CURRICULUM VITAE. Personal information. Education

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1 CURRICULUM VITAE Personal information Name: Winkens, Bjorn Address: Maaierhof JL Heerlen The Netherlands Telephones: (work) Bjorn.Winkens(at)maastrichtuniversity.nl Nationality: Dutch Place of birth: Oirsbeek Date of birth: 04/03/1977 Marital status: Married with two children Education 2006-Now University of Maastricht Faculty of Health Sciences Department of Methodology and Statistics Assistant Professor Courses: - Adaptive designs (pre-conference course, ISCB, Copenhagen, Denmark; 2008) - Statistical Learning and Data Mining III (Krems, Austria; 2009) - Advanced Topics in Survival Analysis (Reading, UK; 2009) - Intro to R (Maastricht, NL; 2012) University of Maastricht Faculty of Health Sciences Department of Methodology and Statistics PhD student Courses: - Introduction Problem Based Learning (certificate; 2001) - Tutortraining (certificate; 2001) - Statistics: part 2 regression analysis (certificate; 2002) - Scientific Presentation in English (certificate; 2002) - Scientific Writing in English 1 (certificate; 2002) - Scientific Writing in English 2 (certificate; 2002) - Longitudinal Data Analysis (Limburgs Universitair Centrum at Diepenbeek, Belgium; 2002) Catholic University of Nijmegen Faculty of Science, Mathematics and Informatics Department of Mathematics Specialisation: Applied Statistics. 1

2 Title report: Robustness of Empirical Bayes estimators of random parameters in Linear-Mixed models: a Monte Carlo study for a longitudinal Design. Graduation: March Zuyd University Heerlen University of Professional Education Mechanical Engineering Rombouts College (VWO) Brunssum Subjects: Dutch, English, Mathematics A, Mathematics B, Science, Economy I, Economy II. Work Experience January now University of Maastricht Faculty of Health, Medicine and Life sciences (FHML) School for Public Health and Primary Care (CAPHRI) Department of Methodology and Statistics Assistant Professor Responsibilities: Research: - Optimal and robust designs for randomized clinical trials with repeated measurements. - Optimal adaptive designs for randomized clinical trials with repeated measurements. - Writing scientific articles in English. - Reviewer for Value in Health - Reviewer for Statistics in Medicine Education: - Member taskforce Academic Education in bachelor s programme in medicine ( ) - Member planning group year 6 (2006-now) - Constructing a statistics programme within medical curriculum (2006; new curriculum 2011). - lecturing introductory statistics for medical students (2006-now). - lecturing introductory statistics for Life Science students (2006-now). - lecturing statistics for PhD-students: regression analysis and SPSS (2007-now). - tutoring PhD students for course of Prof. D.G. Kleinbaum: logistic regression and model strategies (2006, 2009). 2

3 Consultation: - Statistical and methodological consultation for researchers within the Faculty of Health, Medicine and Life Sciences. - Statistical and methodological consultation for medical doctors. - Statistical and methodological consultation for 6 th year medical students. Co-promotor: Name: Nicol A.C. Smeets Thesis title: Fetal volume measurements in the first trimester of pregnancy with three-dimensional ultrasound Promotor: prof dr. S.G. Oei prof dr ir. P.F.F. Wijn Co-promotor: dr B. Winkens Manuscript: November Name: Hugo A.J.M. de Wit Title project: Supporting Clinical Rules in the Evaluation of Elderly patients in Nursing homes (SCREEN) Promotor: prof dr. Jos M.G.A. Schols Co-promotor: dr. B. Winkens Manuscript: expected 2014/2015 July 2005 December 2005 University Hospital Aachen Medical Faculty RWTH Department of Medical Statistics Study coordinator Multicentre Randomised Controlled Clinical Trial: Triamcinolone versus ILM Peeling in persistent Macular Edema (TIME-Study) Responsibilities: Study coordination: - Monitoring of the centres. - Coordination and cooperation of the participating hospitals and surgeons. - Consultation in statistical issues of the study. - Quality control of the documentation. - Organise meetings between the study committees. - Organise meetings of all study participants. Research: - Statistical analysis of Multicentre Randomised Trials. - Interim analyses. - Non-inferiority trials. Education: - tutoring medical students: introductory statistics. 3

