Introducing the all-new PRO-II TM. Advancing the Art and Science of NPWT
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1 Introducing the all-new PRO-II TM Advancing the Art and Science of NPWT
2 Prospera PRO-II TM Portable. Compact. Lightweight. Looking for a better NPWT option for your homecare and ambulatory patients? Take a look at the all-new PRO-II. Now you can get all the features, benefits and flexibility of the PRO-I and more in a comfortable, compact package. Your patients will thank you. CPT Continuous Pressure Therapy Continuous pressure level of other brands =125mmHg Negative Pressure in mmhg VPT Variable Pressure Therapy Intermittent pressure levels of other brands = 125 0mmHg (spike) Intermittent pressure ranges of PRO-II = 80 40mmHg (gradual) PRO-II TM Recommended VPT Pressure Range Negative Pressure in mmhg PRO-II TM Recommended Continuous Pressure Range Time in minutes Time in minutes
3 The Portable PRO-II TM Means Quality of Life for Your Patients The portable PRO-II delivers all the benefits of NPWT without pain and discomfort for the patient. Lightweight and discreet, the PRO-II is portable and comfortable so your ambulatory and homecare patients can get on with their lives. FEATURES Contoured design for patient comfort Virtually silent operation Discreet, disposable canister Over 24-hour battery run time Carrying case that can be worn on the waist or over the shoulder Lower pressure settings enhance comfort during use VPT provides intermittent pressure in the form of a gentle massage effect eliminating painful high to low spikes characteristic of traditional intermittent pressure BENEFITS Flexible, easy to use settings with CPT (Continuous) or VPT (Variable) Pressure Therapies Contoured design makes pump easy to wear at the waist or over the shoulder Reduces pain and discomfort with wear time and dressing changes Alleviates excruciating dressing changes because moist AMD TM * Gauze under negative pressure will not adhere to the wound or allow in-growth of new tissue Reduces the need for narcotic medication prior to dressing changes VPT Variable Pressure Therapy The literature has confirmed that intermittent negative pressure increases blood flow to the wound site more effectively than continuous negative pressure and that proliferation of new granulation tissue is significantly higher. But until now, pumps available on the market were not able to provide practical, comfortable intermittent therapy. New Prospera VPT technology is engineered to deliver comfortable, massaging intermittent pressure therapy for best results and patient comfort. Pressure levels and time settings for high and low pressures are completely customizable Recommended pressures of between -40 and -80mmHg are calibrated to increase and decrease in comfortable 5mmHg increments providing a gentle massage effect Discomfort and pain due to sudden high to low pressure spikes is virtually eliminated Negative pressure is always maintained at the wound site because pressures never drops to 0mmHg Dressing Protocol is Simple for You, Painless for Your Patients AMD TM gauze dressings are proven, safe and extremely cost effective. In our judgment, antimicrobial gauze is a superior dressing for NPWT. Consider these benefits: Easy to apply to oddly shaped, tunneled and undermined wounds Can be removed from the wound in one piece decreasing the danger of the dressing fragments being left in the wound bed Delivers superior and proven antimicrobial protection Moist AMD TM gauze under NPWT will not adhere to the wound and will not allow for in-growth of granulation tissue into the dressing Decreases the need for narcotic pain medications during excruciating dressing changes Reduces nursing time required for dressing changes Allows clinician to read the wound at the wound site by assessing the present exudate, not exudate that has separated in the collection canister * AMD is a Trademark of Covidien AG
