Graduate School of Frontier Sciences The University of Tokyo

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1 Graduate School of Frontier Sciences The University of Tokyo The Transdisciplinary Approach & Intellectual Adventure

2 The Transdisciplinary Approach: A Creative Force The Graduate School of Frontier Sciences (GSFS) is a school for Master and Doctoral students that was established through comprehensive cooperation of all existing departments of the University of Tokyo. It is made up of the Division of Transdisciplinary Sciences, the Division of Biosciences, the Division of Environmental Studies, and the Department of Computational Biology. All of them share the mission of solving the challenging problems facing humankind through the pursuit of education and research on the frontiers derived from established Milestones Apr 1998 Graduate School of Frontier Sciences founded. Apr 1999 Student enrollment begins. Mar 2001 Bioscience Building constructed. Mar 2002 Phase 1 of Transdisciplinary Sciences Building construction ends. Apr 2003 Department of Computational Biology established. Sep 2003 Second construction phase for Transdisciplinary Sciences Building concludes. Dec 2003 Transdisciplinary Sciences Laboratory constructed. Apr 2004 Department of Medical Genome Sciences launched. Oct 2004 Kashiwa Research Complex constructed. Apr 2005 Research Center for Total Life Health and Sports Sciences established. Mar 2006 Construction of Environmental Studies Building finishes. Apr 2008 Department of Ocean Technology, Policy, and Environment established. Center for Omics and Bioinformatics established. Department of Frontier Informatics moved to Graduate School of Engineering. Apr 2009 Bioimaging Center established. Apr 2011 Functional Proteomics Center established. Dec 2011 TJCC (Todai-JAXA Center for Composites) established. Apr 2015 Department of Computational Biology and Medical Sciences established. Tripolar Structure The Hongo Campus focuses on traditional studies in specialized fields and on intrinsic development of those areas, while the mission of the Komaba Campus is to pursue interdisciplinary education and research. In contrast, the goal of the Kashiwa Campus is to pursue intellectual adventure by going back to the basics of existing disciplines and interlacing them into a transdisciplinary synthesis of education and research. The addition of Kashiwa Campus to the alliance formed by its sister campuses completes the University of Tokyo s vision for a tripolar structure. disciplines. This undertaking is courageously carried out using transdisciplinary approaches in which the school s departments are organized to cover a broad cross-section of research topics, under the leadership of diversely experienced faculty members from not only the University of Tokyo, but also other research and educational institutions around the world. About 7,000 students have completed the school's program, and about 1,300 students are currently enrolled in its departments. Graduate School of Frontier Sciences Operating as a new stronghold for pioneering education and research, the Kashiwa Campus pursues intellectual adventure and the creation of new academic fields through graduate-level education and researchgrounded on a fusion of disciplines at different states of maturity. Kashiwa Creation of new academic fields Division of Transdisciplinary Sciences Division of Biosciences Division of Environmental Studies Department of Advanced Materials Science Department of Advanced Energy Department of Complexity Science and Engineering Department of Integrated Biosciences Department of Computational Biology and Medical Sciences Department of Natural Environmental Studies Department of Ocean Technology, Policy, and Environment Department of Environment Systems Department of Human and Engineered Environmental Studies Department of Socio-Cultural Environmental Studies Department of International Studies Graduate Program in Sustainability Science - Global Leadership Initiative Research Center for Total Life Health and Sports Sciences Serving society through regional collaboration, university-industry partnerships, and international exchange Working together with the cities of Kashiwa and Nagareyama, Chiba Prefecture, Chiba University, and local businesses, the Graduate School of Frontier Sciences actively engages in regional collaboration, university-industry partnerships, and international exchange in order to put its research achievements to work for society. As part of this mission, several major programs have been launched to use GSFS technologies to develop the Kashiwa area into a smart city that is friendly to seniors and the environment, starting with the founding of the Urban Design Center Kashiwa-no-ha (UCDK) in 2006, and followed in 2008 by the opening of the University of Tokyo Future Center (UTFC) and the formulation of Kashiwanoha International Campus Town Initiative. This effort is further supported by the designation of Kashiwa City as an ITS Field Operational Test Model City in 2009, and as a FutureCity and a Comprehensive Special Zone for Regional Revitalization in Also, pilot studies are being conducted to identify technologies necessary for smart cities, and these technologies will be translated into new export industries. As a hub for regional collaboration, the UCDK hosts seminars for local residents, student-led events, and other such activities at its facility, which is located near Kashiwa-no-ha Campus Station. The UTFC, which serves as a center for pilot studies, opened an office near that station in 2012, and constructed a 6,000-square-meter research building in the 2013 academic year. GSFS projects in partnership with industry include the incubation of UT-launched venture firms, which are run mainly at the Tokatsu Techno Plaza (Chiba Prefecture) and the Todai Kashiwa Venture Plaza (SME Support, Japan). As part of efforts to foster international exchange, the International Center, Kashiwa Office provides international students and researchers with support services for visa procedures and life in Japan. In addition, Kashiwa II Campus has dormitories for international students and researchers that are designed to be an international village where people from around the world live and learn together. Urban Design Center Kashiwa-no-ha (UCDK) University of Tokyo Future Center (UTFC) In addition to functioning as the university s base for the first half of undergraduate studies, the Komaba Campus engages in interdisciplinary education and research at the second half of undergraduate and postgraduate levels in the specified areas based on interaction with other disciplines and the world outside the campus. Komaba interdisciplinary academic fields Hongo Traditional academic fields Facilities Center for Omics and Bioinformatics Bioimaging Center Functional Proteomics Center Serving as the linchpin of the tripolar formation, the Hongo Campus undertakes education and research in traditional disciplines at the second half of undergraduate and postgraduate levels. TJCC (Todai-JAXA Center for Composites) * JAXA: Japan Aerospace Exploration Agency Tokatsu Techno Plaza 2 3

