Second European School of Dermato- Fundamentals of cutaneous oncology

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1 Course Directors Prof. Sibel Alper, Istanbul, Turkey Prof. Claus Garbe, Tuebingen, Germany Second European School of Dermato- Oncology, organized by EADO: Fundamentals of cutaneous oncology Final Program Istanbul, Turkey January 16 th 18 th, 2014 Point Hotel Taksim

2 Content EADO European School of Dermato-Oncology 2 Target Audience 2 Educational Objectives 2 Course Organization 3 Program Overview 4 Program 6 Thursday, January 16 th, Friday, January 17 th, Saturday, January 18 th, EADO Dermato-Oncology Committee 11 Course Faculty 11 General Information 12 Sponsors 15 Registration Form

3 2 EADO European School of Dermato-Oncology The EADO is a non-profit organization funded in 1999 to promote, coordinate and improve clinical and laboratory research activities in the field of skin cancer including primary and secondary prevention, early detection, clinical diagnosis and clinical and experimental research. EADO has organized many successful meetings and the upcoming ones are visible on the website (www.eado.org). The EADO initiates for the second time a course dedicated to fundamentals in skin cancer targeted to specialists and residents in the final phase of their resident program. They will benefit a comprehensive and updated course to improve their decision-making process for the management of all types and stages of skin cancer, from diagnosis, primary treatment and adjuvant treatment, to the management of locoregional disease and distant metastatic disease. It is intended to organize this course every year in different countries. Target Audience This 2,5-day educational course targets doctors who are actively involved in the treatment of skin cancer. Dermatologists or other specialists who have completed specialist training, or residents in the final year of their training program, are likely to gain the most from this course. The maximum number of delegates is 100. In order to make the course available throughout Europe, places will be made available on a first come first served basis to all applicants. Educational Objectives The principal aim of the course is to provide a comprehensive and detailed understanding of the decision-making process for the management of all types and stages of skin cancer. This will include diagnosis and primary treatment, management of locoregional disease and distant metastatic disease, and adjuvant treatment. This is particularly relevant given the rapid progress in our understanding of melanoma and non-melanoma skin cancer, and the development of new treatments. In particular delegates will acquire the following knowledge: 1. Strategies for diagnosis of melanoma, Merkel cell and non-melanoma skin cancer including dermoscopy and confocal laser microscopy. 2. The indications, risks and benefits and strategies for mole screening. 3. Diagnosis of skin cancer: how to break bad news. 4. The indications and methods for genetic diagnosis and genetic counseling of skin cancer patients. 5. The present AJCC staging systems and how to stage melanoma, Merkel cell and cutaneous squamous cell carcinoma, and other non-melanoma skin cancers.

4 3 6. The value of imaging and biomarkers for the detection of metastases and disease staging. 7. Adjuvant treatment of skin cancer: radiotherapy; immunotherapy; chemotherapy. 8. New systemic treatments for stage IV melanoma: targeted agents and immunotherapeutics. 9. New treatment options of advanced basal cell carcinoma. 10. New systemic treatments for advanced Merkel cell and squamous cell carcinoma. 11. The characteristics of mucosal and uveal melanomas and their treatment options. 12. Options for topical treatment of epithelial skin cancers. 13. The current classification of cutaneous lymphoma; staging and treatment options for different subtypes of cutaneous lymphoma. 14. Clinical trials in skin cancer: an update. 15. The indications and strategies for supportive treatments including best supportive care. Course Organization The course consists of plenary sessions and interactive outbreak sessions. Plenary sessions will comprise clear structured and up-to-date presentations followed by audience discussion. Voting devices will be used to respond to multiple choice questions. These questions may precede the presentation of the structured knowledge or may be presented at the end in order to test the level of knowledge the audience has gained. The main part of the course consists of 8 interactive sessions, each with no more than 25 attendants. Every participant takes part in each of these sessions which mainly comprise casebased discussion. These will be used to illustrate treatment pathways, how risk and benefit are assessed, and how management decisions are made. Sibel Alper, MD & Claus Garbe, MD Course Directors