4 Case Study References 1 Wackenfors A, Sjogren J, Gustafsson R, Algotsson L, Ingemansson R, Malmsjo M. Effects of vacuum-assisted closure on inguinal wound edge microvascular blood flow. Wound Repair and Regeneration Nov-Dec;12(6): Wackenfors A, Gustafsson R, Sjogren J, Algotsson L, Ingemansson R, Malmsjo M. Blood flow responses in the peristernal thoracic wall during vacuum-assisted closure therapy. Ann Thorac Surg 2005; 79: Malmsjo M, Ingemansson R, Martin R, Huddleston E. Negative Pressure wound therapy using gauze or polyurethane open cell foam: similar effects on pressure transduction and wound contraction. Poster. June , Toronto. 3rd World Congress of the World Union of Wound Healing Societies. 4 Malmsjo M Ingemansson R, Martin R, Huddleston E. Negative pressure wound therapy using gauze or polyurethane open cell foam; similar effects on wound edge microvascular blood flow. Poster. June , Toronto. 3rd World Congress of the World Union of Wound Healing Societies. 5 Webb LX. New techniques in wound management: vacuum-assisted wound closure. J Am Acad Orthop Surg, Vol 10, No 5, September/October 2002, Lindstedt S, Malmsjo M, Gesslein B, Ingemansson R. Evaluation of continuous and intermittent myocardial topical negative pressure. J Cardio Med. August (8): Lindstedt S, Malmsjo M, Ingemansson R. The effect of different topical negative pressures on microvascular blood flow in reperfused myocardium during hypothermia. Innovations. September (5): Molnar JA., The Science Behind Negative Pressure Wound Therapy. Ostomy Wound Management April Vol. 50 Issue 4A (Suppl). 9 Chariker ME, Jeter KF, Tintle TE. Effective management of incisional and cutaneous fistulae with closed suction wound drainage. Contemporary Surger. 1989:34: Isago T, Nozaki M, Kikuchi Y, Honda T, Nakazawa H. Effects of Different Negative Pressures on Reduction of Wounds in Negative Pressure Dressings. The Journal of Dermatology Aug; 30(8): Angelique M. Reitsma, M.D. and George T. Rhodeheaver, Ph.D, Effectiveness of a New Antimicrobial Gauze Dressing as a Bacterial Barrier; University of Virginia Health System, Charlottesville, Virginia. 9/ Glenda J. Motta, RN, MPH, ET, President, GM Associates, Inc., Mitchellville, MD; Lisa Q. Corbett, APRN, MSN, CWCN, Connecticut Clinical Nursing Associates; Impact Of An Antimicrobial Gauze Upon Bacterial Colonies in Wounds That Require Packing. Ostomy Wound Management 2004 Aug: 50(8): Diane L. Krasner, PhD, RN, CWOCN, CWS, FAAN, Managing Wound Pain in Patients with Vacuum-Assisted Closure Devices, Ostomy/Wound Management ISSN: Volume 48 Issue 5 May 2002 Pages: Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg 1997; 38: Krizek TJ, Robson MC. The evolution of quantitative bacteriology in wound management. Am J Surg 1975; 130(5): Robson MC, Heggers JP. Delayed wound closure based on bacterial counts. J Surg Oncol 1970;2(4): Robson MC, Heggers JP. Bacterial quantification of open wounds. Mil Med 1969; 134(1): Fleischmann W, Strecker W, Bombelli M, Kinzl L. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg 1993; 96(9): Philbeck TE, Whittington KT, Millsap MH, Briones RB, Wight DG, Schroeder WJ. The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare Medicare patients. Ostomy Wound Management 1999; 45(11): Saxena SM, Hwang CW, Huang S, Eichbaum Q Ingber D, Orgill DP. Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg Oct; 114(5): ; Discussion Armstrong DG, Lavery LA, Abu-Rumman P, et al, Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot. Ostomy Wound Management Apr; 48(4): Clare MP, Fitzgibbons TC, McMullen ST, Stice RC, Hayes DF, Henkel L. Experience with the vacuum assisted closure negative pressure technique in the treatment of non-healing diabetic and dysvascular wounds. Foot Ankle Int 2002 Oct; 23(10): Fabian TS, Kaufman HJ, Lett ED, Thomas JB, Rawl DK, Lewis PL, Summitt JB, Merryman JI, Schaeffer TD, Sargent LA, Burns RP. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full-thickness wound healing. Am Surg 2000; 66(12): Wound was the result of flap surgery and graft surgery to treat cancer of the bone and skin. The wound circumvented the left forearm. Surgeon was considering amputation. Patient Profile Age/Gender: 73 year-old female Co-Morbidities: Left arm bone/skin neoplasm post surgical resection, HTN, CVA with right sided weakness, hyperlipidemia, Hx heroin use. Comments: Foam NPWT initiated at acute care hospital. Admitted to LTAC and switched to Gauze NPWT. Patient noted significant decrease in pain. Wound Profile Exudate: Moderate, fully-controlled Dressing Frequency: 3x per week NPWT Setting: Week 1: -80mmHg continuous Day 8 Day 31: Variable Pressure Therapy: -80mmHg 3 min/-40mmhg 3 min Length of NPWT Therapy: 31 days* Day 12 Day 1 Day 31 * Therapy was discontinued on day 31 when wound became shallow and granulation tissue covered the radial tendons. The wound was closed by secondary intention.
