Grigoriu B, Scherpereel A. Screening for malignant mesothelioma--looking for the holy grail. Am J Respir Crit Care Med, 2009, 179:851.

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1 LES PUBLICATIONS MOLECULAR PULMONARY IMMUNITY Inserm U CNRS UMR 8204 University Lille 1 - University Lille 2 Institut Pasteur de Lille affiliated to IFR 142 Responsable Anne TSICOPOULOS 2010 Barlési F, Balleyguier C, Besse B, Bonodeau F, Brenac F, Corneloup O, Dansin E, Ferretti G, Gaubert JY, Gervais R, Lacombe C, Loundou A, Moro-Sibilot D, Planchard D, Scherpereel A, Menu Y. Inter- and intraobserver consistency in assessing eligibility for bevacizumab (BVZ) in non-small-cell lung cancer (NSCLC) patients with centrally located tumors. Ann Oncol, 2010 Jan 11. [Epub ahead of print] Burgel PR, Paillasseur JL, Caillaud D, Tillie-Leblond I, Chanez P, Escamilla R, Court-Fortune I, Perez T, Carré P, Roche N ; on behalf of the Initiatives BPCO Scientific Committee. Clinical COPD phenotypes : a novel approach using principal component and cluster analyses. Eur Respir J, 2010 Jan 14. [Epub ahead of print] Chang Y, de Nadai P, Azzaoui I, Morales O, Delhem N, Vorng H, Tomavo S, Ait Yahia S, Zhang G, Wallaert B, Chenivesse C, Tsicopoulos A. The chemokine CCL18 generates adaptive regulatory T cells from memory CD4+ T cells of healthy but not allergic subjects. FASEB J, 2010, Aug 11. [Epub ahead of print] Deswarte G, Richardson M, Polge AS, Pouwels S, Ennezat PV, Trochu JN, Wallaert B, Deklunder G, Le Tourneau T. Longitudinal Right Ventricular Function as a Predictor of Functional Capacity in Patients with Mitral Stenosis : An Exercise Echocardiographic Study. J Am Soc Echocardiogr, 2010 Apr 29. [Epub ahead of print]. Just N, Bautin N, Danel-Brunaud V, Debroucker V, Matran R, Perez T. The BORG dyspnoea score : a relevant clinical marker of inspiratory muscle weakness in amyotrophic lateral sclerosis. Eur Respir J, 2010, 35: Leroy X, Aubert S, Zini L, Franquet H, Kervoaze G, Villers A, Delehedde M, Copin MC, Lassalle P. Vascular endocan (ESM-1) is markedly overexpressed in clear cell renal cell carcinoma. Histopathology, 2010, 56: Morawiec E, Hachulla-Lemaire AL, Chabrol J, Rémy-Jardin M, Wallaert B. Venoatrial compression by lymphadenopathy in sarcoidosis. Eur Respir J, 2010, 35: Mouillot G, Carmagnat M, Gérard L, Garnier JL, Fieschi C, Vince N, Karlin L, Viallard JF, Jaussaud R, Boileau J, Donadieu J, Gardembas M, Schleinitz N, Suarez F, Hachulla E, Delavigne K, Morisset M, Jacquot S, Just N, Galicier L, Charron D, Debré P, Oksenhendler E, Rabian C for the DEFI Study Group. B-Cell and T-Cell Phenotypes in CVID Patients Correlate with the Clinical Phenotype of the Disease. J Clin Immunol, 2010, 30: Paesmans M, Berghmans T, Dusart M, Garcia C, Hossein-Foucher C, Lafitte JJ, Mascaux C, Meert AP, Roelandts M, Scherpereel A, Terrones Munoz V, Sculier JP; European Lung Cancer Working Party, and on behalf of the IASLC Lung Cancer Staging Project. Primary tumor standardized uptake value measured on fluorodeoxyglucose positron emission tomography is of prognostic value for survival in non-small cell lung cancer : update of a systematic review and meta-analysis by the European Lung Cancer Working Party for the International Association for the Study of Lung Cancer Staging Project. J Thorac Oncol, 2010, 5:

2 Pourcet B, Pineda-Torra I, Derudas B, Staels B, Glineur C. SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR. J Biol Chem, 2010, 285(9): Raiko I, Sander I, Weber DG, Raulf-Heimsoth M, Gillissen A, Kollmeier J, Scherpereel A, Brüning T, Johnen G. Development of an enzyme-linked immunosorbent assay for the detection of human calretinin in plasma and serum of mesothelioma patients. BMC Cancer, 2010, 10:242. Reikvam H, Hatfield KJ, Lassalle P, Kittang AO, Ersvaer E, Bruserud Ø. Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells : studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release. Expert Opin Investig Drugs, 2010, 19: Sarrazin S, Lyon M, Deakin JA, Guerrini M, Lassalle P, Delehedde M, Lortat-Jacob H. Characterization and binding activity of the chondroitin / dermatan sulphate chain from Endocan, a soluble endothelial Proteoglycan. Glycobiology, 2010, Jun 24. [Epub ahead of print]. Scherpereel A, Astoul P, Baas P, Berghmans T, Clayson H, de Vuyst P, Dienemann H, Galateau-Salle F, Hennequin C, Hillerdal G, Le Péchoux C, Mutti L, Pairon JC, Stahel R, van Houtte P, van Meerbeeck J, Waller D, Weder W. Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for management of Malignant Pleural Mesothelioma. Eur Respir J, 2009 Aug 28. [Epub ahead of print] Scherpereel A, Berghmans T, Lafitte JJ, Colinet B, Richez M, Bonduelle Y, Meert AP, Dhalluin X, Leclercq N, Paesmans M, Willems L; J.P. Sculier for the European Lung Cancer Working Party (ELCWP). Valproate-doxorubicin : promising therapy for progressing mesothelioma. A phase II study. Eur Respir J, 2010, Jun 7.[Epub ahead of print] Tillie-Leblond I, Grenouillet F, Reboux G, Roussel S, Chouraki B, Lorthois C, Dalphin JC, Wallaert B, Millon L. Hypersensitivity pneumonitis and metalworking fluids contaminated by Mycobacteria. Eur Respir J, 2010, Aug 6. Torres D, Dieudonné A, Ryffel B, Vilain E, Si-Tahar M, Pichavant M, Lassalle P, Trottein F, Gosset P. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. J Immunol, 2010, 185: Van Meerbeeck JP, Scherpereel A, Surmont VF, Baas P. Malignant pleural mesothelioma : The standard of care and challenges for future management. Crit Rev Oncol Hematol, 2010, May 11. [Epub ahead of print] Behr J, Demedts M, Buhl R, Costabel U, Dekhuijzen RP, Jansen HM, MacNee W, Thomeer M, Wallaert B, Laurent F, Nicholson AG, Verbeken EK, Verschakelen J, Flower CD, Petruzzelli S, De Vuyst P, van den Bosch JM, Rodriguez-Becerra E, Lankhorst I, Sardina M, Boissard G ; IFIGENIA study group. Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial. Respir Res, 2009, 10:101. Estrella C, Rocks N, Paulissen G, Quesada-Calvo F, Noël A, Vilain E, Lassalle P, Tillie-Leblond I, Cataldo D, Gosset P. Role of A disintegrin and metalloprotease-12 in neutrophil recruitment induced by airway epithelium. Am J Respir Cell Mol Biol, 2009, 41: Gilet J, Chang Ying, Chenivesse C, Legendre B, Vorng H, Duez C, Wallaert B, Porte H, Senechal S, Tsicopoulos A. Role of CCL17 in the generation of cutaneous inflammatory reactions in hu-pbmc-scid mice grafted with human skin. J Invest Dermatol, 2009, 129:

3 Grigoriu B, Chahine B, Zerimech F, Grégoire M, Balduyck M, Copin MC, Devos P, Lassalle P, Scherpereel A. Serum mesothelin has a higher diagnostic utility than hyaluronic acid in malignant mesothelioma. Clin Biochem, 2009, 42: Grigoriu BD, Grigoriu C, Chahine B, Gey T, Scherpereel A. Clinical utility of diagnostic markers for malignant pleural mesothelioma. Monaldi Arch Chest Dis, 2009, 71: Grigoriu B, Scherpereel A. Screening for malignant mesothelioma--looking for the holy grail. Am J Respir Crit Care Med, 2009, 179:851. Hatfield K, Øyan AM, Ersvaer E, Kalland KH, Lassalle P, Gjertsen BT, Bruserud Ø. Primary human acute myeloid leukaemia cells increase the proliferation of microvascular endothelial cells through the release of soluble mediators. Br J Haematol, 2009, 144: Grigoriu BD, Chahine B, Vachani A, Gey T, Conti M, Sterman DH, Marchandise G, Porte H, Albelda SM, Scherpereel A. Kinetics of soluble mesothelin in patients with malignant pleural mesothelioma during treatment. Am J Respir Crit Care Med, 2009, 179: Holmberg K, Tonnel AB, Dreyfus I, Olsson P, Cougnard J, Mesbah K, Devillier P. Desloratadine relieves nasal congestion and improves quality-of-life in persistent allergic rhinitis. Allergy, 2009, 64: Hubert D, Le Roux E, Lavrut T, Wallaert B, Scheid P, Manach D, Grenet D, Sermet-Gaudelus I, Ramel S, Cracowski C, Sardet A, Wizla N, Deneuville E, Garraffo R. Continuous versus intermittent infusions of ceftazidime for treating exacerbation of cystic fibrosis. Antimicrob Agents Chemother, 2009, 53: King TE Jr, Albera C, Bradford WZ, Costabel U, Hormel P, Lancaster L, Noble PW, Sahn SA, Szwarcberg J, Thomeer M, Valeyre D, du Bois RM ; Wallaert B for the INSPIRE Study Group. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE) : a multicentre, randomised, placebocontrolled trial. Lancet, 2009, 374: Maurage CA, Adam E, Minéo JF, Sarrazin S, Debunne M, Siminski RM, Baroncini M, Lassalle P, Blond S, Delehedde M. Endocan expression and localization in human glioblastomas. J Neuropathol Exp Neurol, 2009, 68: Moreau C, Gosset P, Brunaud-Danel V, Lassalle P, Degonne B, Destee A, Defebvre L, Devos D. CSF profiles of angiogenic and inflammatory factors depend on the respiratory status of ALS patients. Amyotroph Lateral Scler, 2009, 10: Perez T, Arnould B, Grosbois JM, Bosch V, Guillemin I, Bravo ML, Brun M, Tonnel AB; TIPHON Study Group. Validity, reliability, and responsiveness of a new short Visual Simplified Respiratory Questionnaire (VSRQ) for healthrelated quality of life assessment in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis, 2009, 4:9-18. Ryningen A, Stapnes C, Lassalle P, Corbascio M, Gjertsen BT, Bruserud O. A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid. Leuk Res, 2009, 3: Roux AL, Catherinot E, Ripoll F, Soismier N, Macheras E, Ravilly S, Bellis G, Vibet MA, Le Roux E, Lemonnier L, Gutierrez C, Vincent V, Fauroux B, Rottman M, Guillemot D, Gaillard JL, Herrmann JL, Wallaert B for the OMA Group. Multicenter study of prevalence of nontuberculous mycobacteria in patients with cystic fibrosis in france. J Clin Microbiol, 2009, 47:

4 Taront S, Dieudonné A, Blanchard S, Jeannin P, Lassalle P, Delneste Y, Gosset P. Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells. Part Fibre Toxicol, 2009, 6:9. Vandermeers F, Hubert P, Delvenne P, Mascaux C, Grigoriu B, Burny A, Scherpereel A, Willems L. Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. Clin Cancer Res, 2009, 15: Adam E, Sarrazin S, Landolfi C, Motte V, Lortat-Jacob H, Lassalle P, Delehedde M. Efficient long-term and high-yielded production of a recombinant proteoglycan in eukaryotic HEK293 cells using a membrane-based bioreactor. Biochem Biophys Res Commun, 2008, 369: Berghmans T, Dusart M, Paesmans M, Hossein-Foucher C, Buvat I, Castaigne C, Scherpereel A, Mascaux C, Moreau M, Roelandts M, Alard S, Meert AP, Patz EF Jr, Lafitte JJ, Sculier JP; European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project. Primary tumor standardized uptake value (SUVmax) measured on fluorodeoxyglucose positron emission tomography (FDG-PET) is of prognostic value for survival in nonsmall cell lung cancer (NSCLC) : a systematic review and meta-analysis (MA) by the European Lung Cancer Working Party for the IASLC Lung Cancer Staging Project. J Thorac Oncol, 2008, 3:6-12. Berghmans T, Gourcerol D, Lafitte JJ, Kotsori K, Paesmans M, Scherpereel A, Leclercq N, Sculier JP; for the European Lung Cancer Working Party. Mitomycin plus vinorelbine salvage chemotherapy in non-small cell lung cancer : a prospective study. Lung Cancer, 2008, 61: Carré PC, Roche N, Neukirch F, Radeau T, Perez T, Terrioux P, Ostinelli J, Pouchain D, Huchon G. The Effect of an Information Leaflet upon Knowledge and Awareness of COPD in Potential Sufferers. A Randomized Controlled Study. Respiration, 2008, 76: Catlow KR, Deakin JA, Wei Z, Delehedde M, Fernig DG, Gherardi E, Gallagher JT, Pavão MS, Lyon M. Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density. J Biol Chem, 2008, 283: Depontieu F, Grigoriu BD, Scherpereel A, Adam E, Delehedde M, Gosset P, Lassalle P. Loss of Endocan tumorigenic properties after alternative splicing of exon 2. BMC Cancer, 2008, 8:14. Ferrari F, Liu ZH, Lu Q, Becquemin MH, Louchahi K, Aymard G, Marquette CH, Rouby JJ. Comparison of lung tissue concentrations of nebulized ceftazidime in ventilated piglets: ultrasonic versus vibrating plate nebulizers. Intensive Care Med, Grigoriu BD, Scherpereel A. Diagnostic value of soluble mesothelin in malignant mesothelioma. Thorax, 2008, 63: Plé C, Duez C. Toll-like receptor expressing cells for antiallergy compound screening. Expert Opinion on drug Discovery, 2008, 3: Revel MP, Faivre JB, Remy-Jardin M, Deken V, Duhamel A, Marquette CH, Tacelli N, Bakai AM, Remy J. Automated lobar quantification of emphysema in patients with severe COPD. Eur Radiol, Roche N, Dalmay F, Perez T, Kuntz C, Vergnenègre A, Neukirch F, Giordanella JP, Huchon G. Impact of chronic airflow obstruction in a working population. Eur Respir J, 2008, 31:

5 Sapede C, Gauvrit A, Barbieux I, Padieu M, Cellerin L, Sagan C, Scherpereel A, Dabouis G, Grégoire M. Aberrant splicing and protease involvement in mesothelin release from epithelioid mesothelioma cells. Cancer Sci, 2008, 99: Tillie-Leblond I, Wislez M, Valeyre D, Crestani B, Rabbat A, Israel-Biet D, Humbert M, Couderc LJ, Wallaert B, Cadranel J. Interstitial lung disease and anti-jo-1 antibodies : difference between acute and gradual onset. Thorax, 2008, 63: Tsicopoulos A, Duez C, Saxon A. Environmental Factors in IgE production. Allergy and Allergic Diseases (Second Edition). Blackwell publishing, 2008 Chapter 7. Tonnel AB, Pouwels-Frys S, Tillie-Leblond I. Allergic bronchopulmonary aspergillosis. Allergy and Allergic Diseases (Second Edition). Blackwell publishing, 2008 Chapter Amniai L, Biet F, Marquillies P, Locht C, Pestel J, Tonnel AB, Duez C. Does not Increase Allergic Airway Disease in Mice When Produced by BCG. J Biomed Biotechnol, 2007: Berghmans T, Lafitte JJ, Lecomte J, Alexopoulos CG, Van Cutsem O, Giner V, Efremidis A, Berchier MC, Collon T, Meert AP, Scherpereel A, Ninane V, Leclercq N, Paesmans M, Sculier JP ; European Lung Cancer Working Party. Second-line paclitaxel in non-small cell lung cancer initially