4 Consultation: - Consulting Medical Doctors and PhD-students. September 2001 June 2005 University of Maastricht Faculty of Health Sciences Department of Methodology and Statistics PhD-student Thesis title: Experimental design for linearly divergent treatment effects. Subjects: - Optimal statistical analysis of a clinical trial. - Efficient design of a future experiment. Promotor: prof dr. M. P. F. Berger. Manuscript: June Responsibilities: Research: - Statistical analysis of an experiment. - Derivation of mathematical formulae for variances and optimal number of repeated measures and sample sizes. - Writing scientific articles in English. Education: - lecturing introductory statistics for students at a midwife college. - tutoring Health Science students: introductory statistics. - tutoring PhD students for course of Prof. D.G. Kleinbaum: logistic regression and model strategies (2002, 2003) University of Maastricht Faculty of Health Sciences Department of Methodology and Statistics Trainee for 4 months Title: Robustness of Empirical Bayes estimators of random parameters in Linear-Mixed models: a Monte Carlo study for a longitudinal Design. Main subjects: - Bayesian statistics (Empirical Bayes estimators, Bayes risk). - Multilevel analysis. Responsibilities: - Programming in MLwiN and SPSS. - Data simulation. - Analytical derivation of formulae and proving theorems. - Writing report (Dutch). Report has resulted in a published article (see publications). 4

5 Publications: 2012: 1. Aarts, S., Winkens, B. & Akker, M. van den (2012). The Insignificance of Statistical Significance. European Journal of General Practice, 18, Alnima, T, Scheffers, I.J., Leeuw, P. de, Winkens, B., Jongen-Vancraybex, H.A., Tordoir, J.H.M., Schmidli, J., Mohaupt, M.G., Alleman, Y. & Kroon, A.A. (2012). Sustained acute voltage-dependent blood pressure decrease with prolonged carotid baroreflex activation in therapy-resistant hypertension. Journal of Hypertension, 30, Burda, M.H.F., Horst, F. van, Akker, M. van den, Stork, A.D.M., Mesters, I., Bours, S., Ploeg, M., Winkens, B. & Knottnerus, A. (2012). Harvesting experiential expertise to support safe driving for people with type 1 and type 2 diabetes mellitus: a qualitative study evaluated by peers in a survey. The Patient: Patient-Centered Outcomes Research, 5(4), Burda, M.H.F., Horst, F. van, Akker, M. van den, Stork, A.D.M., Weijden, T. van der, Attekum, T. van, Ploeg, M., Winkens, B. & Knottnerus, J.A. (2012). Supporting people with diabetes mellitus in applying for and participating effectively in paid work: validation of succesful diabetes-related behaviors by experiental experts and professional care providers. Journal of Occupational and Environmental Medicine, 54(12), Heeringa, R., Koeveringe, G.A. van, Winkens, B., Kerrebroeck, P.E.V. van & Wachter, S.G. de (2012). Do patients with OAB experience bladder sensations in the same way as healthy volunteers? A focus group investigation. Neurology and Urodynamics, 31, Lok, S.I., Winkens, B., Goldschmeding, R., Geffen, A.J.P. van, Nous, F.M.A., Kuik, J. van, Weide, P van der, Klopping, J.H., Kirkels, J.H., Lahpor, J.R., Doevendans, P.A., Jonge, N. de & Weger, R.A. de (2012). Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support. European journal of heart failure, 14, Odink, H, van den berg, a & Winkens, B. (2012). Technical and clinical long-term results of infrapopliteal percutaneous transluminal angioplasty for critical limb ischemia. Journal of Vascular and Interventional Radiology, 23, Rondagh, E.J.A., Bouwens, M.W.E., Riedl, R.G., Winkens, B., Ridder, R. de, Kaltenbach, T., Soetikno, R.M., Masclee, A.A.M. & Sanduleanu, S. (2012). Endoscopic appearance of proximal colorectal neoplasms and potential implications for colonoscopy in cancer prevention. Gastrointestinal Endoscopy, 75(6), Rondagh, E.J.A., Masclee, A.A.M., Valk, M.E. van der, Winkens, B., Bruine, A.P. de, Kaltenbach, T., Soetikno, R.M. & Sanduleanu, S. (2012). Nonpolypoid colorectal neoplasms: Gender differences in prevalence and malignant potential. Scandinavian Journal of Gastroenterology, 47(1),

