Recombinant Antibody Fragments, Brochure

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Recombinant Antibody Fragments, Brochure"

Transcription

1 Recombinant Antibody Fragments, Brochure Interest in any of the products, request or order them at Bio-Connect Diagnostics. Bio-Connect Diagnostics B.. T NL +31 (0) T BE +32 (0) Begonialaan 3a F NL +31 (0) F BE +32 (0) TE Huissen E The Netherlands W

2 Recombinant Antibody Fragments Single Chain F (ScFv)

3 Recombinant Antibody Fragments Single Chain Fv (ScFv) Randox Life Sciences Randox Life Sciences offers high quality, cost effective human recombinant proteins, polyclonal and monoclonal antibodies and recombinant fragments to classic and novel targets. Our extensive range of life science products can be utilised in a number of applications including ELISA, western blot analysis, flow cytometry, immunohistochemistry and immunoaffinity purification. ariable Region Single chain Fvs (ScFvs) are recombinant antibody fragments, which commonly consist of the variable (antigen binding) region of an immunoglobulin heavy chain covalently linked to the corresponding region of an immunoglobulin light chain. These regions are usually expressed in E.coli as a single continuous sequence, which are separated by a short linking amino acid sequence. ScFvs have multiple benefits over traditional monoclonal antibodies due to their greatly reduced size and ease of genetic manipulation. All Randox ScFvs are expressed from the DNA of pre-immunised sheep. ScFv (Single chain Fv) Structure H Advantages of ScFvs Small size - Increased coating concentrations - Better sample penetration - Higher yield Less interference Scfvs have no Fc region Quick Expression easily scalable for bulk orders Genetically engineered fusion Tags - Immobilisation - Detection - Conjugation - Purification DNA sequenced and stored, guarantees future antibody supply Epitope mapping available Primary manufacturer - expertise and technical assistance - Can offer advice on epitope targeting and potential pairing of antibodies - Low cost - Custom projects including novel targets, tags and formats Heavy Chain Light Chain L Constant Region What are ScFvs? H IgG 150 kda L ScFv 30 kda General Specification Host: E. Coli Format: Single Chain Fv recombinant antibody fragment ph: 7.4 Buffer: PBS containing 0.09% sodium azide preservative Storage: Stable at 4 C, long term storage at -20 C Purity: Affinity Purified to >90%

4 How do ScFvs compare to traditional antibody molecules? Activity/Sensitivity - All Randox ScFv fragments are tested for high affinity binding to the immunogen and where possible to native (human) forms of the antigen. Specificity - All Randox ScFv fragments are tested for non-specific binding against a panel of related or unrelated antigens. Stability - All Randox ScFv fragments are tested for stability at higher temperatures in accelerated stability studies - All Randox ScFvs are certified for storage at 4 C with -20 C recommendedfor long term storage. Recombinant Antibody Fragments Available Randox Life Sciences now offer a catalogue of novel in-house manufactured ScFv products and can also provide a custom service for the isolation and production of novel ScFv fragments upon request. Cardiac troponin I (ctni) Plasminogen activator inhibitor-1 (PAI-1) L-selectin FABP3 (heart fatty acid binding protein or FABPh) p53 antibody Plasminogen activator inhibitor-1 (PAI-1) Thyroid-stimulating hormone (TSH) TSH / HCG / LH / FSH α-chain Tetanus Toxoid Alpha 1 acid glycoprotein (AAG or AGP) soluble EGFR-1 (segfr1 or FLT-1) Tropomyosin 1 (TPM alpha or TPM1) FABP8 (myelin fatty acid binding protein) FABP7 (brain fatty acid binding protein) TSH / HCG/LH/FSH Hepatitis B Surface Antigen (HBsAg) Haptoglobin Beta Norketamine Inter-cellular adhesion molecule 1 (ICAM-1 or CD54) human immunoglobulin M (IgM) Full epitope data for cardiac Troponin I ScFvs makes assay development easier! ctni Epitope (amino acid seq.) ScFv Clone ID Cat No F9 RAF A6 RAF A4 RAF F10 RAF A2 RAF F9 RAF H4 RAF D7 RAF D1 RAF D11 RAF F4 RAF9406 Sandwich Assay detecting Cardiac Troponin I using Randox scfv capture and conjugate pair Signal (RLUs) Concentration of Cardiac Troponin I (ng/ml) * Assay performed on the Randox Investigator analyser

5 What are ScFvs useful for? ELISA Immunohistochemistry Flow cytometry Immunoaffinity purification Western blotting Other immunological methods ScFv Catalogue 46 ScFv clones against 18 different targets ScFvs against markers for cardiovascular disease, thyroid function, infectious agents and other disease conditions Multiple clones per target Ideal for assay development Can offer advice on epitope targeting and potential pairing of antibodies Custom projects including novel targets, tags and formats Order online Randox Laboratories Limited, 55 Diamond Road, Crumlin, County Antrim, BT29 4QY, United Kingdom T +44 (0) F +44 (0) E I Information correct at time of print. All Randox products are made in the UK. Randox Laboratories Limited is a company registered within Northern Ireland with company number N.I AT Registered Number: GB Product availability may vary from country to country. Please contact your local Randox representative for information. LT312 FEB13

