MESOTHELIOMA APPLIED RESEARCH FOUNDATION

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1 MESOTHELIOMA APPLIED RESEARCH FOUNDATION Annual Report 2006

2 Board of Directors Chairman Nicholas J. Vogelzang, MD Nevada Cancer Institute Secretary M. Ann Abbe Arlington, Texas Treasurer Ulf Jungnelius, MD Takeda Global Research & Development Mary Cosentino, Esq. Western Springs, IL Michael Harbut, MD, MPH Royal Oak, Michigan Latanyta Manuel Canton, MI Harvey Pass, MD NYU School of Medicine Susan Vento St. Paul, Minnesota In Memoriam Congressman Bruce F. Vento Science Advisory Board Chairman Harvey Pass, MD NYU School of Medicine Steven Albelda, MD University of Pennsylvania Steve Hahn, MD University of Pennsylvania Raffit Hassan, MD National Cancer Institute Hedy Lee Kindler, MD University of Chicago Dan Miller, MD Emory University Lary A. Robinson, MD H. Lee Moffit Cancer Center Victor Roggli, MD Duke University W. Roy Smythe, MD Texas A&M Robert N. Taub, MD Columbia University Joseph R. Testa, PhD Fox Chase Cancer Center Dear Friends, I am honored to be the new Chairperson of the Mesothelioma Applied Research Foundation s Board of Directors. My first meso patients were in 1978 two sisters who had been exposed to asbestos during World War II when they were employed to build liberty ships. I enjoyed getting to know them and was immediately struck by the possibility that genetic influences impacted on asbestos-induced malignancy. Sadly, neither of them had much benefit from the only available drug that we had at that time, doxyrubicin. Today, nearly 30 years later, our knowledge of mesothelioma has advanced dramatically, as have the treatment options. Meso Foundation grants are helping advance the science in critical ways. For example, Meso Foundation-supported researchers Dr. Joseph Testa and Dr. Deborah Altomare at Fox Chase Cancer Center have found that the neurofibromatosis-2 gene is mutated in approximately 50% of meso patients. Why this is etiologic for meso is unclear; but we do know that mutation of the NF2 gene leads to loss of the NF2 protein merlin, which would normally inhibit the ERK signaling that occurs following exposure to asbestos and leads to malignancy. One can now imagine that mutation of the neurofibromatosis gene was the common genetic link leading to meso in the two sisters, and in many other patients. Such detailed scientific hypotheses are now being explored by scientists worldwide, and this is very promising for understanding the meso tumor and developing powerful new treatments to stop it. The Foundation s International Symposium provides these scientists the opportunity to share their results and ideas with each other and with the patient community, and in 2006 we had our 3rd successful meeting. For the first time, the scientific presentations were interpreted for the patients and families. Meanwhile, the International Mesothelioma Interest Group held its meeting right next door, and the scientists enjoyed this additional opportunity for collaborations and interactions. Organizationally, the Foundation continues to be strengthened by the increasing numbers of patients and families who join and support it. My goals include expanding the number of board members to include more patients and families, and I am thrilled to have Mary Cosentino and Latanyta Manuel joining us. We also need to bring in additional expertise in the business and marketing sector, the philanthropic sector and the legal and medical sectors. Our medical advisory board has been strong and continues to be ably led by Dr. Harvey Pass, one of the organization s founders. Dr. Pass will now also serve on the Board of Directors. Given the success of the medical advisory board, we have begun to look toward creating a legal advisory board. Our legal colleagues have a particular interest in meso, representing many of the families involved with the Foundation. The potent triumvirate of patients, physicians and lawyers all focusing on finding better treatments for meso should lead to dramatic synergies not only in fundraising but also in political action. Finally, the fundraising will translate into increased patient education and support and will enable us to continue to build our research grant portfolio. These grants are often the first funding that investigators receive and enable them to achieve longer-term support from the National Cancer Institute or other institutions. A very important step for the Foundation s research grant program is to stimulate true clinical trials. Even though their cost is substantial, this is the only way to translate scientific advances to patients bedsides, and I am confident we can do it. There has been much progress since I first became interested in meso in We have seen the emergence of genetic and molecular knowledge of mesothelioma, and the development of many chemotherapy agents beyond the single drug, doxyrubicin. We now have gemcitabine, Alimta, cisplatin and hopefully soon many other agents. The potent combination of patients, physicians and attorneys as well as philanthropic support from business and the pharmaceutical industry has clearly captured the attention of the federal government. The Foundation and its community of patients and families will continue to be the voice for meso patients in this country and hopefully beyond. I am honored to be part of the family and look forward to serving the Meso Foundation. Eric Vallieres, MD Swedish Cancer Institute Claire Verschraegen, MD University of New Mexico Nicholas Vogelzang, MD Mesothelioma Applied Research Foundation Board Chairman 2

