Ministero della Salute

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1 Ministero della Salute Direzione Generale Ricerca Sanitaria e Biomedica e della Vigilanza sugli Enti BANDO 2010 RICERCA FINALIZZATA E GIOVANI RICERCATORI Standardizing tissue handling in pre analytical procedures: technological, environmentally safe innovation in solid tumour processing. Piemonte CLI Healthcare Delivery and Development of new IVD CE molecular diagnostic tests for the detection of epigenetic defects involved in human disease MAGGIORE BIO Genes, Genomes and Genetics (1) Nerve Growth Factor eye drops as a novel treatment for vision loss in patients with Retinitis Pigmentosa: from preclinical to clinical Phase II trial. SAN RAFFAELE MONTE TABOR CLI Brain Disorders and IMMUNOLOGICAL IMPACT OF SILIBININ TREATMENT FOR HCV RECURRENCE IN STABLE LIVER TRANSPLANTED PATIENTS Puglia CLI Immunology Planar haptic device and virtual reality tools for hand and finger rehabilitation S.CAMILLO CLI Musculoskeletal, Oral and UNRESECTABLE IN TRANSIT METASTATIC MELANOMA: ELECTROCHEMO THERAPY VERSUS ELECTROIMMUNOTHERAPY. LOCAL AND SYSTEMIC EFFECTS. PASCALE CLI Oncology 2 Translational 8, Hyperthophic cardiomyopathy: new insights from deep sequencing and psycosocial evaluation. Lombardia CLI Cardiovascular and 8, Pagina 1 di 6

2 CERVICAL PLETHYSMOGRAPHY: A NEW TOOL FOR NON INVASIVE ASSESSMENT OF CEREBRAL VENOUS RETURN, AND A POSSIBLE SCREENING DEVICE FOR CHRONIC CEREBROSPINAL VENOUS INSUFFICIENCY Emilia Romagna CLI Vascular and Hematology Porous titanium combined with an osteoinductive hydrogel and cells: an innovative strategy to improve prosthetic implants osteointegration GALEAZZI BIO Musculoskeletal, Oral and Improved pre surgical evaluation of the human epileptogenic zone with a novel intracranial recording/analysis platform CARLO BESTA BIO Brain Disorders and 9, Role of SAMITAL in prevention of chemo radiation (CT/RT) induced oral mucositis in cancer patients. A Phase 2 Randomized Controlled trial in adults and a feasibility study in paediatric patients I. O. V. CLI Oncology 2 Translational Cancer biomarker detection using microstructured/super hydrophobic surfaces and advanced spectroscopy techniques Calabria BIO Bioengineering Sciences and Technologies Development and optimization of a dedicated selfshielded system to perform accelerated partial breast irradiation in prone position after breast conserving surgery. REGINA ELENA CLI Oncology 2 Translational Development of brain targeted epigenetic drugs for the treatment of neurodegenerative disorders and brain ischemia S.CAMILLO BIO Brain Disorders and Cost Utility of Conventional Hemodialysis (CHD) versus Short Daily Hemodialysis (SDHD) for patients coming from Automated Peritoneal Dialysis (APD): A randomized controlled trial Puglia CLI Healthcare Delivery and A new automatic device for personalized clinical monitoring of thrombotic and hemorraghic risk assessment in cancer patients C.R.O. AVIANO BIO Oncology 2 Translational Pagina 2 di 6

3 Docetaxel, Cisplatin and 5 Fluorouracil followed by concomitant Radiotherapy and PF in Locally advanced Head and Neck carcinoma: A phase II study proposal Lombardia CLI Oncology 2 Translational 10, (1) ß amyloid control of peripheral and neuronal glucose uptake NEUROMED BIO Brain Disorders and 10, DOSE WARPING METHODS FOR IGRT AND ADAPTIVE RT: DOSE ACCUMULATION BASED ON ORGAN MOTION AND ANATOMICAL VARIATIONS OF THE PATIENTS DURING RADIATION THERAPY TREATMENTS Emilia Romagna BIO Oncology 2 Translational 10, FREMS for Acute Inflammatory Bowel Disease: a Phase I/II trial Lazio CLI Digestive, Kidney and Urological Systems 10, Sebum lipidomics: a new tool to correlate skin and systemic lipid metabolism. SAN GALLICANO BIO Musculoskeletal, Oral and Use of a new material (polipropilene biofilm) with coated nanoparticles for the release of antibacterial drugs instead of surgical mesh for the reconstructive surgery of pelvic floor. Lazio BIO Digestive, Kidney and Urological Systems A Phase II Randomized Multicentre Study of SystemicChemotherapy versus Systemic Chemotherapy plus SIR Spheres as SecondLine in KRAS Mutant Unresectable Colorectal Liver Metastases (SITILO 2) Lazio CLI Oncology 2 Translational GOAL DIRECTED PERFUSION AND ACUTE KIDNEY INJURY IN CARDIAC SURGERY A RANDOMIZED, CONTROLLED TRIAL SAN DONATO CLI Surgical Sciences, Biomedical Imaging, and Bioengineering Metabotropic glutamate receptors as a target for the treatment of Amyotrophic Lateral Sclerosis NEUROMED BIO Brain Disorders and Pagina 3 di 6

