Material Safety Data Sheet

Transcription

1 Material Safety Data Sheet D PANTHENOL Date: March Product and Supplier Description Trade Name: D Panthenol INCI/CHEMICAL Name: Panthenol, Aqua, Pantolactone Supplier: Aromantic Ltd 17 Tytler Street Forres Moray IV36 1EL Tel: Fax: info@aromantic.co.uk REACH Registration Number: (dexpanthenol) 1.1 Relevant identified uses of the substance or mixture and uses advised against Use of the Substance/Mixture: Ingredient for personal care products. 2. Hazards Identification Classification of the substance or mixture Classification (REGULATION (EC) No 1272/2008) Not a hazardous substance or mixture. Classification (67/548/EEC, 1999/45/EC) Not a hazardous substance or mixture. Material Safety Data Sheet. Doc(AD) 1

2 2.2 Label elements Labelling (REGULATION (EC) No 1272/2008) Not a hazardous substance or mixture. Additional Labelling: EUH210 Safety data sheet available on request. 2.3 Other hazards None known. 3. Composition and Ingredient Information Brief description of the product: Mixture (preparation) containing active ingredient and auxiliary substances. Aqueous solution. 3.2 Mixtures Hazardous components Chemical Name CAS-No. EC-No. Registration number Classification (67/548/EEC) Classification (REGULATION (EC) No 1272/2008) Concentration [%] α-hydroxy-β,βdimethyl-γbutyrolactone Xi; R36 Eye Irrit. 2; H319 >= 1 - < 5 For the full text of the R-phrases mentioned in this Section, see Section 16. For the full text of the H-Statements mentioned in this Section, see Section 16. Further ingredients Chemical Name dexpanthenol (provitamin B5) CAS-No. EC-No. Registration number Classification GHS Classification Concentration [%] >= 70 - <= First Aid Measures 4.1 Description of first aid measures General advice: No hazards which require special first aid measures. If inhaled: Move to fresh air. Consult a physician after significant exposure. In case of skin contact: Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. If symptoms persist, call a physician. Material Safety Data Sheet. Doc(AD) 2

3 In case of eye contact: Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If swallowed: Clean mouth with water and drink afterwards plenty of water. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. 4.2 Most important symptoms and effects, both acute and delayed Symptoms: No specific symptoms known. 4.3 Indication of any immediate medical attention and special treatment needed Treatment: Treat symptomatically. 5. Fire Fighting Measures 5.1 Extinguishing media Suitable extinguishing media: Alcohol-resistant foam. Dry chemical. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. 5.2 Special hazards arising from the substance or mixture Specific hazards during firefighting: None known. 5.3 Advice for firefighters Special protective equipment for firefighters: In the event of fire, wear self-contained breathing apparatus. Further information: Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. 6. Measures in case of accidental release 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. 6.2 Environmental precautions Try to prevent the material from entering drains or water courses. 6.3 Methods and materials for containment and cleaning up Wipe up with absorbent material (e.g. cloth, fleece). Keep in suitable, closed containers for disposal. 6.4 Reference to other sections Material Safety Data Sheet. Doc(AD) 3

4 For personal protection see section 8. For disposal considerations see section Handling and Storage 7.1 Precautions for safe handling Advice on safe handling: Avoid contact with skin and eyes. For personal protection see section 8. Advice on protection against fire and explosion: Product will burn under fire conditions. 7.2 Conditions for safe storage, including any incompatibilities Requirements for storage areas and containers: Keep container tightly closed and dry. Storage temperature: < 25 C 7.3 Specific end use(s) Specific use(s): not applicable. 8. Exposure Controls/Personal Protection 8.1 Control parameters Contains no substances with occupational exposure limit values. 8.2 Exposure controls Personal protective equipment Respiratory protection: No personal respiratory protective equipment normally required. Hand protection: Glove material: for example nitrile rubber. Eye protection: Safety glasses with side-shields Skin and body protection: Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 9. Physical and Chemical Properties 9.1 Information on basic physical and chemical properties Appearance: Clear Liquid. Colour: Colourless. Odour: No information available. Odour Threshold: No information available. ph: No data available. Melting point/range: Not determined. Boiling point/boiling range: Not determined. Flash point: > 100 C Evaporation rate: Not determined. Lower explosion limit: Not determined. Material Safety Data Sheet. Doc(AD) 4