3 New Members Join the Board of Directors Latanyta Manuel s fight against meso began when Andrew Manuel, her husband of 23 years, was diagnosed. Andrew lost his battle to meso on January 23, 2004, but Latanyta continues honoring his memory by helping raise awareness about this devastating disease. In Detroit and urban communities throughout the nation, meso is underdiagnosed, and those patients who are diagnosed do not receive adequate information on their treatment options. Latanyta wants to change this. In addition to her newly added responsibilities as a member of the Meso Foundation s Board of Directors, Latanyta juggles motherhood and extensive involvement with her local community organizations. Latanyta is also a dedicated supporter of education. She sits on the Board of Directors of the Detroit Urban Lutheran School and she teaches Sunday school at her church. Latanyta is a student at Madonna University in Livonia, Michigan, where she is pursuing a double degree in Psychology and Biblical Studies. As a person living with peritoneal mesothelioma, Mary Cosentino brings to the Meso Foundation Board of Directors first-hand knowledge and thorough understanding of all the challenges that patients and their loved ones encounter when faced with mesothelioma. She and her husband Bob also bring a positive, optimistic attitude that meso patients and families truly can make a difference in the disease. Since 2004, Mary and her husband Bob have been devoted Meso Foundation volunteers, financial supporters and political advocates. For over seventeen years Mary has been a member of faculty of law at Loyola University of Chicago, where she still teaches part-time. Last year, with the support of Professor Lawrence Singer, Director of the Beazely Institute for Health Law, Mary developed an independent, directed-research course focusing on legal arguments to increase meso research funding through asbestos litigation and asbestos company bankruptcies. As part of the course, her students were able to attend the 2006 International Symposium on Malignant Mesothelioma. Mary started her legal career in the field of health law as a member of the Legal Department of The Catholic Health Association of the United States, the national trade association for Catholic hospitals and long term care facilities located in St. Louis, Missouri. With experience in both health law and health policy matters, she then joined the Chicago law firm of Gardner, Carton and Douglas and later served as General Counsel to St. Joseph Hospital and Health Care Center in Chicago. Dr. Harvey Pass is recognized both by his patients and by the international medical/scientific community as a visionary leader in meso research and treatment. He has unique passion for meso medicine, from very basic laboratory research all the way through treating patients at their bedsides, and everything in between. Dr. Pass is Professor of Surgery and Chief, Division of Thoracic Surgery and Thoracic Oncology at NYU School of Medicine and Comprehensive Cancer Center. He has studied pleural mesothelioma since 1988; first as Head of Thoracic Oncology and Senior Investigator of the Surgery Branch of the National Cancer Institute in Bethesda and then as Head of Thoracic Oncology at the Karmanos Cancer Institute in Detroit. In 2005, he co-edited Malignant Mesothelioma, the leading research clinical textbook on the disease. While Dr. Pass is new to the Board of Directors, he has served the Foundation since its start in 1999, as Chair of the Science Advisory Board. He has helped design and develop the Foundation s research grants program, helped allocate through that program over $4 million towards critically-needed meso research, co-chaired the Foundation s annual Symposium, and tirelessly lobbied U.S. Senators, the NCI, and the country s largest corporations to make a greater commitment to meso research. Serving on the Board of Directors will create an even greater opportunity for Dr. Pass to apply his zeal for meso patients, and his expert vision for meso research, to the Foundation s strategic agenda. We expect a major impact in all three of the Foundation s program areas directly funding the most important new meso research, educating and supporting meso patients and families, and pushing the federal government to develop a comprehensive and effective meso research program. 3

4 The Foundation s Work Our Mission The Mesothelioma Applied Research Foundation is the national nonprofit collaboration of researchers, physicians, advocates, patients and families dedicated to eradicating mesothelioma (meso) as a life-ending disease. We believe meso can be cured. We believe the resources to support the necessary medical research are available, especially given the human toll of suffering the disease causes, the compassion and energy of the meso community, the moral, legal and economic aspects of asbestos, and the benefits of meso research to the entire cancer research field. We seek to marshal these resources and utilize them responsibly, as effectively as possible and with financial transparency to: Fund the highest quality and most promising meso research projects from around the world through our rigorous peer-review process; Offer sincere support to patients and families by educating them on the disease, helping them to obtain the most up-to-date information on treatment options and connect with meso treatment specialists, and providing them emotional support and community with others; and Raise awareness of meso and advocate that the federal government partner in the effort to cure it by directing an appropriate percentage of our society s resources to the medical research needed to stop this national tragedy Program Highlights Research In 2006, we saw the momentum of meso research and treatment continue to increase. Meso investigators reported significant new understandings of the tumor cell s biology, surgical and drug treatment protocols advanced, a number of clinical trials progressed including the second largest clinical trial ever in meso (SAHA), and important work was completed on meso biomarkers. In fact, as of this writing, the first meso biomarker, MesoMark, has just received FDA approval in the U.S! (See insert.) This great progress was reflected in the success of our 2006 round of grants. We received 33 high quality applications (the most ever), and from these awarded grants to ten excellent new projects. This marks the third year in a row that we have awarded approximately a million dollars of research funding. This substantial, consistent funding for meso is motivating brilliant researchers to invest their careers in meso, and is driving the field forward. At the International Mesothelioma Interest Group s scientific meeting in October (held in tandem with the Foundation s International Symposium), most of the posters and abstracts on new research projects were presented by Foundation-funded investigators. We must continue this funding, and expand it to support larger projects, including clinical trials. Patient Education and Support The 2006 International Symposium on Malignant Mesothelioma was the most successful yet. With the most patients ever, 32, and 170 registrants total, it offered critical patient education about the disease and developing treatments; it also included a strong call to advocacy, and was moving, unity-building, and even at times fun. Last year we unveiled our new website, redesigned to more easily and effectively give meso patients and families the latest and most relevant information about the disease, offer hope and support, and unite the meso community. Almost 400 individuals have now joined the website s meso community which offers important tools including a document archive and bulletin board where patients and families are exchanging information and supporting each other. Personal contact is the heart of our patient education program, and in 2006 we communicated directly by phone or with approximately 600 patients or their family members to provide names of meso medical experts, detailed information on treatment options, or even just a listening ear. Our reward for these efforts is stories like that of peritoneal patient David K. Two years ago, David spoke with Patient Advocacy Director Jill Wayne, telling her that his meso had progressed into both his lungs, and that his doctor said he was inoperable and the prognosis was just weeks to months. Jill recommended he see peritoneal expert Dr. Robert Taub. Today, David s lungs have been successfully treated, and he just told Jill that he is about to undergo Dr. Taub s extensive, and potentially curative, peritoneal treatment protocol! Advocacy Advocating for a serious federal commitment to meso research funding became an even larger Foundation priority in In May, Executive Director Chris Hahn testified before the Senate Defense Appropriations Subcommittee. Chris asked that meso be included among the diseases eligible for research funding from the Department of Defense s $45M Peer Reviewed Medical Research Program. Following an all-out blitz by Foundation researchers, clinicians and grass-roots volunteers, a group of influential Senators backed Chris request, and the Subcommittee included it in the 2007 budget bills report language. Also included was a second year of funding to NIOSH to continue the meso registry and tissue bank instituted as a result of the Foundation s efforts in Unfortunately, Congress 4

5 failed to pass the 2007 budget bill before the 2006 term ended. This very unusual political event left the report language in limbo, so we are continuing to work aggressively to have our language included in the appropriate 2007 funding bill. The credibility the Foundation has gained in Washington D.C. was powerfully demonstrated when the number two ranking Democrat, Senator Dick Durbin, spoke movingly about his commitment to the meso community at the 2006 Symposium s keynote lunch. Senator Harry Reid, who spoke at the first Symposium and has been a strong friend of the meso community for several years, is now the ranking head of the Senate. Senator Durbin is number two. Washington Senator Patty Murray, who for years has been the most vocal federal leader on the need to ban asbestos and provide adequate research funding for meso and other asbestos-related diseases, will be aggressively pushing her bill in We are in the strongest advocacy position for meso ever, and there is much to do! 2006 Fundraising Highlights The Foundation is generously supported by meso patients and their families and loved ones who have invested in the search for a cure, as well as law firms, drug companies, and companies formerly involved with asbestos, all of whom have joined in the common mission of curing the disease was our most successful fundraising year ever, as we received contributions of $2,212,709. Of this, $228,846 came from the annual research funding appeal. This enabled us to award three extra grants on top of the seven for which we were originally budgeted. Attorneys representing meso patients and families made up our largest category of donors, contributing 33% of our total donations by dollar amount. The SimmonsCooper law firm continued to lead by example, donating almost $500,000 over the year. A number of other law firms also donated significant amounts, including several firms which are new donors. It is encouraging that the list of firms giving back and advocating for what patients need most a cure, continues to grow. Right at year end we received a large, and somewhat unexpected, payment of $432,000 from Owens Corning. This represents OC s postasbestos bankruptcy pay-out on the $900,000 over-five-years pledge it made to the Foundation in We believe this is the largest contribution in U.S. history by an asbestos defendant aimed at asbestos disease medical research! Another company formerly involved with asbestos, Owens Illinois, continued its consistent support of the Foundation with a $30,000 gift. Clearly, supporting research through the Foundation to cure the problem is a nonpartisan effort that is in everyone s best interest. We received another first-of-its-kind gift in 2006, when the trustees of the Rutland bankruptcy trust, which was established to pay asbestos claimants, designated the Foundation to receive all excess funds left after all claimants had been identified and paid. As a result we received $137,780. In this way, the trustees served the ultimate interests of all claimants, whose first priority is successful treatment. They also set a concrete precedent for the Foundation s vision that asbestos bankruptcies with their billions in assets, and tens of millions in attorneys fees and other administrative costs are a natural source of funding to cure the fundamental problem, asbestos disease itself. A full 65% of our donors gave in memory of a loved one or friend lost to meso. These gifts ranged from $100,000 and $50,000 gifts to almost a thousand gifts under $500, and constituted 26% of our total contributions by dollar amount. These memorial gifts testify to the loss meso inflicts in our society, and the moving commitment of those who have experienced grave personal loss to help cure the disease for the sake of others. 18% of our gifts, 5% by dollar amount, came directly from meso patients themselves or in honor of a meso patient. We are honored and inspired that meso patients and their friends and loved ones entrust us with their gifts as an investment in their own future. Volunteer events increased from nine in 2005 to 25 in 2006, and raised over $125,000. Patients, family members and friends are finding all kinds of ways to raise awareness and raise funds for research. For 2006, Charity Navigator awarded the Mesothelioma Applied Research Foundation four out of a possible four stars. In earning Charity Navigator s highest rating, the Meso Foundation has demonstrated exceptional financial health, outperforming most of its peers in its efforts to manage and grow its finances in the most fiscally responsible way possible. 5

6 2006 Grant Recipients Dr. Bin Liu, University of California San Francisco Establishing the molecular identity of a panel of internalizing mesothelioma cell surface antigens. Dr. Deborah Altomare, Fox Chase Cancer Center Combinatorial Targeting of Signaling Pathways that are Frequently Implicated in Malignant Mesothelioma Dr. Alla Ivanova, New York University, School of Medicine Mechanisms of innate drug sensitivity in malignant pleural mesotheliomas Dr. Brooke Mossman, University of Vermont & State Agricultural College Nanoporous Spheres for Chemotherapeutic Drug Delivery in Mesothelioma Patients Dr. Courtney Broaddus, University of California, San Francisco The use of novel mesothelioma-specific antibodies for diagnostic and therapeutic preclinical studies. Dr. Stephen Levin, Mount Sinai School of Medicine Serum Specimen Identification and Mortality Experience Update among Asbestos Insulators for Validation of Mesothelioma Biomarkers. Dr. Lee Krug, Memorial Sloan-Kettering Cancer Center WT-1 Analog Peptide Vaccine in Patients with Malignant Mesothelioma Dr. Faris Farassati, University of Minnesota Medical School Silencing Mesothelin: A Novel Approach for Treatment of Mesothelioma Dr. Guang-Hui Xiao, Fox Chase Cancer Center Adenovirus-mediated NK4 gene therapy for malignant mesothelioma Dr. Anil Wali, Wayne State University/Karmanos Cancer Institute The Ubiquitin-Proteasome Pathway in Mesothelioma $1,200,000 $1,000,000 $800,000 Research Funding By Year $600,000 $400,000 $200,

7 Statement of Financial Activity Year ending December 31, 2006 Public Support and Other Income Annual Appeal $328, $228, General Contributions $1,168, $1,688, Symposium Registrations $38, $33, Volunteer Events $133, $131, Sponsorships $305, $307, Grants $26, $18, Investment Gain & Income $62, $49, Total $2,062, $2,457, Expenses Research 68% 65% Grant Funding $962, $1,026, Symposium $206, $173, Education, Support, & Awareness 17% 15% Activities & Materials $189, $194, Symposium $101, $86, Advocacy $151, % $155, % Administration 6% 12% Fundraising $64, $117, Management $42, $105, Total $1,716, $1,858, financial figures are from the Foundation s audited financial statement financial figures are not yet audited. Once available the 2006 audited financial statement will be posted on the Foundation s website. Two-thirds of Symposium expenses are allocated to advancing meso research, and one-third to educating patients/family and community physicians. Donors By Percent of Total Dollar Amount $2,500,000 $2,000,000 Fundraising By Year Plaintiff Law Firms 33% Defendant Corporations 21% $1,500,000 $1,000,000 Individuals 37% Pharmaceutical Companies 3% Bankruptcy Trust 6% $500,

8 Gifts Made In Memory Michael Abbott William Abela Edward Joseph Albarado Louis Allen Lynne Allgaier Gary Anderson James Andrews Paul Antonucci Edgar Mac Arrowood Elmer Asturino Barbara Auslander James Bailey Rudy Barber Jerry Barlow Clyde Barnhart John Bassett Elwyn Bean Herbert Becker Gerald Bender Sidney Berger Tony Bergin Victor Besosa David Betzner John Bigogno Albert Black Dale Blackburn Richard Bloch Sterling Blumberg Donald Borzych John L. Bosko Carolyn Boswell Lee Brackett Jerome Braun James Brent Brenda Bright Dennis Buege Thomas Burnette William Burns Tony Buszinski Bruce Cairns Ralph Ted Call Frank Carter Joseph Chamides Benjamin Chapman Durjoy Chaudhuri Ramona Christiano Elizabeth Clancy Edward Clark Robert Clark William Clark David Clem Mark Coffey Carl Conway Mike Cook Virgil Cotton Frank Cowperthwaite John Crable Cullen Crews David Culp Gary Dale Marvin Dash Jack Davis John Davis Armine Dedekian Lewis Deets Ernest Derendinger Tom Dexter Daniel Dicken David Donovan Robert Dove Donald Drake Alfred Drexler Merlon Dukes Leon Dumstorff Ralph Dunlap Joseph Dwyer John Dybis Alvin Ehrig Grady Eidson Arnold Eudy Tony Facono Manuel Fernandez Barry Fischer John Foy Fischer Michal Evans Flach Jay Fleckner Kenneth Fordyce Maurice Fortin James Foster Arthur Fraser Joseph Frazier James Frost Joel Fuerstenau Aloys Billy Fuhrmann Daniel Garshman Louis Geijer Robert Gelow Gene Genola Judith Gerke John Giannini Lys Gionfriddo David Gleason Cristina Gomez Jerome Goodyear Lowell Green Charles Gregory Kenley Groce Nikilaus Guy Karla Haber Arline Hall Todd Hall James Fredric Ham Bernard Harahan Lee Hartnek Brian Harvey Albert Hassall Carl Bud Hatley Jeffrey Hayes Roseanna Henchar Greg Hirsch Maria Holban Jack Holmes June Holmes Robert Roy Hornblower Gary Horne Karla Horne Lois Hove Michael Hudac Andy Hudak Jr. Anthony Iacono Angela Iacoretti Donald Janak Dennis Janisse Kazys Jasinskas Eleanor Johnson Leslie Johnson Lloyd Johnson Melinda Jones Vickie Jones Charles Jounakos Mildred Kaplan Martin Keane E. Conrad Keidatz Harry Keith Pat Kelm Harold Kern Helen Kerr Frank Kidrick Moscoe King Willie Klapperick Pat Klemz Robert Kline Charles Kosidowski Jim Kozak Barbara Kramer Ray Kuehn Stanley Kulick Norman Kulig Van Lacey George Lachapelle Nelson Russell Lachapelle Charles Largent Raymond Laubenstein Susan Lawes Jean Sandon Leedy William Leffler Nancy Lemkin Wayne Leslie Paul Lewis Eugene Light George Lindquist Larry Lohr Joseph Lombardo Richard Heath Long Ivan Looker John Lund James Madon Cynthia Malara Carol Malone Benjamin Maniscalco Andrew Manuel Margaret Marani Geoffrey Marshall Larry Marzullo Norman Mass Howard May Terrence McCann John Jack McCarthy John McCormack George McDowell Harry McDowell Jack McElmurry Michael McGuire David McKenzie Tim McNeillie Austin Melton Mike Melton Barbara Meyer Beth Miller Mike Miller Robert Millimaki Gerald Mills Adam Mintz Fred Mirante William Lee Monk Frank Chick Moscato Samuel Moses Marty Mullis Vincent Mulroney George Murdoch George Murphy Terence Murphy Melvin Murray Donald Myers Deborah Mynatt Donald Nord Richard O Heir Floyd Paaso Stephanie Pagano Gene Pagnac Carl Panozzo Teddie Pate Ronald Patrick Sylvester Patrick Lynn Payton Joseph Pecukonis Thomas Pellerin Ronald Pelzel William Pennington Gonzalo Perez Frederick Perise Bill Perri George Pfeil Sandra Phares Ronald Pitney Harry Pleczynski Daniel Pollard Gregory Porchetta William Powell Laura Powers 8

9 James Prag Robert Price Maynard Joseph Prock Robert Pullin Richard Pusty Arthur Reed Julius Mel Reich Alan Reinstein Joe Rendelman Scott Reno Alex Renow Jack Reynolds Robert Rice Raymond Rikkola Frederick Ritzer Linda Lee Ross Jim Roys William Rundle John Russo Gordon Rutland Bill Saffels Dave Salisbury William Saller Belle Saltzman Oliver Sandahl Amanda Nicole Satterfield Clifford Schaack Duane Schmidt Johannes Schols Sigfried Scholz Sandra Schulze Kathleen Semenic Edward Silva Romualdo Silva Ronald Silva Salvatore Silvestro Ron Simkins Harold Skidds Ruth Ann Skinner Bruce Slavinski Richard Smalley Barry Smith Joan Solari Elizabeth Sorenson Engle Southard Leonard Spanier Michael Steckler Richard Steigerwald John Sterling LCDR Finlay James Stewart William Stibitz Chris Stoeckler Lloyd Pat Stoik Allen Sudduth W. Timothy Sullivan Don Surnbrock Richard Swenson William Tausz Charles Fred Taylor Delmar Tesserau Torwald Thomasen Robert Thurber Rodger Tindall Ronald Trainer Joseph Trocki Malcom Tucker Raymond Turckes Juan Vallejo Bert Vandermar Bruce Vento Robert Vickman Otis Vigen Virginia Voegle John van der Vyver Richard Walmach David Watters Joseph Weidner Joyce Weiss Christiane Westlake Glenna Whinery Frank A. White Carl Whitman David Whitney Maurine Willis Donald Wilsterman William Curtis Worrell David Punch Worthington Walter Wozniak Norman Yeamans Philip Yelin Raymond Zellner Warren Zevon John Zipper Walter Zukowski Henry Zurman Caroline Zylka-Parisi Gifts Made In Honor Doug Allison Jerry Barlow Albert Bercher Caroline Bercher Joe Berger Krista Berggren Lisa Bonchonsky Klaus Brauch June Breit Ken Brownfield Wally Bunyea Brian Chamides Mary Jean Connelly John Convertino Mary Cosentino Michael Culmer Jennifer Dawson Cornelis De Jong Ron Diana Mary Donahue James Frost Ralph Gragg Julie Gundlach Robert Guptill Donald Hardy Mary Hessdorffer Karen Jesensky Lloyd Johnson Vickie Jones Harry Krause Craig Kozicki Charles Largent Marilyn Lass Sandy Linden Franz Losch Cynthia Malara Carol Malone John McNamara Joseph Medeiros Marina Mintz Mira Miller Richard O Heir Stephanie Pagano Charles Palmore Ronald Patrick Todd Plummer Daniel Pollard Adrian H. Post Carl Roca Willie Rodgers, Jr. Chris Stoeckler Ruth Thom Robert Thurber Robert Treggett Liz Van Zandt Juan Vallejo Heather Von James Edward Walkow David Whitney Bret Williams Mary Jane Williams 9

