1 CONTENTS PAGE OF THE ISSUE DECEMBER OF 2011 EQUINE B. Vincze, F. Baska, O. Szenci: Congenital skin diseases of newborn foals. Literature review / 707 PORCINE T. Süveges, Zs. Kléh: Experiences on Talfan-disease in piglets / 713 RABBIT Z. Német, O. Szenci, I. Biksi: Staphylococcosis in domestic rabbit. Literature review and domestic experiences / 720 SMALL ANIMALS P. Csébi, L. Balogh, Cs. Jakab, T. Ipolyi, P. Molnár, A. Arany Tóth: Intracranial meningeoma in a cat. Clinicopathologic case report / 727 K. Matiz, I. Turcsányi Kecskemétiné, Á. Bacsadi, E. Bajmócy, S. Kecskeméti: Mycoplasma infection of dogs. Domestic experiences / 735 LABORATORY ANIMALS A. Sebestény, S. Gy. Fekete: Vitamin K deficiency in rederived SPF rodents. Case reports / 742 WILD ANIMALS
2 M. Z. Vidovszky, S. Boldogh: Detection of adenoviruses in the Northern Hungarian bat fauna / 747 S. Sikó Barabási, V. Cozma: Occurrence of Echinococcus multilocularis and alveolar echinococcosis in Romania / 754 LETTER TO THE EDITOR Observations on the neoplastic diseases of geese (I. Csapó) / 763 JUBILEE Professor József Márkus ( ) was born 100 years ago (L. Fésüs) / 764 IN MEMORIAM Mónika Kovácsné Domokos (F. Kutas) / 765 EVENT Szent-Iványi Binder day and Rudnai Kemenes day (S. Tuboly) / th Derzsy-days (Sárvár, 2 3 June 2011) (Gy. Nagy) / 766 B. Vincze F. Baska O. Szenci: CONGENITAL SKIN DISEASES OF NEWBORN FOALS. LITERATURE REVIEW Skin lesions are relatively common in newborn and young foals and they can be congenital or acquired. The most common congenital skin
3 diseases of newborn foals are discussed. Epitheliogenesis imperfecta, epidermolysis bullosa, generalized primary seborrhea, curly coat syndrome, LWO syndrome, white foal syndrome, lavender foal syndrome, Fell pony immunocompromise syndrome, congenital equine cutaneous mastocytosis, congenital vascular hamartoma and congenital papillomatosis are primary diseases. Secondary disorders are: congenital hypothyroidism and ulcerative dermatitis, thrombocytopenia and neutropenia syndrome. These conditions are rarely seen, but most of them are severe. Some of them are hereditary problems. T. Süveges Zs. Kléh: EXPERIENCES ON TALFAN-DISEASE IN PIGLETS The authors diagnosed the disease on a pig holding keeping 500 sows. The disease causing neurological and locomotor disorders occurred in 1 6 weeks old piglet. Younger and older animals kept with them were not affected. In the brain and spinal cord of animals that died or were bled to death for diagnostic purpose, at the sites typical to enterovirus encephalomyelitis, but much milder changes were detected (lymphocytic, histiocytic polioencephalomyelitis and leptomeningitis characterised by mild gliaproliferation). Diseases important from differential diagnostic point of view (streptococcosis, Glässer-disease, etc.) were excluded by laboratory methods. The disease causing only mild mortality increased death rate by 4% in suckling piglets and by 2% in rearing piglets.
4 Z. Német O. Szenci I. Biksi: STAPHYLOCOCCOSIS IN DOMESTIC RABBIT. LITERATURE REVIEW AND DOMESTIC EXPERIENCES The authors review old and novel facts and information on various syndromes caused by Staphylococcus aureus infection in domestic rabbits. Predisposing factors of these conditions are assessed in details. Clinical signs and lesions are described according to the affected age group (sucklings, breeders). The means of detection of the pathogen is discussed along with current options for differentiating high and low virulence strains. The determination of virulence type through biochemical tests, phage-typing, genotyping or with multiplex polymerase chain reaction (PCR) has important implications in treatment options and disease prognosis. The authors emphasize public health significance of Staphylococcus aureus strains, as they describe MRSA strains and the methods of detection. P. Csébi L. Balogh Cs. Jakab T. Ipolyi P. Molnár A. Arany Tóth: INTRACRANIAL MENINGEOMA IN A CAT The authors diagnosed by CT examination a homogenous mass in the left temporal lobe in an 11.5 year old female European shorthair cat showing left sided forebrain neurological signs. Based on the diagnostic
5 imaging result craniotomy was performed and the majority of the mass was removed. Radiotherapy combined with electromagnetic hyperthermia treatment was used because of the incomplete resection. The remaining tumour tissue was heated to 42 o C by electromagnetic hyperthermia and then radiotherapy with 3 Gray radiation dosage was performed. The treatment was repeated on every second day, altogether 6 times. The CT scanning was repeated 5 month later and no new tumour tissue was diagnosed. The tumour mass was transitional cell meningioma, based on the immunohistochemistry. K. Matiz I. Turcsányi Kecskemétiné Á. Bacsadi E. Bajmócy S. Kecskeméti: MYCOPLASMA INFECTION OF DOGS The authors give a short overview of the non haemotropic canine mycoplasmas and report the result of the species identification of canine mycoplasmas detected from 2006 to 2010 in Debrecen site of Central Agricultural Office Veterinary Diagnostic Directorate. The samples originating from the respiratory and genital tract were identified and differentiated by 16S-23S rrna IGS PCR-RFLP. The tested species were found to be M. canis, M. spumans, M. maculosum, M. cynos, M. edwardii and M. mucosicanis sp. nov. A. Sebestény S. Gy. Fekete:
6 VITAMIN K DEFICIENCY IN REDERIVED SPF RODENTS. CASE REPORT The main physiological function of vitamin K is the contribution in the blood clotting by helping the synthesis of prothrombin and other blood clotting compounds in the liver. Formerly all mouse stocks of the Imperial Cancer Research Fund in London were cleared from pathogens by sterile hysterectomies and cross-fostering. The imported SPF freshly littered mice were fed on diet sterilized with 2.5 Mrad gamma irradiation. The new immunodeficient stocks were affected with a high incidence of haemothorax and haemopericardium fatalities. This was remedied by raising the standard supplementation of the diet with 2.5 mg/kg menadione (Vitamin K 3 ) to 5 mg/kg by the manufacturer. After the gradual recontamination of these stocks by the successive re-entry of some pathogens during the ensuing years a fresh rederivation programme were carried out. This time to the originally germfree foster mothers a minimal basic intestinal flora (Streptococcus faecalis var. liquefaciens, Streptococcus faecium and Lactobacillus plantarum) were added. The drinking water of this poliassociated foster colony was supplemented by menadion. Fatal hemorrhagic diathesis cases reappeared but could again be eliminated by raising the menadion supplementation of the diet up to 20 mg/kg. However, occasional cases or uterine and cardiac haemorrhages still occurred, especially in some newly established transgenic mice, which had an impaired blood clotting cascade. Diet analyses revealed a great fluctuation in the
7 menadione contents between batches of diet with deficiencies aggravated by irradiation. Instead of the declared 20 mg/kg menadion, as low as 1.1 mg/kg could be detected by chemical analyses. The NRC (1995) prescribes only 1 mg phylloquinone/kg diet as minimum requirement for healthy mice with normal gut flora. On the contrary, after their several years experiences, especially for immunodeficient mice, the optimum supplementation may be set up to 150 to 200 mg/kg before pelleting or gamma irradiation. M. Z. Vidovszky S. Boldogh: DETECTION OF ADENOVIRUSES IN THE NORTHERN HUNGARIAN BAT FAUNA The authors screened samples, collected randomly from house-dwelling bats, for the presence of adenoviruses by PCR. Two novel adenoviruses were found in guano samples originating from the Aggtelek National Park and its surrounding area. Considering the results of previous studies, four new types of adenoviruses have been found in the representatives of four different bat species in Hungary. To date, samples have been collected from eight house-dwelling bat species, out of which four were found to harbour new adenoviruses. These include the Grey Long-eared Bat (Plecotus austriacus) and the Common Noctule (Nyctalus noctula) belonging to the family of Common bats (Vespertilionidae), as well as the Lesser Horseshoe Bat (Rhinolophus hipposideros) and the Greater Horseshoe Bat (R.
8 ferrumequinum) from the family of Horseshoe bats (Rhinolophidae). Based on preliminary phylogenic tree reconstructions the bat adenoviruses from different host species appear on distinct branches. S. Sikó Barabási V. Cozma: OCCURRENCE OF ECHINOCOCCUS MULTILOCULARIS AND ALVEOLAR ECHINOCOCCOSIS IN ROMANIA Between , 561 small intestine samples and 176 faces samples from foxes, and 364 wild rodents were examined in 15 counties from the north-western and central part of Romania, searching internal parasites, especially the presence of E. multilocularis and its larval form, echinococcus alveolaris. The scrapings of the small intestinal mucosa were examined by microscope, and the faeces with ELISA coproantigen test. To determine the taxonomy of the found Echinococcus species PCR multiplex method was used. The liver of the wild rodents were examined macroscopically and histopathologically. The results showed 4.8% E. multilocularis infestation in foxes. The PCR method confirmed the presence of E. multilocularis species. The coproantigen-elisa examination of faeces indicated 17.0% prevalence of Echinococcus infection. Echinococcus alveolaris was found in 13 (3.6%) of the examined 364 potential intermediate hosts. Fertility of these cysts was 53.8%. In laboratory conditions the authors succeeded to induce experimentally the echinococcus alveolaris infection in white mice.
Rev. sci. tech. Off. int. Epiz., 2000,19 (2), 443-462 Newcastle disease and other avian paramyxoviruses D.J. Alexander Central Veterinary Laboratory, Weybridge, New Haw, Addlestone, Surrey KT15 3NB, United
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