Monoclonal Antibodies, Brochure

Monoclonal Antibodies, Brochure Monoclonal Antibodies, Brochure Interest in any of the products, request or order them at Bio-Connect Diagnostics. Bio-Connect Diagnostics B.V. T NL +31 (0)26 326 44 60 T BE +32 (0)2 502 12 53 Begonialaan

More information

Custom Antibodies & Recombinant Proteins

Custom Antibodies & Recombinant Proteins Custom Antibodies & Recombinant Proteins INTRODUCTION Custom services to meet your research and development requirements Improvements in health, medicine and diagnostics over the past century can be largely

More information

CUSTOM ANTIBODIES & RECOMBINANT PROTEINS

CUSTOM ANTIBODIES & RECOMBINANT PROTEINS CUSTOM ANTIBODIES & RECOMBINANT PROTEINS INTRODUCTION Custom services to meet your research and development requirements Improvements in health, medicine and diagnostics over the past century can be largely

More information

KMS-Specialist & Customized Biosimilar Service

KMS-Specialist & Customized Biosimilar Service KMS-Specialist & Customized Biosimilar Service 1. Polyclonal Antibody Development Service KMS offering a variety of Polyclonal Antibody Services to fit your research and production needs. we develop polyclonal

More information

Frequently Asked Questions (FAQs): Antibodies General

Frequently Asked Questions (FAQs): Antibodies General Frequently Asked Questions (FAQs): Antibodies General Should I choose mab or pab? The production of antibodies involves the immunisation of one or more animals with an antigen in order to elicit an immune

More information

3 months 1.5 months 1.5 months. 1 month

3 months 1.5 months 1.5 months. 1 month Rabbit monoclonal antibody (Mab) is secreted by the plasma B-cell of the rabbit. Traditional generation of rabbit Mab relies on a rabbit myeloma for B- cell fusion (

More information

HuCAL Custom Monoclonal Antibodies

HuCAL Custom Monoclonal Antibodies HuCAL Custom Monoclonal HuCAL Custom Monoclonal Antibodies Highly Specific, Recombinant Antibodies in 8 Weeks Highly Specific Monoclonal Antibodies in Just 8 Weeks HuCAL PLATINUM (Human Combinatorial Antibody

More information

CUSTOM ANTIBODIES. Fully customised services: rat and murine monoclonals, rat and rabbit polyclonals, antibody characterisation, antigen preparation

CUSTOM ANTIBODIES. Fully customised services: rat and murine monoclonals, rat and rabbit polyclonals, antibody characterisation, antigen preparation CUSTOM ANTIBODIES Highly competitive pricing without compromising quality. Rat monoclonal antibodies for the study of gene expression and proteomics in mice and in mouse models of human diseases available.

More information

HuCAL Custom Monoclonal Antibodies

HuCAL Custom Monoclonal Antibodies HuCAL Custom Monoclonal Antibodies Highly Specific Monoclonal Antibodies in just 8 Weeks PROVEN, HIGHLY SPECIFIC, HIGH AFFINITY ANTIBODIES IN 8 WEEKS WITHOUT HuCAL PLATINUM IMMUNIZATION (Human Combinatorial

More information

Your partner in immunology

Your partner in immunology Your partner in immunology Expertise Expertise Reactivity Reactivity Quality Quality Advice Advice Who are we? Specialist of antibody engineering Covalab is a French biotechnology company, specialised

More information

ELITE Custom Antibody Services

ELITE Custom Antibody Services ELITE Custom Antibody Services ELITE Custom Antibody Services Experience, confidence, and understanding As a manufacturer and service provider, we have the experience, confidence, and understanding to

More information

Custom Antibody Services

Custom Antibody Services Custom Antibody Services Custom service offerings DNA sequence Plasmid Peptide Structure Protein Peptide Small molecule Cells Spleen Lymphocytes Antigen Preparation Immunization Fusion & Subcloning Expansion

More information

Genes to Proteins to Antibodies

Genes to Proteins to Antibodies Genes to Proteins to Antibodies About Us Fusion Antibodies is a CRO established in 2001 as a spin-out from Queen s University Belfast. The company building is situated in a charming area of Springbank

More information

Chapter 2 Antibodies. Contents. Introduction

Chapter 2 Antibodies. Contents. Introduction Chapter 2 Antibodies Keywords Immunohistochemistry Antibody labeling Fluorescence microscopy Fluorescent immunocytochemistry Fluorescent immunohistochemistry Indirect immunocytochemistry Immunostaining

More information

Geniron. Custom Antibody Services. Serum services Antibody Monoclonal. Purification Antibody Mono Y Genetic Immunization Genbody Polyclonal Antibody

Geniron. Custom Antibody Services. Serum services Antibody Monoclonal. Purification Antibody Mono Y Genetic Immunization Genbody Polyclonal Antibody Geniron Custom Antibody Services Serum services Antibody Monoclonal Purification Antibody Mono Y Genetic Immunization Genbody Polyclonal Antibody Geniron Poly Y WE PROVIDE OUR SERVICES TO With Expertise

More information

1.Gene Synthesis. 2.Peptide & Phospho-P. Assembly PCR. Design & Synthesis. Advantages. Specifications. Advantages

1.Gene Synthesis. 2.Peptide & Phospho-P. Assembly PCR. Design & Synthesis. Advantages. Specifications. Advantages 1.Gene Synthesis Assembly PCR Looking for a cdna for your research but could not fish out the gene through traditional cloning methods or a supplier? Abnova provides a gene synthesis service via assembly

More information

Integrated Protein Services

Integrated Protein Services Integrated Protein Services Custom protein expression & purification Version DC04-0012 Expression strategy The first step in the recombinant protein generation process is to design an appropriate expression

More information

Advanced BioDesign Outlines Solutions. Antibody Overview. by Advanced BioDesign. Project Start. Immunogenicity. Selecting Your Antigen

Advanced BioDesign Outlines Solutions. Antibody Overview. by Advanced BioDesign. Project Start. Immunogenicity. Selecting Your Antigen Advanced BioDesign Outlines Solutions by Advanced BioDesign Antibody Overview Launching an immunisation programme is an important experimental step that needs care. With Advanced BioDesign, you may develop

More information

Custom Antibodies Services. GeneCust Europe. GeneCust Europe

Custom Antibodies Services. GeneCust Europe. GeneCust Europe GeneCust Europe Laboratoire de Biotechnologie du Luxembourg S.A. 6 rue Dominique Lang L-3505 Dudelange Luxembourg Tél. : +352 27620411 Fax : +352 27620412 Email : info@genecust.com Web : www.genecust.com

More information

MAB Solut. MABSolys Génopole Campus 1 5 rue Henri Desbruères 91030 Evry Cedex. www.mabsolut.com. is involved at each stage of your project

MAB Solut. MABSolys Génopole Campus 1 5 rue Henri Desbruères 91030 Evry Cedex. www.mabsolut.com. is involved at each stage of your project Mabsolus-2015-UK:Mise en page 1 03/07/15 14:13 Page1 Services provider Department of MABSolys from conception to validation MAB Solut is involved at each stage of your project Creation of antibodies Production

More information

Aviva Systems Biology

Aviva Systems Biology Aviva Custom Antibody Service and Price Mouse Monoclonal Antibody Service Package Number Description Package Contents Time Price Customer provides antigen protein $6,174 Monoclonal package1 (From protein

More information

Antigens & Antibodies II. Polyclonal antibodies vs Monoclonal antibodies

Antigens & Antibodies II. Polyclonal antibodies vs Monoclonal antibodies A Brief Review of Antibody Structure A Brief Review of Antibody Structure The basic antibody is a dimer of dimer (2 heavy chain-light chain pairs) composed of repeats of a single structural unit known

More information

Antibodies Against Fluorescent Proteins

Antibodies Against Fluorescent Proteins Antibodies Against Fluorescent Proteins Section C - A collection of antibodies for the detection of Evrogen Fluorescent Proteins in different applications. Contents Overview............................................

More information

Guide to Purification of Polyclonal Antibodies

Guide to Purification of Polyclonal Antibodies Guide to Purification of Polyclonal Antibodies When choosing a polyclonal antibody, either as a primary or secondary antibody in an immunoassay, researchers are often inundated with an array of antibody

More information

The Use of Antibodies in Immunoassays

The Use of Antibodies in Immunoassays TECHNICAL NOTE The Use of Antibodies in Immunoassays Introduction Structure of an IgG Antibody Immunological reagents are the backbone of every immunoassay system. Immunoassays can be utilized to quantitatively

More information

A Novel Bioconjugation Technology

A Novel Bioconjugation Technology A Novel Bioconjugation Technology for Assay Development and More! Presentation overview Who we are Solutions we provide for our customers Solulink s technology Linking system The Solulink advantage Applications

More information

Guide to Purification of Polyclonal Antibodies

Guide to Purification of Polyclonal Antibodies Guide to Purification of Polyclonal Antibodies When choosing a polyclonal antibody, either as a primary or secondary antibody in an immunoassay, researchers are often inundated with an array of antibody

More information

Superior TrueMAB TM monoclonal antibodies for the recognition of proteins native epitopes

Superior TrueMAB TM monoclonal antibodies for the recognition of proteins native epitopes Superior TrueMAB TM monoclonal antibodies for the recognition of proteins native epitopes Outlines Brief introduction of OriGene s mission on gene-centric product solution. TrueMAB monoclonal antibody

More information

THE His Tag Antibody, mab, Mouse

THE His Tag Antibody, mab, Mouse THE His Tag Antibody, mab, Mouse Cat. No. A00186 Technical Manual No. TM0243 Update date 01052011 I Description.... 1 II Key Features. 2 III Storage 2 IV Applications.... 2 V Examples - ELISA..... 2 VI

More information

IMMUNOASSAY CONTROL - LEVEL 1 (IA CONTROL 1)

IMMUNOASSAY CONTROL - LEVEL 1 (IA CONTROL 1) 0843 IMMUNOASSAY CONTROL - LEVEL 1 (IA CONTROL 1) Cat. No. IA2638 / IA2633 Lot No. 978EC Size: 10 x 5 ml / 12 x 5 ml Expiry: 2013-10 INTENDED USE This product is intended for in vitro diagnostic use in

