Publicaties Nefrologie 2014 Pagina

Size: px
Start display at page:

Download "Publicaties Nefrologie 2014 Pagina 1 31-3-2015"

Transcription

1 Publicaties Nefrologie 2014 Pagina Abbasi A, Stolk RP, Bakker SJL. Identification of relevant biomarkers for type 2 diabetes. Lancet Diabetes Endocrinol. 2014;2: Abbasi A, Corpeleijn E, Gansevoort RT, Gans ROB, Struck J, Schulte J, Hillege HL, Harst P van der, Stolk RP, Navis GJ, Bakker SJL. Circulating peroxiredoxin 4 and type 2 diabetes risk: the Prevention of Renal and Vascular Endstage Disease (PREVEND) study. Diabetologia. 2014;57: Abbasi A, Deetman PE, Corpeleijn E, Gansevoort RT, Gans ROB, Hillege HL, Harst P van der, Stolk RP, Navis GJ, Alizadeh BZ, Bakker SJL. Bilirubin as a potential causal factor in type 2 diabetes risk: a Mendelian randomization study. Diabetes 2014;Nov 3. [Epub] 4. Abbasi A, Stolk RP, Bakker SJL. Comment on Vassy et al. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 2014;63: Diabetes. 2014;63:e Abdelmalek JA, Gansevoort RT, Lambers Heerspink HJ, Ix JH, Rifkin DE. Estimated albumin excretion rate versus urine albumin-creatinine ratio for the assessment of albuminuria: a diagnostic test study from the Prevention of Renal and Vascular Endstage Disease (PREVEND) Study. Am J Kidney Dis. 2014;63: Adema AY, Borst MH de, Wee PM ter, Vervloet MG; NIGRAM Consortium including Sanders JSF, Bakker SJL, Navis GJ. Dietaryand pharmacological modification of fibroblast growth factor-23 in chronic kidney disease. J Ren Nutr. 2014;24: Adepu S, Katta K, Tietge UJ, Kwakernaak AJ, Dam W, Goor H van, Dullaart RPF, Navis GJ, Bakker SJL, Born J van den. Hepatic syndecan-1 changes associate with dyslipidemia after renal transplantation. Am J Transplant. 2014;14: Agterhuis DE, Mulder AH, Roozendaal C, Stegeman CA, Laverman GD. A false-positive antineutrophil cytoplasmic antibody proteinase 3 test in a patient with pulmonary-renal syndrome. J Rheumatol. 2014;41: Alkhalaf A, Landman GW, Hateren KJ van, Groenier KH, Mooyaart AL, Heer E de, Gans ROB, Navis GJ, Bakker SJL, Kleefstra N, Bilo HJ. Sex specific association between carnosinase gene CNDP1 and cardiovascular mortality in patients with type 2 diabetes (ZODIAC-22). J Nephrol. 2014;Apr 23. [Epub] 10. Angelantonio Di E, Gao P, Khan H, Butterworth AS, Wormser D, Kaptoge S et al, including Bakker SJL. Emerging Risk Factors Collaboration. Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA 2014;311: Arends S, Berden JHM, Grootscholten C, Derksen RH, Berger SP, Sévaux RG de, Voskuyl AE, Bijl M; Dutch Working Party on SLE.Arking DE, Pulit SL, Crotti L, Harst P van der, Munroe PB, Koopmann TT et al; Consortium; COGENT Consortium, DCCT/EDIC, emerge Consortium, HRGEN Consortium including Navis GJ et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet. 2014;46: Arends S, Berden JHm, Grootscholten C, Derksen RH, Berger SP, Sévaux RG de, Voskuyl AE, Bijl M; Dutch Working Party on SLE. Induction therapy with short-term high-dose intravenous cyclophosphamide followed by mycophenolate mofetil in proliferative lupus nephritis. Neth J Med. 2014;72: Aslan A, Jongman RM, Moser J, Stegeman CA, Goor H van, Diepstra A, Heuvel MC van den, Heeringa P, Molema G, Zijlstra JG, Meurs M van. The renal angiopoietin/tie2 system in lethal human sepsis. Crit Care. 2014;18: Assa S, Hummel YM, Voors AA, Kuipers J, Westerhuis R, Groen H, Bakker SJL, Muller Kobold AC, Oeveren W van, Struck J, Jong PE de, Franssen CFM. Hemodialysis-induced regional left ventricular systolic dysfunction and inflammation: a cross-sectional study. Am J Kidney Dis. 2014;64: Athanasiou Y, Zavros M, Arsali M, Papazachariou L, Demosthenous P, Savva I, Voskarides K, On Behalf Of The MAURO Working Group, Trujillano D, Bullich G, Ballarin J, Torra R, Estivill X,

2 Publicaties Nefrologie 2014 Pagina Ars E et al, including Borst MH de, Navis GJ. Genetic diseases and molecular genetics. Nephrol Dial Transplant. 2014;29 Suppl 3:iii339-iii Baia LC, Berg E van den, Vervloet MG, Heilberg IP, Navis GJ, Bakker SJL, Geleijnse JM, Kromhout D, Soedamah-Muthu SS, Borst MH de; on behalf of the NIGRAM consortium. Fish and omega-3 fatty acid intake in relation to circulating fibroblast growth factor 23 levels in renal transplant recipients. Nutr Metab Cardiovasc Dis. 2014;24: Berg E van den, Pasch A, Westendorp WH, Navis GJ, Brink EJ, Gans ROB, Goor H van, Bakker SJL. Urinary sulfur metabolites associate with a favorable cardiovascular risk profile and survival benefit in renal transplant recipients. J Am Soc Nephrol. 2014;25: Boer YS de, Gerven NM van, Zwiers A, Verwer BJ, Hoek B van, Erpecum KJ van, Beuers U et al; Dutch Autoimmune Hepatitis Study Group; LifeLines Cohort Study; Study of Health in Pomerania including collaborators including Navis GJ. Genome-wide association study identifies variants associated with autoimmune hepatitis type 1. Gastroenterology. 2014;147: Boersema M, Born JC van den, Ark J van, Harms G, Seelen MAJ, Dijk MC van, Goor H van, Navis GJ, Popa ER, Hillebrands JL. CD16(+) monocytes with smooth muscle cell characteristics are reduced in human renal chronic transplant dysfunction. Immunobiology. 2014;pii:S (14) Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA et al, including Bakker SJL; CORtisol NETwork (CORNET) Consortium. Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin. PLoS Genet. 2014;10:e Braam B, Joles JA, Danishwar AH, Gaillard CAJM. Cardiorenal syndrome--current understanding and future perspectives. Nat Rev Nephrol. 2014;10: Broekman KE, Sinkeler SJ, Waanders F, Bartels GL, Navis GJ, Janssen WM. Volume control in treatment-resistant congestive heart failure: role for peritoneal dialysis. Heart Fail Rev. 2014;19: Brouwers FP, Gilst WH van, Damman K, Berg M van den, Gansevoort RT, Bakker SJL, Hillege HL, Veldhuisen DJ van, Harst P van der, Boer RA de. Clinical risk stratification optimizes value of biomarkers to predict new onset heart failure in a community-based cohort. Circ Heart Fail. 2014;7: Cabrera-López C, Ars E, Marti T, Harris PC, Torra R, Clerckx C et al including Gansevoort RT, Bakker SJL, Gaillard CAJM. Renal development and cystic diseases. Nephrol Dial Transplant. 2014;29 Suppl 3:iii73-iii Casteleijn NF, Jager RL de, Neeleman MP, Blankestijn PJ, Gansevoort RT. Chronic kidney pain in autosomal dominant polycystic kidney disease: a case report of successful treatment by catheter-based renal denervation. Am J Kidney Dis. 2014;63: Casteleijn NF, Spithoven EM, Rookmaaker MB, Vergouwen MD, Gansevoort RT. Bilateral cysts in the choroid plexus in a patient with autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. 2014; Aug 7. [Epub] 27. Casteleijn NF, Visser FW, Drenth JP, Gevers TJ, Groen GJ, Hogan MC, Gansevoort RT; DIPAK Consortium. A stepwise approach for effective management of chronic pain in autosomal-dominant polycystic kidney disease. Nephrol Dial Transplant. 2014;29 Suppl 4:iv Casteleijn NF, Blankestijn PJ, Gansevoort RT. In reply to 'catheter-based renal denervation in ADPKD: just for pain control?'. Am J Kidney Dis. 2014;64: CLOTS (Clots in Legs Or stockings after Stroke) Trials collaboration including Navis GJ et al. Effect of intermittent pneumatic compression on disability, living circumstances, quality of life, and hospital costs after stroke: secondary analyses from CLOTS 3, a randomised trial. Lancet Neurol. 2014;13:

