution of the HRRT PET Scanner Using 3D-OSEM PSF Reconstruction, In 2009 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, Merence Sibomana,, Søren Holm, Peter M. Bloomfield, Stephan Blinder, Søren Baarsgaard Hansen and Christian Michel. Component-Based Normalization for the HRRT Sinogram- Mode Reconstruction, In 2009 IEEE Nuclear Science Symposium Conference Record (MIC), IEEE, , François Lauze and Mads Nielsen. Deinterlacing Using Variational Methods, In IEEE Transactions on Image Processing, volume 17, number 11, pages , , François Lauze and Mads Nielsen. Motion Compensated Video Super Resolution, In F. Sgallari, A. Murli and N. Paragios, editors, Scale Space and Variational Methods in Computer Vision, SSVM 2007 Proceedings, LNCS 4485, pages , Berlin, Springer, PhD Thesis:, Video Upscaling Using Variational Methods, Faculty of Science, University of Copen-hagen, 2007, available online: Sune Keller, François Lauze and Mads Nielsen. Variational Motion Compensated Deinterlacing, In. 3rd Workshop on Statistical Methods in Multi-Image and Video Processing (SMVP), 9th ECCV Workshop Proceedings, 2006., François Lauze and Mads Nielsen. Variational Deinterlacing, IT University Technical Report Series, TR , ISBN , Sune Keller, Kim S. Pedersen and François Lauze. Detecting Interlaced or Progressive Source of Video, In. Proceedings of the 2005 IEEE Seventh Workshop on Multimedia Signal Processing, Sune Keller, François Lauze and Mads Nielsen. A Total Variation Motion Adaptive Deinterlacing Scheme, In. R. Kimmel, N. Sochen and J. Weickert, editors, Scale Space and PDE Methods in Computer Vision, 5th International Conference, Scale-Space 2005, Proceedings, LNCS 3459, pages , Springer,

5 Patent Applications 30/09/2004: US 60/614,420, A Method of Adding Information to a Frame or a Field in a Video Sequence, Inventors: Sune Keller, François Lauze and Mads Nielsen. 30/09/2005: PCT WO-A-2006/ (PCT/EP2005/054957), A Method of Adding Information to a Frame or a Field in a Video Sequence, Inventors: François Lauze, Sune Keller and Mads Nielsen. 30/09/2005: US 11/239697, A Method of Adding Information to a Frame or a Field in a Video Sequence, Inventors: François Lauze, Sune Keller and Mads Nielsen. Teaching Various teaching on PET with a focus on image reconstruction to an audience ranging from 1 st year students to professors. Supervision of projects (MSc, BSc, smaller) in computer science (imaging) and engineering (medicine & technology), co-supervision of PhD projects in nuclear imaging (engineering and medicine). Teacher, lectures and lab/exercises classes in Multimedia Programming (human vision, programming, image and sound processing, computer architecture, networking etc.) ITU. Project supervision, smaller student projects and MSc theses in programming, games, computer graphics etc. at ITU. Teaching assistant, lab/exercises in Image Analysis, ITU. Teaching assistant, lab/exercises in Signal Processing, ITU. Boards and Committees Member of the PhD study board at ITU. Member of the board of owners in my apartment building. Project manager: Common Internet/TV/phone solution in the building. Member of the event committee at my student home. The last two years serving as chairman and webmaster. 5

6 Programming Skills Expert: Java, C++, C, Matlab. Intermediate: Perl, Python, HTML. Clincal Imaging Environments HRRT, Pmod, Osirix, Vinci (HRRT), Syngo MMWP, Syngo.Via, DICOM, PACS, Merida, Mirada, Siemens Truepoint + mct PET/CT scanners, Siemens mmr. Language Skills Danish English German Swedish & Norwegian Fluent, my native language. Fluent. A-level in high school, close to fluent. Fluent except for writing. Self-taught. Recreational Interests Floorball, photography, canoeing, Swedish wildlife, culture and society, literature, music, films, technology and lots more. 6

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