5 Upper explosion limit: not determined. Vapour pressure: not determined. Relative vapour density: Not applicable. Density: Not determined. Water solubility: Not determined. Partition coefficient: Noctanol/water: not applicable. Auto-ignition temperature: No data available. Ignition temperature: Not determined. Thermal decomposition: No data available. Viscosity, dynamic: Not determined. Explosive properties: No data available. Oxidizing properties: No data available. 10. Stability and Reactivity 10.1 Reactivity No hazards to be specially mentioned Chemical stability Stable under recommended storage conditions Possibility of hazardous reactions Possible incompatibility with materials listed under section Conditions to avoid Heat Incompatible materials Strong acids and strong bases. Strong oxidizing agents Hazardous decomposition products No decomposition if used as directed. 11. Toxicological Information 11.1 Information on toxicological effects Acute oral toxicity: LD50 (rat): ca mg/kg Acute dermal toxicity: LD50 (rat): > mg/kg Skin corrosion/irritation: No skin irritation (rabbit, OECD Test Guideline 404). No phototoxic skin reaction (guinea pig, CTFA Test Guideline). Material Safety Data Sheet. Doc(AD) 5

6 Serious eye damage/eye irritation: No eye irritation (rabbit, OECD Test Guideline 405). Respiratory or skin sensitisation: Did not cause sensitization. (guinea pig). No photoallergenic skin reaction (guinea pig, CTFA Test Guideline) Genotoxicity in vitro: Not mutagenic (In vitro gene mutation study in mammalian cells, OECD Test Guideline 476) Not genotoxic (Chromosome aberration test in vitro, OECD Test Guideline 473) Carcinogenicity: No indication for carcinogenicity known. Teratogenicity: No human information is available. STOT - repeated exposure: NOAEL (Oral, rat) : 200 mg/kg bw/d Sub-chronic toxicity study (90-day) Experience with human exposure: Hypervitaminosis from provitamin B5 and vitamin B5 is unknown. Experience with human exposure: Skin contact: Allergic contact dermatitis (Cases have been reported rarely.) 12. Ecological Information 12.1 Toxicity Toxicity to fish: Oncorhynchus mykiss (rainbow trout) LC50 (96 h) > mg/l Test substance: Active ingredient (OECD Test Guideline 203) Toxicity to daphnia and other aquatic invertebrates: Daphnia magna (Water flea) EC50 (48 h) > 100 mg/l Test substance: Active ingredient (OECD Test Guideline 202) Toxicity to algae: Material Safety Data Sheet. Doc(AD) 6

7 Desmodesmus subspicatus (green algae) EbC50 (72 h) > 100 mg/l (OECD Test Guideline 201) NOEC (72 h) 100 mg/l Toxicity to bacteria: Activated sludge NOEC 569 mg/l No inhibition was observed under the biodegradation test conditions. (OECD Test Guideline 302B) Pseudomonas putida EC50 (17 h) > mg/l (nominal concentration) (DIN 38412) 12.2 Persistence and degradability Biodegradability: Well inherently biodegradable. 100 % (15 d) (OECD Test Guideline 302B) 12.3 Bioaccumulative potential Bioaccumulation: No data available. Partition coefficient: noctanol/water: Not applicable Mobility in soil Distribution among environmental compartments: No data available Results of PBT and vpvb assessment Assessment: not determined 12.6 Other adverse effects Additional ecological information: There is no data available for this product. 13. Disposal Considerations 13.1 Waste treatment methods Product: Do not contaminate ponds, waterways or ditches with chemical or used container. Do not dispose of waste into sewer. Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging: Dispose of as unused product. Do not re-use empty containers. Material Safety Data Sheet. Doc(AD) 7

8 14. Transport Information 14.1 UN number 14.2 Proper shipping name 14.3 Transport hazard class 14.4 Packing group 14.5 Environmental hazards Material Safety Data Sheet. Doc(AD) 8

9 14.6 Special precautions for user Not classified as dangerous in the meaning of transport regulations Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code No data available. 15. Regulatory Information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture NFPA Classification: Health hazard: 0 Fire Hazard: 1 Reactivity Hazard: Chemical Safety Assessment Not applicable. 16. Other Information Full text of R-phrases referred to under sections 2 and 3 R36 Irritating to eyes. Full text of H-Statements referred to under sections 2 and 3. H319 Causes serious eye irritation. The information contained herein is accurate to the best of our knowledge at the time and on the date shown. No liability can be accepted arising out of the use, application or processing of this product. It is the users responsibility to determine the safe conditions for use of this material. Material Safety Data Sheet. Doc(AD) 9