3 Publicaties Nefrologie 2014 Pagina Cornec-Le Gall E, Hourmant M, Morin MP, Charasse C, Renaudineau E, Wehbe B et al; GENKYST Study Group, Audrézet MP, Férec C, Le Meur Y, Spithoven EM, Meijer E, Borns C, Boertien WE, Kappert P, Greuter MJ, Jagt E van der, Jong PE de, Gaillard CAJM, Gansevoort RT et al. Adpkd - clinical outcome studies. Nephrol Dial Transplant. 2014;29 Suppl 3:iii5-iii6 31. Coresh J, Turin TC, Matsushita K, Sang Y, Ballew SH, Appel LJ et al, including Jong PE de, Gansevoort RT, Bakker SJL; for the CKD Prognosis Consortium. Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality. JAMA. 2014;311: Cornelis T, Tennankore KK, Goffin E, Rauta V, Honkanen E, Ozyilmaz A, Thanaraj V, Jayanti A, Mitra S, van der Sande FM, Kooman JP, Chan CT. An international feasibility study of home haemodialysis in older patients. Nephrol Dial Transplant. 2014;29: Corsetti JP, Gansevoort RT, Bakker SJL, Sparks CE, Vart P, Dullaart RPF. Apolipoprotein B attenuates albuminuria-associated cardiovascular disease in Prevention of Renal and Vascular Endstage Disease (PREVEND) Participants. J Am Soc Nephrol. 2014;25: Damman J, Bloks VW, Daha MR, Most P van der, Sanjabi B, Vlies P van der, Snieder H, Ploeg RJ, Krikke C, Leuvenink HG, Seelen MAJ. Hypoxia and complement-and-coagulation pathways in the deceased organ donor as the major target for intervention to improve renal allograft outcome. Transplantation. 2014;Nov 25. [Epub] 35. Deetman PE, Bakker SJL, Kwakernaak AJ, Navis GJ, Dullaart RPF; PREVEND Study Group, including collaborators Jong PE de, Gansevoot RT et al. The relationship of the anti-oxidant bilirubin with free thyroxine is modified by insulin resistance in euthyroid subjects. PLoS One. 2014;9:e Deetman PE, Said MY, Kromhout D, Dullaart RPF, Kootstra-Ros JE, Sanders JSF, Seelen MAJ, Gans ROB, Navis GJ, Joosten MM, Bakker SJL. Urinary urea excretion and long-term outcome after renal transplantation. Transplantation. 2014;Nov 12. [Epub] 37. Devuyst O, Knoers NV, Remuzzi G, Schaefer F; Board of the Working Group for Inherited Kidney Diseases of the European Renal Association and European Dialysis and Transplant Association, including collaborators Antignac C, Bindels R, Chauveau D, Devuyst O, Emma F, Gansevoort RT et al. Rare inherited kidney diseases: challenges,opportunities, and perspectives. Lancet. 2014;383: Doesum WB van, Abdulahad WH, Dijk MC van, Dolff S, Son WJ van, Stegeman CA, Sanders JSF. Characterization of urinary CD4(+) and CD8(+) T cells in kidney transplantation patients with polyomavirus BK infection and allograft rejection. Transpl Infect Dis. 2014;16: Dontje ML, Greef MH de, Krijnen WP, Corpeleijn E, Kok T, Bakker SJL, Stolk RP, Schans CP van der. Longitudinal measurement of physical activity following kidney transplantation. Clin Transplant. 2014;28: Dullaart RPF, Boersema J, Lefrandt JD, Wolffenbuttel BHR, Bakker SJL. The inverse association of incident cardiovascular disease with plasma bilirubin is unaffected by adiponectin. Atherosclerosis. 2014;235: Dullaart RPF, Haperen R van, Born J van den, Goor H van, Crom R de, Tol A van. No renal phenotype in human phospholipid transfer protein transgenic apolipoprotein E deficient mice despite severe aortic atherosclerosis. Clin Lab 2014:60:1659: Dijkstra AE, Smolonska J, Berge M van den, Wijmenga C, Zanen P, Luinge MA et al. LifeLines Cohort study including collaborators Navis GJ et al. Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One. 2014;9:e Emerging Risk Factors Collaboration, Di Angelantonio E, Gao P, Khan H,Butterworth AS, Wormser D, Kaptoge S, Kondapally Seshasai SR, Bakker SJL et al. Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA. 2014;26;311: Engel MF, Bruns AH, Hulscher ME, Gaillard CAJM, Sankatsing SU, Teding van Berkhout F, Emmelot-Vonk MH, Kuck EM, Steeghs MH, Breeijen JH den, Stellato RK, Hoepelman AI, Oosterheert JJ. A tailored implementation strategy to reduce the duration of intravenous

4 Publicaties Nefrologie 2014 Pagina antibiotic treatment in community-acquired pneumonia: a controlled before-and-after study. Eur J Clin Microbiol Infect Dis. 2014;33: Eny KM, Lutgers HL, Maynard J, Klein BE, Lee KE, Atzmon G, Monnier VM, Vliet-Ostaptchouk JV van, Graaff R, Harst P van der, Snieder H, Klauw MM van der, Sell DR, Hosseini SM, Cleary PA, Braffett BH, Orchard TJ, Lyons TJ, Howard K, Klein R, Crandall JP, Barzilai N, Milman S, Ben-Avraham D; LifeLines Cohort Study Group; DCCT/EDIC Research Group; coloborators including Navis GJ et al. GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Diabetologia 2014;57: Ettema EM, Zittema D, Kuipers J, Gansevoort RT, Vart P, Jong PE de, Westerhuis R, Franssen CFM. Dialysis Hypotension: A role for inadequate increase in arginine Vasopressin levels? A Systematic Literature Review and Meta-Analysis. Am J Nephrol. 2014;39: Faria B, Henriques C, Matos AC, Daha MR, Pestana M, Seelen MAJ. Combined C4d and CD3 immunostaining predicts IgA nephropathy progression. Clin Exp Immunol. 2014;Sep 30. [Epub] 48. Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, GU X et al, including collaborators Jong PE de, Navis GJ et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014;3:95: Gastel MD van, Meijer E, Scheven LE, Struck J, Bakker SJL, Gansevoort RT. Modifiable factors associated with copeptin concentration: A general population cohort. Am J Kidney Dis. 2014; Oct 31. [Epub] 50. Gelder T van, Berden JH, Berger SP. To TDM or not to TDM in lupus nephritis patients treated with MMF? Nephrol Dial Transplant. 2014;May 8. [Epub] 51. Gerrits EG, Alkhalaf A, Landman GW, Hateren KJ van, Groenier KH, Struck J, Schulte J, Gans ROB, Bakker SJL, Kleefstra N, Bilo HJ. Serum peroxiredoxin 4: a marker of oxidative stress associated with mortality in type 2 diabetes (ZODIAC-28). PLoS One. 2014;9:e Gieteling E, Leur JJ van de, Stegeman CA, Groeneveld PH. Accurate and fast diagnostic algorithm for febrile urinary tract infections in humans. Neth J Med. 2014;72: Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO et al including Bakker SJL, Gansevoort RT et al. Genome-wide association study of kidney function decline in individuals of European descent. Kidney Int. 2014;Dec 10. [Epub] 54. Hallan SI, Gansevoort RT. Should we diagnose CKD using the 'one-size fits all' KDIGO 2012 guideline or do we need a more complex age-specific classification system? Nephrol Dial Transplant. 2014;Jan 20. [Epub] 55. Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH et al; Generation Scotland Consortium; LifeLines Cohort study, Colloborators including Navis GJ; GIANT Consortium, Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet. 2014;1;10(7) 56. Hu N, Mora-Jensen H, Theilgaard-Mönch K, Doornbos-van der Meer B, Huitema MG, Stegeman CA, Heeringa P, Kallenberg CGM, Westra J. Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177. PLoS One. 2014;13;9:e Huang Y, Caputo CR, Noordmans GA, Yazdani S, Monteiro LH, Born J van den, van Goor H, Heeringa P, Korstanje R, Hillebrands JL. Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice. PLoS One. 2014;17;9:e Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M et al including Navis GJ. Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) Consortium Neurology Working Group; CARDIoGRAM Consortium; Consortium Hemostatic Factor Working Group. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014;34:

5 Publicaties Nefrologie 2014 Pagina Humalda JK, Assa S, Navis GJ, Franssen CFM, Borst MH de, Ogawa H et al including Gansevoort RT, Bakker SJL, Gaillard CAJM, Westerhuis R, Franssen CFM. Dialysis. Pathophysiology and clinical studies. Nephrol Dial Transplant. 2014;29 Suppl 3:iii501-iii Humalda JK, Navis GJ. Dietary sodium restriction: a neglected therapeutic opportunity in chronic kidney disease. Curr Opin Nephrol Hypertens. 2014;23: Huzen J, Wong LS, Veldhuisen DJ van, Samani NJ, Zwinderman AH, Codd V, Cawthon RM, Benus GF, Horst IC van der, Navis GJ, Bakker SJL, Gansevoort RT, Jong PE de, Hillege HL, Gilst WH van, Boer RA de, Harst P van der. Telomere length loss due to smoking and metabolic traits. J Intern Med. 2014;275: Ipema KJ, Westerhuis R, Schans CP van der, Jong PE de, Gaillard CAJM, Krijnen WP, Slart RH, Franssen CFM. Effect of nocturnal haemodialysis on body composition. Nephron Clin Pract. 2014; 2014;128: Jayakumar C, Nauta FL, Bakker SJL, Bilo H, Gansevoort RT, Johnson MH, Ramesh G. Netrin- 1, a urinary proximal tubular injury marker, is elevated early in the time course of human diabetes. J Nephrol. 2014;27: Jong K de, Boezen HM, Kromhout H, Vermeulen R, Postma DS, Vonk JM,; LifeLines Cohort Study, including collaborators Navis GJ et al. Pesticides and other occupational exposures are associated with airway obstruction: the LifeLines cohort study. Occup Environ Med 2014:71: Jong K de, Vonk JM, Kromhout H, Vermeulen R, Postma DS, Boezen HM; LifeLines Cohort Study, including collaborators Navis GJ et al. NOS1: a susceptibility gene for reduced level of FEV1 in the setting of pesticide exposure. Am J Respir Crit Care Med. 2014;v15;190: Joode AAE de, Sanders JSF, Smid MW, Stegeman CA. Plasmapheresis rescue therapy in progressive systemic ANCA-associated vasculitis: Single-center results of stepwise escalation of immunosuppression. J Clin Apher. 2014;29: Joode AAE de, Roozendaal C, Leij MJ van der, Bungener LB, Sanders JSF, Stegeman CA. Performance of two strategies for urgent ANCA and anti-gbm analysis in vasculitis. Eur J Intern Med. 2014;25: Joosten H, Visser ST, Eersel ME van, Gansevoort RT, Bilo HJ, Slaets JP, Izaks GJ. Statin use and cognitive function: population-based observational study with long-term follow-up. PLoS One. 2014;9:e Joosten MM, Gansevoort RT, Mukamal KJ, Lambers Heerspink HJ, Geleijnse JM, Feskens EJ, Navis GJ, Bakker SJL; PREVEND Study Group. Sodium excretion and risk of developing coronary heart disease. Circulation 2014;129: Joosten MM, Pai JK, Bertoia ML, Gansevoort RT, Bakker SJL, Cooke JP, Rimm EB, Mukamal KJ. β2-microglobulin, cystatin C, and creatinine and risk of symptomatic peripheral artery disease. J Am Heart Assoc. 2014;3(4) 71. Kallenberg CGM, Stegeman CA, Abdulahad WH, Heeringa P. In Reply to 'Rituximab and B-Cell Return in ANCA-Associated Vasculitis'. Am J Kidney Dis. 2014;63: Keyzer CA, Riphagen IJ, Joosten MM, Navis GJ, Muller Kobold AC, Kema IP, Bakker SJL, Borst MH de. Associations of 25(OH) and 1,25(OH)(2) Vitamin D with Long-Term Outcomes in Stable Renal Transplant Recipients. J Clin Endocrinol Metab. 2014;Oct 31. [Epub] 73. Kieneker LM, Gansevoort RT, Mukamal KJ, Boer RA de, Navis GJ, Bakker SJL, Joosten MM. Urinary potassium excretion and risk of developing hypertension: The prevention of renal and vascular end-stage disease study. Hypertension. 2014;64: Kurnatowska I, Grzelak P, Masajtis-Zagajewska A, Kaczmarska M, Stefańczyk L,Vermeer C et al including Navis GJ; On Behalf Of Mauro Working Group. Ckd pathophysiology and clinical studies. Transplant. 2014;29 Suppl 3:iii148-iii Kwakernaak AJ, Krikken JA, Binnenmars SH, Visser FW, Hemmelder MH, Woittiez AJ, Groen H, Laverman GD, Navis GJ; Holland Nephrology study (HONEST) group including collaborators Borst MH de et al. Effects of sodium restriction and hydrochlorothiazide on RAAS blockade