3 Division of Transdisciplinary Sciences Comprising the three departments of Advanced Materials Science, Advanced Energy, and Complexity Science and Engineering, this division creates new fields that will serve as the foundation for future sciences, and produces the individuals who will advance those sciences. Department of Advanced Materials Science We nurture material scientists to be ready to go out into the world! Department of Complexity Science and Engineering Striving to innovate multiscale complexity sciences and technologies The Department of Advanced Materials Science was established as a center for education and research in materials science, with the founding faculty drawn from the University of Tokyo s Faculty of Engineering, Faculty of Science, and Institute for Solid State Physics. By strengthening our partnerships with RIKEN and other external research organizations, we seek to unlock the hidden potential of materials through STM image of 2D water cluster formed on Pt surface research led by professors who have attracted global attention for their work in new materials development, process technologies, and nanotechnologybased advanced metrology, including such areas as soft matter, quasicrystals, semiconductors, plasma materials processing, single molecule reaction control/ measurement, ultrashort-pulsed laser spectroscopy, multi-ferroics, synchrotron X-ray radiation measurement, and advanced measuring techniques based on nanotechnology. At the same time, we strive to create foundational technologies for the 21st century through mechanism elucidation and theory construction for various phenomena, invention of new devices, and establishment of innovative materials measurement techniques. We provide students with ample opportunities to take lecture classes and seminars in materials science, all the way from the fundamentals to the advanced level, under the tutelage of our distinguished faculty, which includes international members. In doing so, we put students in direct contact with the frontiers of materials science across the spectrum from basic science to applications in engineering. This comprehensive educational and research environment is guaranteed to reward students with a satisfying graduate study experience, so come join us and set sail for the fascinating world that awaits you. Boron-based Multi-shelled structure of boron- and aluminum-based icosahedral cluster solids Aluminumbased Diffracted x-ray tracking (DXT) of single functional protein molecule le to the universe. The Department of Complexity Science and Engineering was established with the aim of investigating various problems related to complexity through an unprecedented approach that integrates science and engineering, and training scientists and engineers who can create new paradigms of complexity science and engineering. We are now confronted with realities in which a variety of complex nonlinear phenomena, which are irreducible into simple rules, exist in both natural and artificial systems. Furthermore, through the emergence of new nonlinear concepts such as chaos and fractals, it is becoming obvious that dynamically and computationally complex systems, in which various nonlinear elements strongly interact with each other, are ubiquitous in this real world, and it is widely expected that understanding such complex systems can create new areas of science and technology for the 21st century. We strive to innovate new complexity sciences and technologies by taking a transdisciplinary approach to multiscale complexities ranging from the nano to cosmic levels, mainly through our three modules of Brain-Bio, Astrobiology, and Extreme Matter. We also work to construct a Complexity platform founded on the theories and techniques common to these three modules, including those pertaining to mathematics, information, visualization, and machine learning, with the aim of advancing research and human resource development for opening up new frontiers. Mars may have had a warm and wet climate Data analysis by using machine learning methods Astrobiology Module Complexity Platform Brain Module Analysis on brain and sensory systems Extreme Matter Module TST-2 high-temperature plasma confinement device Molecular image of graphene surface Department of Advanced Energy We boldly strive to pioneer advanced energy and realize its efficient use Nuclear Fusion Research Education Program We create new frontiers at the forefront of nuclear fusion research The Department of Advanced Energy transcends the boundaries of contemporary energy engineering to pursue pioneering research on emerging fields of energy engineering for the future. Our comprehensive program of education and research explores energy with a transdisciplinary approach that spans space energy systems engineering, advanced structural / material engineering, applied superconductivity engineering, electromagnetic energy systems engineering, control engineering, plasma science and engineering, nuclear fusion engineering, and other energy-related fields. Specifically, our activities include basic research on such areas as generation / conversion / control of energy under extremely high-temperature (e.g., plasma)or high-enthalpy conditions, extreme structural / material engineering, efficient utilization / storage / transport of energy, superconductivity-based utilization of high magnetic fields, solar/space plasma physics, and nonlinear science; and applied research on such fields as R&D on plasma fusion energy and future space transport vehicles, resource and environment-conscious energy systems, space environment exploitation, smart structures/materials, torus plasma formation / merging, superconducting magnetic levitation, smart grids, electric vehicles, and wireless power supply systems. In order to develop individuals capable of taking up the many radical challenges related to energy, we constantly pursue advanced research projects and cultivate an international, transdisciplinary research environment. Nuclear fusion is the ultimate energy source for humankind, offering environmentally friendly energy derived from abundant resources. Japan is producing remarkable results in nuclear fusion research, and is playing a leading role in advancing ITER, an international project aimed at realizing nuclear burning plasma. The Nuclear Fusion Research Education Program was established at the GSFS in 2008 by the Department of Advanced Energy and the Department of Complexity Science and Engineering in order to nurture a steady stream of talented human resources to serve as global leaders in future nuclear fusion research. This program is steadily building up a strong track record in nuclear fusion-related education and research through its two core curricula the Transdisciplinary Education Curriculum, which provides comprehensive, systematic education in a broad array of basic sciences, and the Practical Research Education Curriculum, which involves pursuit of advanced research projects. High-enthalpy combustion wind tunnel Hypersonic wind tunnel Air flow around nose of rocket traveling at Mach 7 (flow is left to right) Education Program for Creativity in Transdisciplinary Sciences We cultivate individuals who can play an active role in emerging transdisciplinary frontiers Without being bound to any particular fields, we freely explore new methodologies and philosophies of our key activities: extracting spatial/temporal information from imaging, recognizing and conceptualizing information, and designing solutions through simulation. This is a short-term program (summer/ winter vacation) that supplements the core programs of all GSFS departments, and is designed to cultivate broad-minded individuals through a transdisciplinary curriculum. We also plan and hold the symposium series called Transdisciplinary Visualization Square (TV-Square), and provide a platform for the innovation of new integrated research fields. RT-1 plasma confinement device Kanon, a 4WD electric vehicle Hypersonic high-enthalpy wind tunnel at Kashiwa Campus 4 5