More information

Elabscience Biotechnology Co.,Ltd

Elabscience Biotechnology Co.,Ltd Biotechnology Co.,Ltd Your one-stop custom antibody service Antibody is a kind of protein that is the most widely used in the fields of biology and medicine. Antibodies, as the preparations for disease

More information

Integrated Protein Services

Integrated Protein Services Integrated Protein Services Custom protein expression & purification Last date of revision June 2015 Version DC04-0013 www.iba-lifesciences.com Expression strategy The first step in the recombinant protein

More information

WHO Prequalification of Diagnostics Programme PUBLIC REPORT. Product: Genscreen ULTRA HIV Ag-Ab Number: PQDx 0096-031-00. Abstract

WHO Prequalification of Diagnostics Programme PUBLIC REPORT. Product: Genscreen ULTRA HIV Ag-Ab Number: PQDx 0096-031-00. Abstract WHO Prequalification of Diagnostics Programme PUBLIC REPORT Product: Genscreen ULTRA HIV Ag-Ab Number: PQDx 0096-031-00 Abstract Genscreen ULTRA HIV Ag-Ab with product codes 72386 and 72388, manufactured

More information

Chapter 3.2» Custom Monoclonal

Chapter 3.2» Custom Monoclonal 198 3 3.2 Custom Monoclonal 199 Mouse monoclonal antibody development Chapter 3.2» Custom Monoclonal 200 In vitro monoclonals expression service 201 Mouse monoclonal antibody additional services 202 Magnetic

More information

P R O D U C T S CATALOG 2011-2012

P R O D U C T S CATALOG 2011-2012 P R O D U C T S CATALOG 2011-2012 INSTITUTE FOR THE APPLICATION OF NUCLEAR ENERGY - INEP Banatska 31b 11080 Zemun Belgrade Serbia Tel: (+381 11) 2619 252, 2618 696, 2199 949 Fax: (+381 11) 2618 724 www.inep.co.rs

More information

Custom Antibody Services

Custom Antibody Services prosci-inc.com Custom Antibody Services High Performance Antibodies and More Broad Antibody Catalog Extensive Antibody Services CUSTOM ANTIBODY SERVICES Established in 1998, ProSci Incorporated is a leading

More information

Proteins. Learning Objectives. Optimizing electrophoresis

Proteins. Learning Objectives. Optimizing electrophoresis Proteins Michael A. Pesce, Ph.D Director of the Specialty Laboratory New York-Presbyterian Hospital Clinical professor of Pathology Columbia University Medical Center Learning Objectives Describe the electrophoresis

More information

Broad Selection of Antibodies & Antigens. for the Diagnostics Industry in North America

Broad Selection of Antibodies & Antigens. for the Diagnostics Industry in North America Broad Selection of Antibodies & Antigens for the Diagnostics Industry in North America Antibodies and Antigens for Diagnostics Diagnostics manufacturers require antibodies and antigens of proven quality

More information

Interim Progress Report R&D Project 348. Development of a Field Test Kit for Detection of Blue-Green Algal Toxins

Interim Progress Report R&D Project 348. Development of a Field Test Kit for Detection of Blue-Green Algal Toxins Interim Progress Report R&D Project 348 Development of a Field Test Kit for Detection of Blue-Green Algal Toxins Biocode Limited November 1992 R&D 348/04/A ENVIRONMENT AGENCY 135357 CONTENTS SUMMARY KEYWORDS

More information

Chapter 18: Applications of Immunology

Chapter 18: Applications of Immunology Chapter 18: Applications of Immunology 1. Vaccinations 2. Monoclonal vs Polyclonal Ab 3. Diagnostic Immunology 1. Vaccinations What is Vaccination? A method of inducing artificial immunity by exposing

More information

TRI-LEVEL CARDIAC CONTROL (CRD CONTROL 1, 2, 3)

TRI-LEVEL CARDIAC CONTROL (CRD CONTROL 1, 2, 3) TRI-LEVEL CARDIAC CONTROL (CRD CONTROL 1, 2, 3) CAT NO. CQ3259 LOT NOS. 3190CK, 3191CK, 3192CK SIZE: 3 x 2ml EXPIRY: 2015-02 INTENDED USE This product is intended for in vitro diagnostic use in the quality

More information

Proteins. Protein Trivia. Optimizing electrophoresis

Proteins. Protein Trivia. Optimizing electrophoresis Proteins ELECTROPHORESIS Separation of a charged particle in an electric field Michael A. Pesce, Ph.D Department of Pathology New York-Presbyterian Hospital Columbia University Medical Center Rate of migration

More information

Types, production of antibodies and Antibody/antigen interaction

Types, production of antibodies and Antibody/antigen interaction Types, production of antibodies and Antibody/antigen interaction Antibodies Secreted by B lymphocytes Great diversity and specificity: >109 different antibodies; can distinguish between very similar molecules

More information

Antibody Services from GenScript, Brochure

Antibody Services from GenScript, Brochure Services from GenScript, Brochure Interest in any of the products, request or order them at Bio-Connect. Bio-Connect B.V. T NL +31 (0)26 326 44 50 T BE +32 (0)2 503 03 48 Begonialaan 3a F NL +31 (0)26