6 Publicaties Nefrologie 2014 Pagina efficacy in diabetic nephropathy: a randomised clinical trial. Lancet Diabetes Endocrinol. 2014;2: Lambers Heerspink HJ, Weldegiorgis M, Inker LA, Gansevoort RT, Parving HH, Dwyer JP, Mondal H, Coresh J, Greene T, Levey AS, Zeeuw D de. Estimated GFR decline as a surrogate end point for kidney failure: a post hoc analysis from the reduction of end points in non-insulindependent diabetes with the angiotensin II antagonist losartan (RENAAL) study and Irbesartan Diabetic Nephropathy Trial (IDNT). Am J Kidney Dis. 2014;63: Lambers Heerspink HJ, Gaillard CAJM, Gansevoort RT. Screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease. Ann Intern Med. 2014;161: Landman GW, van Dijk PR, Drion I, van Hateren KJ, Struck J, Groenier KH, Gans ROB, Bilo HJ, Bakker SJL, Kleefstra N. Midregional fragment of pro-adrenomedullin, new-onset albuminuria, and cardiovascular and all-cause mortality in patients with type 2 diabetes (ZODIAC-30). Diabetes Care. 2014;37: Laville M, Dorval M, Fort Ros J, Fay R, Cridlig J, Nortier JL, Juillard L, Dębska-Ślizień A, Fernández Lorente L, Thibaudin D, Franssen CFM, Schulz M, Moureau F, Loughraieb N, Rossignol P. Results of the HepZero study comparing heparin-grafted membrane and standard care show that heparin-grafted dialyzer is safe and easy to use for heparin-free dialysis. Kidney Int. 2014;86: Lepse N, Abdulahad WH, Rutgers A, Kallenberg CGM, Stegeman CA, Heeringa P. Altered B cell balance, but unaffected B cell capacity to limit monocyte activation in anti-neutrophil cytoplasmic antibody-associated vasculitis in remission. Rheumatology (Oxford). 2014;53: Li N, van der Sijde MR, Study LC, Bakker SJL, Dullaart RPF, Harst P van der, Gansevoort RT, Elbers CC, Wijmenga C, Snieder H, Hofker MH, Fu J. Pleiotropic effects of lipid genes on plasma glucose, HbA1c and HOMA-IR levels. Diabetes. 2014;63: Lintermans LL, Stegeman CA, Heeringa P, Abdulahad WH. T cells in vascular inflammatory diseases. Front Immunol. 2014;5:504 ecollection 2014;5:14 [Review] 83. Londen M van, Humalda JK, Aarts BM, Sanders JSF, Bakker SJL, Navis GJ, Borst MH de et al. Transplantation clinical 2. Nephrol Dial Transplant. 2014;29 Suppl 3:iii539-iii Maaten JM ter, Damman K, Hillege HL, Bakker SJL, Anker SD, Navis GJ, Voors AA. Creatinine excretion rate, a marker of muscle mass, is related to clinical outcome in patients with chronic systolic heart failure. Clin Res Cardiol. 2014; Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard CAJM, Wyck D van, Roubert B, Nolen JG, Roger SD; on behalf of the FIND-CKD Study Investigators. FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant. 2014;Jun 2. pii: gfu201. [Epub] 86. Mahmoodi BK, Yatsuya H, Matsushita K, Sang Y, Gottesman RF, Astor BC, Woodward M, Longstreth WT Jr, Psaty BM, Shlipak MG, Folsom AR, Gansevoort RT, Coresh J. Association of Kidney Disease Measures With Ischemic Versus Hemorrhagic Strokes: Pooled Analyses of 4 Prospective Community-Based Cohorts. Stroke. 2014;45: Meuleman Y, Brinke L ten, Kwakernaak AJ, Vogt L, Rotmans JI, Bos WJ, Boog PJ van der, Navis GJ, Montfrans GA van, Hoekstra T, Dekker FW, Dijk S van. Perceived barriers and support strategies for reducing sodium intake in patients with chronic kidney disease: a qualitative study. Int J Behav Med. 2014;Oct 9. [Epub] 88. Meijer E, Drenth JP, d'agnolo H, Casteleijn NF, Fijter JW de, Gevers TJ,Kappert P, Peters DJ, Salih M, Soonawala D, Spithoven EM, Torres VE, Visser FW, Wetzels JF, Zietse R, Gansevoort RT; DIPAK Consortium. Rationale and design of the DIPAK 1 study: a randomized controlled clinical trial assessing the efficacy of lanreotide to Halt disease progression in autosomal dominant polycystic kidney disease. Am J Kidney Dis. 2014;63: Meijers B, Glorieux G, Poesen R, Bakker SJL. Nonextracorporeal methods for decreasing uremic solute concentration: a future way to go? Semin Nephrol. 2014;34:228-43

7 Publicaties Nefrologie 2014 Pagina Meijers WC, Velde AR van der, Ruifrok WP, Schroten NF, Dokter MM, Damman K, Assa S, Franssen CFM, Gansevoort RT, Gilst WH van, Silljé HH, de Boer RA. Renal handling of galectin-3 in the general population, chronic heart failure, and hemodialysis. J Am Heart Assoc. 2014;18;3:e Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA et al, including Stegeman CA. Rituximab for the treatment of relapses in ANCA-associated vasculitis. Arthritis Rheumatol. 2014;Jul 21. [Epub] 92. Meijers B, Glorieux G, Poesen R, Bakker SJL. Nonextracorporeal methods for decreasing uremic solute concentration: a future way to go? Semin Nephrol. 2014;34: Meyer S, Brouwers FP, Voors AA, Hillege HL, de Boer RA, Gansevoort RT, Harst P van der, Rienstra M, van Gelder IC, Veldhuisen DJ van, Gilst WH van, Meer P van der. Sex differences in new-onset heart failure. Clin Res Cardiol. 2014;Nov 15. [Epub] 94. Miloslavsky EM, Specks U, Merkel PA, Seo P, Spiera R, Langford CA et al including Stegeman CA. Rituximab in ANCA-associated Vasculitis-Immune Tolerance Network Research Group. Rituximab for the treatment of relapses in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol. 2014;66: Moes DJ, Swen JJ, den Hartigh J, Straaten T van der, Homan van der Heide JJ, Sanders JSF, Bemelman FJ, de Fijter JW, Guchelaar HJ. Effect of CYP3A4*22, CYP3A5*3, and CYP3A combined genotypes on cyclosporine, everolimus, and tacrolimus pharmacokinetics in renal transplantation. CPT Pharmacometrics Syst Pharmacol. 2014;3:e Mohamed R, Ranganathan P, Jayakumar C, Nauta FL, Gansevoort RT, Weintraub NL, Brands M, Ramesh G. Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice. J Mol Med (Berl). 2014;92: Nacak H, Diepen M van, Goeij MC de, Rotmans JI, Dekker FW; including collaborators Franssen CFM et al. PREPARE-2 study Uric acid: association with rate of renal function decline and time until start of dialysis in incident pre-dialysis patients. BMC Nephrol. 2014;16;15: Navis GJ, Blankestijn PJ, Deegens J, De Fijter JW, Homan van der Heide JJ, Rabelink T, Krediet RT, Kwakernaak AJ, Laverman GD, Leunissen KM, Paassen P van, Vervloet MG, Wee PM, Wetzels JF, Zietse R, van Ittersum FJ; on behalf of the BIND-NL investigators. The Biobank of nephrological diseases in the Netherlands cohort: the string of pearls initiative collaboration on chronic kidney disease in the university medical centers in the Netherlands. Nephrol Dial Transplant. 2014;29: Otten HG, Joosten I, Allebes WA, Meer A van der, Hilbrands LB, Baas M et al, including Seelen MAJ, Sanders JSF. The PROCARE consortium: Toward an improved allocationstrategy for kidney allografts. Transpl Immunol. 2014;31: Oude Voshaar RC, Derks WJ, Comijs HC, Schoevers RA, Borst MH de, Marijnissen RM. Antidepressants differentially related to 1,25-(OH)₂ vitamin D₃ and 25-(OH) vitamin D₃ in late-life depression. Transl Psychiatry. 2014;4:e Pena MJ, Lambers Heerspink HJ, Hellemons ME, Friedrich T, Dallmann G, Lajer M, Bakker SJL, Gansevoort RT, Rossing P, Zeeuw D de, Roscioni SS. Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus. Diabet Med. 2014;31: Pennells L, Kaptoge S, White IR, Thompson SG, Wood AM; Emerging Risk Factors Collaboration including collaborators Gansevoort RT, Bakker SJL. Assessing risk prediction models using individual participant data from multiple studies. Am J Epidemiol. 2014;179: Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C et al. Australian Ovarian Cancer Study; GENICA Network; kconfab; LifeLines Cohort Study including Navis GJ et al. InterAct Consortium; Early Growth Genetics (EGG) Consortium, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Ong KK. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014;2:514:92-7

