Spectral CT in rabbit VX2 liver tumor models: adaptive statistical iterative reconstruction associated with monochromatic image

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1 Spectral CT in rabbit VX2 liver tumor models: adaptive statistical iterative reconstruction associated with monochromatic image Poster No.: C-1512 Congress: ECR 2015 Type: Scientific Exhibit Authors: M. Wang, J. GAO; Zhengzhou/CN Keywords: Abdomen, CT, Angioplasty, Biological effects DOI: /ecr2015/C-1512 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. Page 1 of 7

2 Aims and objectives To evaluate the value of adaptive statistical iterative reconstruction (ASIR) associated with monochromatic image of spectral CT in the rabbit VX2 liver tumor models. Methods and materials The protocol was approved by the Committee on the Ethics of Animal Experiments of Zhengzhou University. This study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health On the 7 th #8 th day after implantation,24 successfully implanted rabbits were imaged with spectral and conventional enhanced CT with a random acquisition order and a 24h interval. The scanner was the Discoverey CT750HD and the workstation was the 4.6 GE Healthcare Spectral CT images with filtered back projection (S-FBP) and adaptive statistical iterative reconstruction (S-ASIR)(40%ASIR),as well as conventional CT images with FBP (C-FBP) and ASIR (C-ASIR)(40%ASIR), were generated,respectively. The region of interest were choosen at the obviously enhancement of the tumor and the normalliver tissue The tumor-to-liver contrast-to-noise ratio (CNR) and image noise of the four groups were calculated. (The CNR were calculated at the optimal CNR kev in the spectral CT groups).the lesion conspicuity scores(lcs) and overall image quality scores(oqs) in the four groups were recorded. Results The CNR of the group (S-ASIR)(3.10±1.70) was significantly higher than that of the other three groups.(p#0.05),and There was no significant differences between group(c-asir)from group(s-fbp)(2.63±1.59vs2.50±1.60,p=0.491).the image noise Page 2 of 7

3 of group(s-asir) had no significantly difference from that of group(c-asir) (7.43±1.27vs6.88±21.23,p=0.118),but lower than that of group(s-fbp) (9.05±2.37)and group(c-fbp)(9.87±1.05),(p#0.05).lcs of group(s-asir) had no significantly differences from that of the group(s-fbp) (4.01±0.54vs3.85±0.52,p=0.119),higher than that of group(c-asir) (3.31±0.48) and group(c-fbp)(3.29±0.46).the group(s- ASIR) had the highest OQS (4.00±0.57vs 3.58±0.43(C-ASIR)#3.19±0.29(S- FBP)#3.37±0.47(C-FBP)#p#0.05) Images for this section: Fig. 1: S-ASIR image Page 3 of 7

4 Fig. 2: S-FBP image Page 4 of 7

5 Fig. 3: C-ASIR image Page 5 of 7

6 Fig. 4: C-FBP image Page 6 of 7

7 Conclusion Spectral CT associated with ASIR which combine have the advantage of increasing the image CNR and reducing the image noise, improve the lesion detection and image quality, without increasing the radiation dosage. Personal information References 1. Machida H 1, Fukui R, Tanaka I,et al. A method for selecting a protocol for routine body CT scan using Gemstone SpectralImaging with or without adaptive statistical iterative reconstruction: phantom experiments.[j].tanaka I Jpn J Radiol Apr;32(4): Lv P,Lin XZ,Chen K,et al.spectral CT in patients with small HCC:investigation of image quality and dianosic accuracy[j].eur Radiol,2012,22(10): Guimaraes LS,Fletcher JS,Harmsen WS,et al.appropriate patient selection at abdominal dual-energy CT using 80kV:relationship between patient size,image noise,and image quality[j].radiology,2010,257(3): Cui Y, Gao SY, Wang ZL,et.al.Which should be the routine crosssectional reconstruction mode in spectral CT imaging: monochromatic or polychromatic? [J]. Br J Radiol Oct;85(1018):e Page 7 of 7

CT findings in Differential Diagnosis between Tuberculous Pleurisy and Malignant Effusion

CT findings in Differential Diagnosis between Tuberculous Pleurisy and Malignant Effusion Poster No.: E-0084 Congress: ESTI 2012 Type: Scientific Exhibit Authors: S. S. Shim, Y. Kim; Seoul/KR Keywords: