May 3rd, RIRC Annual Medal Symposium on: Improving Translational Studies for Spinal Cord Injury

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1 RIRC Annual Medal Symposium on: Improving Translational Studies for Spinal Cord Injury This activity has been approved for AMA PRA Category 1 Credits Newkirk Alumni Center University of California, Irvine May 3rd, 2013

2 Friday, May 3rd 12:00 pm -1:00 pm Lunch Lunch on the patio outside 7:30 am - 8:15 am Registration and Continental Breakfast Session 2 Current Pre-Clinical and Translational Studies of SCI 8:15 am - 8:30 am Introductory Remarks Dr. Oswald Steward Session 1 Setting the stage for translational studies of SCI 8:30 am - 9:15 am Keynote Speaker: Experimental Models of Spinal Cord Injury Dr. Jacqueline Bresnahan 9:15 am -10:00 am Title not given yet Dr. Michele Basso 10:00 am -10:45 am Autonomic Dysreflexia Suppresses Immune Function Dr. Phillip Popovich 10:45 am -11:30 am Keynote Speaker: The Landscape of Degeneration and Repair After Spinal Cord Injury Dr. Michael Beattie 11:30 am -12:00 pm Session 1 Q&A panel All morning speakers 1:00 pm -1:45 pm To be determined Dr. Mark Tuszynski 1:45 pm - 2:30 pm To be determined Dr. Andrew Blight 2:30 pm - 3:15 pm To be determined Dr. Wolfram Tetzlaff 3:15 pm - 4:00 pm Umbilical Cord Blood and Lithium Therapy for Chronic Spinal Cord Injury Dr. Wise Young 4:00 pm - 4:30 pm Sesssion 2 Q&A panel All afternoon speakers 4:30 pm - 4:45 pm Closing remarks Dr. Oswald Steward Session 3 Poster session and Reception 4:45 pm - 6:30 pm Poster displays and Reception Located in the Lobby and Den of Newkirk Center

3 Keynote Speakers Jacqueline Bresnahan, Ph.D Professor of Neurological Surgery Principal Investigator at Brain & Spinal Injury Center University of California, San Francisco San Francisco, California Michael Beattie, Ph.D Professor in Residence of Neurological Surgery Director of Research at Brain & Spinal Injury Center University of California, San Francisco San Francisco, California Distinguished Invited Speakers Phillip Popovich, Ph.D Professor, Department of Neuroscience Director at OSU center for Brain and Spinal Cord Repair Wexner Medical Center, Ohio State University Columbus, Ohio Michele Basso, PT, EdD Professor, Physical Therapy Associate Director at School of Health and Rehabilitation Sciences Wexner Medical Center, Ohio State University Columbus, Ohio Andrew Blight, Ph.D Chief Scientific Officer Acorda Therapeutics, Inc. Ardley, New York Improving Translational Studies for SCI The Reeve-Irvine Research Medal Symposium is a unique symposium that occurs once a year in conjunction with the Reeve-Irvine Research Medal Award. This year the symposium is focused on improving translational studies with an emphasis on learning more about current experimental models, pathophysiological mechanisms of SCI and existing translational work. We have brought together experts that have made significant contributions in SCI research in the aforementioned areas. Additionally, some of our speakers have either been involved in previous clinical trials or are currently involved in therapies that have great potential for clinical applications in the future. Wise Young, M.D., Ph.D Professor, Department of Cell Biology & Neuroscience Richard H. Schindell Chair in Neuroscience Rutgers, State of University of New Jersey Piscataway, New Jersey Wolfram Tetzlaff, M.D., Ph.D Professor, Department of Zoology, Faculty of Science Associate Director of Int. Collaborations on Repair Discoveries University of British Columbia Vancouver, BC Canada Mark Tuszynski, M.D., Ph.D Professor, Department of Neurosciences Director of the Center for Neural Repair University of California, San Diego San Diego, California

4 Topics Experimental models for SCI, translational studies for SCI, immune and neuroprotective mechanisms of SCI, outcomes and potential targets for SCI therapies. Target Audience MD: Neurological Surgery, Emergency Medicine, Physical Medicine and Rehabilitation, Orthopedic Surgery PhD: Neurology, Anatomy, Neurobiology, Bioengineering, Translational Sciences RN: Neurological Surgery, Emergency Medicine, Physical Medicine and Rehabilitation, Orthopedic Surgery Accreditation Statement The University of California, Irvine School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Designation Statement The University of California, Irvine School of Medicine designates this live activity for a maximum of 6 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. California Assembly Bill 1195 This activity is in compliance with California Assembly Bill 1195, which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. For specific information regarding Bill 1195 and definitions of cultural and linguistic competency, please visit the CME website at To attend this symposium and/or the Medal dinner, please fill out the appropriate registration forms attached. For questions please contact: Maya Hatch hatchm@uci.edu

5 Reeve-Irvine Medal Award Over forty years ago, Joan Irvine Smith, a well known Californian and philanthropist, played a lead roll in the establishment of what is now the University of California at Irvine. Following Christopher Reeve s tragic injury, and in recognition of his amazing spirit, she worked with UC Irvine to establish a spinal cord injury research center in Christopher s name. Starting with her lead gift of one million dollars, the Reeve Irvine Research Institute grew to become the world-class research facility that it is today. In 1996, the Reeve-Irvine Research Center and Joan Irvine Smith established an annual award for research in spinal cord injury. The award, originally called the Christopher Reeve Research Medal, with Christopher s blessing became the Reeve-Irvine Research Medal in The Reeve-Irvine Research Medal recognizes an individual, or individuals, who have made highly meritorious scientific contributions in the area of spinal cord repair, and whose research has stood the test of time and scrutiny. The medal includes a $50,000 cash award generously provided by Joan Irvine Smith and the Athalie R. Clarke Foundation. Their kindness has made it possible to continue to recognize the work of pioneering investigators whose work has brought us closer to cures for afflictions affecting the spinal cord. Between 1996 and 2012 twenty one exceptional researchers have received this prestigious award. The 2012 Reeve-Irvine Research Medal is awarded to Drs. Michael Beattie and Jacqueline Bresnahan for critical contributions to promoting repair of the damaged spinal cord and recovery of function. Oswald Steward, Director of the Reeve-Irvine Research Center, Actor Christopher Reeve and Joan Irvine Smith Previous Medal Recepients MARTIN SCHWAB FRED GAGE DENNIS CHOI SERGE ROSSIGNOL REGGIE EDGERTON ALBERT AGUAYO LISA MCKERRACHER MARY BUNGE STEN GRILLNER JAMES FAWCETT JERRY SILVER LLOYD GUTH 2005 CARL W. COTMAN GEOFFREY RAISMAN 2006 COREY S. GOODMAN MARC TESSIER-LAVIGNE 2007 WILLIAM C. DE GROAT 2008 SUSAN HARKEMA HUGUES BARBEAU 2009 ELZBIETA JANKOWSKA MARION MURRAY [2010 Medal Haitus] 2011 MICHAEL G. FEHLINGS CHARLES H. TATOR