Neuroanatomy - overview. Lennart Brodin

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1 Neuroanatomy - overview Lennart Brodin

2 brain spinal cord cranial nerves spinal nerves

3 The components of the CNS Telencephalon Diencephalon Brainstem Cerebellum Spinal cord

4 Telencephalon Cerebral Cortex Cerebellum Brainstem

5 Telencephalon: Hemispheres Cerebral Cortex

6 Telencephalon Brainstem Spinal cord Cerebellum

7 Sectioning the brain - nomenclature

8 Coronal section Grey matter: cell bodies of neurons White matter: nerve tracts, Myelin gives the white color

9 Diencephalon Sagittal section Corpus callosum: Connects the hemispheres Telencephalon Thalamus Hypothalamus Cerebellum Brainstem Spinal cord

10 Diencephalon From CNS Visual Perspectives: Telencephalon Thalamus Hypothalamus Hjärnstammen Cerebellum Ryggmärgen Anna Josephsson

11 The Cerebral Cortex Gyrus Sulcus Grey matter White matter

12 Gyrus precentralis: Motor functions Sulcus centralis Gyrus postcentralis: Sensory functions

13 motor sensory The Cerebral Cortex Division into Functional Areas Association areas Primary areas hearing vision

14 Frontal lobe The Cerebral Cortex Division into Lobes Sulcus centralis Parietal lobe Temporal lobe Occipital lobe

15 Frontal lobe The Cerebral Cortex Division into Lobes Parietal lobe Occipital lobe Temporal lobe

16 Localization of functions to lobes Hjässlob Tinninglob Nacklob

17 The Frontal lobe 1848: The famous case of the railway worker Phineas Gage gave the first insigths into the functions of the frontal lobe

18 The Frontal lobe

19 Personality Motivation Planning Decision-making Social skills The Frontal lobe

20 Temporallob The temporal lobe recognition

21 Activation of the temporal lobe during recognition of a known face fmri signal indicates increased activity

22 The parietal lobe attention Temporallob

23 Damage of the right parietal lobe

24 Damage of the right parietal lobe

25 Recent data: The temporal lobe is also involved The parietal lobe attention The posterior temporal lobe Temporallob

26 The occipital lobe Temporallob Receives and processes visual information

27 Language: specific regions in the frontal and temporal lobes

28 Language: specific regions in the frontal and temporal lobes Wernickes area: language perception Damage results in sensory aphasia Broca s area: language expression Damage results in motor aphasia

29 Subcortikal nuclei Telencephalon: The basal ganglia Nucleus caudatus Striatum Putamen Globus pallidus Motor control Cognition Emotions

30 The Basal Ganglia Nucleus caudatus Putamen

31 The Basal Ganglia coronal section Nucleus caudatus Putamen

32 The Basal Ganglia coronal section nucleus caudatus putamen globus pallidus

33 The Basal Ganglia coronal section

34 The Basal Ganglia horisontal section Putamen Globus pallidus Nucleus caudatus

35 Thalamus Diencephalon horisontal section

36 Diencephalon Thalamus Nucleus caudatus Putamen

37 Diencephalon Diencephalon coronalsnitt Thalamus Hypothalamus

38 From CNS Visual Perspectives: Thalamus Hypothalamus Anna Josephsson

39 Diencephalon Thalamus: the brains switch board : relays sensory input to the cerebral cortex

40 Thalamus relays sensory input to the cerebral cortex cortex thalamus nerve fiber from the skin

41 Diencephalon Hypothalamus Homeostasis Emotions The pituitary gland

42 The anatomy of emotions The old view of the limbic system

43 The anatomy of emotions The modern view of the limbic system: Anterior part: emotions; Posterior part: memory Amygdala

44 The anatomy of emotions The modern view of the limbic system: Anterior part: emotions; Posterior part: memory

45 Different Forms of Memory Declarative memory Non-declarative memory Memories that can be described in words Can not be described (e.g how to ride a bicycle)

46 Brain structures participating in declarative memory: The posterior part of the limbic system Hippocampus

47 Brain structures participating in declarative memory: The posterior part of the limbic system

48 Hippocampus seen from below (parts of the temporal lobes removed)

49 The Brainstem Mesencephalon Pons Medulla oblongata

50 Cranial nerves emerging from the brainstem mediate sensory and motor functions in the head (I. N. Olfactorii) (II. N. Opticus) III. N.Oculomotorius IV. N.Trochlearis V. N.Trigeminus VI. N. Abducens VII. N. Facialis VIII. N.Vestibulocochlearis IX. N. Glosso -pharyngeus X. N. Vagus XI. N. Accesorius XII. N. Hypoglossus

51 The Reticular Formation Ascending part: Conciousness Descending part: Motor functions

52

53 The Brainstem - Summary Cranial nerves: sensory and motor functions in the head incl eye movements, hearing, balance, inner organs Reticular Formation: Dopamine systems: Serotonin systems: Other functions: consciousness, motor functions motivation, reward, motor functions mood, emotions, hunger-satiety, motor functions breathing, swalloving

54 Cerebellum

55 Cerebellum: connected to pons via the peduncles

56 Pons Peduncle Medulla oblongata

57 Peduncle

58 Fine-tuning of motor functions Motor learning Cognition Cerebellum

59 The Spinal Cord Grey matter cervical White matter thoracic lumbar Dorsal horn - sensory sacral Ventral horn - motor

60 The Spinal Cord sensory nerves motor nerves

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