Calibration Verification/Linearity and Instrumentation

Transcription

1 Calibration Verification/Linearity and Instrumentation s/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS). Your Total Calibration Verification/Linearity (CVL) Solution Calibration Verification/Linearity Survey Corresponding Survey Survey Validated Material LN1-Chemistry CVL C1, C3, CZ LN2ERVM LN1ER-Chemistry Extended Range CVL C1, C3, CZ LN2ERVM LN2-Chemistry/Lipid/Enzyme CVL C1, C3, CZ LN2ERVM LN2ER-Chemistry/Lipid/Enzyme/Extended Range CVL C1, C3, CZ LN2ERVM LN3-TDM CVL CZ, Z CZVM LN5-Ligand Assay CVL K, KK, KN LLM LN6-Urine Chemistry CVL U LUM LN7-Immunology CVL IG - LN8-Reproductive Endocrinology CVL Y, YY - LN9-Hematology CVL FH Series, HE Series - LN9ER-Hematology Extended Range CVL FH Series, HE Series - LN11-Serum Ethanol CVL AL2 - LN11ER-Serum Ethanol Extended Range CVL AL2 - LN12-C-Reactive Protein CVL CRP - LN13, LN13C-Blood Gas/Critical Care CVL AQ, AQ2 - LN14-Whole Blood Ethanol CVL AL1 - LN15-Glycohemoglobin CVL GH2 - LN16-Homocysteine CVL HMS - LN17-Whole Blood Glucose CVL WBG, WB2 - LN18-Reticuloctye CVL RT, RT2, RT3, RT4 - LN19-Reticulocyte CVL RT3 (Coulter GenS and LH700 series only) LN20-Microalbumin CVL U (Microalbumin and Creatinine) - LN21-High-Sensitivity C-reactive Protein CVL hscrp - LN22-Flow Cytometry CVL FL - LN23-Prostate-Specific Antigen CVL K (PSA) - LN24-Creatinine Accuracy CVL C1, C3, CZ - LN25-Troponin I CVL TRP, CRT - LN26-Troponin I CVL TRP (Abbott AxSYM only) - LN27-Troponin T CVL TRP, CRT (Troponin T) - LN28-Adjustable Micropipette CVL - - LN30-B-type Natriuretic Peptides CVL BNP - LN31-Immunosuppressive Drugs CVL CS - LN32-Ammonia CVL NEW - - LN33-Serum Myoglobin CVL NEW CARM, CRT, CARMI, CRTI - LN34-CA-125 CVL NEW TM - Provides individual evaluation reports by analyte, executive summary report, and graphical plots for linearity and calibration verification Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 77

2 Option 1 # for Customer Contact Center Calibration Verification/Linearity Surveys advantages: Receive liquid specimens that cover broad analyte ranges to challenge assays from near zero to the top of the analytical measurement range for most analytes and methods Access a comprehensive selection of analytes and programs to encompass a broad testing menu Satisfy the requirements for scheduled verification of the analytical measurement range of the CAP Laboratory Accreditation Program and the CLIA calibration verification under 42 CFR (b)(3) for most analytes Use a consistent analytical approach for the assessment of the method linearity and calibration agreement with your peer group Get custom reports with an Executive Summary for a quick overview of the performance, a Comprehensive Evaluation Report with specific analyte information, and Linearity & Calibration/Verification graphs Note: The College of American Pathologists Laboratory Accreditation Program requires an additional calibration verification process for methods calibrated less frequently than once every six months. Please review the inspection checklist for information about suitable verification material for any method that is calibrated less often than at six-month intervals. The Calibration Verification/Linearity Surveys are designed to assess agreement of a laboratory with the method manufacturer s calibration settings, but do not validate accuracy traceable to reference methods. Please see the CAP Standards and Instrumentation Resource Committee Web site at or contact a CAP Customer Contact Center Representative at option 1 # for additional information and a listing of the specific analyte ranges targeted in these Surveys. Improve the reliability of your patient results with CAP Survey Validated Materials Use the same material that is sent in the Surveys Program to: Identify and troubleshoot instrument/method problems Correlate results with other laboratories or instruments Document correction of problems identified in Surveys Utilize as an alternative external quality control material with confirmed results Results are readily available in the Survey Participant Summary that is included with each Survey Evaluation Report. 78 Calibration Verification/Linearity and Instrumentation College of American Pathologists