4 Division of Biosciences The 21st century dubbed the era of bioscience is ushering in new trends in medicine, agriculture, and other realms as fresh insights and discoveries revolutionize our understanding of life. This Division cultivates the individuals who will pioneer the new field of life sciences. Department of Integrated Biosciences We explore new frontiers by fusing leading-edge fields in the life sciences! The Department of Integrated Biosciences investigates the fundamental pro cesses and associated mechanisms of life phenomena based on genomic information, and uses the knowledge gained from this research to examine the universality and diversity of life,the cooperativeness and competitiveness of organisms,the origin and evolution of life, and other such themes from the perspective of structure and function. Our Group of Biosciences on Structural Aspects, which takes the structural approach, conducts investigative and applied research on the basic principles behind life phenomena, concentrating on the form and composition of biopolymers the fundamental molecules of life forms and the lowmolecular weight organic compounds that interact with them. Taking the perspective of function, our Group of Biosciences on Functional Aspects focuses mainly on the action and capabilities of organisms as it seeks to shed light on unknown complex biofunctions by analyzing them from various points of view, from the molecular and cellular level to the tissue and the individual. In order to provide a program of research and education that stays in stride with the rapid growth of the biosciences, our faculty is comprised of diversely experienced individuals from preexisting university departments, including Science, Agriculture, Engineering, and Medicine. Guided by the agreed principle that our research and education should be groundbreaking, transdisciplinary endeavors, we strive to cultivate individuals who will contribute to the resolution of bioscientific challenges, and to create next-generation biosciences that will explore life from the molecule to the individual through a full array of research, from basic to applied. The biosciences are now called upon to blaze a trail for the post-genomic era, and an indispensable part of fulfilling that task is to pool the knowledge and expertise of scientists from a variety of academic backgrounds. The Kashiwa Campus, founded on the concepts of intellectual adventure and transdisciplinarity, is just the right place for meeting this challenge of the times. As genomic bioscience continues to rapidly evolve in a world that is becoming increasingly advanced and complex, society s need for bioscientists and the social mission of bioscientists are both expected to grow and diversify in the years ahead. The Department of Integrated Biosciences is committed to fostering individuals who can contribute to the formation and advancement of new fields in bioscience, meaning scientists who are inspired with the pioneering spirit and possess a creative flair. Such talent is not something that is passively acquired; instead, it can only arise when the student takes an active approach to research. Accordingly, our key philosophy is to provide education that promotes an active attitude, and thus we encourage students to pursue originality in a manner that capitalizes on their individual qualities. Our educational program, which emphasizes the basics as much as it does the specialties, is designed to cultivate the power to think logically, communication skills, and the drive to take up new challenges, with the goal of nurturing future scientists who will pioneer new fields that transcend established disciplines. For example, we require students to take Breakthrough Now and Then, a practicum that equips them with the competencies essential for engaging in science, from drafting research proposals to presenting study results, and to take Bioethics, a course that examines science ethics against the backdrop of science s rapid development. Also, our Lessons in Writing Scientific Papers in English and Practice in Oral Presentation in English hone the abilities needed to write papers in English and make presentations at conferences outside Japan. In addition to such fundamental courses as these, our department further strives to provide an appealing graduate study program by giving students the opportunity to acquire a transdisciplinary perspective unfettered by the limits of conventional learning. Moreover, the Life Science Common Lecture and the Postgraduate Common Seminar of Life Science that we offer in cooperation with other graduate bioscience programs of the University of Tokyo are designed to strongly spark students intellectual curiosity. Another big feature of our department is that we have our entire teaching staff attend every master s interim oral presentation, master s thesis defense, and preliminary doctoral exam to provide their assessments and guidance. We have found that many of our students are inspired to rethink their research when they receive advice from instructors in fields outside their advisor s specialty. Laboratories Molecular medicine Molecular recognition Biochemistry of cell responsiveness Signal transduction Innovational biology Genome stability Plant life systems Evolutionary anthropology Bioresource regulation Bioresource technology Plant cell biology in totipotency Advanced cancer biology (National Cancer Center) Applied bioresource sciences (National Institute of Agrobiological Sciences) Isotope Ecology (The University Museum, The University of Tokyo) Advanced Marine Biosciences (Atmosphere and Ocean Research Institute, The University of Tokyo) Evolution and Development (Institute of Molecular and Cellular Biosciences, The University of Tokyo) Dynamic organizations of microtubules (green) and vacuolar membranes (red) during cell division in a tobacco BY-2 cell Department of Computational Biology and Medical Sciences The Background and Concept of Establishing a Novel Major by Merging Two Majors Significant developments in molecular biology materialized in the second half of the 20th century, leading to rapid progress in the fundamental understanding of organisms, which are systems based on genomes. In response, the 21st century is being called the age of life innovation the age of applied life science. However, as biological phenomena are complex, they cannot be understood or applied simply by parsing them into numerous constituent molecules and fundamental processes and simplifying them in order to identify principles. Rather, it will be necessary to analyze complex biological phenomena as a whole, clarify the numerous elements that are involved and their relationships, and determine