6 10. Smeets, N., Dvinskikh, N.A., Winkens, B. & Oei, G. (2012). A new semi-automated method for fetal volume measurements with three-dimensional ultrasound: Preliminary results. Prenatal Diagnosis, 32, Smeets, N., Prudon, M, Winkens, B. & Oei, G. (2012). Fetal volume measurements with three dimensional ultrasound in the first trimester of pregnancy, related to pregnancy outcome, a prospective cohort study. BMC Pregnancy and Childbirth, 12, Stoot, J.H.M.B., Dam, R.M. van, Coelen, R. J., Winkens, B., Olde Damink, S., Bemelmans, M.H.A. & Dejong, C.H.C. (2012). The introduction of a laparoscopic liver surgery programme: a cost analysis of initial experience in a University hospital. Scandinavian Journal of Surgery, 101(1), Van der Garde, M, Winkens, B. & Roumen, F.J.M.E. (2012). Increased electivecaesarean section rate is not associated with a decreased serious morbidity rate for twins > 32 weeks gestation. Journal of Obstetrics and Gynaecology, 32, Verlijsdonk, J., Winkens, B., Boers, K, Scherjon, S.A. & Roumen, F.J.M.E. (2012). Suspected versus non-suspected small-for-gestational age fetuses at term: perinatal outcomes. Journal of Maternal-Fetal and Neonatal Medicine, 25, Versteylen, M., Bekkers, S.C.A.M., Smulders, M.W., Winkens, B., Mihl, C., Winkens, M.H.M., Leiner, T., Waltenberger, J.L., Kim, RJ & Gorgels, A.P. (2012). Performance of angiographic electrocardiographic and MRI methods to assess the area at risk in acute myordial infarction. Heart, 98, Visschers, R.G.J., Gemert, W.G. van, Winkens, B., Soeters, P.B. & Olde Damink, S. (2012). Guided treatment improves outcome of patients with enterocutaneous fistulas. World Journal of Surgery, 36(10), Weg, K. Van der, Bekkers, S.C.A.M., Winkens, B., Lemmert, M.E., Schalla, S., Crijns, H.J.G.M., Waltenberger, J. & Gorgels, A.P.M. (2012). Evaluation of the electrocardiogram in identifying and quantifying lateral involvement in nonanterior wall infarction using cardiovascular magnetic resonance imaging. Journal of Electrocardiology, 45, : 1. Boesten, H.M.J., Harings, L, Winkens, B., Knottnerus, A. & Weijden, T. van der (2011). Defining antimicrobial prescribing quality indicators: what is a new prescription? European Journal of Clinical Pharmacology, 67, Hamers, L., Linssen, C.F., Lance, M.D., Maessen, J.G., Weerwind, P., Winkens, B., Bergmans, D.C. & Mook, W.N. van (2011). Positive cultures from cardiopulmonary bypass: prevalence and relevance regarding postoperative infection. European Journal of Cardio-Thoracic Surgery, 40, Heeringa, R., Koeveringe, G.A. van, Winkens, B., Kerrebroeck, P.E.V. van & Wachter, S.G. de (2011). Degree of urge, perception of bladder fullness and bladder volume - how are they related. Journal of Urology, 186(4),