3 Chemistry/Lipid/Enzyme Calibration Verification/Linearity LN1, LN1ER, LN2, LN2ER LN1 LN1ER LN2 LN2ER Albumin Bilirubin, direct Bilirubin, total* Calcium* Chloride CO 2 * Creatinine Glucose Iron Magnesium Osmolality* Phosphorus Potassium Protein, total Sodium Urea Uric Acid Alanine aminotransferase (ALT/SGPT) Alkaline phosphatase (ALP) Amylase Aspartate aminotransferase (AST/SGOT) Cholesterol* CK 2 (MB) Creatine kinase (CK) Gamma glutamyl transferase (GGT) HDL cholesterol* Lactate dehydrogenase (LD) Lipase Triglycerides* Auto dilutor validation report NEW CVL CHEMISTRY/LIPID/ENZYME VALIDATED MATERIAL (LN2ERVM) $594 *These analytes are not available for extended range reporting. New for 2007: LN1 and LN2 participants will be allowed to report auto diluted specimen results. A report will be provided that may be used to verify that the auto dilutor is working appropriately. Surveys LN1 and LN2 correspond to CAP Chemistry Surveys C1, C3, and CZ. Each shipment of Surveys LN1 and LN2 will contain six 10.0-mL liquid serum specimens and six 3.0-mL liquid serum specimens for evaluation of direct and total bilirubin. Each shipment of Survey LN2 will also contain one 20.0-mL and two 10.0-mL liquid lipid serum specimens from which additional admixtures will be prepared. Survey LN1ER will include all specimens in LN1 and an additional high vial for participants that need higher analyte ranges than currently available in Survey LN1. Survey LN2ER will include all specimens in LN2 and an additional high vial for participants that need higher analyte ranges than currently available in Survey LN2. Note: The extended range vial (LN1ER and LN2ER) will be evaluated for calibration verification only. Each set of LN2ERVM ordered will contain all the specimens included in LN2ER. Shipment A June 18 Shipment B December Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 79

4 Option 1 # for Customer Contact Center Survey LN3 corresponds to CAP General Chemistry and Therapeutic Drug Monitoring Surveys CZ and Z. Each shipment of Survey LN3 will include six 4.0-mL liquid serum specimens. Each set of LDM ordered will consist of six 4.0-mL liquid serum specimens. Shipment A May 7 Shipment B November 5 TDM Calibration Verification/Linearity LN3 LN3 Acetaminophen Amikacin Carbamazepine Digoxin Gentamicin Lidocaine Lithium N-acetylprocainamide (NAPA) Phenobarbital Phenytoin Primidone Procainamide Quinidine Salicylate Theophylline Tobramycin Valproic acid Vancomycin CVL TDM VALIDATED MATERIAL (LDM) $202 Survey LN5 corresponds to CAP Ligand Assay (General) Surveys K, KK, and KN. Each shipment of Survey LN5 will include five 4.0-mL liquid serum specimens. Each set of LLM ordered will consist of five 4.0-mL liquid serum specimens. Shipment A June 4 Shipment B November 26 Ligand Assay Calibration Verification/Linearity LN5 LN5 CEA Cortisol Ferritin Folate Human chorionic gonadotropin (hcg) T3, total (Triiodothyronine) T4, total (Thyroxine) Thyroid-stimulating hormone (TSH) Vitamin B 12 CVL LIGAND ASSAY VALIDATED MATERIAL (LLM) $204 College of American Pathologists 80 Calibration Verification/Linearity and Instrumentation

5 Urine Chemistry Calibration Verification/Linearity LN6 Amylase Calcium Chloride Creatinine Glucose Osmolality Phosphorus Potassium Protein, total Sodium Urea Uric acid Auto dilutor validation report NEW LN6 CVL URINE CHEMISTRY VALIDATED MATERIAL (LUM) $230 New for 2007: LN6 participants will be allowed to report auto diluted specimen results. A report will be provided that may be used to verify that the auto dilutor is working appropriately. Survey LN6 corresponds to CAP Urine Chemistry (General) Survey U. Each shipment of Survey LN6 will include ten 4.0-mL liquid urine specimens. Each set of LUM ordered will consist of ten 4.0-mL liquid urine specimens. Shipment A May 7 Shipment B November 5 Alpha-1-antitrypsin Complement C3 Complement C4 IgA IgG IgM Transferrin Immunology Calibration Verification/Linearity LN7 LN7 PRICE $376 Survey LN7 corresponds to CAP Immunology (General) Survey IG. Each shipment of Survey LN7 will include five 2.0-mL liquid serum specimens. Shipment A April 9 Shipment B October Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 81

6 Option 1 # for Customer Contact Center Estradiol Follicle-stimulating hormone (FSH) Human chorionic gonadotropin (hcg) Luteinizing hormone (LH) Progesterone Prolactin Testosterone Reproductive Endocrinology Calibration Verification/Linearity LN8 PRICE $376 LN8 Survey LN8 corresponds to CAP Ligand Assay (Special) Surveys Y and YY. Each shipment of Survey LN8 will include five 4.0-mL liquid serum specimens. Shipment A April 10 Shipment B October 1 Hematology Calibration Verification/Linearity LN9, LN9ER LN9 LN9ER Hemoglobin Platelet count RBC count WBC count PRICE $596 $624 Surveys LN9 and LN9ER correspond to the CAP Basic Hematology and Hematology Automated Differentials Surveys HE and FH series. Surveys LN9 and LN9ER are compatible with all instruments. The Surveys provide an indicator of platelet accuracy at clinical decision levels. The specimens are designed to span the linear range of most automated hematology instruments. Each shipment of LN9 will include mL specimens. Survey LN9ER will include all specimens in LN9 and four additional high vials for participants that need higher platelet and WBC ranges than currently available in Survey LN9. Note: The extended range vial will be evaluated for calibration verification only. All vials have pierceable caps. Shipment A April 10 Shipment B October 1 82 Calibration Verification/Linearity and Instrumentation College of American Pathologists

7 Serum Ethanol Calibration Verification/Linearity LN11, LN11ER LN11 LN11ER Serum Ethanol PRICE $338 $350 Surveys LN11 and LN11ER correspond to the AACC/CAP Serum Alcohol/Volatiles Survey (AL2). Each shipment will contain six 3.0-mL liquid serum specimens. Survey LN11ER will include all specimens in LN11 and one additional high vial for participants that need higher analyte ranges than currently available in Survey LN11. Note: The extended range vial will be evaluated for calibration verification only. Shipment A January 29 Shipment B August 6 C-reactive Protein Calibration Verification/Linearity LN12 LN12 C-reactive protein PRICE $318 Each shipment of Survey LN12 will include six 1.0-mL liquid serum specimens. Note: This Survey is not designed for reporting high-sensitivity C-reactive protein. Shipment A January 29 Shipment B August Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 83

8 Option 1 # for Customer Contact Center Blood Gas/Critical Care Calibration Verification/Linearity LN13, LN13C LN13 LN13C PCO2 ph PO2 Calcium, ionized Chloride Glucose Lactate Magnesium, ionized Potassium Sodium PRICE $404 $486 Survey LN13 corresponds to the blood gas component of the CAP Critical Care Aqueous Blood Gas AQ/AQ2 Surveys. Survey LN13C corresponds to the electrolyte and blood gas components of the AQ/AQ2 Surveys. Each shipment of Survey LN13 and LN13C will include ten 2.5-mL ampules of aqueous specimens (five in duplicate) for single instrument reporting. Shipment A January 29 Shipment B August 6 Whole Blood Ethanol Calibration Verification/Linearity LN14 LN14 Ethanol PRICE $392 Survey LN14 corresponds to the AACC/CAP Alcohol/Volatiles Survey (AL1) for whole blood analysis of ethanol. Each shipment of Survey LN14 will include six 3.0-mL liquid whole blood specimens. Shipment A January 29 Shipment B August 6 84 Calibration Verification/Linearity and Instrumentation College of American Pathologists