10 Donors 2006 $200,000 - $500,000 SimmonsCooper Owens Corning Corp. $100, ,999 Rutland Fire Clay Co. Sigrid Brueggemann $50,000 - $99,999 Roger Worthington, Esq. Estate of Judith Gerke The Richard and Sandra Schulze Family Fund $10,000 - $49,999 Caroselli, Beachler, McTiernan & Conboy, LLC Mary and Robert Cosentino Early, Ludwick, Sweeney & Strauss Rolfe Forland Debbie Fuerstenau and Family Leonette Giannini Goldberg, Persky & White, P.C. Barbara Hoffacker Elaine Holmes Kazan, McClain, Abrams, Lyons & Farrise Waters & Kraus, L.L.P. Eli Lilly & Company Owens-Illinois, Inc. Merck & Co., Inc. Scott Monk Jean and James Rion Donna Saller Kirsten Silva Peggy Sterling The Nathan Cummings Foundation Fujirebio Diagnostics, Inc. Linda and Robert Treggett Irene Turckes Maria Vallejo Nicholas Vogelzang, Esq. Jim Whinery 5K Walk for Hope $5,000 - $9,999 Marcia Abbott Doug Allison Sara Biddle Bilbrey & Hylla, P.C. Bonnie Burke Mary and Sean Donohue Doris Dukes Sarah Kaplan Mazur & Kittel, PLLC Carol Melton Cheryl Mueller Law Offices of Peter T. Nicholl The Pleczynski Foundation Marilyn Porchetta Schroeter Goldmark & Bender PS Janet Simkins 10 Nancy Tegeder & Ronald Astbury Hannelore Tucker $1,000 - $4,999 Rebecca Albarado Michael and Sabrina Armitage Artists4Hope Judith and Joe Berger Bevan & Associates, LPA Joan Blumberg Richard and Elizabeth Burton Carmir Properties, LLC Law Office of Victor M. Carrera, P.C. Joan Crable Daymarc Foundation Mary Dearing Angie Deets Debra Dicken Catherine Donovan Patricia Dybis First Brunswick Mortgage Gail Geijer Grace Goodnite Goshen General Hospital Harvit & Schwartz, LC Carol Hayes Heat & Frost Insulators & Asbestos Workers, #17 Lorna Hooper Judith Hudak Cindy Jesso Larry Lohr John Giannini Mae Johnson Sharon Johnson Dorothy Jordan Daniel Klein Judy Kosidowski Shelly Kozicki Linda Kunz Rosie Lacey Lansing Division Michigan Chapter N.E.C.A. Franz and Maria Losch Joseph Losch Latanyta Manuel John McNamara Fight for Lives Marlene Mirante Sue Monk and Family Karen Morris Norine Mullins Carla Myerson and Robert James Jacquelyn Paaso Stephanie Pagano Rosemary and Ronald Patrick Olive Pellerin & Family Helen Pitney Vera Reynolds The Grover Hermann Foundation Evelyn and Carl Roca Dana Rutland Estate of Bill Saffels David Sorenson Time Warner Employee Grant Programs University of Missouri-Columbia Faith Vandermar Marjorie Whinery Lynn Williams Mary Jane and Loring Williams $500 - $999 Ann Abbe Ammie Archer Baron & Budd, P.C. Pam Becker Theresa Bosko Branch Banking & Trust Company Janice and Ray Bright Cars 4 Causes Central Jersey Street Hockey Assoc. Lori Coghlan Beth and Harold Commander Bibis and Dave Consalvi Andrea Conway Loretta and Robert Cooney Denise and Robert Dangremond Marcia Dedekian James Delahanty Doran & Murphy, LLP Kimberly Duchossois Alice Dumstorff & Family Shirley Eidson Kendra Ferreira Patricia and Charles Finkenbine The Family of Aloys Billy Fuhrmann Charlene and David Geffen Joseph Gionfriddo Lisa and Robert Glosson Goldenberg, Miller, Heller & Antognoli, P.C. Linda and Donald Gray Christopher Hahn Laura Harbut Higgins Family Foundation Constance Hoogerland James Hopkinson Terry Huchton Chris Hudac Mark Hudac Friends and Co-Workers of Jeff Hayes Pasquinelli Homes, LLC Robert Jones Evelyndale Kern John Koch M.T. Konet Roberta Kuehn Estate of Nelson Russell Lachapelle Verda Mae Lewis Julie Lickteig Richard Long M Booth & Associates, Inc. Raymond Madden Madden Funds Management, LTD Alexandra Mammes Marjorie McCoy

11 Kathy McCray Walker Linda McDowell Lori Mealer Merck Partnership for Giving Jan and Steve Miller Steven Miller Joan Millimaki Donna Papa Christine Pate and Family Plumbers & Steamfitters Local No. 11 Daniel Praino Prudential Foundation Matching Gifts Amy and James Reardon Melissa Risk Pamela Rodgers Joseph Roti Roti Kimberly Schmidt Henry Shatkin Sieben Polk LaVerdiere & Dusich Total Petrochemicals USA, Inc. Thelma Van der Vyver Anne, James and Taylor Van Dyke Susan Vento Patricia Vickman Josephine and John Wendler $100 - $499 Anne Aaberg Abbott Laboratories Abbott Laboratories Employee Giving Debra and David Acker Lodema Adams Ahrens Greenhouse, Inc. AIG Matching Grants Program Allegheny North Veterinary Hospital Bonnie and Bryan Allem David, Rachel and Caitlin Allgaier AllianceBernstein Allodi Family Foundation Thomas Almond Amaranth Group Inc. Denise Ambre American Express Gift Matching Program Bonnie and John Anderson Carole and Charles Anderson Diane Anderson Joan and David Anderson Rose Anderson Andia Telecom Jan and Wayne Andresen Claire Andrews Barbara Apking Sam Armato Kathleen and Andrew Aromando Asbestos Workers Local No. 2 Dolores Asturino Linda and Rod Ausmus Paul Auten Barbara and Todd Bachman Ruth and Dale Bachman Susan Bailey Audrey and Frank Baker Jackie and Bruce Ball Roberta Bannister Mariana Barajas Julie and Richard Barber Bargain Network, Inc. Annette Barlow Mary and Jose Bartolo Clarice and John Batt Bay Area Association of SMACNA Chapters, Inc. Beach Mortgage of NC, Inc. Yancey Beamer Virginia Bean Mary Beaubien Susan and Mark Becker Terry Becker Valerie and Ronald Bedoe Cheryl and Thomas Behan Susyn Berger and Barry Jacobs Peggy Bergin Mary Bergmann Myra and Art Berman Nancy and Allan Bernard Hedy Bextine Carol, Gary, Jennifer and Emil Beyer Mary Bjork Raye Black Christopher Blanc Susan and Paul Blease John Bledsoe Maryann Bloch Bob King Buick-Pontiac-GMC, Inc. Janette and Clay Bollinger Maureen and Donald Bonistalli Boomer s Robert Borzych Heather and Matthew Bosko Justin Bosl Dean Boswell Deborah Bott Dan Botti William Boyer Virginia Brackett Heidi and Jeff Bradley Marcia Bradley and William Hembel Connie and Ron Brasel Brayton Purcell Betty Breit Faculty and Staff Barbara Brennan School of Healing Leslie and Marvin Brittman Courtney Broaddus UCSF Bernadette and Tim Broccolo Nora and John Brown Patricia and Ronnie Brown Brown University Medical School Catherine Buege Jennifer Buell Shawn and Christine Bullock Anne Burbine Judith Burcar Elizabeth and John Burgee Doris and David Burns Jess & Harumi Burns Rosemary and John Bury Nancy Buszinski William Buszinski Patti Butler James Byrnes Marilyn and Thomas Cahill Craig and Laurie Canedy Susan Canon Capitol Insurance Group Virginia Cappelli Madge Carlson Jeff Carpenter Stephen Castellarin Lynn and Chad Castro Jerry, Chris and Jeana Ceglia Margaret and Pat Ceglia Joyce Cerbasi Joseph Cerne Rosemarie Cerundolo Subhas Chakrabarty Grace Chamides Champion Resort Maintenance Charles Lambert Frank Childers Betty Chlysta and Family Julie Christ Carol and Joseph Clark Cheryl Clark Grace Clark Mary Joan Class Judy Clem Margo and Mike Clements CMC Claims Management Services, LLC James Coble Ann and Michael Coffey Peter Cohen Rose Coletti Collector s Corner Jaime Collins Julie and Kevin Collins Brian Connelly Connelly Electric Co. Sabrina and James Connolly Carol Consalvi Mae Consalvi Mary and Richard Consalvi Amy and Tom Cook Lexine and Steven Cook Matthew Cooper Debbie and Tom Corcoran Nancy Corser Joe Cosentino Family Marcia and Bernie Coski James and Catherine Costello Kathleen Costello Cheryl Cotton Jonathan Couch Roberta and Arnold Coven Jennifer Cribb Kim and Tom Croisant 11

12 Donors 2006 John Cryer lll Teresa and Brian Cullen Beverly Culp Daniel Culver Jeanne and Gary Cunningham Mary and Joseph Cushing August Cwik Keith Czepiel Janice and Michael DaPrato Fran Dash and Family Barbara Davis Deborah and Patrick Davis Laura and Brian Davis Paul Davis Anna and Anthony De Felice Jean and Joseph Deasy The DeHuff Family Johnnie Deloach Ken Dennett Tearesa Derendinger Brian Derrer Kimberly desoto Bonnie Diana Karen and David Dille Barbara and Thomas Dillon Mary and Daniel Dillon Dominion Foundation Matching Gift Program Mae Doubek Robert Doubek Mary Dougherty Anne Doyle Charlene Drake Gregory Dray Marian and Paul Drolsom Natalie and Patrick Dumstorff Maureen and Terrence Dunne Daniel Durkin Joseph Dwyer Mary Dwyer Thomas Dwyer Jack Dybis Marguerite Dyer E. J. Mullins Company Deborah and Scott Early Betty Echerd Edwards Family Beth Eggert Irene Eichel Terry and Gary Einig Lori Enloe N.B Epstein Bridget and David Erfort Celeste Eshenwald Anne Etter Koren Evans Louise and Frank Fargo Susanna Ferebee The Finkelsteins Jaclyn Fischer Bridget and Michael Flaherty Trish Flaherty Linda and Christopher Ford 12 Martin Foreman Priscilla Fortin James Fox Arthur Frank, MD, PhD Janet Fraser Joan Frazier Fred J. Bastie & Associates Nadia and Ray Freed Donna Frey Nancy and Gregory Fritz Jacqueline and David Froberg William Frost Roy E. Frost and Roy A. Frost Andrew Gagliardo Pamela Garnick Gatlin Plumbing & Heating, Inc. Karen and Frank Gaudio Gail Geijer Louis Geijer Ruthe Gelow Karen and John Giacopelli Cynthia and Richard Giannini Kelli and Shane Gilbert Maleah and Trent Gilles Mary and Joseph Gillis & Family Amy Glass Janet Gleason Jill Golde Shelli Golden Betty and Stanley Golebiewski David Golebiewski Lisa & Christopher Golebiewski Michael Golebiewski Michelle & Todd Golebiewski Tracy & Mark Golebiewski Lorie and Steven Golich Teresa Gomez Sally Goodyear Marguerite and Thomas Gordy Jeanne Gorman Jill Gould GPL Investments Lisa Grabowski Carol Grasha The Gravestar Foundation Richard Green Shawn Green Angela Greenberg Adriane and Benjamin Greenberg Barbara and Larry Greenfield Ted Griffin Albert and Lucy Guerra Tracey Guthrie Anne and Thomas Hagood Beverly Haig William Hall and Carla Hatley YE Hall, Jr. Erica and John Hamill Jeannie and Thomas Hamilton Mary Hamilton and Irvin White Harry Handlin Jill and Bernard Hanley Molly and Kevin Hanley Suzanne Hanley Virginia and Marvin Hansen Nancy and David Hanson Paulette and Robert Harnach Timothy Harrigan Barbara Harris Gerald and M.J. Harris Mary and Brian Hart Stephanie and Robert Hart Kay and Michael Hartmann Patricia Hatley Mary and Mark Havard Monica and Roger Haverkamp Gary Hayden Health Care Suppliers, Inc. Heat & Frost Insulators Asbestos Workers Local #49 Alan Heine Kathy and James Helget Sharon and Keith Helsby Paul Henderson Gloria Henn Janette and Mark High Mary Ann and Ron Hill John Hiller Norma and William Hindman David Hines Ann Hirsch Jeanne Hirth and Tom Kluesenor Hi-Tech Lisa and Paul Hjulberg Maureen and Gene Hochberg Daniel Hodgman Margot Hodgson Frederic Hogan Leslie Holloway and Al Surink Marcia and Kevin Horan Patricia Hornblower Colleen and John Horrigan Karen and William Hosticka Catherine and Neal Houcek Walter Houghtaling Houston Wire & Cable Company Agnes Hudac Darlene and Gerald Hudac Janis and Lad Hudac Nancy and David Hudac Peg and Pete Hudac JoAnne and Jim Huff Susan Humphres Elaine and C. William Hunt Margaret Hunt Hunt Management Incorporated IBM Robert Ingraham International Association of Heat & Frost Insulators and Asbestos Workers International Brotherhood of Electrical Workers Kim Izzarelli and Gary Tannenbaum Renette Janak