5 4 5 Program Overview A commercial exhibition will be held on all days close to the meeting rooms. 8:00 9:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 Thursday January 16 th, 2014 Group I Group II Group III Group IV Lectures: Giza Ballroom Floor 1 Course A+E: Babylon I 1 st Floor Course B+F: Babylon II 1 st Floor Course C+G: Giza Ballroom Floor 1 Course D+H: Fuji I 9 th Floor Welcome Session Lecture 1 J. Malvehy Lecture 2 S. Şahin Break Course A K. Peris Course B C. Garbe Course c A. Stratigos Course D R.Y. Anadolu Break Course B C. Garbe Course C A. Stratigos Course D R.Y. Anadolu Course A K. Peris Friday January 17 th, 2014 Group I Group II Group III Group IV Lecture 3 V. del Marmol Lecture 4 I. Longo Lecture 5 C. Garbe Break Course C A. Stratigos Course D R.Y. Anadolu Course A K. Peris Course B C. Garbe Break Course D R.Y. Anadolu Course A K. Peris Course B C. Garbe Course C A. Stratigos Lunch Lecture 6 H. Pehamberger Lecture 7 E. Stockfleth Break Course E J. Grob Course F A. Hauschild Course G C. Lebbé Course H C. Robert Break Course F A. Hauschild Course G C. Lebbé Course H C. Robert Course E J. Grob Saturday January 18 th, 2014 Group I Course G C. Lebbé Course H C. Robert Group II Group III Course H C. Robert Course E J. Grob Lecture 8 C. Garbe Lecture 9 A. Hauschild Break Course E J. Grob Course F A. Hauschild Break Lecture 10 J. Oláh Lecture 11 J. Becker Lecture 12 N. Ílter Lecture 13 P. Arenberger Lunch Group IV Course F A. Hauschild Course G C. Lebbé

6 6 Program Thursday, January 16 th, :45 14:00 Plenary Session 1: Welcome and course introduction Chairpersons: Claus Garbe and Sibel Alper 14:00 14:30 Lecture 1: Modern diagnostic tools for early detection of melanoma Josep Malvehy, Barcelona, Spain 14:30 15:00 Lecture 2: Dermoscopic melanoma diagnosis Sedef Şahin, Istanbul, Turkey 15:00 15:30 Coffee Break 15:30 16:30 Course A: Oncogenetic diagnosis and mutational screening Ketty Peris, L Aquila, Italy 15:30 16:30 Course B: Tumorbiopsy and sentinel node biopsy Claus Garbe, Tuebingen, Germany 15:30 16:30 Course C: Epithelial skin cancer: topical and medical treatments in early and advanced diseases Alexander Stratigos, Athens, Greece 15:30 16:30 Course D: Dermoscopy case presentations Rana Yavuzer Anadolu, Ankara, Turkey 16:30 17:00 Coffee Break 17:00 18:00 Course B: Tumorbiopsy and sentinel node biopsy Claus Garbe, Tuebingen, Germany 17:00 18:00 Course C: Epithelial skin cancer: topical and medical treatments in early and advanced diseases Alexander Stratigos, Athens, Greece 17:00 18:00 Course D: Dermoscopy case presentations Rana Yavuzer Anadolu, Ankara, Turkey 17:00 18:00 Course A: Oncogenetic diagnosis and mutational screening Ketty Peris, L Aquila, Italy

7 7 Friday, January 17 th, 2014 Plenary Session 2 Chairpersons: Veronique del Marmol and Isabel Longo 08:00 08:30 Lecture 3: Nevus screening and early detection of melanoma Veronique del Marmol, Brussels, Belgium 08:30 09:00 Lecture 4: The current AJCC classification of skin tumors Isabel Longo, Madrid, Spain 09:00 09:30 Lecture 5: Serologic and imaging diagnostics for tumor staging Claus Garbe, Tuebingen, Germany 09:30 10:00 Coffee Break 10:00 11:00 Course C: Epithelial skin cancer: topical and medical treatments in early and advanced diseases Alexander Stratigos, Athens, Greece 10:00 11:00 Course D: Dermoscopy case presentations Rana Yavuzer Anadolu, Ankara, Turkey 10:00 11:00 Course A: Oncogenetic diagnosis and mutational screening Ketty Peris, L Aquila, Italy 10:00 11:00 Course B: Tumorbiopsy and sentinel node biopsy Claus Garbe, Tuebingen, Germany 11:00 11:30 Coffee Break 11:30 12:30 Course D: Dermoscopy case presentations Rana Yavuzer Anadolu, Ankara, Turkey 11:30 12:30 Course A: Oncogenetic diagnosis and mutational screening Ketty Peris, L Aquila, Italy 11:30 12:30 Course B: Tumorbiopsy and sentinel node biopsy Claus Garbe, Tuebingen, Germany 11:30 12:30 Course C: Epithelial skin cancer: topical and medical treatments in early and advanced diseases Alexander Stratigos, Athens, Greece