7 2010: 4. Hoogland, E.R., Snoeijs, M.G., Winkens, B., Christiaans, M.H. & Heurn, L.W. (2011). Kidney transplantation from donors after cardiac death: uncontrolled versus controlled donation. American Journal of Transplantation, 11, Huntjens, K.M., Geel, T.A. Van, Blonk, M. C., Hegeman, J. H., Elst, M. van der, Willems, P., Geusens, P.P., Winkens, B., Brink, P. & Helden, S.H. Van (2011). Implementation of osteoporosis guidelines: a survey of five large fracture liaison services in the Netherlands. Osteoporosis International, 22(7), Jansen, S., Goedhard, J., Winkens, B. & Deursen, C.Th.B.M. van (2011). Preparation prior to colonoscopy: A randomized trial comparing different regimes. European Journal of Gastroenterology & Hepatology, 23, Koelewijn- van Loon, M.S., Eurlings, J.W.G., Winkens, B., Elwyn, G., Grol, R.P.T.M., Steenkiste, B. van & Weijden, T. van der (2011). Small but important errors in cariovascular risk calculation by practice nurses: a cross-sectional study in randomised trial setting. International Journal of Nursing Studies, 48, Ottenheijm, R.P., Joore, M.A., Walenkamp, G.H., Weijers, R.E., Winkens, B., Cals, J.W.L., Bie, R.A. de & Dinant, G.J. (2011). The Maastricht Ultrasound Shoulder pain trial (MUST): ultrasound imaging as a diagnostic triage tool to improve management of patients with non-chronic shoulder pain in primary care. BMC Musculoskeletal Disorders, 12, Rondagh, E.J.A., Sanduleanu, S., Clercq, C.M.C. le, Winkens, B. & Masclee, A.A.M. (2011). Diverticulosis and colorectal polyps at younger age: a possible link? European Journal of Gastroenterology & Hepatology, 23(11), Rondagh, E.J.A., Masclee, A.A.M., Bouwens, M.W.E., Winkens, B., Riedl, R.G., Bruine, A.P. de, Ridder, R. de, Kaltenbach, T., Soetikno, R.M. & Sanduleanu, S. (2011). Endoscopic red flags for the detection of high-risk serrated polyps: an observational study. Endoscopy, 43(12), Smeets, N., Winkens, B. & Oei, G. (2011). Learning curve of volume measurements by three-dimensional ultrasound with a rotational multi-planar technique. European Journal of Obstetrics & Gynecology and Reproductive Biology, 159, Visschers, R.G.J., Olde Damink, S., Gehlen, J.M., Winkens, B., Soeters, P.B. & Gemert, W.G. van (2011). Treatment of hypertriglyceridemia in patients receiving parenteral nutrition. Journal of Parenteral and Enteral Nutrition, 35(5), Vries, E.E. de, Hoogland, E.R., Winkens, B., Snoeijs, M.G. & Heurn, L.W.E. (2011). Renovascular resistance of machine-perfused DCD kidneys is associated with primary nonfunction. American Journal of Transplantation, 11(12), Wind, J., Snoeijs, M.G., Vliet, J.A. van der, Winkens, B., Christiaans, M.H.L., Hoitsma, A.J. & Heurn, L.W.E. (2011). Preservation of kidneys from controlled donors after cardiac death. British Journal of Surgery, 98(9), Wlazlo, N., Winkens, B., Vleuten, C.P.M. van der & Peters, W.G. (2011). Near-peer teaching in het coschap interne Geneeskunde:een gerandomiseerde cross-over trial. Tijdschrift voor Medisch Onderwijs, 30,

8 1. Broek, M.A. van den, Olde Damink, S., Winkens, B., Broelsch, C.E., Malago, M., Paul, A. & Saner, F.H. (2010). Procalcitonin as a prognostic marker for infectious complications in liver transplant recipients in an intensive care unit. Liver Transplantation, 16(3), Demoulin, C., Verbunt, A.M.C.F., Winkens, B., Knottnerus, J.A. & Smeets, R.J.E.M. (2010). Usefulness of perceived level of exertion in patients with chronic low back pain attending a physical training programme. Disability and Rehabilitation, 32(3), Houben, P.H.H., Weijden, T. van der, Winkens, B., Winkens, R.A.G. & Grol, R. (2010). Pretest expectations strongly influence interpretation of abnormal laboratory results and further management. BMC Family Practice, 11, Huntjens, K.M., Kosar, S., Geel, T.A. Van, Geusens, P.P., Willems, P., Kessels, A.G.H., Winkens, B., Brink, P. & Helden, S.H. Van (2010). Risk of subsequent fracture and mortality within 5 years after a non-vertebral fracture. Osteoporosis International, 21(12), Koelewijn- van Loon, M.S., Weijden, T. van der, Ronda, G., Steenkiste, B.C. van, Winkens, B., Elwyn, G. & Grol, R. (2010). Improving lifestyle and risk perception through patient involvement in nurse-led cardiovascular risk management: A clusterrandomized controlled trial in primary care. Preventive Medicine, 50(1-2), Lok, S.I., Winkens, B., Dimopoulos, K., Fernandes, S.M., Gatzoulis, M.A., Landzberg, M.J. & Mulder, B J. (2010). Recurrence of cerebrovascular events in young adults with a secundum atrial septal defect. International Journal of Cardiology, 142(1), Mingels, A.M., Jacobs, L.H., Kleijnen, V.W., Laufer, E.M., Winkens, B., Hofstra, L., Wodzig, W. & Dieijen-Visser, M.P. van (2010). Cardiac troponin T elevations, using highly sensitive assay, in recreational running depend on running distance. Clinical research in cardiology, 99(6), Ploumen, M.A.M., Baur, L.H.B., Streppel, M.J., Bolt, C.L.B., Winkens, B., Winkens, R.A.G. & Stoffers, H. (2010). Age is an independent risk factor for left atrial dysfunction: results from an observational study. Netherlands Heart Journal, 18(5), Sloten, T.T. van, Savelberg, H.H.C.M., Duimel-Peeters, I., Winkens, B. & Schaper, N.C. (2008, September 7). Neuropathy, sarcopenia and body mass index are determinants of physical inactivity in persons with type 2 diabetes. unknown, EASDcongres. 10. Snoeijs, M.G., Winkens, B., Heemskerk, M.B., Hoitsma, A.J., Christiaans, M.H., Buurman, W.A. & Heurn, L.W.E. (2010). Kidney transplantation from donors after cardiac death: a 25-year experience. Transplantation, 90(10), : 1. Aarts, S., Akker, M. van den, Boxtel, M.P.J. van, Jolles, J., Winkens, B. & Metsemakers, J.F.M. (2009). Diabetes mellitus type II as a risk factor for depression: a lower than expected risk in a general practice setting. European Journal of Epidemiology, 24(7),