8 Publicaties Nefrologie 2014 Pagina Petzold K, Gansevoort RT, Ong AC, Devuyst O, Rotar L, Eckardt KU, Köttgen A,Pirson Y, Remuzzi G, Sandford R, Tesar V, Ecder T, Chaveau D, Torra R, Budde K,Le Meur Y, Wüthrich RP, Serra AL. Building a network of ADPKD reference centres across Europe: the EuroCYST initiative. Nephrol Dial Transplant. 2014;Suppl 4:iv26-32 Erratum in: Nephrol Dial Transplant. 2014;29: Riese H, Muñoz LM, Hartman CA, Ding X, Su S, Oldehinkel AJ, Roon AM van, Most PJ van der, Lefrandt J, Gansevoort RT, Harst P van der, Verweij N, Licht CM,Boomsma DI, Hottenga JJ, Willemsen G, Penninx BW, Nolte IM, Geus EJ de, Wang X, Snieder H. Identifying genetic variants for heart rate variability in the acetylcholine pathway. PLoS One. 2014;10;9:e Riphagen IJ, Deetman PE, Bakker SJL, Navis GJ, Cooper ME, Lewis JB, Zeeuw D de, Lambers Heerspink HJ. Bilirubin and progression of nephropathy in type 2 diabetes: A post-hoc analysis of RENAAL with independent replication in IDNT. Diabetes. 2014; Rocco M, Daugirdas J, Greene T, Lockridge R, Chan C, Pierratos A et al; FHN Trial Group, Laville M,Dorval M, Fort Ros J, Fay R, Cridlig J, Nortier JL et al including Franssen CFM. New dialysistechniques. Nephrol Dial Transplant. 2014;29 Suppl 3:iii37-iii Roger SD, Bock A, Carrera F, Eckardt KU, Gaillard CAJM, Wyck D van et al. Ckd anaemia. Nephrol Dial Transplant. 2014;29 Suppl 3:iii21-iii Rosmalen JG, Kema IP, Wüst S, van der Ley C, Visser ST, Snieder H, Bakker SJL. 24 h urinary free cortisol in large-scale epidemiological studies: short-term and long-term stability and sources of variability. Psychoneuroendocrinology. 2014;47: Ruilope LM, Agarwal R, Chan JC, Cooper ME, Gansevoort RT, Haller H, Remuzzi G,Rossing P, Schmieder RE, Nowack C, Ferreira AC, Pieper A, Kimmeskamp-Kirschbaum N, Bakris GL. Rationale, Design, and baseline characteristics of ARTS-DN: A Randomized study to assess the safety and efficacy of finerenone in patients with type 2 diabetes mellitus and a clinical diagnosis of diabetic nephropathy. Am J Nephrol. 2014;40: Sanders JSF, Abdulahad WH, Stegeman CA, Kallenberg CGM. Pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis and potential targets for biologic treatment. Nephron Clin Pract. 2014;128: Sharif A, Hecking M, Vries AP de, Porrini E, Hornum M, Rasoul-Rockenschaub S, Berlakovich G, Krebs M, Kautzky-Willer A, Schernthaner G, Marchetti P, Pacini G, Ojo A, Takahara S, Larsen JL, Budde K, Eller K, Pascual J, Jardine A, Bakker SJL, Valderhaug TG, Jenssen TG, Cohney S, Säemann MD. Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions. Am J Transplant. 2014;14: Scheven L, Joosten MM, Jong PE de, Bakker SJL, Gansevoort RT; PREVEND study group. The association of albuminuria with tubular reabsorption of uric acid: results from a general population cohort. J Am Heart Assoc. 2014;3:e Schulz T, Niesing J, Homan van der Heide JJ, Westerhuis R, Ploeg RJ, Ranchor AV. Great expectations? Pre-transplant quality of life expectations and distress after kidney transplantation: a prospective study. Br J Health Psychol. 2014;19: Shaffi K, Uhlig K, Perrone RD, Ruthazer R, Rule A, Lieske JC, Navis GJ, Poggio ED, Inker LA, Levey AS. Performance of creatinine-based GFR estimating equations in solid-organ transplant recipients. Am J Kidney Dis. 2014;63: Sidorenkov G, Navis GJ. Safety of ACE inhibitor therapies in patients with chronic kidney disease. Expert Opin Drug Saf. 2014;13: Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X et al; LifeLines Cohort Study including Navis GJ et al. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP consortia. Am J Hum Genet. 2014;3;95: Siwy J, Schanstra JP, Argiles A, Bakker SJL, Beige J, Boucek P et al including Navis GJ. Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrol Dial Transplant. 2014;1563:70

9 Publicaties Nefrologie 2014 Pagina Smink PA, Miao Y, Eijkemans MJ, Bakker SJL, Raz I, Parving HH, Hoekman J, Grobbee DE, Zeeuw D de, Lambers Heerspink HJ. The importance of short-term off-target effects in estimating the long-ter renal and cardiovascular protection of angiotensin receptor blockers. Clin Pharmacol Ther. 2014;95: Snijder PM, Frenay AR, Koning AM, Bachtler M, Pasch A, Kwakernaak AJ, Berg E van den, Bos EM, Hillebrands JL, Navis GJ, Leuvenink HG, Goor H van. Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage. Nitric Oxide. 2014;42: Souza AW de, Leeuw K de, Timmeren MM van, Limburg PC, Stegeman CA, Bijl M, Westra J, Kallenberg CGM. Impact of serum high mobility group box 1 and soluble receptor for advanced glycation end-products on subclinical atherosclerosis in patients with granulomatosis with polyangiitis. PLoS One. 2014;9:e Souza AW de, Abdulahad WH, Sosicka P, Bijzet J, Limburg PC, Stegeman CA, Bijl M, Westra J, Kallenberg CGM. Are urinary levels of high mobility group box 1 markers of active nephritis antineutrophil cytoplasmic antibody - associated vasculitis? Clin Exp Immunol. 2014;178: Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Abad JM, Aresté N, de la Torre RA, Caskey F, Couchoud C, Finne P, Heaf J, Hoitsma A, de Meester J, Pascual J, Postorino M, Ravani P, Zurriaga O, Jager KJ, Gansevoort RT; ERA-EDTA Registry; EuroCYST Consortium; WGIKD. Renal replacement therapy for autosomal dominant polycystic kidney disease (ADPKD) in Europe: prevalence and survival--an analysis of data from the ERA-EDTA Registry. Nephrol Dial Transplant Sep;29 Suppl 4;iv Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Caskey F, Collart F, Finne P, Fogarty DG, Groothoff JW, Hoitsma A, Nogier MB, Postorino M, Ravani P, Zurriaga O, Jager KJ, Gansevoort RT; on behalf of the ERA-EDTA Registry; EuroCYST Consortium; the WGIKD. Analysis of data from the ERA-EDTA Registry indicates that conventional treatments for chronic kidney disease do not reduce the need for renal replacement therapy in autosomal dominant polycystic kidney disease. Kidney Int. 2014;86: Stamellou E, Storz D, Botov S, Ntasis E, Wedel J, Sollazzo S, Krämer BK, Son WJ van, Seelen MAJ, Schmalz HG, Schmidt A, Hafner M, Yard BA. Different design of enzyme-triggered COreleasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation. Redox Biol. 2014;;2: Teunissen-Beekman KF, Dopheide J, Geleijnse JM, Bakker SJL, Brink EJ, Leeuw PW de, Serroyen J, Baak MA van. Differential effects of proteins and carbohydrates on postprandial blood pressure-related responses. Br J Nutr. 2014;112: Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N et al including Gansevoort RT. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J HumGenet. 2014;94: Turin TC, Matsushita K, Coresh J, Arima H, Chadban SJ, Cirillo M et al including Jong PE de, Gansevoort RT. Ckd epidemiology. Nephrol Dial Transplant. 2014;29 Suppl 3:iii54-iii Turin TC, Ahmed SB, Tonelli M, Manns B, Ravani P, James M, Quinn RR, Jun M, Gansevoort RT, Hemmelgarn B. Kidney function, albuminuria and life expectancy. Can J Kidney Health Dis. 2014;1: Valente MA, Hillege HL, Navis GJ, Voors AA, Dunselman PH, Veldhuisen DJ van, Damman K. The Chronic Kidney Disease Epidemiology Collaboration equation outperforms the modification of diet in renal disease equation for estimating glomerular filtration rate in chronic systolic heart failure. Eur J Heart Fail. 2014;16: Vart P, Bakker SJL, Schöttker B, Zeeuw D de, Rothenbacher D, Brenner H, Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort RT. Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort. Clin Chem Lab Med. 2014;Nov 21. [Epub]

10 Publicaties Nefrologie 2014 Pagina Verbeek DE, Waanders F, Mulder AB, Bierman WF, Croles FN. Quiz page may 2014: acute kidney injury with red urine. Am J Kidney Dis. 2014;63:A Vimaleswaran KS, Cavadino A, Berry DJ; LifeLines Cohort Study investigators including Navis GJ et al; International Consortium for Blood Pressure (ICBP); Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium; Global Blood Pressure Genetics (Global BPGen) consortium including Borst MH de; Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. Lancet Diabetes Endocrinol. 2014;2: Volgina G, Gadzhikulieva M, Uyshuk N, Kawamura E, Hisano S, Nakashima H et al including Son WJ van, Sanders JSF. Renal histopathology. Nephrol Dial Transplant. 2014;29 Suppl 3:iii451-iii Voors AA, Dahlke M, Meyer S, Stepinska J, Gottlieb SS, Jones A, Zhang Y,Laurent D, Slart RH, Navis GJ. Renal hemodynamic effects of serelaxin in patients with chronic heart failure: A randomized, Placebo-controlled study. Circ Heart Fail. 2014;7: Vusse ML van der, Son WJ van, Ott A, Manson W. Helicobacter canis bacteremia in a renal transplant patient. Transpl Infect Dis. 2014;16: Walsh M, Faurschou M, Berden A, Flossmann O, Bajema I, Hoglund P et al. European Vasculitis Study Group including collaborators Stegeman CA et al. Long-term follow-up of cyclophosphamide compared with azathioprine for initial maintenance therapy in ANCAassociated vasculitis. Clin J Am Soc Nephrol. 2014;5;9: Wen CP, Matsushita K, Coresh J, Iseki K, Islam M, Katz R, McClellan W, Peralta CA, Wang H, Zeeuw D de, Astor BC, Gansevoort RT, Levey AS, Levin A. Chronic Kidney Disease Prognosis Consortium including collaborators Bakker SJL, Jong PE de et al. Relative risks of chronic kidney disease; for mortality and end-stage renal disease across races are similar. Kidney Int. 2014;86: Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Mägi R, Ferreira T, Fall T, Graff M, Justice AE, Luan J, Gustafsson S, Randall JC, Vedantam S, Workalemahu T, Kilpeläinen TO, Scherag A, Esko T, Kutalik Z, Heid IM, Loos RJ; Genetic Investigation of Anthropometric Traits (GIANT) Consortium including collaborators Bakker SJL, Navis GJ et al. Quality control and conduct of genome-wide association meta-analyses. Nat Protoc. 2014;9: Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, et al, including Navis GJ, Gansevoort RT, Bakker SJL. Electronic Medical Records and Genomics (emerge) Consortium; MIGen Consortium; PAGE Consortium; LifeLines Cohort Study. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014;46: Yazdani S, Navis GJ, Hillebrands JL, Goor H van, Born van den J. Lymphangiogenesis in renal diseases: passive bystander or active participant? Expert Rev Mol Med. 2014;16:e Zaferani A, Talsma D, Richter MK, Daha MR, Navis GJ, Seelen MAJ, Born J van den. Heparin/heparan sulphate interactions with complement--a possible target for reduction of renal function loss? Nephrol Dial Transplant. 2014;29: Zaferani A, Talsma DT, Yazdani S, Celie JW, Aikio M, Heljasvaara R, Navis GJ, Pihlajaniemi T, Born J van den. Basement membrane zone collagens XV and XVIII/proteoglycans mediate leukocyte influx in renal ischemia/reperfusion. PLoS One. 2014;9:e Zittema D, Berg E van den, Meijer E, Boertien WE, Muller Kobold AC, Franssen CFM, Jong PE de, Bakker SJL, Navis GJ, Gansevoort RT. Kidney function and plasma copeptin levels in healthy kidney donors and autosomal dominant polycystic kidney disease patients. Clin J Am Soc Nephrol. 2014;9:

11 Publicaties Nefrologie 2014 Pagina DISSERSATIES Kwakernaak AJ Pathophysiological aspects of lifestyle and the kidney Promtor: prof dr GJ Navis Co-promotores: dr RPF Dullaart, dr MH Hemmelder, dr GD Laverman Rijksuniversiteit Groningen, Faculteit der Medische Wetenschappen Groningen, Boertien WE Vasopressin in chronic kidney disease and its effects in autosomal dominant polycystic kidney disease Promotor: prof dr PE de Jong Co-promotor: dr RT Gansevoort Rijksuniversiteit Groningen, Faculteit der Medische Wetenschappen Groningen, Joosten JMH Defining risk factors associated with renal and cognitive dysfunction Promotores: prof dr HJG Bilo, prof dr JPJ Slaets Co-promotores: dr RT Gansevoort, dr GJ Izaks Rijksuniversiteit Groningen, Faculteit der Medische Wetenschappen Groningen, Assa S Hemodialysis-induced left ventricular dysfunction Promotores: prof dr PE de Jong, prof dr AA Voors Co-promotores: dr CFM Franssen Rijksuniversiteit Groningen, Faculteit der Medische Wetenschappen Groningen, Scheven L Novel aspects regarding mechanisms and consequences of albuminuria Promotor: prof dr PE de Jong Co-promotores: dr RT Gansevoort Rijksuniversiteit Groningen, Faculteit der Medische Wetenschappen Groningen, HOOFDSTUK BOEK -

Victims Compensation Claim Status of All Pending Claims and Claims Decided Within the Last Three Years

Victims Compensation Claim Status of All Pending Claims and Claims Decided Within the Last Three Years Claim#:021914-174 Initials: J.T. Last4SSN: 6996 DOB: 5/3/1970 Crime Date: 4/30/2013 Status: Claim is currently under review. Decision expected within 7 days Claim#:041715-334 Initials: M.S. Last4SSN: 2957

More information

PUBLICATIES NEFROLOGIE 2013 Pagina 1 19 6 2014

PUBLICATIES NEFROLOGIE 2013 Pagina 1 19 6 2014 PUBLICATIES NEFROLOGIE 2013 Pagina 1 19 6 2014 1. Abbasi A, Corpeleijn E, Gansevoort RT, Gans ROB, Hillege HL, Stolk RP, Navis GJ, Bakker SJL, Dullaart RPF. Role of HDL cholesterol and estimates of HDL

More information

PUBLICATIES NEFROLOGIE 2012

PUBLICATIES NEFROLOGIE 2012 PUBLICATIES NEFROLOGIE 2012 1. Abbasi A, Corpeleijn E, Peelen LM, Gansevoort RT, Jong PE de, Gans ROB, Rathmann W, Kowall B, Meisinger C, Hillege HL, Stolk RP, Navis GJ, Beulens JW, Bakker SJL. External

More information

Elective Project Report

Elective Project Report Elective Project Report I spent my elective at The Royal Free Hospital, London doing renal medicine. I decided to undertake my elective in renal medicine for two reasons: 1) I am very interested in this

More information

Using multiple biomarkers to predict renal and cardiovascular drug efficacy: Implications for drug development and registration

Using multiple biomarkers to predict renal and cardiovascular drug efficacy: Implications for drug development and registration Using multiple biomarkers to predict renal and cardiovascular drug efficacy: Implications for drug development and registration Hiddo Lambers Heerspink Department of Clinical Pharmacology University Medical

More information

PROCEEDINGS DIABETIC NEPHROPATHY: DETECTION AND TREATMENT OF RENAL DISEASE IN PATIENTS WITH DIABETES* Jiten Vora, MA, MD, FRCP ABSTRACT

PROCEEDINGS DIABETIC NEPHROPATHY: DETECTION AND TREATMENT OF RENAL DISEASE IN PATIENTS WITH DIABETES* Jiten Vora, MA, MD, FRCP ABSTRACT DIABETIC NEPHROPATHY: DETECTION AND TREATMENT OF RENAL DISEASE IN PATIENTS WITH DIABETES* Jiten Vora, MA, MD, FRCP ABSTRACT Diabetic nephropathy affects people with either type 1 or type 2 diabetes mellitus.

More information

Can Common Blood Pressure Medications Cause Diabetes?

Can Common Blood Pressure Medications Cause Diabetes? Can Common Blood Pressure Medications Cause Diabetes? By Nieske Zabriskie, ND High blood pressure, or hypertension, is a major risk factor for cardiovascular disease. In the United States, approximately

More information

Small artery tone under control of the endothelium

Small artery tone under control of the endothelium Small artery tone under control of the endothelium On the importance of EDHF and myogenic tone in organ (dys)function Simone K. Gschwend Publication of this thesis was supported by generous contributions

More information

Nierfunctiemeting en follow-up van chronisch nierlijden

Nierfunctiemeting en follow-up van chronisch nierlijden Nierfunctiemeting en follow-up van chronisch nierlijden 12 Jan 2016 Patrick Peeters, M.D. Dept Nephrology Ghent University Hospital Plan of presentation 1/ Renal function determination: Measured GFR Estimated

More information

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD

DISCLOSURES RISK ASSESSMENT. Stroke and Heart Disease -Is there a Link Beyond Risk Factors? Daniel Lackland, MD STROKE AND HEART DISEASE IS THERE A LINK BEYOND RISK FACTORS? D AN IE L T. L AC K L AN D DISCLOSURES Member of NHLBI Risk Assessment Workgroup RISK ASSESSMENT Count major risk factors For patients with

More information

Drug Treatment in Type 2 Diabetes with Hypertension

Drug Treatment in Type 2 Diabetes with Hypertension Hypertension is 1.5 2 times more prevalent in Type 2 diabetes (prevalence up to 80 % in diabetic subjects). This exacerbates the risk of cardiovascular disease by ~ two-fold. Drug therapy reduces the risk

More information

ESCMID Online Lecture Library. by author

ESCMID Online Lecture Library. by author Do statins improve outcomes of patients with sepsis and pneumonia? Jordi Carratalà Department of Infectious Diseases Statins for sepsis & community-acquired pneumonia Sepsis and CAP are major healthcare

More information

Microalbuminuria: An increasingly recognized risk factor for CVD

Microalbuminuria: An increasingly recognized risk factor for CVD Microalbuminuria: An increasingly recognized risk factor for CVD Long known to be associated with kidney disease, the importance of protein in the urine is now becoming recognized as a sensitive, accessible

More information

Prevalence and risk factor of chronic kidney disease in elderly diabetic patients in Korea 성애병원 내과 김정한

Prevalence and risk factor of chronic kidney disease in elderly diabetic patients in Korea 성애병원 내과 김정한 Prevalence and risk factor of chronic kidney disease in elderly diabetic patients in Korea 성애병원 내과 김정한 Introduction CKD의 정의와 egfr의 측정 CKD의 risk factor와 mechanism 한국의 CKD prevalence 와 prognosis CKD의 치료와

More information

Metabolic Syndrome Overview: Easy Living, Bitter Harvest. Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007

Metabolic Syndrome Overview: Easy Living, Bitter Harvest. Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007 Metabolic Syndrome Overview: Easy Living, Bitter Harvest Sabrina Gill MD MPH FRCPC Caroline Stigant MD FRCPC BC Nephrology Days, October 2007 Evolution of Metabolic Syndrome 1923: Kylin describes clustering

More information

25-hydroxyvitamin D: from bone and mineral to general health marker

25-hydroxyvitamin D: from bone and mineral to general health marker DIABETES 25 OH Vitamin D TOTAL Assay 25-hydroxyvitamin D: from bone and mineral to general health marker FOR OUTSIDE THE US AND CANADA ONLY Vitamin D Receptors Brain Heart Breast Colon Pancreas Prostate

More information

Prescription Pattern of Anti Hypertensive Drugs used in Hypertensive Patients with Associated Type2 Diabetes Mellitus in A Tertiary Care Hospital

Prescription Pattern of Anti Hypertensive Drugs used in Hypertensive Patients with Associated Type2 Diabetes Mellitus in A Tertiary Care Hospital Research Article Prescription Pattern of Anti Hypertensive Drugs used in Hypertensive Patients with Associated Type2 Diabetes Mellitus in A Tertiary Care Hospital *T. JANAGAN 1, R. KAVITHA 1, S. A. SRIDEVI

More information

Vitamin D und seine Bedeutung im Immunsystem und bei der Infektabwehr

Vitamin D und seine Bedeutung im Immunsystem und bei der Infektabwehr Vitamin D und seine Bedeutung im Immunsystem und bei der Infektabwehr Stefan Pilz Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Austria Department

More information

GUIDELINES FOR THE TREATMENT OF DIABETIC NEPHROPATHY*

GUIDELINES FOR THE TREATMENT OF DIABETIC NEPHROPATHY* 71 GUIDELINES FOR THE TREATMENT OF DIABETIC NEPHROPATHY* Ryuichi KIKKAWA** Asian Med. J. 44(2): 71 75, 2001 Abstract: Diabetic nephropathy is the most devastating complication of diabetes and is now the

