CEBO: organizational position in Masaryk Univerzity

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1 CENTRE OF BIOSTATISTICS AND ANALYSES Faculty of Medicine & Faculty of Science Masaryk University, Brno, Czech Republic CEBO: organizational position in Masaryk Univerzity Kamenice 126/3, Brno, Czech Republic Faculty of Medicine, Masaryk University, Brno Faculty of Science, Masaryk University, Brno

2 Centre of Biostatistics and Analyses cba.muni.cz is professional IT provider, SW developer and guarantee of data analyses The Centre of Biostatistics and Analyses (CBA) was established in 2001 as inter-faculty institute of Masaryk Univerzity in Brno, Czech Republic. As an academic institute, CBA has the following mission: 1) Education and research in the field of applied data analysis and ICTs for biological and clinical disciplines 2) Professional service and guaranty for clinical trials and health care registries (data analysis, software development, internet services) 3) To develop newly established study program Computational Biology in the Czech Republic CBA, Faculty of Science, Faculty of Medicine, Masaryk University, Kamenice 126/3, Brno, Czech Republic, Regarding clinical registries and clinical trials, CBA closely collaborates with participating clinical centers and works under the guarantee of professional societies. Faculty of Science, Masaryk University, Brno Faculty of Medicine, Masaryk University, Brno

3 Centre of Biostatistics and Analyses cba.muni.cz Academic institute -> Established in > 40 employees -> > 65 scientific projects Structure /divisions/ -> Data analysis -> Clinical trials -> Environmental informatics -> SW development & ITC Research and teaching -> Computational biology -> Ecological risk assessment -> Human risk assessment -> Evidence-based medicine

4 CEBO is coming to new environment Centre of Biostatistics and Analyses Institute of Biostatistics and Analyses

5 CEBO is a part of newly established IBA IBA PřF MU IBA LF MU Division of environmental informatics Economic department Division of clinical trials Division of data analysis Division of ICT and SW development

6 CEBO is supported by newly established IBA IBA PřF MU Economic department Division of environmental informatics Organization Contract service IBA LF MU Division of clinical trials Education Data analysis SW support Division of data analysis Division of ICT and SW development

7 Position of CEBO + Independent academic department + Prepared for complex service in the field of interest + Professional support to clinical projects in all steps during their life cycle trajectory + Open for both national and international collaboration - Financial sources?

8 Management & functionality of CEBO EXECUTIVE MANAGEMENT Management of MU SCIENTIFIC MANAGEMENT Management of IBA Nemocnice Chomutov Masarykova nemocnice Ústí nad Labem Nemocnice Liberec FN Plzeň FN KV Praha FN Motol Praha KOC Praha a Středočeský kraj FN Hradec Králové Nemocnice Pardubice FN Ostrava CEBO Office Executive manager Professional team Nemocnice České Budějovice Nemocnice Jihlava MOÚ Brno FN Brno FN u sv. Anny Brno FN Olomouc Nemocnice Zlín Program committee Advisory board Nemocnice Nový Jičín

9 Management & functionality of CEBO INPUTS Initiation of projects /national, international/ Project based on collaboration Ideas, proposals, hypotheses Problems to be solved OUTPUTS Advice, theoretical support Educational support Feasibility studies Project design Methodical support Partial services Project management

10 Methodical background of CEBO Effective and friendly system for data collection More users with central data management Open on-line system based on ORACLE technology

11 Methodical background of CEBO Secure environment data entry Local Computer Web Server (Secure web-based based communication) 128 bit SSL Database Server (Oracle 9i Server) Fully guaranteed, authorized system

12 Methodical background of CEBO Standardized environment for multicentric projects Individual centers Presentations and studies realised in individual centers can use central analytic support Data of centers Common reports Central database Common outputs are accessible to all participants, special application is based on agreement Outputs Data coding and analyses Registration records Electronic records Overall outputs // internet presentations //.

13 SW solution Methodical background of CEBO Predefined user controlled analytic tools Comprehensive presentations with comments and access to appropriate analytic tools Data browser - analysis of individual parameters

14 Information background of CEBO About project News Epidemiological analyses Publications, reports Software SVOD Analytic tools tutorial Portal solution Incidence and mortality Time trends Regional overview Age analyses Clinical stages Epidemiological analyses International data Comparative standards Comprehensive overview

15 Challenges for CEBO Clinical trials Prospective, randomized research projects Evidence-based health care assessment Educational strategy in evidence-based oncology /associated with university/ Beneficial international collaboration

16 Challenges for CEBO The Association CEEESTAHC Krakow : an International Symposium Evidence-Based Health Care 2-3. X. KRAKOW

17 THANK YOU FOR CEBO

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