9 2. Geel, A.C.M. Van, Helden, S.H. Van, Geusens, P.P., Winkens, B. & Dinant, G.J. (2009). Clinical subsequent fractures cluster in time after first fractures. Annals of the Rheumatic Diseases, 68, Geel, A.C.M. Van, Geusens, P.P., Winkens, B., Sels, J.P. & Dinant, G.J. (2009). Measures of bioavailable serum testosterone and estradiol and their relationships with muscle mass, muscle strength and bone mineral density in postmenopausal women: a cross-sectional study. European Journal of Endocrinology, 160(4), Heeringa, R., Linden, F. van der & Winkens, B. (2009). Carotisendarteriëctomie: lange termijn resultaten in een niet-opleidingsziekenhuis. Nederlands Tijdschrift voor Heelkunde, 18, Lima Passos, V., Tan, E.S., Winkens, B. & Berger, M.P.F. (2009). Optimal design for one- and two-color mircoarrays using mixed models: a comparative evaluation of their efficiencies. Journal of Computational Biology, 16, Loon, M.H.G. Van, Weijden, G.D.E.M. van der, Steenkiste, B.C. van, Ronda, G.M., Winkens, B., Severens, J.L., Wensing, M., Elwyn, G. & Grol, R.P.T.M. (2009). Involving patients in cardiovascular risk management using nurse-led clinics: a cluster-randomised controlled trial in primary care. Canadian Medical Association Journal, 181(12), Petit, S.F., Aerts, H.J.W.L., Loon, J.G.M. van, Offermann, C., Houben, R.M.A., Winkens, B., Ollers, M.C., Lambin, P., Ruysscher, D.K.M. de & Dekker, A.L.A.J. (2009). Metabolic control probability in tumour subvolumes or how to guide tumour dose redistributions in non-small cell lung cancer (NSCLC): An exploratory clinical study. Radiotherapy and Oncology, 91, Visschers, R.G., Olde Damink, S.W., Schreurs, M., Winkens, B., Soeters, P.B. & Gemert, W.G. van (2009). Development of hypertriglyceridemia in patients with enterocutaneous fistulas. Clinical Nutrition, 28(3), : 1. Visschers, R.G.J., Olde Damink, S.W., Bekkum, M. van, Winkens, B., Soeters, P.B. & Gemert, W.G. van (2008). Health-related quality of life in patients treated for enterocutaneous fistula. British Journal of Surgery, 95(10), Visschers, R.G.J., Olde Damink, S.W., Winkens, B., Soeters, P.B. & Gemert, W.G. van (2008). Treatment strategies in 135 consecutive patients with enterocutaneous fistulas. World Journal of Surgery, 32(3), : 1. Helden, S.H. Van, Cauberg, E., Geussens, P.P., Winkens, B., Weijden, T. van der & Brink, P. (2007). The fracture and osteoporosis outpatient clinic: an effective strategy for improving implementation of an osteoporosis guideline. Journal of Evaluation in Clinical Practice, 13(5), Winkens, B., Schouten, H.J.A., Breukelen, G.J.P. van & Berger, M.P.F. (2007). Optimal designs for clinical trials with second-order polynomial treatment effects. Statistical Methods in Medical Research, 16(6),