More information

Basics of Immunology

Basics of Immunology Basics of Immunology 2 Basics of Immunology What is the immune system? Biological mechanism for identifying and destroying pathogens within a larger organism. Pathogens: agents that cause disease Bacteria,

More information

IMMUNOASSAY PREMIUM PLUS LEVEL 3 (IA PREMIUM PLUS 3)

IMMUNOASSAY PREMIUM PLUS LEVEL 3 (IA PREMIUM PLUS 3) 0843 IMMUNOASSAY PREMIUM PLUS LEVEL 3 (IA PREMIUM PLUS 3) Cat. No.: IA3111 / IA3112 Lot No.: 1130EC Size.: 12 x 5ml / 12 x 5ml Expiry.: 2014-10 INTENDED USE This product is intended for in vitro diagnostic

More information

Classic Immunoprecipitation

Classic Immunoprecipitation 292PR 01 G-Biosciences 1-800-628-7730 1-314-991-6034 technical@gbiosciences.com A Geno Technology, Inc. (USA) brand name Classic Immunoprecipitation Utilizes Protein A/G Agarose for Antibody Binding (Cat.

More information

Simplify. fy Life Sci. Antibody. Engineering

Simplify. fy Life Sci. Antibody. Engineering Antibody Simplify Engineering p plify Life Scien Sci e y Life Scie fy Life Sci IgG Fragmentation FabRICATOR Antibody Fragmentation - Rapid, recise and Gentle Utilizing the unique specificity of a novel

More information

Expression and Purification of Recombinant Protein in bacteria and Yeast. Presented By: Puspa pandey, Mohit sachdeva & Ming yu

Expression and Purification of Recombinant Protein in bacteria and Yeast. Presented By: Puspa pandey, Mohit sachdeva & Ming yu Expression and Purification of Recombinant Protein in bacteria and Yeast Presented By: Puspa pandey, Mohit sachdeva & Ming yu DNA Vectors Molecular carriers which carry fragments of DNA into host cell.

More information

Affi-Prep Protein A Matrix Instruction Manual

Affi-Prep Protein A Matrix Instruction Manual Affi-Prep Protein A Matrix Instruction Manual Catalog Numbers 156-0005 156-0006 Bio-Rad Laboratories, 2000 Alfred Nobel Dr., Hercules, CA 94547 LIT-230 Rev B Table of Contents Section 1 Introduction...1

More information

Antibody Purification and Labeling

Antibody Purification and Labeling 5 Antibody Purification and Labeling 5.1 Antibody Purification 65 Magne Protein A Beads and Magne Protein G Beads 67 5.2 Antibody Labeling 69 phab Amine and Thiol Reactive Dyes 71 63 Discover Reliable

More information

Antibody Services. Best Guarantees in the Industry! Monoclonal Antibody Services. Polyclonal Antibody Services. Express Antibody TM Services

Antibody Services. Best Guarantees in the Industry! Monoclonal Antibody Services. Polyclonal Antibody Services. Express Antibody TM Services Antibody Services Best Guarantees in the Industry! Monoclonal Antibody Services Polyclonal Antibody Services Express Antibody TM Services Guaranteed Antibody Services Antibody Purification Services Your

More information

Grundlagen und Anwendung der Genom- und Proteomforschung

Grundlagen und Anwendung der Genom- und Proteomforschung Grundlagen und Anwendung der Genom- und Proteomforschung Profilmodul (Vorlesung/Seminar WS 2012/13) Philipps-Universität Marburg Fachbereich Biologie Professor Dr. Egon Amann & Dr. Frank Vitzthum Gastbeiträge

More information

Custom Polyclonal Anti-Peptide Antibody, Brochure

Custom Polyclonal Anti-Peptide Antibody, Brochure Custom Polyclonal Anti-Peptide Antibody, Brochure Interest in any of the products, request or order them at Bio-Connect. Bio-Connect B.V. T NL +31 (0)26 326 44 50 T BE +32 (0)2 503 03 48 Begonialaan 3a

More information

COMPANY INTRODUCTION. www.cusabio.com

COMPANY INTRODUCTION. www.cusabio.com www.cusabio.com COMPANY INTRODUCTION CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit, in vitro diagnostic raw material,

More information

Optimal Conditions for F(ab ) 2 Antibody Fragment Production from Mouse IgG2a

Optimal Conditions for F(ab ) 2 Antibody Fragment Production from Mouse IgG2a Optimal Conditions for F(ab ) 2 Antibody Fragment Production from Mouse IgG2a Ryan S. Stowers, 1 Jacqueline A. Callihan, 2 James D. Bryers 2 1 Department of Bioengineering, Clemson University, Clemson,

More information

The immune response Antibodies Antigens Epitopes (antigenic determinants) the part of a protein antigen recognized by an antibody Haptens small

The immune response Antibodies Antigens Epitopes (antigenic determinants) the part of a protein antigen recognized by an antibody Haptens small The immune response Antibodies Antigens Epitopes (antigenic determinants) the part of a protein antigen recognized by an antibody Haptens small molecules that can elicit an immune response when linked

More information

Your Partner in Antibody Development. Product and Service Catalog

Your Partner in Antibody Development. Product and Service Catalog Your Partner in Antibody Development Product and Service Catalog ABOUT US QUALITY ASSURANCE Maine Biotechnology Services, Inc. (MBS) is an industry leader in antibody discovery, development and production.