More information

World Kidney Day 11 March 2010: we must act on diabetic kidney disease

World Kidney Day 11 March 2010: we must act on diabetic kidney disease November 11, 2009 Diabetic kidney disease: Act now or pay later Robert C Atkins and Paul Zimmet For the 2010 International Society of Nephrology/International Federation of Kidney Foundations World Kidney

More information

HYPERTENSION ASSOCIATED WITH RENAL DISEASES

HYPERTENSION ASSOCIATED WITH RENAL DISEASES RENAL DISEASE v Patients with renal insufficiency should be encouraged to reduce dietary salt and protein intake. v Target blood pressure is less than 135-130/85 mmhg. If patients have urinary protein

More information

Update in Contrast Induced Nephropathy

Update in Contrast Induced Nephropathy Update in Contrast Induced Nephropathy Yves Pirson Service de Néphrologie, Clin. Univ. St-Luc - UCL A 76-year-old man with - type 2 diabetes - CKD (ser. creat.: 1.8 mg/dl; GFR: 32) presents with angina

More information

In many diabetes units, people with type

In many diabetes units, people with type Renal Microalbuminuria: Screening and management in type 2 diabetes Julia Arundale Introduction In many diabetes units, patients with type 1 or type 2 diabetes are screened for proteinuria. Screening for

More information

( Diabetic nephropathy) ( Microalbuminuria ) ( Macroalbuminuria )

( Diabetic nephropathy) ( Microalbuminuria ) ( Macroalbuminuria ) 2006 17 99-105 2006 20-40% ( ESRD ) 30 299 mg ( ) ( 300 mgday ) DCCBs ) dihydropyridine calcium channel blockers ( non- DCCBs ( -blockers ( diuretics ) 10%) 0.8 ( 60 mlmin per 1.73 m 2 30 mlmin per 1.73

More information

Definition, Prevalence, Pathophysiology and Complications of CKD. JM Krzesinski CHU Liège-ULg Core curriculum Nephrology September 28 th 2013

Definition, Prevalence, Pathophysiology and Complications of CKD. JM Krzesinski CHU Liège-ULg Core curriculum Nephrology September 28 th 2013 Definition, Prevalence, Pathophysiology and Complications of CKD JM Krzesinski CHU Liège-ULg Core curriculum Nephrology September 28 th 2013 KI supplements January 2013 Objectives of the course on CKD:

More information

Guideline for Microalbuminuria Screening

Guideline for Microalbuminuria Screening East Lancashire Diabetes Network Guideline for Microalbuminuria Screening Produced by: Task and Finish Group, Clinical Standards Group Produced: August 2006 Approved by: East Lancashire Diabetes Network

More information

Your Life Your Health Cariodmetabolic Risk Syndrome Part VII Inflammation chronic, low-grade By James L. Holly, MD The Examiner January 25, 2007

Your Life Your Health Cariodmetabolic Risk Syndrome Part VII Inflammation chronic, low-grade By James L. Holly, MD The Examiner January 25, 2007 Your Life Your Health Cariodmetabolic Risk Syndrome Part VII Inflammation chronic, low-grade By James L. Holly, MD The Examiner January 25, 2007 The cardiometabolic risk syndrome is increasingly recognized

More information

Microalbuminuria: We are in the midst of an epidemic: the epidemic. So What s a Little Protein? Malcolm s diabetes. How much is too much?

Microalbuminuria: We are in the midst of an epidemic: the epidemic. So What s a Little Protein? Malcolm s diabetes. How much is too much? Focus on CME at the University of Saskatchewan Microalbuminuria: So What s a Little Protein? By Judith T. Klassen, BSc, MD, FRCPC University of Saskatchewan Practical Management of Common Medical Problems

More information

Guidance for Industry Diabetes Mellitus Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes

Guidance for Industry Diabetes Mellitus Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes Guidance for Industry Diabetes Mellitus Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes U.S. Department of Health and Human Services Food and Drug Administration Center

More information

Prediction of Kidney Disease Progression in Patients with Diabetes

Prediction of Kidney Disease Progression in Patients with Diabetes Prediction of Kidney Disease Progression in Patients with Diabetes John Arthur, MD, PhD Medical University of South Carolina SEKDC Meeting September 8, 2012 Objectives Understand the importance of predicting

More information

Men Sexual Dysfunction Associated with Obesity and Metabolic Syndrome

Men Sexual Dysfunction Associated with Obesity and Metabolic Syndrome Men Sexual Dysfunction Associated with Obesity and Metabolic Syndrome By Aly A. Abbassy, MD, FACE Professor of Medicine (Endocrinology) Alexandria University My Talk will include: 1-Types of Men sexual

More information

Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus

Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus Agency for Healthcare Research and Quality Evidence Report/Technology Assessment Number 84 Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus Summary Overview Clinical

More information

Diabetic nephropathy is detected clinically by the presence of persistent microalbuminuria or proteinuria.

Diabetic nephropathy is detected clinically by the presence of persistent microalbuminuria or proteinuria. Kidney Complications Diabetic Nephropathy Diabetic nephropathy is detected clinically by the presence of persistent microalbuminuria or proteinuria. The peak incidence of nephropathy is usually 15-25 years

More information

How To Know If Low Protein Diet Is Beneficial For Kidney Health

How To Know If Low Protein Diet Is Beneficial For Kidney Health Protein Intake and Diabetic Kidney Disease Robert C. Stanton Joslin Diabetes Center 1/Serum Creatinine Plot Low Protein Protects in Renal Ablation Model 24% Protein Diet 6% Protein Diet Right Nephrectomy

More information

Dose-Response Effects of Sodium Intake on Blood Pressure

Dose-Response Effects of Sodium Intake on Blood Pressure I Dose-Response Effects of Sodium Intake on 1 +2 NS +1 NS -2 NS +5 NS 0.46 (20) 4.6 () 25.9 (1128) FIGURE I-1 Blood pressure (mm Hg) according to dietary sodium intake in g/d (mmol/d) among 8 normotensive

More information

Understanding diabetes Do the recent trials help?

Understanding diabetes Do the recent trials help? Understanding diabetes Do the recent trials help? Dr Geoffrey Robb Consultant Physician and Diabetologist CMO RGA UK Services and Partnership Assurance AMUS 25 th March 2010 The security of experience.

More information

Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results

Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results Systolic Blood Pressure Intervention Trial (SPRINT) Principal Results Paul K. Whelton, MB, MD, MSc Chair, SPRINT Steering Committee Tulane University School of Public Health and Tropical Medicine, and

More information

The WHI 12 Years Later: What Have We Learned about Postmenopausal HRT?

The WHI 12 Years Later: What Have We Learned about Postmenopausal HRT? AACE 23 rd Annual Scientific and Clinical Congress (2014) Syllabus Materials: The WHI 12 Years Later: What Have We Learned about Postmenopausal HRT? JoAnn E. Manson, MD, DrPH, FACP, FACE Chief, Division

More information

Package nephro. February 23, 2015

Package nephro. February 23, 2015 Type Pack Title Biostatistics Utilities for Nephrology Version 1.1 Date 2015-01-31 Author Pack nephro February 23, 2015 Maintainer Set of functions to estimate the Glomerular

More information

C-Reactive Protein and Diabetes: proving a negative, for a change?

C-Reactive Protein and Diabetes: proving a negative, for a change? C-Reactive Protein and Diabetes: proving a negative, for a change? Eric Brunner PhD FFPH Reader in Epidemiology and Public Health MRC Centre for Causal Analyses in Translational Epidemiology 2 March 2009

More information

How To Know If You Have Microalbuminuria

How To Know If You Have Microalbuminuria 3 PREVALENCE AND PREDICTORS OF MICROALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A CROSS-SECTIONAL OBSERVATIONAL STUDY Dr Ashok S Goswami *, Dr Janardan V Bhatt**; Dr Hitesh Patel *** *Associate

More information

The sensitive marker for glomerular filtration rate (GFR) Estimation of GFR from Serum Cystatin C:

The sensitive marker for glomerular filtration rate (GFR) Estimation of GFR from Serum Cystatin C: The sensitive marker for glomerular filtration rate (GFR) Estimation of GFR from Serum Cystatin C: The good correlation allows close estimation of GFR Cystatin C GFR GFR in serum estimated* measured* n

More information

KIDNEY FUNCTION RELATION TO SIZE OF THE TUMOR IN RENAL CELL CANCINOMA

KIDNEY FUNCTION RELATION TO SIZE OF THE TUMOR IN RENAL CELL CANCINOMA KIDNEY FUNCTION RELATION TO SIZE OF THE TUMOR IN RENAL CELL CANCINOMA O.E. Stakhvoskyi, E.O. Stakhovsky, Y.V. Vitruk, O.A. Voylenko, P.S. Vukalovich, V.A. Kotov, O.M. Gavriluk National Canсer Institute,

More information

Psoriasis Co-morbidities: Changing Clinical Practice. Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology. Psoriatic Arthritis

Psoriasis Co-morbidities: Changing Clinical Practice. Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology. Psoriatic Arthritis Psoriasis Co-morbidities: Changing Clinical Practice Theresa Schroeder Devere, MD Assistant Professor, OHSU Dermatology Psoriatic Arthritis Psoriatic Arthritis! 11-31% of patients with psoriasis have psoriatic

More information

Version 1 2015. Module guide. Preliminary document. International Master Program Cardiovascular Science University of Göttingen

Version 1 2015. Module guide. Preliminary document. International Master Program Cardiovascular Science University of Göttingen Version 1 2015 Module guide International Master Program Cardiovascular Science University of Göttingen Part 1 Theoretical modules Synopsis The Master program Cardiovascular Science contains four theoretical

More information

Second- and Third-Line Approaches for Type 2 Diabetes Workgroup: Topic Brief

Second- and Third-Line Approaches for Type 2 Diabetes Workgroup: Topic Brief Second- and Third-Line Approaches for Type 2 Diabetes Workgroup: Topic Brief March 7, 2016 Session Objective: The objective of this workshop is to assess the value of undertaking comparative effectiveness

More information

嘉 義 長 庚 醫 院 藥 劑 科 Speaker : 翁 玟 雯

嘉 義 長 庚 醫 院 藥 劑 科 Speaker : 翁 玟 雯 The Clinical Efficacy and Safety of Sodium Glucose Cotransporter-2 (SGLT2) Inhibitors in Adults with Type 2 Diabetes Mellitus 嘉 義 長 庚 醫 院 藥 劑 科 Speaker : 翁 玟 雯 Diabetes Mellitus : A group of diseases characterized