8 8 12:30 14:00 Lunch Plenary Session 3 Chairpersons: Hubert Pehamberger and Eggert Stockfleth 14:00 14:30 Lecture 6: Treatment algorithms in metastatic melanoma Hubert Pehamberger, Vienna, Austria 14:30 15:00 Lecture 7: Surveillance and management of immunosuppressed patients Eggert Stockfleth, Berlin, Germany 15:00 15:30 Coffee Break 15:30 16:30 Course E: Skin cancer prevention Jean-Jacques Grob, Marseille, France 15:30 16:30 Course F: Adjuvant treatment with classical and pegylated IFN-alpha Axel Hauschild, Kiel, Germany 15:30 16:30 Course G: Vemurafenib and other tyrosine kinase inhibitors Celeste Lebbé, Paris, France 15:30 16:30 Course H: Ipilimumab/PD1 antibodies Caroline Robert, Paris, France 16:30 17:00 Coffee Break 17:00 18:00 Course F: Adjuvant treatment with classical and pegylated IFN-alpha Axel Hauschild, Kiel, Germany 17:00 18:00 Course G: Vemurafenib and other tyrosine kinase inhibitors Celeste Lebbé, Paris, France 17:00 18:00 Course H: Ipilimumab/PD1 antibodies Caroline Robert, Paris, France 17:00 18:00 Course E: Skin cancer prevention Jean-Jacques Grob, Marseille, France

9 9 Saturday, January 18 th, :00 09:00 Course G: Vemurafenib and other tyrosine kinase inhibitors Celeste Lebbé, Paris, France 08:00 09:00 Course H: Ipilimumab/PD1 antibodies Caroline Robert, Paris, France 08:00 09:00 Course E: Skin cancer prevention Jean-Jacques Grob, Marseille, France 08:00 09:00 Course F: Adjuvant treatment with classical and pegylated IFN-alpha Axel Hauschild, Kiel, Germany Plenary Session 4 Chairpersons: Claus Garbe and Axel Hauschild 09:00 09:30 Lecture 8: Oncogenetics and epidemiology of advanced basal cell carcinoma Claus Garbe, Tuebingen, Germany 09:30 10:00 Lecture 9: New treatment options for advanced basal cell carcinoma Axel Hauschild, Kiel, Germany 10:00 10:15 Coffee Break 10:15 11:15 Course H: Ipilimumab/PD1 antibodies Caroline Robert, Paris, France 10:15 11:15 Course E: Skin cancer prevention Jean-Jacques Grob, Marseille, France 10:15 11:15 Course F: Adjuvant treatment with classical and pegylated IFN-alpha Axel Hauschild, Kiel, Germany 10:15 11:15 Course G: Vemurafenib and other tyrosine kinase inhibitors Celeste Lebbé, Paris, France

10 10 11:15 11:30 Coffee Break Plenary Session 5 Chairpersons: Petr Arenberger and Jürgen Becker 11:30 12:00 Lecture 10: Rare cutaneous malignancies Judit Oláh, Szeged, Hungary 12:00 12:30 Lecture 11: Merkel cell carcinoma and dermatofibrosarcoma protuberans Jürgen Becker, Graz, Austria 12:30 13:00 Lecture 12: How to recognize cutaneous lymphomas Nilsel Ílter, Ankara, Turkey 13:00 13:30 Lecture 13: Cutaneous lymphoma treatment Petr Arenberger, Prague, Czech Republic 13:30 14:30 Lunch (with lunch box)

11 11 EADO Dermato-Oncology Committee Sibel Alper, Istanbul, Turkey Claus Garbe, Tuebingen, Germany Judit Oláh, Szeged, Hungary Hubert Pehamberger, Vienna, Austria Course Faculty Sibel Alper, Istanbul, Turkey Petr Arenberger, Prague, Czech Republic Jürgen Becker, Graz, Austria Veronique del Marmol, Brussels, Belgium Claus Garbe, Tuebingen, Germany Jean-Jacques Grob, Marseille, France Axel Hauschild, Kiel, Germany Nilsel Ílter, Ankara, Turkey Celeste Lebbé, Paris, France Isabel Longo, Madrid, Spain Josep Malvehy, Barcelona, Spain Judit Oláh, Szeged, Hungary Hubert Pehamberger, Vienna, Austria Ketty Peris, L Aquila, Italy Caroline Robert, Paris, France Sedef Şahin, Istanbul, Turkey Eggert Stockfleth, Berlin, Germany Alexander Stratigos, Athens, Greece Rana Yavuzer Anadolu, Ankara, Turkey