methods for their regulation. This is the kind of technological innovation that will be imperative in leading the way in the age of life innovation. The rapid advances in technologies for DNA sequencing, omics analysis, and imaging in recent years have enabled comprehensive analysis of a wide variety of biological macromolecules for the first time, and paved the way for the analysis of complex biological phenomena as a whole. Moreover, massive data analysis of biological molecules, which was simultaneously realized, was found to be the focal point of life innovation. In the age of information-oriented life science, the innovation of information technology will be essential for understanding the numerous elements that are involved in biological phenomena and their interrelationships, as well as examining their regulation. MGS Fundamental Exercise I Bio-IP Course We foster intellectual property experts required for biotech business! It is essential for development of the biotech industry to combine basic and applied research. This course, which belongs to the Department of Medical Genome Sciences, provides systematic education on Transomic networks Medicine has always been at the forefront of applied life science because of its urgent need, and there is no exception in the age of informationoriented life science. The marked progress being mage in the acquisition of personal genomes in humans has enabled the rapid estimation of mutations related to diseases, and its clinical applications are being investigated. In addition, due to the accumulation of a substantial amount of phenotypic information in the form of medical care information, humans are thought of as the most suitable subjects of research involving novel information technology. Accordingly, in the age of information-oriented life science, it is expected that the field of medical science will lead the development of other fields. Given this awareness of the modern age, the department of Medical Genome Sciences and the department of Computational Biology have been merged, resulting in the establishment of a unique new major that is unprecedented in Japan. The objectives of this new major are to lead the way in information-oriented life science while significantly contributing to life innovation, and to cultivate personnel capable of translating the results in the clinical setting. To this end, we believe that it is necessary to develop personnel with a novel specialty by actively employing onthe-job training in state-of-the-art informatics and medical science research settings and implementing a basic education environment for integrating information science and medical science. intellectual property (IP) strategy for industrializing results of basic research in biotech fields, and conducts empirical research on correlations between innovation creation and IP strategy in biotech and medical fields. Through these activities, we aim to foster superior human resources who can utilize IP in business situation with entire picture of biotech, IP law, and business. This kind of personnel is required not only in medicine, but also in other technical fields such as agricultural sciences, pharmaceutical sciences, environmental studies and biotechnology. The ideal objective of our new major, as the only major in Japan able to cultivate such personnel, is to extensively supply personnel who will contribute to information-oriented life science and life innovation while leading research in Japan in the 21st century, which has been called the age of applied life science. Group of Computational Biology Group of Medical Sciences Group of Innovation Policy Studies trna-mimicry proteins in eukaryotic genetic decoding Fascinated by genome analysis Zebrafish UV-sensitive cones marked with green fluorescent protein (GFP) Clockwise: Spider monkey, mouse, Drosophila melanogaster, white campion, budding yeast, silkworm moth Swallowtail larva changing its camouflage to mimic bird feces (top, 4th instar) and a leaf (bottom, 5th instar) Medical Genome Science Program Become a pioneering researcher who bridges the life sciences and modern medicine! This program, which forms the axis of the Department of Medical Genome Sciences curriculum, is designed to cultivate science and engineering students into life/medical science researchers and engineers who use advanced genomic life science to engage in research that leads to new frontiers in medical science and healthcare. Degree earners who complete this program are awarded a certificate of completion, and are looked on to play a leading role in research that transcends basic science fields to encompass translational research and research that integrates medicine with engineering and informatics. 6 7

5 Division of Environmental Studies This division develops individuals who can accurately respond to a variety of environmental issues by offering education and research programs that analyze the human environment from the perspectives of nature, culture, and society, and build the skills needed to develop policies and technologies that will benefit humankind s future. Department of Natural Environmental Studies We explore relationships between the natural environment and human activity to form a better environment Department of Environment Systems Developing and assessing systems for innovating the ideal 21st century environment The natural environment consists of two components:(1) the inorganic environment comprising the geosphere, the atmosphere, and the hydrosphere, and (2) the biological environment populated with living organisms, such as plants and animals. Together these two components provide a platform for biological activity by forming the global ecosystem, in which matter and energy are cycled between both sides. Moreover, this life-supporting system serves as the foundation for human existence and culture. Currently, human impacts disrupt ecosystem structures and functions, leading to considerable deterioration of the global environment. An effective response to this decline requires, firstly, the formulation of policies to protect the global ecosystem based on a suitable assessment of the interaction between the natural environment and human activity, including the understanding of natural environment s structures/functions and the state of their change. Secondly, the measures must be designed to fully tap into nature s own powers for sustaining the environment. The Department of Natural Environmental Studies engages in research on the global terrestrial and marine environments. We perform observations and surveys to illuminate and evaluate the natural environment s structures/functions and their processes of transformation due to human impacts. Our research is based on the feedback between theory and experiment: we construct theories directed to improve the environment, and then verify these theories with experiments and surveys. At the same time, we provide a balanced program of environmental education, which takes a practical, functional approach to building up research competencies through trial and error. Our goal is to prepare individuals capable of designing social systems, which will embrace this type of education. Production of artificial materials, discharge of wastes, and development of earth s surface, underground and ocean have significantly affected environment systems which are composed both by natural environments and human societies, and have degraded the wealth of ecosystems and the quality of life. To tackle and overcome these problems, it is important to understand material and energy cycles, and to clarify the interaction among sub-systems which constitute the environment system. In addition, it is highly expected to develop problem-solving methodologies and their application through detailed study by scientific and engineering approach together with the integration of economics, policy science, and international cooperation. The viewpoints of risks and safety are also of fundamental importance. Department of Environment Systems conducts researches and education to design and realize the sustainable societies by analyzing the interaction and relationship between human societies and natural environment, developing the model to represent the environment systems based on the detailed analyses, clarifying the causes of the problems using the systems model, and investigating the possible solutions and the way to manage the system. In our curriculum, lectures are categorized into two programs, the Environment Engineer Training Program and the Environment Manager Training Program. The former cultivates the engineering sense needed to find technical solutions to environmental challenges, while the latter develops the foresight needed when making political decisions or managing environmental risk as a government officer or a business manager. We also have a Fieldwork Exercise to help students to grasp the actual state of the environment, and a laboratory named Transition to a Cycle-Oriented Society, which we jointly offer with the National Institute for Environmental Studies. Extensive fieldwork on natural environmental studies (tidal flat of Tamagawa river mouth) Measurement of the biomass potential in a satoyama woodland (Kashiwa city, Chiba) Practice in marine studies (Otsuchi Bay, Iwate) Hydrogen production experiment Construction field of LNG underground storage Marine environment research Department of Ocean Technology, Policy, and Environment We aim to develop human resources who contribute to the resolution of 21st century challenges through the ocean english/index.html Department of Human and Engineered Environmental Studies We work to solve population aging-related challenges and realize a low-carbon society. Covering nearly 70% of the earth s surface, the ocean is expected to play a vital role in resolution of the various global challenges faced by 21st century society, including the need to preserve the environment and secure a renewable supply of food, water, resources, and energy. The Department of Ocean Technology, Policy, and Environment engages in the following areas of education and research,guided by its vision that the ocean is the foundation of Japan s existence and a critical source of international competitiveness for Japanese industries. Strengthening the supply of food, mineral resources, and energy through utilization of marine resources AUV Tri-TON 2 Ensuring safety and security by strengthening marine observation for supporting marine resource utilization, coastal disaster prevention, and maritime safety, and by gaining greater understanding of the global environment Human-environment coexistence necessary for sustainable development, oceanic recycling / creation, and low-environmental-impact or environmental- impact-reducing marine activities We endeavor to foster human resources capable of contributing to ocean-related policymaking, industrial development, and environmental protection through ocean technology policies and marine environment policies, using their strong expertise Field study of the Arctic sea routes and international perspective derived from study of marine resource development, marine energy utilization, marine environment preservation, and from their experience in conducting experiments in water tanks and field observations on / in the ocean. Our educational program includes efforts that transcend the boundaries of ocean-related fields, such as a course collaboratively taught with the Institute of Industrial Science.the Japan Agency for Marine- Earth Science and Technology, and participation in the University of Tokyo Ocean Alliance. Numerical simulation of gas hydrate generation in the pore of artificial sand layer Two of the most important challenges now facing industrialized nations are coping with population aging and reducing carbon emissions. Japan, as arguably the nation with the greatest expertise in addressing these two issues, is being relied upon to develop and commercialize the technologies needed to provide solutions. However, the challenges present an antinomy a step forward in resolving one entails a step backward with the other and hence, they cannot be conquered through conventional technological development focused on individual issues. Rather, diverse sets of technologies must be systematized, their impact on society must be evaluated, and social institutions must also be changed where necessary. Simultaneously, new independent Training on a cognitive motion type machine Experimental operation of On-Demand Bus technologies need to be developed to facilitate assessment using new types of indicators. The challenges posed by population aging include managing and improving health on a daily basis, enhancing medical and nursing care systems, upgrading the housing environment, encouraging social involvement, ensuring mobility, and providing assistance for everyday purchases. However, attempting to address them simply by augmenting existing technologies and systems is not a viable solution because it would lead to increased social cost and energy consumption. Hence, in the process of carrying out R&D for inno vative solutions, the effectiveness and impact of each research achievement must not only be weighed in terms of the primary goal improving the health and lifestyle of seniors but also be evaluated comprehensively across many social dimensions, including energy, information, logistics, and economy. As for efforts toward building a low-carbon society, the focus should be not on lowering energy consumption through efficiency enhancements to existing equipment and devices, but on conducting R&D to create new elemental and system technologies premised on the popularization of future energy supply/consumption systems, such as wind and solar power generation, smart grids, cogeneration, heat pumps, electric vehicles, and home fuel cells. Moreover, it is vital to assess the elements that directly consume energy, such as information systems and physical distribution, and to constantly take into consideration the total energy consumption of the overall system, including the effects of popularization over time. In our department, we integrate existing disciplines such as environmental science, informatics, and physics to pursue our research mission, which is to conduct R&D on the various elemental technologies necessary for realizing a low-carbon society and supporting its aging population, carry out system design for these technologies, evaluate the products of research through field testing, and share our solutions with society. 8 9

6 Department of Socio-Cultural Environmental Studies Cultivating designer for buildings and communities The cities in which we live are environments made up of not only communities of people, but also hardware in the form of buildings and civil infrastructure. Moreover, urban areas cannot exist independently of the natural environment. Accordingly, environmental protection and environment formation need to be understood in terms of the interrelationships between such diverse elements. In order to accomplish this task, the Department of Socio-Cultural Environmental Studies applies, at the departmental level, the Graduate School of Frontier Sciences guiding philosophy of maintaining a transdisciplinary approach to science. Our department comprises three core programs Society and Humanity, Spatial Planning and Design, Water and Material Cycle as well as the cooperative course Spatial Information Science. We engage in education and research on analysis, evaluation, prediction, creation, and management of physical and socio-cultural environments at the architectural, urban, regional, and global levels. By introducing a multi-faceted approach that covers the natural and socio-cultural sciences, we provide students with the ability to accurately deal with a variety of challenges in environmental studies. We also play the central role in the Integrated Environmental Design Program, which develops practical skills in comprehensive environmental design, and help to run the Environmental Management Program. In addition, we play the leading role in social outreach and educational Diorama and Design studio of the UDCK GIS-based analysis of public transport convenience activities conducted with the Urban Design Center Kashiwa-no-ha (UDCK). Sannai-Maruyama site: Re-creation of Jomon-era ecosystem Water cycle and human society: Harmonizing the ecosystem Division of Environmental Studies Graduate Program in Sustainability Science - Global Leadership Initiative Nurturing Global Leaders for Sustainable Society Humanity faces an array of serious and complex issues in the 21st century very wide-ranging such as climate change, biodiversity loss, disaster of extreme severity, resource depletion, poverty, and aging societies. The University of Tokyo has long been taking up the challenge of global sustainability through transboundary and holistic approaches with the establishment of the Integrated Research System for Sustainability Science (IR3S) and the Graduate Program in Sustainability Science (GPSS) since 2005, and has become a widely-recognized leader in research and education in Sustainability Science and in applying research findings in practical ways through collaborative partnerships beyond the university, so called Meta-Network. On the basis of its achievement, The Graduate Program in Sustainability Science Global Leadership Initiative (GPSS- GLI) has been launched in 2011 to train individuals who can be the next generation of global leaders in building sustainable societies. Global leaders require abilities that of having an overall perspective through understanding transdisciplinary and holistic approaches, and making proposals based on intensive specialization in a certain field and extensive knowledge across a variety of fields, and global leadership with effective communication skills gained by international and practical experience in various fields. These abilities will make a difference in enhancing the resilience of society against short-term risks associated with disaster of extreme severity, and long-term risks associated with climate change. To foster these abilities, our curriculum is designed around three clusters: 1) foundation and specialized courses covering key issues related to Sustainability Science; 2) diverse practical and theoretical exercises aimed at enhancing such skills as communication, systems thinking, social surveys, and data analysis through real world practical training and active discussion; and 3) a comprehensive research process, starting with identifying a research topic and progressing through research framework development to the production of a Master s thesis or Ph.D. dissertation. In addition, GPSS-GLI provides students with a variety of transdisciplinary opportunities concerning the latest general and technical developments in the academic field of Sustainability Science through the cooperation of other departments of the Graduate School of Frontier Sciences, other related departments/research institutes of The University of Tokyo, research and educational networks with domestic/international institutions developed in coordination with IR3S, in cooperation with the United Nations University and overseas leading universities especially those in Africa. Students are provided with plentiful opportunities through fieldwork, internships and interactive seminar by leaders from various fields in a variety of research areas by utilizing those networks English is the medium of communication in all lectures, in-class activities, fieldwork, and seminars. More than half of our students are non-japanese from Asia, Africa, Europe virtually every continent in the world with science, engineering, humanities and other backgrounds that represent a broad diversity of fields. Those students who want to apply for enrollment are required to take the special GPSS- GLI admission examination. Students who complete the Master program receive a Master of Sustainability Science, and those who complete the Doctoral program receive a Ph.D. in Sustainability Science. Field Exercise Active debate by students with various back ground Dialogue with leaders Department of International Studies Creating practical solutions to challenges surrounding development cooperation, environment and resources, and institutional building The world today faces a multitude of challenges tied to international cooperation, including development of developing countries, reduction of poverty, environmental destruction, resource management, international policy coordination, and global governance. The Department of International Studies broadly categorizes these challenges into three clusters Development Cooperation, Environment/ Resources, and Institutianal Building and engages in research and education for each cluster. Through our research and educational programs we seek to contribute to society by: (1) proposing and implementing specific strategies for solving or preventing issues, and (2) cultivating globally active leaders who possess solid skills in policymaking and practical management. The challenges for international cooperation cannot be successfully analyzed and resolved through efforts confined to a single discipline; instead, they require a transdisciplinary approach that adeptly fuses individual disciplines into a force for the creation of innovative knowledge. At the same time, these challenges need to be tackled with solutions that combine theory with practice, based on thorough field observation at the ground zero of the problems faced. Accordingly, our department has a diverse faculty members comprising experts in economics, engineering, agricultural science, sociology, political science, and other disciplines who pursue transdisciplinary research grounded in fieldwork. We also actively collaborate with Japanese and foreign governmental agencies, foreign