More information

KDIGO THE GEORGE INSTITUTE FOR GLOBAL HEALTH. Antiocoagulation in diabetes and CKD Vlado Perkovic

KDIGO THE GEORGE INSTITUTE FOR GLOBAL HEALTH. Antiocoagulation in diabetes and CKD Vlado Perkovic THE GEORGE INSTITUTE FOR GLOBAL HEALTH Antiocoagulation in diabetes and CKD Vlado Perkovic Executive Director, George Institute Australia Professor of Medicine, University of Sydney Affiliated with the

More information

Albumin and All-Cause Mortality Risk in Insurance Applicants

Albumin and All-Cause Mortality Risk in Insurance Applicants Copyright E 2010 Journal of Insurance Medicine J Insur Med 2010;42:11 17 MORTALITY Albumin and All-Cause Mortality Risk in Insurance Applicants Michael Fulks, MD; Robert L. Stout, PhD; Vera F. Dolan, MSPH

More information

How To Know If Coffee Increases Type 2 Diabetes Risk

How To Know If Coffee Increases Type 2 Diabetes Risk help in type 2 diabetes risk reduction? 14th November 2013 Contents Page 1 Introduction 2 2 Epidemiological evidence 3 3 Clinical intervention trials 4 4 Clinical parameters 5 5 Underlying mechanisms 6

More information

Improving cardiometabolic health in Major Mental Illness

Improving cardiometabolic health in Major Mental Illness Improving cardiometabolic health in Major Mental Illness Dr. Adrian Heald Consultant in Endocrinology and Diabetes Leighton Hospital, Crewe and Macclesfield Research Fellow, Manchester University Metabolic

More information

Overview of Diabetes Management. By Cindy Daversa, M.S.,R.D.,C.D.E. UCI Health

Overview of Diabetes Management. By Cindy Daversa, M.S.,R.D.,C.D.E. UCI Health Overview of Diabetes Management By Cindy Daversa, M.S.,R.D.,C.D.E. UCI Health Objectives: Describe the pathophysiology of diabetes. From a multiorgan systems viewpoint. Identify the types of diabetes.

More information

TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION. Robert Dobbins, M.D. Ph.D.

TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION. Robert Dobbins, M.D. Ph.D. TYPE 2 DIABETES MELLITUS: NEW HOPE FOR PREVENTION Robert Dobbins, M.D. Ph.D. Learning Objectives Recognize current trends in the prevalence of type 2 diabetes. Learn differences between type 1 and type

More information

GFR (Glomerular Filtration Rate) A Key to Understanding How Well Your Kidneys Are Working

GFR (Glomerular Filtration Rate) A Key to Understanding How Well Your Kidneys Are Working GFR (Glomerular Filtration Rate) A Key to Understanding How Well Your Kidneys Are Working www.kidney.org National Kidney Foundation's Kidney Disease Outcomes Quality Initiative Did you know that the National

More information

Introduction. Pathogenesis of type 2 diabetes

Introduction. Pathogenesis of type 2 diabetes Introduction Type 2 diabetes mellitus (t2dm) is the most prevalent form of diabetes worldwide. It is characterised by high fasting and high postprandial blood glucose concentrations (hyperglycemia). Chronic

More information

Registered Charity No: 326679 Caring for those with a rare, complex and lifelong disease www.behcets.org.uk

Registered Charity No: 326679 Caring for those with a rare, complex and lifelong disease www.behcets.org.uk Registered Charity No: 326679 Caring for those with a rare, complex and lifelong disease www.behcets.org.uk Behçet s Disease and the Kidneys How are the kidneys affected by Behçet s disease? Kidney disease

More information

CHRONIC KIDNEY DISEASE MANAGEMENT GUIDE

CHRONIC KIDNEY DISEASE MANAGEMENT GUIDE CHRONIC KIDNEY DISEASE MANAGEMENT GUIDE Outline I. Introduction II. Identifying Members with Kidney Disease III. Clinical Guidelines for Kidney Disease A. Chronic Kidney Disease B. End Stage Renal Disease

More information

Supplements, Vitamin D, Omega-3 Fatty Acids, and Co-Enzyme Q10: What Really Works?

Supplements, Vitamin D, Omega-3 Fatty Acids, and Co-Enzyme Q10: What Really Works? Supplements, Vitamin D, Omega-3 Fatty Acids, and Co-Enzyme Q10: What Really Works? DAVID P. GOWMAN, D.O. S E C T I O N CHIEF, CARDIOLOGY P R O G R A M D I R E C T O R, CARDIOLOGY F E L L O W S H I P B

More information

Which drugs should be used to treat diabetes in cirrhotic patients?

Which drugs should be used to treat diabetes in cirrhotic patients? Which drugs should be used to treat diabetes in cirrhotic patients? Frankfurt am Main 10-12 September 2015 Jörg Bojunga Medizinische Klinik I Johann Wolfgang Goethe-Universität Frankfurt am Main Significance

More information

Summary HTA. HTA-Report Summary. Introduction

Summary HTA. HTA-Report Summary. Introduction Summary HTA HTA-Report Summary Antioxidative vitamines for prevention of cardiovascular disease for patients after renal transplantation and patients with chronic renal failure Schnell-Inderst P, Kossmann

More information

Chronic Kidney Disease and the Electronic Health Record. Duaine Murphree, MD Sarah M. Thelen, MD

Chronic Kidney Disease and the Electronic Health Record. Duaine Murphree, MD Sarah M. Thelen, MD Chronic Kidney Disease and the Electronic Health Record Duaine Murphree, MD Sarah M. Thelen, MD Definition of Chronic Kidney Disease (CKD) Defined by the National Kidney Foundation Either a decline in

More information

How To Prevent Type 2 Diabetes

How To Prevent Type 2 Diabetes Introduction The Primary Prevention of Type 2 Diabetes AADE Practice Synopsis Issued December 1, 2014 The prevalence of type 2 diabetes is reaching epidemic proportions with more than 9.3% of adults in

More information

How To Determine The Prevalence Of Microalbuminuria

How To Determine The Prevalence Of Microalbuminuria Research Journal of Pharmaceutical, Biological and Chemical Sciences Prevalence of Microalbuminuria in relation to HbA1c among known Type2 Diabetic Patients in Puducherry population Muraliswaran P 1 *,

More information

Cardiac Rehabilitation The Best Medicine for Your CAD Patients. James A. Stone

Cardiac Rehabilitation The Best Medicine for Your CAD Patients. James A. Stone James A. Stone BPHE, BA, MSc, MD, PhD, FRCPC, FAACVPR, FACC Clinical Professor of Medicine, University of Calgary Total Cardiology, Calgary Acknowledgements and Disclosures Acknowledgements Jacques Genest

More information

Cardiovascular Disease Risk Factors Part XII Insulin Resistance By James L. Holly, MD Your Life Your Health The Examiner September 15, 2005

Cardiovascular Disease Risk Factors Part XII Insulin Resistance By James L. Holly, MD Your Life Your Health The Examiner September 15, 2005 Cardiovascular Disease Risk Factors Part XII By James L. Holly, MD Your Life Your Health The Examiner September 15, 2005 As we approach the end of our extended series on cardiovascular disease risk factors,

More information

Natalia Taborda Vanegas. Doc. Sci. Student Immunovirology Group Universidad de Antioquia

Natalia Taborda Vanegas. Doc. Sci. Student Immunovirology Group Universidad de Antioquia Pathogenesis of Dengue Natalia Taborda Vanegas Doc. Sci. Student Immunovirology Group Universidad de Antioquia Infection process Epidermis keratinocytes Dermis Archives of Medical Research 36 (2005) 425

More information

Hypertension and Diabetes

Hypertension and Diabetes Hypertension and Diabetes C.W. Spellman, D.O., Ph.D., FACOI Professor & Associate Dean Research Dir. Center Diabetes & Metabolic Disorders Texas Tech University Health Science Center Midland-Odessa, Texas

More information

Vascular Effects of Caffeine

Vascular Effects of Caffeine Vascular Effects of Caffeine John P. Higgins MD, MBA, MPHIL, FACC, FACP, FAHA, FACSM, FASNC, FSGC Director of Exercise Physiology Memorial Hermann Sports Medicine Institute Chief of Cardiology, Lyndon

More information

USI Master Policy Information

USI Master Policy Information Policy I.D. Gender A.B. (#327) M 86 United of Omaha $ 1,000,000.00 A.B. (#430) - (#436) M 86 Metlife $ 2,000,000.00 A.G. #1 (#371), (#610), (#624) M Conseco Life $ 3,125,000.00 10/Apr/10 A.G. #2 (#380),

More information

DR. Trinh Thi Kim Hue

DR. Trinh Thi Kim Hue TYPE 2 DIABETES IN THE CHILD AND ADOLESCENT DR. Trinh Thi Kim Hue CONTENTS Definition Diagnosis Treatment Comorbidities and Complications Comorbidities and Complications Screening for T2D References DEFINITION

More information

How To Know If You Have Microalbuminuria

How To Know If You Have Microalbuminuria HIPPOKRATIA 2013, 17, 4: 337-341 ORIGINAL ARTICLE Prevalence of microalbuminuria and risk factor analysis in type 2 diabetes patients in Albania: the need for accurate and early diagnosis of diabetic nephropathy

More information

A list of FDA-approved testosterone products can be found by searching for testosterone at http://www.accessdata.fda.gov/scripts/cder/drugsatfda/.