13 Linda Janisse Aldona Jasinskas Jefferson Staff Arnold Joffe Maureen and William Johnson Diane Jones Sophia Jounakos Barbara Kaiser Sarah and Gary Kaplan Jill Kaplan and Mackenzie Trenk Joan and Stephen Karsay Betty Kase Carol Kase Richard Kassin Jennifer and Edward Kaufman Dawn Keagy Lainy and Marty Keller Michael Kelly Kelty Lawn Care, Inc. Pamela and Mark Kendall Tom Kestranek Elaine and James Kingham Lynda Kirby Suzanne Kisbye Ladonna Klapperick Laura Klee Carol and Marty Klein Eric Klein Rebecca Kline Deborah Knecht Robert Kohn Sarah and Tom Kolar Iris and Ron Kovarsky Joel Kowalski Paula and Dennis Krauss Lori and Brad Krei Dennis Kroll Bill Kruchko Tami and Todd Krzyskowski Peter Kucharski Becky LaBlanc-Willis Lacava Cynthia Lancaster Diane Landosky Eleanor and Anthony Lascola & Family Ina Lavin Bonnie LeBrun Phyllis and Larry Lee John Lehr R.M. Lemoine Jennifer Lewicki Lewis Architectural Services, PC Catherine Light-Holmes John Linden Ellen and Brian Liston Charlene and George Locasto Loffredo Brooks Architects, PC Janet Lombardi Loyola University Employee s Federal Credit Union Frances Lund Barbara and Leonard Lundy Joan Luning Shannon and Douglas Luzecky Lynch Dental Center Partnership Karen and Steve Lyons Sarah Lytwyn Kathleen and Kenneth Maciolek Mary Ann and Ken Macvey Dorothy Madden James Maddock Niamh and Philip Maddock Jeanne Madon Carol and J.L. Maginn Majestic Pools & Landscape Catherine Malara Patricia and James Maley Malibu Textiles, Inc. Richard Malley Steve Maltz Marisa Maniscalco Sam Marchese Laura and Brad Marion Mark J. Walsh & Co. Sharon Marks Heather and Nicholas Marshall Julia Marshall Beth and Jeff Maserang MassMutual John Mathias Piccerelli, Gilstein & Company Nathalie Mattson Mary and John Mavero Terrie and James McAmis Karen and Stephen McCarthy James McCartney Ruthann and Thomas McCarty Anne McConnell Jerry McCorkle Mary McCormack McCue & Husband Law Firm January and Brett McCulloch Jack McElmurry The McGowans Rita McGuire Anne and Michael McKeon J.H. McKerring Jane and Joseph Medeiros Christine and Peter Melchert Glenna and Jerry Metzler Marla Meyer Robin Meyerhoff Microsoft Matching Gifts Program Mike Middleton Diane Miletto Lucy and Tony Miller Lisa Miller and Robert Schumacher Joann Mirante Kathleen Mirante Sharon Mirante Teresa Mirante Geralyn Mirante Marley Robert Misen Family Larry Moore Rosemary and Renzo Mori Catherine and Frank Moroni Frances Moscato Donna and Morton Moss Wanda and Roger Mozingo Robert Mullin Lynn Mullis Jean Mulroney & Family Kathleen Murphy Mark Murphy Shawn Murphy Hitchcock Denise Murray Jacqueline and Thomas Murray Jean and Robert Murray Joe Murray Patricia Murray Smithmoore Myers Kenneth Nash Roseanne and Gordon Nash Betsy and Bob Nelson New Life Baptist Church NewYorkFire.com Shop, Inc. Bruce and Amy Noble Jacqueline and Walter Norton Chari and Robert Nyberg Mary and Erwin Oberg Therese and William O Brien Mary and John O connor Hugh O Connor Friends of Manuel Fernandez Sandra O Heir Tracy O Heir Jan and Len O kray Donald and Lynne Olson Linda and Francis Olson Bradley and Sandra O Neill Margaret and Daniel Otton Chris Pagano Jacqueline and Joseph Pagano Lynne and Paul Pagano Meaghan Pagano Rockin for a Cure S. J. Pagano Sal Pagano Waterworks, Inc. Pamela Paine Genevieve Palczynski Cheryl Park Sharon and Tom Partch Pate Construction Co., Inc. Ann Patrick Thomas Patrick Veronica and Theodore Patrick Morgan Pecukonis Kathleen Pennington Valli Perera Gonzalo Perez Susan and Carlos Perez Robert Pernini Gina Perri and John Ferden Pfizer Foundation Matching Gifts Program JoAnn and Gene Pierce James Pietro and Frank Odorisio Pinehurst Insurance Maureen and Faustin Pipal 13

14 Donors 2006 Andrew Pitler Paula and Jon Plummer Meg and Bill Pokorny Helen and Frank Polichene Rose and Patrick Pollard & Family Barry Popkin Port Orchard Yacht Club Vicki Price Suzanne Prince Tom Pusty Quality Construction Nancy Quinn Robert Rahe Sally Ramsey Frances and Steven Rasmussen Jane Reddecliff Redmond Family Mary Reebe Anne and Dennis Reed Regina and Gerald Reich Laraine and Richard Reid Linda Reinstein James Renfroe Joan Renow Donna and Alan Resetar Diane and Martin Reynolds and Family Ty Rice Emmy and Robert Rigali Theresa and John Rigas Kathy Rink Michael Ritzer RJ Simon, LLC Sandy Robeson James Robinson Anne and Francis Roche Barbara Rodolitz Arlene and Evans Ronshausen Marie and David Rorick Family Wilma Rosen Linda Rosenblum Dennis Rosenfeld Andrew Rosenzweig Henry Ross John Ross Stephen Rostan Barbara Cis Rundle Rose Russo R. Jack and Joanne Ruthbard Anne and Thomas Saal Brian Saal Carol and Bert Sacco Elizabeth Saddler Lysa and Phil Saran Bud Sargent James Sassano Joseph Sayre Adeline Schaack Claire Schafer Kris Schindler Jackie Schirn and Robert Drzymala Mary Rea Schiszler Charlotte Schmidt 14 Brandi and Marshall Schoewe Lt. Gen Daniel Schroeder (RET) Schroeter Goldmark & Bender PS Kathy Schultz Linda Schulze Lynn and Daniel Schuman Colleen Schwartz Wendy Selene Stu Seltz Dennis Semenic Greta Senn Elizabeth and Michael Shanahan Maryann and Richard Shanas Betty Siegel and John Merck Estate of Romualdo Silva Rose Silva Doris Silvestro Beverly Sistare David Skelding Annette and William Skelton Mary Ann and Robert Skowronski Ann Marie Slagle Deborah Slavinski Shannon and Brian Smith Vickie Solis Zachary Solomon Susan, Anthony and Christina Sorboro South Brunswick Islands Woman s Club Sheila and Bob Spector Siobhan Spillane Christine Stanish Alice Steigerwald Phyllis Stibitz Janna and James Stidham Marjorie and Edward Stinson Lloyd Stoik Mark Stokes Kate Stoune Russell Stuart and Mark Sherman Christine Stuhlmiller Superior Electric of Lansing Inc. Nancy and Daniel Swanson Shirley Swenson Judith and Richard Swiderski Molly Ann Swock Mary Tackett Scott Tappan Bernard Taschini & Family Mary Beth Tate Lorraine Tausz Estate of Charles Fred Taylor Pat and Rick Terbrock The Hartford Steam Boiler Inspection and Insurance Martha Thomas Evelyn Thomasen Lisa and Mark Thomasen Amy Thompson Edna and Jeff Thompson Robert Thomson Robert Tiberi Philip Timyan Ton Hall Building Corp., Inc. Gwen and Pietro Tonino The Officers and Employees of TPA Design Group Patricia Trocki and David Tennessen Paula and James Ulma United Transport Services, Inc Bret Van Dyke Judith and Michael Van Handel Ramakrishna Velamati Vic West Plumbing LLC Ruthann and Charles Vihon Sheila and Paul Villamil Stephanie and Randy Vlach James Vogel and Erin McCarthy Suzanne Von Drehle Mary Ellen Wagner Patricia and John Waldorf Jerry Waldrip and Marice Frazer Janet Wall Fred Walls Donald Ward Co-workers Washington University School of Medicine Todd Wasserman Arlene and James Watts James Watts Susan and Richard Weiner Betty Weiss Carolyn Weiss Donald Wenker West Bay Psychiatric Associates Colleen and Terrence White Martin White Mary and John White Elaine Whitman Joy Whitney Harriet and Paul Wiedner Anne and Joseph Wild Becky Willard Cheryl Williams Shane Williams Wilson Downing Group, LLC Mary Witherow Irene and Jim Witmer Linda Wittig and John Shoemaker Marc and Solveig Wolstenholme Mildred Woods Wooten s Electric, Inc. Regina Wozniak & Family Richard Wray Wylaco Supply Company Evan Yegelwel Dana Zeip Helen Zielinski and Marie Hagman Jocelyn Zuelch Marguerite Zukowski

15 Meso Symposium Sponsors The Foundation is extremely grateful to the sponsors who helped make the 2006 International Symposium on Malignant Mesothelioma possible. SimmonsCooper, LLC Roger Worthington, P. C. Eli Lilly & Co. Waters & Kraus, LLP Kazan, McClain, Abrams, Lyons, Farrise & Greenwood Merck & Co., Inc. Fujirebio Diagnostics, Inc. Foundation Directors, Science Advisors & Staff Board of Directors Science Advisory Board Foundation Staff Nicholas J. Vogelzang, M.D., Chairman Director, Nevada Cancer Institute M. Ann Abbe, Secretary Associate Vice President for Development, University of North Texas Ulf Jungnelius, M.D., Treasurer VP, Oncology Clinical Research Takeda Global Research and Development Mary Cosentino, Esq. Adjunct Professor of Law, Loyola University Chicago School of Law Michael Harbut, M.D., M.P.H. Chief, Center for Occupational and Environmental Medicine Latanyta Manuel Canton, MI Harvey Pass, MD Professor of Surgery and Chief of Thoracic Surgery and Thoracic Oncology, NYU School of Medicine Susan Vento Education Minnesota Field Staff Harvey Pass, M.D., Chairman NYU School of Medicine Steven Albelda, M.D. University of Pennsylvania Steve Hahn, M.D. University of Pennsylvania Raffit Hassan, MD National Cancer Institute Hedy Lee Kindler, M.D. University of Chicago Dan Miller, M.D. Emory University Lary A. Robinson, M.D. H. Lee Moffit Cancer Center Victor Roggli, M.D. Duke University W. Roy Smythe, M.D. Texas A&M Robert N. Taub, M.D. Columbia University Joseph R. Testa, Ph.D. Fox Chase Cancer Center Eric Vallieres, M.D. Swedish Cancer Institute Claire Verschraegen, M.D. University of New Mexico Christopher Hahn Executive Director Rob Grayson Director of Development Jill Wayne Community Liaison & Patient Advocacy Director Maja Belamaric Development Associate Trish Cerin Administrative Assistant 15

16 Mesothelioma Applied Research Foundation research - education - support - advocacy NONPROFIT US POSTAGE PAID SANTA BARBARA, CA PERMIT NO Publication of the 2006 Annual Report sponsored by Fujirebio Diagnostics, Inc. - makers of MESOMARK.

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