More information

1. Vaccinations. What is Vaccination? Chapter 18: Applications of Immunology. 1. Vaccinations. 2. Monoclonal vs Polyclonal Ab 3. Diagnostic Immunology

1. Vaccinations. What is Vaccination? Chapter 18: Applications of Immunology. 1. Vaccinations. 2. Monoclonal vs Polyclonal Ab 3. Diagnostic Immunology Chapter 18: Applications of Immunology 1. Vaccinations 2. Monoclonal vs Polyclonal Ab 3. Diagnostic Immunology 1. Vaccinations What is Vaccination? A method of inducing artificial immunity by exposing

More information

Isogenica Ltd. Biologics discovery overview

Isogenica Ltd. Biologics discovery overview Isogenica Ltd Biologics discovery overview 1 Isogenica Specialist antibody and peptide display company Based in Cambridge at the heart of UK Biotech Expertise in protein and peptide engineering since 2001

More information

GFP Antibodies. Make Your World More Colorful. Products. III. Wide Applications. Ordering Information

GFP Antibodies. Make Your World More Colorful. Products. III. Wide Applications.  Ordering Information Products III. Wide Applications As the first isolated fluorescent protein, the GFP is frequently used as a reporter gene of expression in cell and molecular biology. So, anti-gfp antibodies have became

More information

Guidance for Industry. Monoclonal Antibodies Used as Reagents in Drug Manufacturing

Guidance for Industry. Monoclonal Antibodies Used as Reagents in Drug Manufacturing Guidance for Industry Monoclonal Antibodies Used as Reagents in Drug Manufacturing U.S. Department of Health and Human Services Food and Drug Administration enter for Drug Evaluation and Research (DER)

More information

Definition of the Measurand: CRP

Definition of the Measurand: CRP A Reference Measurement System for C-reactive Protein David M. Bunk, Ph.D. Chemical Science and Technology Laboratory National Institute of Standards and Technology Definition of the Measurand: Human C-reactive

More information

biomapping FLAG Epitope System Original & Proven System for Demanding Applications

biomapping FLAG Epitope System Original & Proven System for Demanding Applications biomapping FLAG Epitope System Original & Proven System for Demanding Applications biomapping FLAG Epitope System Original & Proven System for Demanding Applications Overview A Proven System for Detection

More information

CHAPTER 6 ANTIBODY GENETICS: ISOTYPES, ALLOTYPES, IDIOTYPES

CHAPTER 6 ANTIBODY GENETICS: ISOTYPES, ALLOTYPES, IDIOTYPES CHAPTER 6 ANTIBODY GENETICS: ISOTYPES, ALLOTYPES, IDIOTYPES See APPENDIX: (3) OUCHTERLONY; (4) AFFINITY CHROMATOGRAPHY Human immunoglobulins are made up of LIGHT and HEAVY chains encoded by a total of

More information

Product Catalogue. Products for Researchers. Antibodies. Antigens. Clinical Specimens. Manufacturing Reagents. Specialist Immunologicals

Product Catalogue. Products for Researchers. Antibodies. Antigens. Clinical Specimens. Manufacturing Reagents. Specialist Immunologicals Product Catalogue Products for Researchers Antibodies Antigens Clinical Specimens Manufacturing Reagents Specialist Immunologicals Binding Site Binding Site is a Specialist Protein company committed to

More information

POLYCLONAL ANTIBODY DEVELOPMENT

POLYCLONAL ANTIBODY DEVELOPMENT POLYCLONAL ANTIBODY DEVELOPMENT Abcore is committed to excellence, and to responding to the changing needs of our customers. We have developed polyclonal antibodies for biotechnology and pharmaceutical

More information

QED Bioscience Inc. Revision 05/04/11 ADVANCED ANTIBODY TECHNOLOGIES

QED Bioscience Inc. Revision 05/04/11 ADVANCED ANTIBODY TECHNOLOGIES CUSTOM POLYCLONAL ANTIBODY DEVELOPMENT QED is committed to excellence across all facets of our operations, and to responding to the ever-changing needs of our customers. We have been developing monoclonal

More information

Shop! VWRBiosciences,more than just a helping hand

Shop! VWRBiosciences,more than just a helping hand section line 2 BioSciences section line 1 VWRBiosciences,more than just a helping hand Proteomics round-up What can we offer? In today s world of discovery, technology is critical to a better understanding

More information

Bispecific antibodies with native chain structure

Bispecific antibodies with native chain structure Bispecific antibodies with native chain structure 11.03.2014 Kristin Fritsch Natural function of antibodies I. Spasevska, Biosciences Master Reviews, 2014 IgG Antibody http://www.ebioscience.com/knowledge-center/antigen/immunoglobulin/structure.htm

More information

Guidance for Industry

Guidance for Industry Guidance for Industry Interpreting Sameness of Monoclonal Antibody Products Under the Orphan Drug Regulations U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation

More information

27E10: A unique monoclonal antibody against MRP8/14 (S100A8/A9, Calprotectin)

27E10: A unique monoclonal antibody against MRP8/14 (S100A8/A9, Calprotectin) BMA BIOMEDICALS Rheinstrasse 28-32 CH-4302 Augst (Switzerland) Phone:+41 61 811 6222 Fax: +41 61 811 6006 info@bma.ch www.bma.ch 27E10: A unique monoclonal antibody against MRP8/14 (S100A8/A9, Calprotectin)

More information

Predict Reactivity Note Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%), Guinea pig (100%)

Predict Reactivity Note Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%), Guinea pig (100%) Datasheet GeneTex, Inc : Toll Free 1-877-GeneTex (1-877-436-3839) Fax:1-949-309-2888 info@genetex.com GeneTex International Corporation : Tel:886-3-6208988 Fax:886-3-6208989 infoasia@genetex.com Date :

More information

Table of Contents GENERAL QUESTIONS. 1. What is the SNAP-tag? 2. How does it work?

Table of Contents GENERAL QUESTIONS. 1. What is the SNAP-tag? 2. How does it work? Table of Contents GENERAL QUESTIONS 1. What is the SNAP-tag? 2. How does it work? 3. How does SNAP-tag labeling differ from using GFP fusion proteins? CLONING AND EXPRESSION 4. What linker type and length

More information

GenScript Antibody Services

GenScript Antibody Services GenScript Antibody Services Scientific experts, innovative technologies, proven performance We specialize in custom antibody production to empower your research Custom Polyclonal Antibody Production Custom

More information

Antibodies Newsflash May 2015

Antibodies Newsflash May 2015 Antibodies Newsflash May 2015 New Antibody Data Troponin I Data CEA Pairing Data PBP2a Data Capabilities Monoclonal antibodies Polyclonal antibodies Recombinant Fab antibodies Quality Partnership Results

More information

Mix-N-Go Protein A Assays

Mix-N-Go Protein A Assays Mix-N-Go Protein A Assays Immunoenzymetric Assays for the Measurement of Protein A Catalog # F600 and Catalog # F610 Intended Use These kits are intended for use in quantitating natural recombinant Protein

More information

Antibody Services from GenScript

Antibody Services from GenScript Services from GenScript www.genscript.com GenScript USA Inc. 860 Centennial Ave., Piscataway, NJ 08854 USA Toll-Free: 1-877-436-7274 Fax: 1-732-210-0262 1-732-885-5878 Academic Services Pharmaceutical

More information

Exclusive customized epigenetic antibodies

Exclusive customized epigenetic antibodies Exclusive customized epigenetic antibodies For many years, Diagenode has acquired a strong and reliable experience in the production of custom epigenetic antibodies, allowing us to become one of the most

More information

Antibodies. Thomas Boenisch, MS, and Jim Hudson, PhD

Antibodies. Thomas Boenisch, MS, and Jim Hudson, PhD Thomas Boenisch, MS, and Jim Hudson, PhD Immunoglobulins The vertebrate immune system has the amazing ability to create millions of different antibodies with different specificities. It is their ability

More information

Medical & Business Solutions

Medical & Business Solutions Medical & Business Solutions SELEGNOSTIC SENSITIVE QUICK INNOVATIVE SIMPLE PRECISE Cardiology Infectious Disease Internal Medicine Gynaecology Drugs CARDIOLOGY D-Dimer Test Cardiac Combo Marker Test Semi-quantitative

More information

Genetics Faculty of Agriculture and Veterinary Medicine

Genetics Faculty of Agriculture and Veterinary Medicine Genetics 10201232 Faculty of Agriculture and Veterinary Medicine Instructor: Dr. Jihad Abdallah Topic 15:Recombinant DNA Technology 1 Recombinant DNA Technology Recombinant DNA Technology is the use of

More information

Anti-Lemon sole (Microstomus kitt) IgM monoclonal antibody. Product no: F24

Anti-Lemon sole (Microstomus kitt) IgM monoclonal antibody. Product no: F24 Anti-Lemon sole (Microstomus kitt) IgM monoclonal antibody Product no: F24 Product Description This monoclonal antibody (Mab) reacts with Lemon sole (Microstomus kitt) immunoglobulin M (IgM). The Mab is

More information

Molecular Cloning, Product Brochure

Molecular Cloning, Product Brochure , Product Brochure Interest in any of the products, request or order them at Bio-Connect. Bio-Connect B.V. T NL +31 (0)26 326 44 50 T BE +32 (0)2 503 03 48 Begonialaan 3a F NL +31 (0)26 326 44 51 F BE

More information

Antibody Production Price List

Antibody Production Price List Antibody Production Price List Presenting Insight Biotechnology s price list for custom polyclonal and monoclonal antibody production services. We are happy to tailor individual packages towards the specific

More information

Anti-ATF6 α antibody, mouse monoclonal (1-7)

Anti-ATF6 α antibody, mouse monoclonal (1-7) Anti-ATF6 α antibody, mouse monoclonal (1-7) 73-500 50 ug ATF6 (activating transcription factor 6) is an endoplasmic reticulum (ER) membrane-bound transcription factor activated in response to ER stress.