aid institutions, and businesses to repay society with the products of our research. Our student body is also diverse, having a balanced mix of undergraduate degrees in both the humanities and science/engineering, and including a good number of international students from Asia, Africa, and other parts of the world. We also actively encourage working adults to enter our doctoral program, which includes many students who are current or former employees/members of development-related institutions and international organizations. Development cooperation Development/poverty issues in developing countries Environmental Management Program Gain the skills needed for environmental technology management This program in management of environmental technologies is designed for those who comprehensively study, conceive, and develop those technologies and who are interested in technology transfer and commercialization, including persons not affiliated with the GSFS Division of Environmental Studies. Management of technology is the art of managing creative, strategic innovation to enable technologyfocused businesses and organizations to achieve sustainable growth through constant creation of next-generation enterprises. Integrated Environment Design Program Six design studios for creating environmental design professionals Environmental designers in this century must possess not only the technologies for creating new environments, but also the skills for cultivating, maintaining, and managing those environments. Guided by the GSFS founding principle of transdisciplinarity, this program s six design studios provide practical education aimed at fostering environmental design professionals who are equipped with a wide spectrum of knowledge that goes beyond the traditional walls of specialization. Environment Engineer Training Program Equip yourself with engineering sense for solving environmental challenges! The Department of Environment Systems offers this program to help students to cultivate engineering sense to tackle environmental challenges with technology, which will be useful when they work as an engineer at companies and research institutions in the future. The curriculum includes not only regular lectures but also a fieldwork practicum. Curriculum keywords: Environmental technology, Energy and resources, Environment material systems, Environment chemical engineering, Environmental simulations, Material-reaction systems. Interviewing rural villagers Forming social networks among farming communities in developing countries Institutional Building International policy coordination, global governance Environment & resources Transnational environmental issues, resource management issues Challenges for international cooperation Environment Manager Training Program Polish your sense for environmental policymaking and risk management! This program intends to polish the sense needed for students who wish to engage in environmental policymaking and environmental risk management at national/local government agencies and companies. A certificate of completion is awarded to those who complete the required courses specified by the Department of Environmental Systems. Like the Environment Engineer Training Program, its curriculum includes a fieldwork. Curriculum keywords: Social systems, Environmental risk, Environmental economy, Environment safety, Natural systems, Environmental ecology, Geosphere environment, Life cycle assessment

7 Facilities Research Center for Total Life Health and Sports Sciences Seeking to foster long, healthy lives through sports The rapid aging of Japan s population amidst a drop in the birthrate has given rise to a number of problems that require an urgent response, including increased efforts to prevent lifestyle-related diseases and to keep the elderly from becoming bedridden. Consequently, one of the most critical challenges faced by modern society is to promote lifelong health and transform the populace into a community of physically independent, long-living individuals. The Research Center for Total Life Health and Sports Sciences performs an extensive array of practical and applied studies with the aim of widely using the achievements of this research to benefit society by aiding athletes of all ages, as well as members of the general public, including children, adolescents, middle- aged adults, seniors, and those with weakened functional fitness. Specifically, we seek to help such people to enhance their physical abilities; maintain a healthy, active lifestyle; and enjoy a mentally and Visualization of invisible molecules has often led to scientific breakthroughs. Especially, in the life sciences, there is a strong need to elucidate the molecular reactions as clues for understanding of visible cellular processes and the integrated systems of tissues and organisms. Bioimaging is an attempt to collect the extensive information of molecules through visualization and thereby get information about precise biological systems. In order to understand complex biological phenomena, it is necessary to extract the essential information from the vast amount of information related to complex phenomena. In the GSFS, there are many outstanding individuals who cover a wide spectrum of research fields, including bioresearchers who investigate research topics concerning molecules, cells, tissues, and organisms, specialists who study the mathematics-based processing physically satisfying quality of life. As one example of our efforts to promote good health through community cooperation, we have set up Totsubo Gyms across the country as fitness centers designed to provide seniors with physical conditioning through cognitive-motion training machines. In addition, we Nordic walking in older persons Center for Omics and Bioinformatics A future-oriented genomics research center that leads the era of Genome Big Bang Omics is a new research field that gleans and analyzes all the biological data obtained from research in genomics, proteomics, and related disciplines to decipher complex biological processes. Global advances in ultra-fast DNA sequencing technology are dramatically revolutionizing the life sciences by accelerating biological data acquisition and analysis by two or more orders of magnitude over what was previously possible. The Center for Omics and Bioinformatics was established at the GSFS to lead the way in this revolution as a facility equipped with some of Japan s strongest capabilities in data production and informatics analysis. By developing various measurement/information fusion technologies, we strive to blaze new paths in omics researches, including genomics, transcriptomics, Bioimaging Center A research center that studies biological phenomena through visualization metagenomics, and epigenomics. We also endeavor to be a center for future-oriented genomics by taking a transdisciplinary approach beyond life science field to encompass other disciplines, engaging in of biological information, and faculty members who develop advanced devices for observation of biological phenomena. The center was established in 2009 to bring together such pioneers and use their combined knowledge to elucidate the workings of complex, dynamic biological phenomena through bioimaging. Covering the four areas listed below, eighteen