1. IDENTIFICATION. US IVD HCCA, portioned BD Bruker US IVD HCCA, Portioned

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1 Safety Data Sheet Issue Date: 26-Nov-2013 Revision Date: 01-Jan-2015 Version B Product Identifier Product Name Other means of identification SDS # Other Information 1. IDENTIFICATION US IVD HCCA, portioned BD Bruker US IVD HCCA, Portioned Recommended use of the chemical and restrictions on use Recommended Use Laboratory chemicals. Details of the supplier of the safety data sheet Supplier Address Bruker Daltonics 40 Manning Road Billerica, MA IVD HCCA-PN Catalog Number: US IVD HCCA PN BD Bruker US IVD HCCA- PN Emergency Telephone Number Company Phone Number Emergency Telephone (24 hr) INFOTRAC (International) (North America) 2. HAZARDS IDENTIFICATION Appearance Light yellow powder Physical State Solid Odor Characteristic Classification Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 2A Specific target organ toxicity (single exposure) Category 3 Signal Word Warning Hazard Statements Causes skin irritation Causes serious eye irritation May cause respiratory irritation. May cause drowsiness or dizziness Precautionary Statements - Prevention Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection Avoid breathing dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Page 1 / 6

2 Precautionary Statements - Response IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention IF ON SKIN: Wash with plenty of soap and water Take off contaminated clothing and wash it before reuse IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Call a poison center or doctor/physician if you feel unwell Precautionary Statements - Storage Store in a well-ventilated place. Keep container tightly closed Store locked up Precautionary Statements - Disposal Dispose of contents/container to an approved waste disposal plant 3. COMPOSITION/INFORMATION ON INGREDIENTS Chemical Name CAS No Weight-% 2-cyano-3-(4-hydroxyphenyl)acrylic acid First Aid Measures 4. FIRST-AID MEASURES Eye Contact Skin Contact Inhalation Ingestion Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Wash off immediately with soap and plenty of water. If skin irritation persists, call a physician. Take off contaminated clothing. Wash contaminated clothing before reuse. Remove to fresh air. Seek medical treatment in case of complaints. Rinse mouth thoroughly with water. Call a physician immediately. Most important symptoms and effects Symptoms May cause skin and eye irritation. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. 5. FIRE-FIGHTING MEASURES Suitable Extinguishing Media Carbon dioxide (CO2). Extinguishing powder. Large Fire Alcohol resistant foam. Unsuitable Extinguishing Media Water jet. Specific Hazards Arising from the Chemical Combustion products may be toxic. Hazardous Combustion Products Nitrogen oxides (NOx). Hydrogen cyanide. Carbon oxides. Protective equipment and precautions for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Page 2 / 6

3 6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Personal Precautions Environmental Precautions Use personal protective equipment as required. Ensure adequate ventilation. Avoid creating dust. Avoid contact with eyes and skin. Do not release into sewers or waterways. Methods and material for containment and cleaning up Methods for Containment Methods for Clean-Up Prevent further leakage or spillage if safe to do so. Take up mechanically. Place in appropriate containers for disposal. For waste disposal, see section 13 of the SDS. 7. HANDLING AND STORAGE Precautions for safe handling Advice on Safe Handling Wash thoroughly after handling. Use personal protection recommended in Section 8. Avoid breathing dust or fume. Use only in well-ventilated areas. Minimize dust generation and accumulation. Provide suction extractors if dust is formed. Avoid contact with skin and eyes. Conditions for safe storage, including any incompatibilities Storage Conditions Incompatible Materials Keep containers tightly closed in a dry, cool and well-ventilated place. Store locked up. Store only in unopened original containers. Protect from dampness and humidity. Store away from food stuffs. Protect from light. Avoid contact with air/oxygen. Strong acids. Acid anhydrides. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Exposure Guidelines No exposure limits noted for ingredient(s) Appropriate engineering controls Engineering Controls Ventilation systems. Individual protection measures, such as personal protective equipment Eye/Face Protection Skin and Body Protection Respiratory Protection Safety glasses. Suitable protective clothing. Use impervious gloves. In case of brief exposure or low pollution, use breathing filter apparatus. In case of intensive or longer exposure, use breathing apparatus that is independent of circulating air. General Hygiene Considerations Keep away from food, drink and animal feeding stuffs. Wash hands before breaks and immediately after handling the product. Take off all contaminated clothing and wash it before reuse. Page 3 / 6

4 9. PHYSICAL AND CHEMICAL PROPERTIES Information on basic physical and chemical properties Physical State Solid Appearance Light yellow powder Odor Characteristic Color Light yellow Odor Threshold Property Values Remarks Method ph Melting Point/Freezing Point C / F Boiling Point/Boiling Range Flash Point Not applicable Evaporation Rate Flammability (Solid, Gas) Product is not flammable Upper Flammability Limits Lower Flammability Limit Vapor Pressure Vapor Density Specific Gravity Water Solubility Solubility in other solvents Partition Coefficient Auto-ignition Temperature Decomposition Temperature Kinematic Viscosity Dynamic Viscosity Explosive Properties Not an explosive Oxidizing Properties Reactivity Not reactive under normal conditions. Chemical Stability Stable under recommended storage conditions. Possibility of Hazardous Reactions None under normal processing. Conditions to Avoid Keep out of reach of children. Incompatible Materials Strong acids. Acid anhydrides. Hazardous Decomposition Products Carbon oxides. Nitrogen oxides (NOx). Hydrogen cyanide. 10. STABILITY AND REACTIVITY Page 4 / 6

5 11. TOXICOLOGICAL INFORMATION Information on likely routes of exposure Product Information Eye Contact Skin Contact Inhalation Ingestion Causes serious eye irritation. Causes skin irritation. Avoid inhalation of dust. Do not taste or swallow. Information on physical, chemical and toxicological effects Symptoms Please see section 4 of this SDS for symptoms. Delayed and immediate effects as well as chronic effects from short and long-term exposure Carcinogenicity STOT - single exposure This product does not contain any carcinogens or potential carcinogens as listed by OSHA, IARC or NTP. May cause respiratory irritation. May cause drowsiness or dizziness. Numerical measures of toxicity 12. ECOLOGICAL INFORMATION Ecotoxicity An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Persistence/Degradability. Bioaccumulation. Mobility Other Adverse Effects Waste Treatment Methods 13. DISPOSAL CONSIDERATIONS Disposal of Wastes Contaminated Packaging Disposal should be in accordance with applicable regional, national and local laws and regulations. Disposal should be in accordance with applicable regional, national and local laws and regulations. Page 5 / 6

6 14. TRANSPORT INFORMATION DOT IATA IMDG Not regulated Not regulated Not regulated 15. REGULATORY INFORMATION International Inventories US Federal Regulations SARA 313 US State Regulations U.S. State Right-to-Know Regulations 16. OTHER INFORMATION NFPA HMIS Health Hazards Health Hazards Flammability Flammability Instability Physical Hazards Special Hazards Personal Protection Issue Date: Revision Date: Revision Note: 26-Nov Jan-2015 New format Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. End of Safety Data Sheet Page 6 / 6

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