More information

Some terms: An antigen is a molecule or pathogen capable of eliciting an immune response

Some terms: An antigen is a molecule or pathogen capable of eliciting an immune response Overview of the immune system We continue our discussion of protein structure by considering the structure of antibodies. All organisms are continually subject to attack by microorganisms and viruses.

More information

Catalogue 2009/2010. Immunological and biochemical services

Catalogue 2009/2010. Immunological and biochemical services Catalogue 2009/2010 Immunological and biochemical services 1 Customised Services Page Antisera and Polyclonal Antibodies 4 Guarantee offer - Rabbit antibodies with guaranteed quality 5 Inclusive offers

More information

Production and purification of monoclonal and polyclonal antibodies. Human S100A8,

Production and purification of monoclonal and polyclonal antibodies. Human S100A8, Supplementary Data Methods Production and purification of monoclonal and polyclonal antibodies. Human SA8, SA9 and SA mouse monoclonal antibodies (mab) were generated using the ClonaCell H hybridoma cloning

More information

TECHNICAL BULLETIN. FluoroTag FITC Conjugation Kit. Product Number FITC1 Storage Temperature 2 8 C

TECHNICAL BULLETIN. FluoroTag FITC Conjugation Kit. Product Number FITC1 Storage Temperature 2 8 C FluoroTag FITC Conjugation Kit Product Number FITC1 Storage Temperature 2 8 C TECHNICAL BULLETIN Product Description The FluoroTag FITC Conjugation Kit is suitable for the conjugation of polyclonal and

More information

Introduction to Bioprocessing

Introduction to Bioprocessing Introduction to Bioprocessing Cambridge Healthtech Institute Peptalk Palm Springs, CA Presented by Susan Dana Jones and Sheila Magil BioProcess Technology Consultants www.bptc.com BioProcess Technology

More information

Aviva Systems Biology

Aviva Systems Biology Aviva Custom Antibody Services and Prices Rabbit Polyclonal Antibody Service Package Number Description Package Contents Time Price Polyclonal package 1 (From protein to antiserum) Polyclonal package 2

More information

CHAPTER 8 IMMUNOLOGICAL IMPLICATIONS OF PEPTIDE CARBOHYDRATE MIMICRY

CHAPTER 8 IMMUNOLOGICAL IMPLICATIONS OF PEPTIDE CARBOHYDRATE MIMICRY CHAPTER 8 IMMUNOLOGICAL IMPLICATIONS OF PEPTIDE CARBOHYDRATE MIMICRY Immunological Implications of Peptide-Carbohydrate Mimicry 8.1 Introduction The two chemically dissimilar molecules, a peptide (12mer)

More information

High-speed quantitation or purification

High-speed quantitation or purification PRODUCT BULLETIN POROS Affinity Chromatography Columns POROS Affinity Chromatography Columns High-speed quantitation or purification Broad utility POROS A, G, and CaptureSelect affinity ligands address

More information

Mouse Typer Sub-Isotyping Kit Instruction Manual

Mouse Typer Sub-Isotyping Kit Instruction Manual Mouse Typer Sub-Isotyping Kit Instruction Manual Protocol for Mouse Typer Sub-Isotyping Kit (Catalog Number 172-2051) and Mouse Typer Sub Isotyping Panel (Catalog Number 172-2055) For Technical Service

More information

Bio-Reagents Gene synthesis Peptide Synthesis Protein Expression Antibody Production. Life Science Products and Services

Bio-Reagents Gene synthesis Peptide Synthesis Protein Expression Antibody Production. Life Science Products and Services Bio-Reagents Gene synthesis Peptide Synthesis Protein Expression Antibody Production Life Science Products and Services Since 2002, Biomatik has provided worldwide researchers in life science discovery

More information

Understanding secondary antibodies

Understanding secondary antibodies Understanding secondary antibodies IgG Fragment antigen binding antibodies and isotypes D2 D2 F(ab ) 2 after pepsin cleavage www.abcam.com/secondary_antibody Antibody structure and F(ab) antibodies The

More information

Chapter 6. Antigen-Antibody Properties 10/3/2012. Antigen-Antibody Interactions: Principles and Applications. Precipitin reactions

Chapter 6. Antigen-Antibody Properties 10/3/2012. Antigen-Antibody Interactions: Principles and Applications. Precipitin reactions Chapter 6 Antigen-Antibody Interactions: Principles and Applications Antigen-Antibody Properties You must remember antibody affinity (single) VS avidity (multiple) High affinity: bound tightly and longer!

More information

Methodological considerations: Potency tests for recombinant adjuvanted RTS,S vaccine

Methodological considerations: Potency tests for recombinant adjuvanted RTS,S vaccine Methodological considerations: Potency tests for recombinant adjuvanted RTS,S vaccine Background Adjuvanted recombinant RTS,S-based vaccines have been in clinical evaluation since the late 1980s and various

More information

GenScript Antibody Services

GenScript Antibody Services GenScript Antibody Services Scientific experts, innovative technologies, proven performance We specialize in custom antibody production to empower your research Custom Polyclonal Antibody Production Custom

More information