5 The Science of Negative Pressure Wound Therapy Intermittent Therapy Recommended for Best Results A strong and growing number of studies have found that intermittent negative therapy increases blood flow to the wound site more effectively than continuous negative pressure and that proliferation of new granulation tissue is significantly higher (63.4%) over continuous negative pressure. One theory regarding increased blood flow is that this may be due to the fact that during higher pressure settings there is increased perfusion of blood flow to the wound with a hypoperfused halo at the wound edge. As pressure levels decrease this halo decreases as blood flow disperses into the surrounding tissue minimizing possible ischemic effects. Low Levels of Continuous Pressure Recommended Recent research indicates that lower pressure may be beneficial especially in soft tissue to minimize ischemia in the hypoperfused zone surrounding the wound edge. Research done at the Lund University Medical Center recommends levels of -80mmHg for soft tissue and slightly higher for muscle tissue. Basic Mechanisms of Negative Pressure Wound Therapy The responses of wounds to NPWT are the result of controllable and equally distributed negative pressures, not from the particular dressing and drain combinations used to apply negative pressure therapy. Three leading mechanisms of action are thought to contribute to the wound healing benefits of NPWT therapy. n Vacuum Assisted Drainage The removal of excess exudate is the first mechanism. The fluid removed contains microorganisms, debris, proteolytic enzymes, and other components which can prolong inflammation and edema, and delay healing. Removal of this exudate results in antimicrobial control and maintenance of a moist environment important for healing. n Reduction of Interstitial Fluid Removal of interstitial fluid reduces edema, which decompresses the tissues. As a result, capillary blood flow is increased, allowing for improved perfusion, angiogenesis, and increased supplies of oxygen, nutrients and growth factors important for healing. Increased blood flow and perfusion also improves access for infection-fighting cells. n Mechanical Effects on Blood Flow, Cell Growth and Cell Proliferation NPWT produces mechanical stress and a pressure gradient across tissue that results in surges of blood flow to the wound area. In addition, NPWT places physical strain on cells, stimulating them to interact with soluble growth factors in the extracellular matrix. This effect is often referred to as cell stretch. The stretched cells begin proliferating, dividing, and maturing, leading to the growth of new vessels, collagen deposition, and granulation tissue formation.
6 Prospera offers a complete line of pumps, disposable wound dressing kits, collection canisters, and an assortment of silicone drains. Indications for Use The PRO-II TM Negative Pressure Wound Therapy System is indicated for patients who would benefit from a suction device, particularly as the device may promote wound healing. Contraindications When used for wound healing, the PRO-II is contraindicated in the presence of: Necrotic tissue. Unexplored or non-enteric fistulas. Untreated osteomyelitis. Wounds containing malignant tissue. Exposed arteries, veins, or organs. Precautions Precautions should be taken in the presence of: Anticoagulation or active bleeding. Difficult wound hemostasis. Close proximity of blood vessels, organs, muscle, and fascia requiring adequate protection. Irradiated vessels and tissue. Bony fragments. Untreated malnutrition. Non-compliance. Technical Data Air-flow rate of pump liters/min Negative pressure... Max. 200mmHg (Conversion factor: 1kPa ~ 7.5mmHg) Nominal voltage of power supply adapter V primary, 12VDC secondary Power requirements V, 50/60Hz, 45W Maximum load current A Mains frequency of power supply adapter... 50/60Hz Nominal voltage of electronic circuit board... 12V Power consumption W (charging operation)/10w (charging only) Current consumption A Rechargeable battery V, 4.4Ah lithium-ion battery Charging time of empty battery hours half empty battery hours Dimensions (W x H x D) " x 6.5" x 3.5" Weight (basic unit) kg (2.65 lbs.), with canister Operating time AC operation: continuous operation DC operation: approx hours, depending on use Degree of protection according to IEC Type BF Risk class according to 93/42/EEC, IX IIa Sound emission... 35dB (A) Protection class according to IEC II Prospera 2831 Bledsoe Street Fort Worth, TX P: NPWT (6798) F: NPWT (6798) info@prospera-npwt.com Prospera All Right Reserved. Printed in USA MR /08
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