A list of FDA-approved testosterone products can be found by searching for testosterone at http://www.accessdata.fda.gov/scripts/cder/drugsatfda/. FDA Drug Safety Communication: FDA cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke

More information

Diabetes and the Kidneys

Diabetes and the Kidneys Diabetes and the Kidneys Aim(s) and objective(s) This guideline focuses on the detection, prevention, and management of kidney disease in people with diabetes. The management of end-stage renal disease

More information

VKA in Dialysis: Navigating between Scylla and Charybdis. An De Vriese Nephrology & Infectious Diseases AZ Sint-Jan Brugge

VKA in Dialysis: Navigating between Scylla and Charybdis. An De Vriese Nephrology & Infectious Diseases AZ Sint-Jan Brugge VKA in Dialysis: Navigating between Scylla and Charybdis An De Vriese Nephrology & Infectious Diseases AZ Sint-Jan Brugge AF in Dialysis DOPPS I (1996 2001) and DOPPS II (2002 2004) Wizeman V et al. Kidney

More information

DIABETES AND INSULIN RESISTANCE DIABETES PREVALANCE

DIABETES AND INSULIN RESISTANCE DIABETES PREVALANCE DIABETES AND INSULIN RESISTANCE KARI KOHRS RD LDN CDE UICMC NUTRITION & WELLNESS CENTER DIABETES PREVALANCE Third leading cause of death-- United States 18 million diagnosed Growing at the rate of 3 new

More information

Diabetes, hypertension and a lot more `in the elderly` JORIS SCHAKEL INTERNIST- CLINICAL GERIATRICIAN JGSCHAKEL@SEHOS.CW

Diabetes, hypertension and a lot more `in the elderly` JORIS SCHAKEL INTERNIST- CLINICAL GERIATRICIAN JGSCHAKEL@SEHOS.CW Diabetes, hypertension and a lot more `in the elderly` JORIS SCHAKEL INTERNIST- CLINICAL GERIATRICIAN JGSCHAKEL@SEHOS.CW IT`S HARD TO GIVE GENERAL ADVICE! ``The Elderly`` Heterogeneous group ;widely varying

More information

Aggressive Lowering of Blood Pressure in type 2 Diabetes Mellitus: The Diastolic Cost

Aggressive Lowering of Blood Pressure in type 2 Diabetes Mellitus: The Diastolic Cost Aggressive Lowering of Blood Pressure in type 2 Diabetes Mellitus: The Diastolic Cost Naftali Stern Institute of Endocrinology, Metabolism and Hypertension Tel Aviv -Sourasky Medical Center and Sackler

More information

Jill Malcolm, Karen Moir

Jill Malcolm, Karen Moir Evaluation of Fife- DICE: Type 2 diabetes insulin conversion Article points 1. Fife-DICE is an insulin conversion group education programme. 2. People with greater than 7.5% on maximum oral therapy are

More information

Platelet Function Testing vs Genotyping : Focus on Pharmacogenomics of Clopidogrel. Kiyuk Chang, M.D., Ph.D.

Platelet Function Testing vs Genotyping : Focus on Pharmacogenomics of Clopidogrel. Kiyuk Chang, M.D., Ph.D. Platelet Function Testing vs Genotyping : Focus on Pharmacogenomics of Clopidogrel Kiyuk Chang, M.D., Ph.D. Cardiovascular Center & Cardiology Division Seoul St. Mary s Hospital The Catholic University

More information

20/03/2013. What is it and how did it disappear? What is it and how did it not disappear?

20/03/2013. What is it and how did it disappear? What is it and how did it not disappear? Calcium, phosphor and magnesium: pathophysiology, diagnosis, clinical management S. Van Laecke Ghent University Hospital BVN Core Curriculum Course 2013 What is it and how did it disappear? Miyamoto M

More information

RATE VERSUS RHYTHM CONTROL OF ATRIAL FIBRILLATION: SPECIAL CONSIDERATION IN ELDERLY. Charles Jazra

RATE VERSUS RHYTHM CONTROL OF ATRIAL FIBRILLATION: SPECIAL CONSIDERATION IN ELDERLY. Charles Jazra RATE VERSUS RHYTHM CONTROL OF ATRIAL FIBRILLATION: SPECIAL CONSIDERATION IN ELDERLY Charles Jazra NO CONFLICT OF INTEREST TO DECLARE Relationship Between Atrial Fibrillation and Age Prevalence, percent

More information

In 2002 the National Kidney Foundation s

In 2002 the National Kidney Foundation s VOL xx, NO xx, MONTH 2009 POSITION STATEMENT Definition and Classification of CKD: The Debate Should Be About Patient Prognosis A Position Statement From KDOQI and KDIGO In 2002 the National Kidney Foundation

More information

1.- L a m e j o r o p c ió n e s c l o na r e l d i s co ( s e e x p li c a r á d es p u é s ).

1.- L a m e j o r o p c ió n e s c l o na r e l d i s co ( s e e x p li c a r á d es p u é s ). PROCEDIMIENTO DE RECUPERACION Y COPIAS DE SEGURIDAD DEL CORTAFUEGOS LINUX P ar a p od e r re c u p e ra r nu e s t r o c o rt a f u e go s an t e un d es a s t r e ( r ot u r a d e l di s c o o d e l a

More information

Chronic Kidney Disease and Diabetes

Chronic Kidney Disease and Diabetes Anyone with diabetes can get kidney disease. Diabetes and high blood pressure are the most common causes of kidney disease, and people often have both. Chronic (long term) kidney disease (CKD) caused by

More information

Diabetic Nephropathy

Diabetic Nephropathy Diabetic Nephropathy Kidney disease is common in people affected by diabetes mellitus Definition Urinary albumin excretion of more than 300mg in a 24 hour collection or macroalbuminuria Abnormal renal

More information

COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION

COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE ON THE EVALUATION OF MEDICINAL PRODUCTS FOR CARDIOVASCULAR DISEASE PREVENTION European Medicines Agency Pre-Authorisation Evaluation of Medicines for Human Use London, 25 September 2008 Doc. Ref. EMEA/CHMP/EWP/311890/2007 COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE (CHMP) GUIDELINE

More information

Role of Body Weight Reduction in Obesity-Associated Co-Morbidities

Role of Body Weight Reduction in Obesity-Associated Co-Morbidities Obesity Role of Body Weight Reduction in JMAJ 48(1): 47 1, 2 Hideaki BUJO Professor, Department of Genome Research and Clinical Application (M6) Graduate School of Medicine, Chiba University Abstract:

More information

InDependent Diabetes Trust

InDependent Diabetes Trust InDependent Diabetes Trust Kidneys and Diabetes Updated July 2015 Registered Company Number 3148360 Registered Charity No 1058284 Contents Introduction Healthy Kidneys Kidney disease and diabetes The use

More information

Coordinator of the Brazilian Institute of Health Technology Assessment Coordinator, Hypertension Unit, Division of Cardiology

Coordinator of the Brazilian Institute of Health Technology Assessment Coordinator, Hypertension Unit, Division of Cardiology FLÁVIO DANNI FUCHS Current Administrative and Academic Appointments Administrative Academic Coordinator of the Brazilian Institute of Health Technology Assessment Coordinator, Hypertension Unit, Division

More information

Absolute cardiovascular disease risk assessment

Absolute cardiovascular disease risk assessment Quick reference guide for health professionals Absolute cardiovascular disease risk assessment This quick reference guide is a summary of the key steps involved in assessing absolute cardiovascular risk

More information

Research Skills for Non-Researchers: Using Electronic Health Data and Other Existing Data Resources

Research Skills for Non-Researchers: Using Electronic Health Data and Other Existing Data Resources Research Skills for Non-Researchers: Using Electronic Health Data and Other Existing Data Resources James Floyd, MD, MS Sep 17, 2015 UW Hospital Medicine Faculty Development Program Objectives Become more

More information

William B. Schwartz Division of Nephrology Fellowship Training Program Curriculum

William B. Schwartz Division of Nephrology Fellowship Training Program Curriculum William B. Schwartz Division of Nephrology Fellowship Training Program Curriculum Consult/Transplant Servic Patient Care Take medical history Perform physical examination Urinalysis and sediment eval Interpret

More information

Genetic Epidemiology Core Laboratory

Genetic Epidemiology Core Laboratory 2012 CGM Report Genetic Epidemiology Core Laboratory 卓 越 成 員 Remarkable member Wei J. Chen 陳 為 堅 Professor/ / EDUCATION AND POSITION HELD Bachelor of Medicine, College of Medicine, National Taiwan University,

More information

Internet: Domain Names owned: www.vasc-surgery.com, www.vascsurgeon.com, www.aortasurgery.com

Internet: Domain Names owned: www.vasc-surgery.com, www.vascsurgeon.com, www.aortasurgery.com STEPHEN JOEL MOTEW, MD, FACS Work: Salem Surgical Associates, PA 2915 Lyndhurst Ave. Winston-Salem, NC 27103 (336) 765-5221 Internet: Domain Names owned: www.vasc-surgery.com, www.vascsurgeon.com, www.aortasurgery.com

More information

Albuminuria as a Marker of the Risk of Developing Type 2 Diabetes in Non- Diabetic Aboriginal Australians

Albuminuria as a Marker of the Risk of Developing Type 2 Diabetes in Non- Diabetic Aboriginal Australians Albuminuria as a Marker of the Risk of Developing Type 2 Diabetes in Non- Diabetic Aboriginal Australians Zhiqiang Wang 1 and Wendy E Hoy 1 Centre for Chronic Disease, Department of Medicine, Central Clinical

More information

10. Treatment of peritoneal dialysis associated fungal peritonitis

10. Treatment of peritoneal dialysis associated fungal peritonitis 10. Treatment of peritoneal dialysis associated fungal peritonitis Date written: February 2003 Final submission: July 2004 Guidelines (Include recommendations based on level I or II evidence) The use of

More information

Present and Future of Insulin Therapy: Research Rationale for New Insulins

Present and Future of Insulin Therapy: Research Rationale for New Insulins Present and Future of Insulin Therapy: Research Rationale for New Insulins Current insulin analogues represent an important advance over human insulins, but clinically important limitations of these agents

More information

ASN DIALYSIS ADVISORY GROUP ASN DIALYSIS CURRICULUM

ASN DIALYSIS ADVISORY GROUP ASN DIALYSIS CURRICULUM ASN DIALYSIS ADVISORY GROUP ASN DIALYSIS CURRICULUM Management of Traditional Cardiovascular Risk Factors in ESRD (Hypertension, Dyslipidemia, Glycemic Control) ROBERT D. TOTO, M.D. PROFESSOR OF MEDICINE

More information

DCCT and EDIC: The Diabetes Control and Complications Trial and Follow-up Study

DCCT and EDIC: The Diabetes Control and Complications Trial and Follow-up Study DCCT and EDIC: The Diabetes Control and Complications Trial and Follow-up Study National Diabetes Information Clearinghouse U.S. Department of Health and Human Services NATIONAL INSTITUTES OF HEALTH What

More information

Primary prevention of chronic kidney disease: managing diabetes mellitus to reduce the risk of progression to CKD

Primary prevention of chronic kidney disease: managing diabetes mellitus to reduce the risk of progression to CKD Primary prevention of chronic kidney disease: managing diabetes mellitus to reduce the risk of progression to CKD Date written: July 2012 Author: Kate Wiggins, Graeme Turner, David Johnson GUIDELINES We

More information