10 3. Winkens, B., Breukelen, G.J.P. van, Schouten, H.J.A. & Berger, M.P.F. (2007). Randomized clinical trials with a pre- and a post-treatment measurement: repeated measures versus ANCOVA models. Contemporary Clinical Trials, 28(6), : 1. Winkens, B., Schouten, H.J.A., Breukelen, G.J.P. van & Berger, M.P.F. (2006). Optimal number of repeated measures and group sizes in clinical trials with linearly divergent treatment effects. Contemporary Clinical Trials, 27(1), Winkens, B. (2006). Meer personen of meer metingen per persoon?, STATOR, 7, Winkens, B. (2006). Optimal design and analysis of clinical trials with repeated measures, CARE Bulletin, 35, : 1. Winkens, B. (2005, November 23). Optimal design and analysis of clinical trials with repeated measures. UM Universiteit Maastricht. Prom./coprom.: Prof. dr. M.P.F. Berger, Dr H.J. Schouten & Dr. G.J.P. van Breukelen. 2. Winkens, B., Schouten, H.J.A., Breukelen, G.J.P. van & Berger, M.P.F. (2005). Optimal time-points in clinical trials with linearly divergent treatment effects. Statistics in Medicine, 24(24), : 1. Candel, M.J.J.M. & Winkens, B. (2003). Performance of Empirical B.ayes Estimators of Level-2 Random Parameters in Multilevel A.nalysis: A. Monte Carlo Study for Longitudinal Designs. Journal of Educational and Behavioral Statistics, 28, Winkens, B., Schouten, H. J. A., van Breukelen, G. J. P., & Berger, M. P. F. (2003). Randomized clinical trials with a pre- and a post-treatment measure: repeated measures or ANCOVA?, Proceedings of the 18 th International Workshop on Statistical Modelling, , Belgium. Presentations: - Two-stage Adaptive versus Robust Designs for Repeated Measures Experiments (2011). Academy Colloquium Cost efficient and Optimal Designs for Social and Biomedical Sciences, Amsterdam, The Netherlands (oral presentation). - Two-stage Adaptive versus Robust Designs for Repeated Measures Experiments, (March 2010). Young statistician s meeting (YSM), Liverpool, UK (oral presentation) - Adaptive versus Robust Designs for Repeated Measures Experiments, (Augustus 2008). 29 th Annual Conference of the International Society for Clinical Biostatistics (ISCB), Copenhagen, Denmark (oral presentation). - Optimal and Robust Designs for Randomized Clinical Trials with Repeated Measurements, (July 2007). 28 th Annual Conference of the International Society for Clinical Biostatistics (ISCB), Alexandroupolis, Greece (poster presentation). - Optimal and Robust Designs for Randomized Clinical Trials with Repeated Measurements, (May 2007). Epidemiology and Biostatistics seminar, Erasmus Medical Center, Rotterdam, invited speaker. 10

11 - Optimal designs for clinical trials with second-order polynomial treatment effects, (July 2006). 23 th International Biometric Conference (IBC), Montreal, Canada (poster presentation). - Optimal design and analysis of clinical trials with repeated measurements (March 2006). Annual meeting of the Care And Public Health Research Institute (Caphri), Maastricht, The Netherlands. - Optimal number of repeated measures and group sizes in clinical trials with linearly divergent treatment effects, (August 2004). 25 th Annual Conference of the International Society for Clinical Biostatistics (ISCB), Leiden, The Netherlands. - Randomized clinical trials with a pre- and post-treatment measure: repeated measures or ANCOVA? (July 2003). 18 th International Workshop on Statistical Modelling (IWSM), Leuven, Belgium (poster presentation). - ANCOVA versus GLS in randomized clinical trials with a pre- and a post-treatment measure: heterogeneity of regression slopes and/or residual post-treatment variances, (May 2003). Dutch Biometric Conference, Kerkrade, The Netherlands. Further Work Experience: : private tutoring statistics for Heath Sciences students (University of Maastricht) : production co-operator CPS Color Sittard (during holidays and every saturday). 1996: private tutoring mathematics for part-time Science student. 1995: production co-operator Enraf Nonius (full-time for 4 months). Skills: Language: Dutch: English: German: French: native language excellent knowledge conversational knowledge basic knowledge Computer skills statistical programs: - SPSS - MLwiN - SAS - Scientific Workplace - Matlab Personal qualities: - teamplayer and independent worker - social - curious and inquisitive - patient and helpfull - pragmatic Hobbies: - soccer 11

12 - fitness - cycling 12

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