9 Glycohemoglobin Calibration Verification/Linearity LN15 LN15 Glycohemoglobin (HbA 1c ) PRICE $414 Survey LN15 corresponds to the CAP GH2 Survey for glycohemoglobin. Each shipment of Survey LN15 will include six 0.7-mL liquid human whole blood specimens. Note: These specimens must be processed as patient specimens, and tested as soon as possible after they are received. Shipment A March 6 Shipment B October 16 Homocysteine Calibration Verification/Linearity LN16 LN16 Homocysteine PRICE $542 Survey LN16 corresponds to the CAP HMS Survey for homocysteine. Each shipment of Survey LN16 will include six 1.0-mL liquid serum specimens. Shipment A March 12 Shipment B September 17 Whole Blood Glucose Calibration/Verification Linearity LN17 LN17 Whole blood glucose PRICE $262 Survey LN17 corresponds to the CAP WBG/WB2 Surveys for whole blood glucose. With each kit, you may report from ten different ancillary testing sites or instruments. Each shipment of Survey LN17 will include five 2.0-mL liquid whole blood specimens. Shipment A March 12 Shipment B September Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 85

10 Option 1 # for Customer Contact Center Reticulocyte Calibration Verification/Linearity LN18, LN19 Instrument LN18 LN19 All instruments except Coulter GenS and LH700 series Coulter GenS and LH700 series Pierceable caps PRICE $416 $416 Survey LN18 corresponds to the CAP RT, RT2, RT3, and RT4 Surveys for all instruments except the Coulter GenS and LH700 series. Survey LN19 corresponds to the RT3 Survey for Coulter GenS and LH700 series users only. Each shipment of Surveys LN18 and LN19 will include five 1.0-mL red blood cell specimens. Shipment A March 26 Shipment B October 8 Microalbumin Calibration Verification/Linearity LN20 LN20 Microalbumin Creatinine PRICE $312 Survey LN20 corresponds to CAP Urine Chemistry Survey U. Each shipment of Survey LN20 will include five 5.0-mL liquid urine specimens. Shipment A April 10 Shipment B October 1 High-sensitivity C-reactive protein High-Sensitivity C-reactive Protein Calibration Verification/Linearity LN21 LN21 PRICE $338 Survey LN21 corresponds to the CAP High-Sensitivity C-reactive Protein Survey hscrp. Each shipment of Survey LN21 will include six liquid serum specimens. Survey LN21 is for high sensitivity methods only. Shipment A April 10 Shipment B October 1 86 Calibration Verification/Linearity and Instrumentation College of American Pathologists

11 Flow Cytometry Calibration Verification/Linearity LN22 LN22 CD3+ CD3+/CD4+ CD3+/CD8+ PRICE $636 Survey LN22 corresponds to the CAP Flow Cytometry Survey FL. Each shipment of LN22 will include seven 1.0-mL liquid whole blood specimens. Shipment A April 2 Shipment B October 8 Prostate-Specific Antigen Calibration Verification/Linearity LN23 Prostate-Specific Antigen LN23 PRICE $812 Survey LN23 corresponds to the CAP Ligand Assay Survey K. Each shipment of LN23 will include twelve 1.0-mL liquid serum specimens. The first seven vials will consist of values specified at a range from ng/ml. Vials eight through twelve will consist of values specified at a range from ng/ml. Shipment A May 21 Shipment B November 26 Creatinine Accuracy Calibration Verification/Linearity LN24 LN24 Creatinine PRICE $382 The LN24 Survey focuses on values for creatinine at the range from mg/dl. Each shipment of LN24 will consist of seven 1.0-mL liquid fresh frozen serum specimens. Shipment A May 21 Shipment B November Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 87

12 Option 1 # for Customer Contact Center Troponin I Calibration Verification/Linearity LN25, LN26 Instrument LN25 LN26 All instruments except Abbott AxSYM Abbott AxSYM PRICE $652 $652 Surveys LN25 and LN26 correspond to the CAP Troponins I and T Survey TRP. Each shipment of LN25 will consist of seven 2.0-mL liquid serum specimens. Each shipment of LN26 will consist of five 2.0-mL liquid serum specimens. Note: The specimens must be processed and tested as soon as possible after they are received. Shipment A March 26 Shipment B September 24 Troponin T Troponin T Calibration Verification/Linearity LN27 LN27 PRICE $652 Survey LN27 corresponds to the CAP Troponins I and T Survey TRP. Each shipment of LN27 will consist of six 2.0-mL liquid serum specimens. Note: The specimens must be processed and tested as soon as possible after they are received. Shipment A March 26 Shipment B September 24 Adjustable Micropipette Calibration Verification/Linearity LN28 Challenge LN28 Adjustable Micropipette PRICE $250 Survey LN28 is designed to calibrate up to five adjustable micropipettes using a spectrophotometer or microtiter plate reader. Survey LN28 will consist of a 20.0-mL chromophore vial. Shipment A April 2 Shipment B December 3 88 Calibration Verification/Linearity and Instrumentation College of American Pathologists

13 B-type Natriuretic Peptides Calibration Verification/Linearity LN30 LN30 BNP NT-pro BNP PRICE $422 Survey LN30 corresponds to the CAP B-type Natriuretic Peptides Survey BNP. Each shipment of LN30 will include six 1.0-mL liquid plasma specimens for BNP and NT-pro BNP. A seventh 1.0-mL liquid plasma specimen will be included to test only for NT-pro BNP. Note: Linearity Surveys have linearity targets based on clinical relevance and general characteristics of currently available methods. These criteria may not be reflective of the specific characteristics of the currently available single dose unit technology methods. For customers using single dose unit technology, it is the laboratory's discretion to assess the appropriateness of the linearity targets when applied to this technology and to the clinical needs of their patients Shipment A June 11 Shipment B December 10 Immunosuppressive Drugs Calibration Verification/Linearity LN31 Cyclosporine Tacrolimus LN31 PRICE $852 Survey LN31 corresponds to the CAP Immunosuppressive Drugs CS Survey. Each shipment of LN31 will include seven 2.0-mL liquid EDTA plasma specimens. Shipment A February 26 Shipment B August Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 89

14 Option 1 # for Customer Contact Center New Ammonia Calibration Verification/Linearity LN32 LN32 Ammonia PRICE $422 Each shipment of LN32 will include seven 2.0-mL liquid specimens. Shipment A May 21 Shipment B November 19 New Serum Myoglobin Calibration Verification/Linearity LN33 LN33 Myoglobin PRICE $422 Survey LN33 corresponds to the CAP Cardiac Markers CARM, CRT, CARMI, and CRTI Surveys for quantitative myoglobin. Each shipment of LN33 will include seven 1.0-mL liquid specimens. Shipment A May 21 Shipment B November 19 New CA-125 Calibration Verification/Linearity LN34 LN34 CA-125 PRICE $422 Each shipment of LN34 will include seven 3.0-mL liquid specimens. Shipment A April 23 Shipment B September 4 90 Calibration Verification/Linearity and Instrumentation College of American Pathologists

15 Reference Range Service RRS, RRS2 RRS RRS2 RRS RRS2 Alanine aminotransferase B-type Natriuretic Peptides (BNP) Albumin Pro B-type Natriuretic Peptides (NT-pro BNP) Amylase Chloride Aspartate aminotransferase CO 2 Bilirubin, total C-reactive Protein (CRP) Calcium Folate CK-MB Gamma Glutamyl Transferase (GGT) Creatinine Glucose Ferritin Potassium T 4, free (thyroxine, free) Sodium Iron Testosterone Lactate dehydrogenase Thrombin Time (TT) Magnesium Uric Acid Protein, total Urea T 4 (thyroxine) Vitamin B-12 Total iron binding capacity Thyroid stimulating hormone (TSH) PRICE $243 New The Reference Range Service (RRS and RRS2) is designed for laboratories/laboratory networks to provide a method to establish and/or verify the validation of reference intervals based on the NCCLS Reference Range Protocol C28-A2, Vol. 15, No. 4 entitled, How to Define and Determine Reference Intervals in the Clinical Laboratory; Approved Guideline Second Edition, non parametric approach. Laboratories will be required to submit 20 results for each analyte, validated from normal/healthy individuals. Exclusionary criteria will be provided to facilitate identification of appropriate donors. In addition, the participating laboratory will submit testing methods and instruments as well as gender, age, and race of each donor, using classifications from the United States Office of Management and Budget, Revisions to the Standards for the Classification of Federal Data on Race and Ethnicity (Federal Register Notice, October 30, 1997). Laboratories participating in the RRS and RRS2 will receive a summary report including the reference interval for each analyte for which data is submitted. The reference intervals will be provided by platform. In February 2007 participants will be requested to provide their instruments/reagents/methods to ensure that the minimum number of data sets are available per platform for analysis. In addition, laboratories will be provided with exclusionary criteria for potential donors. All donor results should be returned to the CAP for analysis, including those that may be outside of your laboratory s established reference interval. Note: The College had determined that Institutional Review Board (IRB) review is not routinely required to participate in this reference interval service. However, if the laboratory is in an instituion that requires IRB review to conduct reference interval studies, be advised that the deadline to return donor results to the CAP will be May. Shipment A May Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 91

16 Option 1 # for Customer Contact Center Survey Shipment Instrument A B C Spectrophotometer Linearity ph Meters: Buffers for ph measurements Wavelength and Photometric Calibration: Acid potassium dichromate solutions absorbance check, autodilutor check Holmium oxide peak absorbance Thomson s solutions wavelength and photometric calibration Analytical balance Fluorescent microscopes Microtiter plate reader linearity Ocular micrometer Osmometer Pipette calibration, gravimetric Adjustable micropipette calibration verification/linearity Refractometer PRICE $462 Instrumentation I Survey I is designed as an assessment tool for instruments not routinely challenged during the proficiency testing process. Linearity results (forward and reverse) for the spectrophotometer and microtiter plate reader are evaluated by linear regression methods. Appropriate material will be provided to assess important functional parameters, including accuracy and linearity. Please note that some challenges in the I Survey, B shipment, may contain chemically hazardous material and will require special handling. The kit instructions and the specimen vials will identify if any chemically hazardous material is present. Shipment A April 2 Shipment B July 30 Shipment C December 3 92 Calibration Verification/Linearity and Instrumentation College of American Pathologists

17 Serum Carry Over Survey SCO SCO Creatinine hcg Lactate dehydrogenase (LD) Phenytoin PRICE $346 The Survey SCO is designed to help participants prove or disprove instrument sample probe carry over. Multiple kits may be purchased. Each shipment of SCO will consist of a 10.0-mL liquid serum specimen low vial and a 5.0-mL liquid serum high vial. The expiration date of this material is May 31, A calculation is provided in the kit instructions to assist the participants in determining their instrument sample probe carry over; therefore, data need not be returned to the CAP. Ship Date Shipment A May 14 Urine Toxicology Carry Over Survey UTCO UTCO Benzoylecgonine Delta-9-THC-COOH Opiates Propoxyphene PRICE $296 The Survey UTCO is designed to help participants evaluate instrument sample probe carry over. Multiple kits may be purchased. Each shipment of UTCO will consist of a 40.0-mL liquid urine specimen low vial and a 40.0-mL liquid urine high vial. The expiration date of this material is May 31, A calculation is provided in the kit instructions to assist the participants in determining their instrument sample probe carry over; therefore, data need not be returned to the CAP. Ship Date Shipment A May Surveys & Anatomic Pathology Education Programs Calibration Verification/Linearity and Instrumentation 93

18 Option 1 # for Customer Contact Center Survey IFS is designed to assist participants in verifying manufacturing interference specifications and to investigate discrepant results caused by interfering substances such as bilirubin and hemoglobin. Multiple kits may be purchased. Each shipment of IFS will consist of twelve 10.0-mL liquid serum specimens. The expiration date of this material is June 30, Laboratories may send their results to the CAP for evaluation through the expiration date of the material. Participants will receive their evaluations one week after the results have been received by the CAP. Ship Date Shipment A June 11 Interfering Substance Survey IFS Bilirubin Hemoglobin Interferent Interferent Alanine aminotransferase (ALT/SGPT) Albumin Alkaline phosphatase (ALP) Amylase Aspartate aminotransferase (AST/SGOT) Bilirubin, total Calcium Chloride CK 2 (MB) CO 2 Creatine Kinase (CK) Creatinine Gamma glutamyl transferase (GGT) Glucose Iron Lactate dehydrogenase (LD) Lipase Magnesium Osmolality Phosphorus Potassium Protein, total Sodium Urea Uric Acid PRICE $368 College of American Pathologists 94 Calibration Verification/Linearity and Instrumentation