faculty members from seven GSFS departments are involved in the center s efforts to explore new research fields with a transdisciplinary approach. While building close cooperation between our four units, we also seek to serve as a new driving force for university-wide collaboration and for joint research with extramural research centers. At the same time, we implement educational programs designed to cultivate researchers with wide-ranging knowledge. are actively engaged in helping to build a cheerful society of healthy, energetic seniors through our Kashiwa Wellness Village Project, which is a program that researches methods for aiding middle-aged and elderly people to exercise regularly and manage properly their dietary intake. Exercise under simulated oxygen conditions university-wide collaboration, and supporting or jointly conducting research involving partner institutions outside the university. Center for Omics and Bioinformatics Pioneering and advancing new fields in genomics and computational biology Next-generation sequencers, bioinformatics, joint research, analysis support Metagenomics Genome sequencing Transcriptome analysis High-speed informatics Division of cellular imaging Epigenome analysis Human genome resequencing Division of molecular imaging Division of mathematical biology Division of whole-body and tissue imaging Functional Proteomics Center Working together to build the foundation for drug discovery TJCC (Todai-JAXA Center for Composites) Seeking to create a science of intelligent manufacture of innovative composite structures Japan is a world leader in the ability to manufacture and develop carbon fiber reinforced plastic (CFRP) for aerospace applications. Because of intense international competition, however, it is necessary to further set apart Japanese CFRP production technologies and achieve high value-added for them by advancing Japan s own brand of research and development with even stronger backing by science platforms. The Todai-JAXA Center for Composites (TJCC) utilizes distinctive advanced visualization technologies (such as fiber optic sensor networks) and computational science to expand technologies for manufacturing composite structures as it strives to create intelligent manufacturing science for Japan-style research and development that is supported by strong scientific platforms and does not Campus Life The Kashiwa Library on Kashiwa Campus offers students such amenities as spacious reading rooms and a media hall where various lectures are held. The university plans to open up a new welfare facility at Kashiwa Campus and a sports facility at Kashiwa II Campus. The Tsukuba Express has been increasing its daily number of runs, and the area around Kashiwanoha Campus Station is being developed steadily. The buildup of the surrounding community promises to make Kashiwa Campus part of the University of Tokyo s tripolar structure even more attractive as a center for education and research. The Functional Proteomics Center (FPXC) aims to develop technologies for efficient discovery of protein function-controlling low molecular weight compounds by combining elemental technologies in leading-edge protein functional analysis and by creating new protein functional analysis technologies, and to apply those technologies to various targets. The FPXC pursues research that integrates target identification, protein production, interaction analysis, low molecular weight screening, informatics-based interaction prediction, and so forth, and plans to engage in research and development of equipment and informatics methodologies that can increase analysis throughput and lower costs. In addition to conducting basic research, the FPXC is looking to become directly involved in the drug discovery process by coordinating research with equipment manufacturers, pharmaceutical companies, and biotech firms. depend on trial and error. Through this pursuit, the TJCC aims to strengthen the might of the aircraft industry (expanded application of CFRP to aircraft fuselages and engines), aid the development of a low-carbon society (reduction of the weight of aircraft, automobiles, ships, etc.), and improve safety and security of society (enhancing the reliability of aircraft, automobiles, ships, etc.). Specifically, the TJCC pursues research on three themes that respond to the needs of industry and may evolve into scientific frontiers: (1) molding and curing; (2) processing and strength assessment; and (3) maintenance and management (life cycle : quality assurance from molding/manufacturing to operation). Curing Non-uniform temperature Optical fiber network Temperature, flow and/or cure Cooling and demolding Distortion Residual strain Lay-up Life cycle Assembly Joints Product life cycle, from launch to retirement Deformation Operation Usage and health Strain Damage 12 13

8 14 15

9 Kashiwa Campus Guide Transdisciplinary Sciences, GSFS Transdisciplinary Sciences Laboratory, GSFS TJCC (Todai-JAXA Center for Composites) Biosciences, GSFS Bioimaging Center Environmental Studies, GSFS Functional Proteomics Center Kashiwa Research Complex Kashiwa Library Institute for Solid State Physics Labs Kashiwa Research Complex 2 Atmosphere and Ocean Research Institute Parking Administrative Office, GSFS (1st floor) Plaza Ikoi Institute for Solid State Physics (ISSP) Kavli Institute for the Physics and Mathematics of the Universe Institute for Cosmic Ray Research Food Shop & Cafe, Cafeteria Parking Parking Parking Computational Biology Laboratory, GSFS Center for Omics and Bioinformatics Todai-nishi Gatehouse Todai-mae Kashiwanoha Koen Kita Main gate National Cancer Center Todai-nishi Todai-mae Kashiwanoha Koen Kita Kashiwa Campus Kashiwa Interchange Joban Expressway 16 National Cancer Center To Tsukuba Kashiwatanaka Sta. Kashiwa II Campus Research Center for Total Life Health and Sports Sciences to Kashiwa Campus ACCESS From Kashiwa Interchange: Exit the Joban Expressway s Kashiwa Interchange via the Chibabound exit and get on National Road 16. Travel 500 meters to the intersection named Toyofuta Industrial Estate Entrance and turn right. Kashiwa Campus is one kilometer from this intersection, on the right. To Hatsuishi To Akihabara 47 Tsukuba Express Kashiwanoha Park Nagareyama- Otakanomori Sta. Toyoshiki Sta. 47 Tobu Noda Line Kashiwanoha Campus Sta. To Tokyo 16 6 To Ueno 7 To Mito JR Joban Line Kashiwa Sta. Tsukuba Express From Kashiwanoha Campus Station: Shuttle bus Kashiwanoha Campus Station to Kashiwa Campus Regular bus lines (Tobu Bus stop no. 1 outside West Exit) Nishi-Kashiwa 03, bound for East Exit of Nagareyama-Otakanomori Station Nishi-Kashiwa 04, bound for East Exit of Edogawadai Station Nishi-Kashiwa 10, bound for East Exit of Edogawadai Station Get off at the Todai-mae or Todai-nishi stop. Taxi Approx. 5-minute ride from the West Exit of Kashiwanoha Campus Station JR Joban Line / Tobu Noda Line From Kashiwa Station: Regular bus lines (Tobu Bus stop no. 2 outside West Exit) Nishi-Kashiwa 01, bound for National Cancer Center (via Kashiwanoha Park) Get off at the Todai-nishi or Todai-mae stop. Taxi Approx. 20-minute ride from the West Exit of Kashiwa Station Administrative Office, Graduate School of Frontier Sciences Kashiwanoha, Kashiwa-shi, Chiba-ken TEL: FAX:

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