12 12 General Information Course Venue Point Hotel Taksim Topçu Caddesi No Taksim Istanbul, Turkey Phone: Course Organization MedConcept Gesellschaft für medizinische Projekte mbh Ms. Mirja Christ Friedenstraße Neuenhagen b. Berlin, Germany Phone: +49 (0) Fax: +49 (0) Hotel Accommodation MedConcept has reserved a limited number of rooms at the Point Hotel Taksim. Rate per standard room and night: 120 Euro single/130 Euro double, breakfast included. Booking deadline: December 15, 2013 Reservation after this date will be subject to space and rate availability. For your individual room booking, please follow the instructions given on the course website (www.dermato-oncology2014.org/information/accommodation). Language and Translation The official language of the meeting will be English. Simultaneous translation will not be provided.

13 13 Exhibition A commercial exhibition will be held at the meeting venue, close to the main meeting rooms. If you are interested in participating as an exhibitor, please contact MedConcept s secretariat for further information. Exhibition Opening Hours Thursday, January 16: 13:00 18:30 Friday, January 17: 07:30 18:30 Saturday, January 18: 07:30 14:00 CME Credits An application for CME accreditation will be made. Cancellation Policy Cancellations must be received in writing by December 17 th, No refunds will be granted after that date. A processing fee of 30 Euro will be deducted from each cancelled registration. Substitutions are possible. To substitute a registration please send an including the name of the original registrant and the name of the person substituting to The participant acknowledges that he/she has no right to lodge damage claims against the organizers should the holding of the meeting be hindered or prevented by unexpected, political or economic events or generally by force, or should the nonappearance of speakers or other reasons need program changes. With registration, the participant accepts this proviso.

14 14 Notes

15 15 Sponsors Gold Silver Bronze Further Sponsors Almirall Novartis

16 Amgen is researching ways to help T cells target cancer. Find it T cell Cancer cell Fight it ONCOLYTIC IMMUNOTHERAPY is an innovative area of research that uses a modified virus designed to help T cells find and fight cancer cells as part of a hypothesized systemic, tumor-specific immune response. 1. Reference: 1. Melcher A, Parato K, Rooney CM, Bell JC. Thunder and lightning: immunotherapy and oncolytic viruses collide. Mol Ther 2011;19: Amgen (Europe) GmbH Dammstrasse 23 CH-6300 Zug Switzerland 2013 Amgen Inc. All rights reserved. TVC-IHQ-AMG November-NP Amgen. Leading the way in the study of Oncolytic Immunotherapy. Almirall Dermatology Staying ahead of ACTINIC KERATOSIS

17 Registration Form Second European School of Dermato-Oncology, organized by EADO: Fundamentals of Cutaneous Oncology Istanbul, Turkey, January 16 th 18 th, 2014 First Name: Last Name: Professional Title: Degree: MD PhD RN PA-C Gender: Male Female Speciality: Institution: Address: City: Zip Code: Country: Phone: Fax: Fees Registration Fee of 380,00 Euro (incl. VAT) covers Admission to scientific sessions Admission to exhibition Bag with course documents Welcome reception Coffee breaks and lunch Certificate of Attendance Payment Method Bank Transfer: Registration can only be confirmed upon receipt of full payment. Credit Card: MasterCard Visa American Express Credit Card Number: Expiration Date: Security Code CCV: (MC/Visa 3 digits on back, AMEX 4 digits on front) Layout: MediaService GmbH Druck und Kommunikation Cover picture: istockphoto.com/omergenc, Servet Gürbüz [M] Cardholder Name: Signature: An invoice will be send by mail to the given address. If the invoice address is different from the address given above, please send an including the name of the registrant and the full invoice address to By completing the registration form, the participant accepts the cancellation policy as stated in the course program. To Register Mail registration form to: MedConcept GmbH, Friedenstraße Neuenhagen bei Berlin, Germany Fax registration form to: +49 (0) Register online: Printed on 100 % recycled paper

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