treated with cisplatin: a study by the European Lung Cancer Working Party. Br J Cancer, 2007, 96: Collet F, Mallart A, Bervar JF, Bautin N, Matran R, Pattou F, Romon M, Perez T. Physiologic correlates of dyspnea in patients with morbid obesity. Int J Obes (Lond), 2007, 31: Conti M, Robin E, Porte H, Marquette CH, Wurtz A. Management of postintubation tracheobronchial ruptures. Ann Thorac Surg, 2007, 83:1924. Dusser D, Montani D, Chanez P, de Blic J, Delacourt C, Deschildre A, Devillier P, Didier A, Leroyer C, Marguet C, Martinat Y, Piquet J, Raherison C, Serrier P, Tillie-Leblond I, Tonnel AB, Tunon de Lara M, Humbert M. Mild asthma: an expert review on epidemiology, clinical characteristics and treatment recommendations. Allergy, 2007, 62: Freitag L, Ernst A, Unger M, Kovitz K, Marquette CH. A proposed classification system of central airway stenosis. Eur Respir J, 2007, 30:7-12. Greillier L, Cavailles A, Fraticelli A, Scherpereel A, Barlesi F, Tassi G, Thomas P, Astoul P. Accuracy of pleural biopsy using thoracoscopy for the diagnosis of histologic subtype in patients with malignant pleural mesothelioma. Cancer, 2007, 110(10): Grigoriu BD, Scherpereel A, Devos P, Chahine B, Letourneux M, Lebailly P, Grégoire M, Porte H, Copin MC, Lassalle P. Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment. Clin Cancer Res, 2007, 13: Janssen JP, Collier G, Astoul P, Tassi GF, Noppen M, Rodriguez- Panadero F, Loddenkemper R, Herth FJ, Gasparini S, Marquette CH, Becke B, Froudarakis ME, Driesen P, Bolliger CT, Tschopp JM. Safety of pleurodesis with talc poudrage in malignant pleural effusion : a prospective cohort study. Lancet, 2007, 369:

6 Just N, Moreau C, Lassalle P, Gosset P, Perez T, Brunaud-Danel V, Wallaert B, Destée A, Defebvre L, Tonnel AB, Devos D. High erythropoietin and low vascular endothelial growth factor levels in cerebrospinal fluid from hypoxemic ALS patients suggest an abnormal response to hypoxia. Neuromuscul Disord, 2007, 17: Makris D, Hatthabi M, Scherpereel A, Lafitte JJ, Marquette CH. Haemothorax after pig-tail catheter removal in a patient with primary spontaneous pneumothorax. Emerg Med J, 2007, 24:e17. Makris D, Marquette CH. Tracheobronchial stenting and central airway replacement. Curr Opin Pulm Med, 2007, 13: Makris D, Scherpereel A, Copin MC, Colin G, Brun L, Lafitte JJ, Marquette CH. Fatal interstitial lung disease associated with oral erlotinib therapy for lung cancer. BMC Cancer, 2007, 7:150. Makris D, Scherpereel A, Leroy S, Bouchindhomme B, Faivre JB, Remy J, Ramon P, Marquette CH. Electromagnetic navigation diagnostic bronchoscopy for small peripheral lung lesions. Eur Respir J, 2007, 29: Nseir S, Duguet A, Copin MC, De Jonckheere J, Zhang M, Similowski T, Marquette CH. Continuous control of endotracheal cuff pressure and tracheal wall damage: a randomized controlled animal study. Crit Care, 2007, 11:R109. Ratajczak C, Duez C, Grangette C, Pochard P, Tonnel AB, Pestel J. Impact of lactic Acid bacteria on dendritic cells from allergic patients in an experimental model of intestinal epithelium. J Biomed Biotechnol, 2007, 2007: Rennel E, Mellberg S, Dimberg A, Petersson L, Botling J, Ameur A, Westholm JO, Komorowski J, Lassalle P, Cross MJ, Gerwins P. Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer. Exp Cell Res, 2007, 313: Scherpereel A ; French Speaking Society for Chest Medicine (SPLF) Experts Group. Guidelines of the French Speaking Society for Chest Medicine for management of malignant pleural mesothelioma. Respir Med, 2007, 101: Scherpereel A, Lee YC. Biomarkers for mesothelioma. Curr Opin Pulm Med, 2007, 13: Sculier JP, Lafitte JJ, Lecomte J, Alexopoulos CG, Van Cutsem O, Giner V, Efremidis A, Berchier MC, Collon T, Meert AP, Scherpereel A, Ninane V, Paesmans M, Berghmans T ; European Lung Cancer Working Party. A phase III randomised trial comparing sequential chemotherapy using cisplatin-based regimen and paclitaxel to cisplatin-based chemotherapy alone in advanced non-small-cell lung cancer. Ann Oncol, 2007, 18: Sculier JP, Lafitte JJ, Paesmans M, Lecomte J, Alexopoulos CG, Van Cutsem O, Giner V, Efremidis A, Berchier MC, Collon T, Meert AP, Scherpereel A, Ninane V, Koumakis G, Vaslamatzis MM, Leclercq N, Berghmans T ; European Lung Cancer Working Party. Chemotherapy improves low performance status lung cancer patients. Eur Respir J, 2007, 30: Shuvaev VV, Christofidou-Solomidou M, Scherpereel A, Simone E, Arguiri E, Tliba S, Pick J, Kennel S, Albelda SM, Muzykantov VR. Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium. J Control Release, 2007, 118: Tillie-Leblond I, Gosset P, Le Berre R, Janin A, Prangère T, Tonnel AB, Guery BP. Keratinocyte growth factor improves alterations of lung perme ability and bronchial epithelium in allergic rats. Eur Respir J, 2007, 30:31-39.

7 Tunon-de-Lara JM, Laurent F, Giraud V, Perez T, Aguilaniu B, Meziane H, Basset-Merle A, Chanez P. Air trapping in mild and moderate asthma: effect of inhaled corticosteroids. J Allergy Clin Immunol, 2007, 119: Vanpouille C, Deligny A, Delehedde M, Denys A, Melchior A, Liénard X, Lyon M, Mazurier J, Fernig DG, Allain F. The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. J Biol Chem, 2007, 282: PhD Coline PLE Directrice de thèse : Catherine Duez Role des cellules NK dans l asthme allergique. Le 2 Avril Benjamin LEGENDRE Directeur de thèse : Philippe Lassalle Etude comparative structurale et fonctionelle de CCL18 recombinant produit par la CHO et E. Coli. Le 10 Mars Nathalie de FREITAS CAIRES Directeur de thèse : Philippe Lassalle Etude de la dégradation d endocan par les neutrophiles et implication dans le sepsis. Le 19 Décembre Jules GILET Directrice de thèse : Anne Tsicopoulos Implication des chimiokines dans le développement des réactions allergiques : apport des modèles murins. Le 18 Décembre Latiffa AMNIAI Directrice de thèse : Catherine Duez Régulation de la réaction allergique pulmonaire : inhibition par un BCG recombinant dans un modèle murin et déficit de la réponse des cellules Natural Killer de patients allergiques à la chimiokine CCL18. Le 17 Décembre Cécile CHENIVESSE Directrice de thèse : Anne Tsicopoulos Les chimiokines, actrices de la déviation immune. Le 11 Décembre 2007 Stéphane SARRAZIN Directrice de thèse : Maryse Delehedde Caractérisation des interactions glycosaminoglycannes/protéines dans le but de développer des molécules d intérêt thérapeutique : exemples de l Endocan et de l'interféron gamma. Le 27 Juin 2007 Patents de Freitas Caires N, Kervoaze G, Marchandise G, Lassalle P. Marker peptides for determining the occurrence of an inflammatory state in a subject Dépôt le 8 octobre EP Lassalle P, Grigoriu BD, Depontieu F, Marchandise G, Kervoaze G, Janin A. The use of a non-glycanated polypeptide for treating a cancer Dépôt le 24 octobre Brevet BIO60226

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