4 Phase II trial of fulvestrant and gefitinib combination in patients with EGFR mutations who failed a first line with EGFR Tyrosine Kinase Inhibitors (TKIs) ISTITUTO TUMORI MILANO CLI Oncology 2 Translational Integrated lipidomic profiling in diabetes, cardiovascular disease and cancer in a cohort of subjects in a mediterranean area of southern Italy: a nested case control study. DE BELLIS BIO Population Sciences and Epidemiology Haemophilia arthropathy (HA) and Ultrasound (US): development and first validation steps of the simplified HEAD US score Liguria CLI Musculoskeletal, Oral and Type 3 metabotropic glutamate receptors expressed by cancer stem cells as drug targets in the experimental treatment of malignant gliomas NEUROMED BIO Brain Disorders and ANTIOXIDANT TREATMENT TO PREVENT BIOMEDICAL HAZARDS OF CYCLIC VARIATIONS OF SOLAR ACTIVITY SAN DONATO BIO Endocrinology, Metabolism, Nutrition and Reproductive Sciences 13, Effect of telemedicine on Haemophilia Management, Treatment Effectiveness and Patient's Quality of Life Abruzzo CLI Healthcare Delivery and 14, Calcium handling proteins common gene variants for the prediction of life threatening arrhythmias in ICD recipients with heart failure NEUROMED BIO Cardiovascular and Development of pre operative investigation tools and surgical procedures for the treatment of movement disorders in childhood OSPEDALE BAMBINO GESU' BIO Brain Disorders and Comparison of next generation sequencing based identification of translocations with copy number alteration based identification of deletions for the development of patient/tumor specific real time PCR assays for detection of minimal residual disease usin IRCCS AOU San Martino IST (Genova) CLI Oncology 2 Translational 16, Pagina 4 di 6

5 Development of a miniaturized, automated assay for the diagnosis of rare diseases Piemonte BIO Bioengineering Sciences and Technologies Intensive nutritional counseling in cancer patients undergoing radiotherapy: a randomized controlled trial. SAN MATTEO CLI Oncology 2 Translational InTeReSt Project. Integrated Tecnological Rehabilitation of Stroke. Upper limb rehabilitation: efficacy of robot versus neuromodulation treatment and assessment of adaptive central peripheral plasticity DON GNOCCHI CLI Emerging Technologies and Training in s Honey and other hive products free from pharmaceutical or environmental residues: innovative, automated honey bee farming system Istituto Zooprofilattico Sperimentale del Lazio e della Toscana BIO Veterinary early detection of cardiotoxicity in cancer patients ONCOLOGICO DI BARI CLI Cardiovascular and 18, The overexpression of ANGPTL4 is involved in the inhibition of proliferation of human gastric cancer cell line MKN 45. Study of the effects of ANGPTL4 in invasiveness and metastasis. Development of effective approach for cancer therapy. PASCALE BIO Oncology 1 Basic Translational 19, Laser Treatment of Haemophilic Hypertrophic Synovia Toscana CLI Musculoskeletal, Oral and 20, Study and control of anticipatory movements followed to adaptation of sequential learned motorial gestures related to subjects intensively trained: FMRI and DTMRI study NEUROLESI BIO Integrative, Functional, and Cognitive Impact assessment of Training Centre for Integrated Health Emergency Emilia Romagna CLI Healthcare Delivery and Project title: Safety and Effectiveness of H.E.L.P. apheresis in microcirculatory diseases refractory to standard care Emilia Romagna CLI Cardiovascular and 21, Pagina 5 di 6

6 "Preventative strategies against dementia: clinical, biological and anthropological impact of long term treatment with anti oxidants in mild cognitive impairment" Umbria CLI Brain Disorders and 23, LEGENDA NOTE: NOTA 1 = Il PI del Progetto ha richiesto un finanziamento inferiore a quello minimo previsto dal Bando NOTA 2 = Principal Investigator non è operatore SSN NOTA 3 = Il Progetto è risultato uguale ad altro progetto presentato nello stesso Bando anche se in altra sezione Pagina 6 di 6

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